The network for 'peptidyl threonine phosphorylation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

peptidyl threonine phosphorylation

The phosphorylation of peptidyl-threonine to form peptidyl-O-phospho-L-threonine.

NameDescriptionProbabilityFunc Analog Organism
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence1.000
GSK3Bglycogen synthase kinase 3 beta0.999
MAPK14mitogen-activated protein kinase 140.999
STK11serine/threonine kinase 110.997
CAB39calcium binding protein 390.997
MAPK1mitogen-activated protein kinase 10.997
SMAD2SMAD family member 20.988
SMAD3SMAD family member 30.985
SMAD7SMAD family member 70.981
EGFRepidermal growth factor receptor0.965
SMAD1SMAD family member 10.957
MAPK8mitogen-activated protein kinase 80.949
PRKCAprotein kinase C, alpha0.948
NCF1neutrophil cytosolic factor 10.947
ARRB1arrestin, beta 10.934
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.912
DDB1damage-specific DNA binding protein 1, 127kDa0.891
MAP3K7mitogen-activated protein kinase kinase kinase 70.887
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.886
TGFB1transforming growth factor, beta 10.881
PPP1CCprotein phosphatase 1, catalytic subunit, gamma isozyme0.848
ATF2activating transcription factor 20.842
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.820
FKBP1AFK506 binding protein 1A, 12kDa0.807
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.790
HDAC6histone deacetylase 60.779
ARHGAP10Rho GTPase activating protein 100.718
MDM2Mdm2 p53 binding protein homolog (mouse)0.691
MAP2K4mitogen-activated protein kinase kinase 40.682
NOXA1NADPH oxidase activator 10.668
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.666
BMP2bone morphogenetic protein 20.658
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.647
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.641
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.625
APPamyloid beta (A4) precursor protein0.619
CDK2cyclin-dependent kinase 20.604
TSC22D1TSC22 domain family, member 10.589
PRKAA1protein kinase, AMP-activated, alpha 1 catalytic subunit0.584
SHC1SHC (Src homology 2 domain containing) transforming protein 10.568
SH3KBP1SH3-domain kinase binding protein 10.563
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.515
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.460
SNTA1syntrophin, alpha 1 (dystrophin-associated protein A1, 59kDa, acidic component)0.457
SMAD4SMAD family member 40.446
BIRC3baculoviral IAP repeat containing 30.424
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.417
MAPTmicrotubule-associated protein tau0.413
MDM4Mdm4 p53 binding protein homolog (mouse)0.405
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.374
ARRB2arrestin, beta 20.364
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.341
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.341
TAB1TGF-beta activated kinase 1/MAP3K7 binding protein 10.329
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.329
SPRED1sprouty-related, EVH1 domain containing 10.316
BIRC2baculoviral IAP repeat containing 20.316
TGFBR1transforming growth factor, beta receptor 10.313
CDC37cell division cycle 37 homolog (S. cerevisiae)0.308
DYRK1Bdual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B0.293
JUNjun proto-oncogene0.292
CDK5R1cyclin-dependent kinase 5, regulatory subunit 1 (p35)0.273
SYKspleen tyrosine kinase0.268
AXIN1axin 10.266
SPRY2sprouty homolog 2 (Drosophila)0.262
CLTCclathrin, heavy chain (Hc)0.259
GRIN2Bglutamate receptor, ionotropic, N-methyl D-aspartate 2B0.256
MAPK12mitogen-activated protein kinase 120.248
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.247
FZR1fizzy/cell division cycle 20 related 1 (Drosophila)0.244
STRADASTE20-related kinase adaptor alpha0.242
CAMK2Acalcium/calmodulin-dependent protein kinase II alpha0.241
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.229
TANKTRAF family member-associated NFKB activator0.225
TERF1telomeric repeat binding factor (NIMA-interacting) 10.222
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.221
TP53tumor protein p530.216
SMAD5SMAD family member 50.199
BMPR1Abone morphogenetic protein receptor, type IA0.195
BCL2L1BCL2-like 10.194
CDK1cyclin-dependent kinase 10.186
