The network for 'forebrain regionalization' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

forebrain regionalization

The regionalization process resulting in the creation of areas within the forebrain that will direct the behavior of cell migration in differentiation as the forebrain develops.

NameDescriptionProbabilityFunc Analog Organism
BMPR1Abone morphogenetic protein receptor, type IA1.000
PMLpromyelocytic leukemia1.000
PAX8paired box 80.995
FSTL1follistatin-like 10.948
PTCH1patched 10.945
LGALS8lectin, galactoside-binding, soluble, 80.913
MDFIMyoD family inhibitor0.879
FGF8fibroblast growth factor 8 (androgen-induced)0.846
CTBP2C-terminal binding protein 20.818
LRP6low density lipoprotein receptor-related protein 60.779
NKX2-1NK2 homeobox 10.753
LHX2LIM homeobox 20.715
FGF3fibroblast growth factor 30.630
HES2hairy and enhancer of split 2 (Drosophila)0.621
HOXB1homeobox B10.594
EYA2eyes absent homolog 2 (Drosophila)0.586
ZFYVE9zinc finger, FYVE domain containing 90.582
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.575
PAX2paired box 20.563
FOXE1forkhead box E1 (thyroid transcription factor 2)0.553
SOX1SRY (sex determining region Y)-box 10.531
CDX2caudal type homeobox 20.527
RAXretina and anterior neural fold homeobox0.493
PAX7paired box 70.438
FZD1frizzled homolog 1 (Drosophila)0.435
FOXD3forkhead box D30.433
GSK3Aglycogen synthase kinase 3 alpha0.424
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.423
TERTtelomerase reverse transcriptase0.413
LHX5LIM homeobox 50.396
SFRP1secreted frizzled-related protein 10.376
C1QL1complement component 1, q subcomponent-like 10.373
WNT1wingless-type MMTV integration site family, member 10.366
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.349
HOXD9homeobox D90.341
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.341
TLX2T-cell leukemia homeobox 20.341
FOXB1forkhead box B10.333
FZD8frizzled homolog 8 (Drosophila)0.326
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.316
WNT3wingless-type MMTV integration site family, member 30.314
HOXD13homeobox D130.305
FOXF2forkhead box F20.299
FGF18fibroblast growth factor 180.295
SIX6SIX homeobox 60.294
WIF1WNT inhibitory factor 10.282
FOXA2forkhead box A20.280
SMAD7SMAD family member 70.280
OTPorthopedia homeobox0.276
BHLHE23basic helix-loop-helix family, member e230.273
EN1engrailed homeobox 10.268
BMP4bone morphogenetic protein 40.263
ALX4ALX homeobox 40.256
SHHsonic hedgehog0.254
HOXA11homeobox A110.254
COL2A1collagen, type II, alpha 10.250
AQP5aquaporin 50.249
DVL2dishevelled, dsh homolog 2 (Drosophila)0.247
STK36serine/threonine kinase 360.242
CTBP1C-terminal binding protein 10.242
SLC18A3solute carrier family 18 (vesicular acetylcholine), member 30.239
ALX3ALX homeobox 30.236
NPAS1neuronal PAS domain protein 10.226
OTX2orthodenticle homeobox 20.226
MCCmutated in colorectal cancers0.222
FOXL1forkhead box L10.204
MSX1msh homeobox 10.204
GBX2gastrulation brain homeobox 20.203
TP73tumor protein p730.198
CRLF1cytokine receptor-like factor 10.191
DLX4distal-less homeobox 40.191
DVL1dishevelled, dsh homolog 1 (Drosophila)0.190
DIO3deiodinase, iodothyronine, type III0.186
WNT4wingless-type MMTV integration site family, member 40.185
HOXD11homeobox D110.174
CSNK1Ecasein kinase 1, epsilon0.173