SKIv-ski sarcoma viral oncogene homolog (avian)0.180
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.176
CHEK2CHK2 checkpoint homolog (S. pombe)0.176
UHRF2ubiquitin-like with PHD and ring finger domains 20.173
CAMK2Bcalcium/calmodulin-dependent protein kinase II beta0.169
MGEA5meningioma expressed antigen 5 (hyaluronidase)0.156
RIPK3receptor-interacting serine-threonine kinase 30.151
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.150
RAB6ARAB6A, member RAS oncogene family0.147
TP53BP2tumor protein p53 binding protein, 20.144
APCadenomatous polyposis coli0.143
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.142
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.138
UNC119unc-119 homolog (C. elegans)0.138
SPRY4sprouty homolog 4 (Drosophila)0.133
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.132
MAP3K3mitogen-activated protein kinase kinase kinase 30.131
PRKCBprotein kinase C, beta0.129
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
hlh-30Protein HLH-300.011
daf-19Protein DAF-190.011
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mapk3mitogen-activated protein kinase 30.251
mapk1mitogen-activated protein kinase 10.227
lppLIM domain containing preferred translocation partner in lipoma0.207
mxi1max interacting protein0.149
smad2MAD homolog 2 (Drosophila)0.115
spry2sprouty homolog 20.092
gpc4glypican 40.092
aurkbaurora kinase B0.090
stk25bserine/threonine kinase 25b0.087
plxnb2aplexin b2a0.085
spns2spinster homolog 2 (Drosophila)0.079
top2atopoisomerase (DNA) II alpha0.073
ncapd2non-SMC condensin I complex, subunit D20.072
ventventral expressed homeobox0.070
bmp7abone morphogenetic protein 7a0.068
camk2g2calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma 20.068
setd7SET domain containing (lysine methyltransferase) 70.065
sdc2syndecan 20.063
ptpraprotein tyrosine phosphatase, receptor type, A0.063
dlatdihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)0.060
etaa1Ewing tumor-associated antigen 10.059
gro1groucho 10.059
LOC100149148novel protein similar to myosin heavy chain 4 (myhc4)0.058
kctd15apotassium channel tetramerisation domain containing 15a0.055
s1pr2sphingosine-1-phosphate receptor 20.055
pfn1profilin 10.055
onecut1one cut domain, family member 10.055
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.053
smarca2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.052
unguracil-DNA glycosylase0.052
dip2cDIP2 disco-interacting protein 2 homolog C (Drosophila)0.051
mef2dmyocyte enhancer factor 2d0.051
skianuclear oncoprotein skia0.051
ptenaphosphatase and tensin homolog A0.050
brd4bromodomain containing 40.050
dpysl5bdihydropyrimidinase-like 5b0.047
mapk6mitogen-activated protein kinase 60.047
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.046
pabpc1bpoly A binding protein, cytoplasmic 1 b0.046
acad11acyl-Coenzyme A dehydrogenase family, member 110.045
stmn4lstathmin-like 4, like0.045
gga1golgi associated, gamma adaptin ear containing, ARF binding protein 10.045
ccnb1cyclin B10.045
scribscribbled homolog (Drosophila)0.044
sox11bSRY-box containing gene 11b0.043
ccna2cyclin A20.043
mapk12mitogen-activated protein kinase 120.041
smyd1aSET and MYND domain containing 1a0.041
tspan7btetraspanin 7b0.040
syt4synaptotagmin IV0.040
mfn2mitofusin 20.039
spon2aspondin 2a, extracellular matrix protein0.039
ythdf1YTH domain family, member 10.039
prickle2prickle-like 2 (Drosophila)0.039
aim1aabsent in melanoma 1a0.039
dkk1bdickkopf 1b0.039
sass6spindle assembly 6 homolog (C. elegans)0.038
cdc16cell division cycle 16 homolog (S. cerevisiae)0.038
eef2kelongation factor-2 kinase0.037
clasp2cytoplasmic linker associated protein 20.037
ppp1cblprotein phosphatase 1, catalytic subunit, beta isoform, like0.037
ccnb2cyclin B20.037
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.036
crfb5cytokine receptor family member b50.036
arglu1aarginine and glutamate rich 1a0.036
upf1upf1 regulator of nonsense transcripts homolog (yeast)0.036
camk2d2calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 20.036
fkbp1bFK506 binding protein 1b0.036
gro2groucho 20.035
plekha1pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 10.035
wdhd1WD repeat and HMG-box DNA binding protein 10.035
ogt.1O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 10.035
vedventrally expressed dharma/bozozok antagonist0.035
rcbtb1regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 10.034
camk2d1calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 10.034
bub3BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast)0.034
ints6integrator complex subunit 60.033
gdap1ganglioside-induced differentiation-associated protein 10.033
efnb2aephrin B2a0.032
ldb1aLIM-domain binding factor 1a0.032
scinlascinderin like a0.032
tmem59ltransmembrane protein 59-like and transmembrane protein 59-like0.032
arpp19acAMP-regulated phosphoprotein 19a0.032
msi2bmusashi homolog 2b (Drosophila)0.031
tubg1tubulin, gamma 10.031
LOC100536090targeting protein for Xklp2-B-like0.031
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
MadMothers against dpp0.739
Pk61CProtein kinase 61C0.628
Akt1CG4006 gene product from transcript CG4006-RA0.441
ninaEneither inactivation nor afterpotential E0.432
Arr2Arrestin 20.356
SnooSno oncogene0.316
gbbglass bottom boat0.309
G-oalpha47AG protein oalpha 47A0.297
inaCinactivation no afterpotential C0.290
inaDinactivation no afterpotential D0.276
Pi3K92ECG4141 gene product from transcript CG4141-RB0.257
InRInsulin-like receptor0.236
dallydivision abnormally delayed0.233
SaraSmad anchor for receptor activation0.226
norpAno receptor potential A0.215
myoglianinCG1838 gene product from transcript CG1838-RD0.180
EgfrEpidermal growth factor receptor0.166
witwishful thinking0.163
bratbrain tumor0.162
PknProtein kinase related to protein kinase N0.145
Ext2CG8433 gene product from transcript CG8433-RA0.141
cicubitus interruptus0.141
retinophilinCG10233 gene product from transcript CG10233-RA0.128
EcREcdysone receptor0.116
SmoxSmad on X0.114
RhebCG1081 gene product from transcript CG1081-RA0.112
sosine oculis0.107
NFATNFAT homolog0.104
cenG1Acentaurin gamma 1A0.098
CG9339CG9339 gene product from transcript CG9339-RG0.098
Plc21CPhospholipase C at 21C0.095
AdarAdenosine deaminase acting on RNA0.094
aPKCatypical protein kinase C0.093
unc-104CG8566 gene product from transcript CG8566-RB0.092
CG13792CG13792 gene product from transcript CG13792-RA0.090
CG32372CG32372 gene product from transcript CG32372-RA0.079
ninaCneither inactivation nor afterpotential C0.077
drkdownstream of receptor kinase0.077
fz2frizzled 20.072
CG42574CG42574 gene product from transcript CG42574-RE0.071
Pde8Phosphodiesterase 80.070
Bre1CG10542 gene product from transcript CG10542-RA0.067
A2bp1Ataxin-2 binding protein 10.064
Act57BActin 57B0.063
Smg1CG32743 gene product from transcript CG32743-RA0.061
Rab30CG9100 gene product from transcript CG9100-RB0.060
par-1CG8201 gene product from transcript CG8201-RA0.058
CG9297CG9297 gene product from transcript CG9297-RB0.058
Rh3Rhodopsin 30.056
rdgBretinal degeneration B0.054
Rya-r44FRyanodine receptor 44F0.053
stcksteamer duck0.052
Gbeta76CG protein beta-subunit 76C0.051
CG31146CG31146 gene product from transcript CG31146-RD0.049
Ten-mTenascin major0.047
ImpL2Ecdysone-inducible gene L20.046
Pur-alphaPurine-rich binding protein-alpha0.045
trpmltransient receptor potential mucolipin0.044
Cdk4Cyclin-dependent kinase 40.044
boibrother of iHog0.044
Applbeta amyloid protein precursor-like0.044
CdsACDP diglyceride synthetase0.043
Pka-C1cAMP-dependent protein kinase 10.043
CblCG7037 gene product from transcript CG7037-RB0.043
CG8090CG8090 gene product from transcript CG8090-RB0.042
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mapk14mitogen-activated protein kinase 140.999
Smad3MAD homolog 3 (Drosophila)0.996
Gsk3bglycogen synthase kinase 3 beta0.993
Axin1axin 10.990
Mdm2transformed mouse 3T3 cell double minute 20.987
Apcadenomatosis polyposis coli0.975
Ptenphosphatase and tensin homolog0.975
Ctnnb1catenin (cadherin associated protein), beta 10.968
Smad4MAD homolog 4 (Drosophila)0.907
Trp53transformation related protein 530.827
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.813
Map3k7mitogen-activated protein kinase kinase kinase 70.743
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.729
Tgfbr2transforming growth factor, beta receptor II0.658
Bmpr1abone morphogenetic protein receptor, type 1A0.656
Acvr1activin A receptor, type 10.603