POU3F1POU class 3 homeobox 10.173
SIX1SIX homeobox 10.172
NKX3-2NK3 homeobox 20.170
VSX1visual system homeobox 10.170
NKX2-8NK2 homeobox 80.168
HTR1A5-hydroxytryptamine (serotonin) receptor 1A0.166
HS3ST6heparan sulfate (glucosamine) 3-O-sulfotransferase 60.166
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.165
SOX21SRY (sex determining region Y)-box 210.163
SFRP5secreted frizzled-related protein 50.162
IHHIndian hedgehog0.162
TBX1T-box 10.161
BARX1BARX homeobox 10.157
SOX2SRY (sex determining region Y)-box 20.156
PDX1pancreatic and duodenal homeobox 10.156
MAXMYC associated factor X0.154
HIC1hypermethylated in cancer 10.150
MESP1mesoderm posterior 1 homolog (mouse)0.150
POU3F2POU class 3 homeobox 20.147
WNT10Awingless-type MMTV integration site family, member 10A0.145
HMX1H6 family homeobox 10.142
FOXN4forkhead box N40.139
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
fgf8afibroblast growth factor 8 a0.984
mab21l2mab-21-like 20.980
pax2apaired box gene 2a0.957
rx3retinal homeobox gene 30.942
six3asine oculis homeobox homolog 3a0.921
otx1borthodenticle homolog 1b0.898
fgf3fibroblast growth factor 30.895
bmp2bbone morphogenetic protein 2b0.894
barhl2BarH-like 20.844
hnf1baHNF1 homeobox Ba0.830
otx2orthodenticle homolog 20.828
nr2e1nuclear receptor subfamily 2, group E, member 10.811
foxg1aforkhead box G1a0.808
pax6bpaired box gene 6b0.757
dbx1adeveloping brain homeobox 1a0.749
tbx1T-box 10.742
flhfloating head0.738
six3bsine oculis homeobox homolog 3b0.736
cdh2cadherin 2, neuronal0.668
fezf2FEZ family zinc finger 20.668
emx3empty spiracles homeobox 30.660
lef1lymphocyte enhancer binding factor 10.657
robo3roundabout homolog 30.649
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.643
shhasonic hedgehog a0.629
gbx2gastrulation brain homeo box 20.619
pax6apaired box gene 6a0.616
zic1zic family member 1 (odd-paired homolog, Drosophila)0.599
ndr2nodal-related 20.587
lhx5LIM homeobox 50.577
bmp4bone morphogenetic protein 40.540
sox1aSRY-box containing gene 1a0.528
sox2SRY-box containing gene 20.519
apcadenomatosis polyposis coli0.501
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.501
meis2.1myeloid ecotropic viral integration site 2.10.463
lhx1aLIM homeobox 1a0.451
pou3f3bPOU class 3 homeobox 3b0.449
hoxa9ahomeo box A9a0.444
wnt4awingless-type MMTV integration site family, member 4a0.438
wnt5bwingless-type MMTV integration site family, member 5b0.433
znf503zinc finger protein 5030.425
lhx2bLIM homeobox 2b0.417
wnt11wingless-type MMTV integration site family, member 110.416
olig2oligodendrocyte lineage transcription factor 20.377
foxn4forkhead box N40.375
wnt8bwingless-type MMTV integration site family, member 8b0.373
lmo3LIM domain only 30.365
hoxd4ahomeo box D4a0.364
epb4.1l4erythrocyte protein band 4.1-like 40.363
ascl1aachaete-scute complex-like 1a (Drosophila)0.349
bocbrother of CDO0.325
ptch1patched 10.306
rfx2regulatory factor X, 2 (influences HLA class II expression)0.304
fzd10frizzled homolog 100.297
pbx4pre-B-cell leukemia transcription factor 40.293
pax8paired box gene 80.269
tfap2atranscription factor AP-2 alpha0.265
mibmind bomb0.259
wnt1wingless-type MMTV integration site family, member 10.251
lfnglunatic fringe homolog0.251
nkx2.2aNK2 transcription factor related 2a