Atf2activating transcription factor 20.594
Smad1MAD homolog 1 (Drosophila)0.562
Mapkapk2MAP kinase-activated protein kinase 20.475
Mapk8mitogen-activated protein kinase 80.446
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.438
Enahenabled homolog (Drosophila)0.389
Ccnb1cyclin B10.389
Shc1src homology 2 domain-containing transforming protein C10.373
RictorRPTOR independent companion of MTOR, complex 20.364
Rnf111ring finger 1110.355
Tgfbr1transforming growth factor, beta receptor I0.340
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.334
Actn2actinin alpha 20.302
Fbxw7F-box and WD-40 domain protein 70.301
Clk4CDC like kinase 40.291
BrafBraf transforming gene0.282
Prkceprotein kinase C, epsilon0.276
Dkk1dickkopf homolog 1 (Xenopus laevis)0.273
Bak1BCL2-antagonist/killer 10.273
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.244
Rargretinoic acid receptor, gamma0.239
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.235
Ccnl2cyclin L20.234
Mtap2microtubule-associated protein 20.224
Mknk2MAP kinase-interacting serine/threonine kinase 20.222
Ccnt2cyclin T20.215
Smad6MAD homolog 6 (Drosophila)0.215
Clk1CDC-like kinase 10.215
Mapkap1mitogen-activated protein kinase associated protein 10.208
Capn1calpain 10.207
Bcl2B-cell leukemia/lymphoma 20.204
Rock2Rho-associated coiled-coil containing protein kinase 20.202
Smad7MAD homolog 7 (Drosophila)0.197
Homer1homer homolog 1 (Drosophila)0.197
Ldb3LIM domain binding 30.197
Vaspvasodilator-stimulated phosphoprotein0.180
Ccnb2cyclin B20.178
Birc5baculoviral IAP repeat-containing 50.174
Mapk1mitogen-activated protein kinase 10.165
Dlg1discs, large homolog 1 (Drosophila)0.164
Ccnfcyclin F0.159
Cdk1cyclin-dependent kinase 10.157
Aurkbaurora kinase B0.148
Kif20akinesin family member 20A0.142
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.142
Rhogras homolog gene family, member G0.140
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.137
Il6stinterleukin 6 signal transducer0.132
Pik3r1phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)0.127
Gab1growth factor receptor bound protein 2-associated protein 10.126
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.126
Tgfb1transforming growth factor, beta 10.125
Akap8lA kinase (PRKA) anchor protein 8-like0.124
Traf6TNF receptor-associated factor 60.123
Usp9xubiquitin specific peptidase 9, X chromosome0.122
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.116
Fgfr3fibroblast growth factor receptor 30.114
Esr1estrogen receptor 1 (alpha)0.114
Ckap2cytoskeleton associated protein 20.112
Kif22kinesin family member 220.112
Prc1protein regulator of cytokinesis 10.111
Vhlvon Hippel-Lindau tumor suppressor0.110
Huwe1HECT, UBA and WWE domain containing 10.110
Hipk3homeodomain interacting protein kinase 30.107
Gnai2guanine nucleotide binding protein (G protein), alpha inhibiting 20.107
Lrp6low density lipoprotein receptor-related protein 60.104
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.104
BaxBCL2-associated X protein0.103
Inhbbinhibin beta-B0.102
Cdca8cell division cycle associated 80.102
Zmym2zinc finger, MYM-type 20.101
Nos3nitric oxide synthase 3, endothelial cell0.092
Mknk1MAP kinase-interacting serine/threonine kinase 10.091
OgtO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)0.090
Cdh5cadherin 50.089
Pde7aphosphodiesterase 7A0.087
Fliiflightless I homolog (Drosophila)0.087
Ano1anoctamin 1, calcium activated chloride channel0.087
Sox9SRY-box containing gene 90.087
Ccna2cyclin A20.086
Erbb2ipErbb2 interacting protein0.085
Pik3caphosphatidylinositol 3-kinase, catalytic, alpha polypeptide0.084
Mapk11mitogen-activated protein kinase 110.084
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RGD1359529similar to chromosome 1 open reading frame 630.044
Git1G protein-coupled receptor kinase interacting ArfGAP 10.022
Smad7SMAD family member 70.019
Gna12guanine nucleotide binding protein (G protein) alpha 120.019
Top2btopoisomerase (DNA) II beta0.017
SnrkSNF related kinase0.016
Fgfr2fibroblast growth factor receptor 20.015
Stxbp5syntaxin binding protein 5 (tomosyn)0.013
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.011
Akap1A kinase (PRKA) anchor protein 10.011
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism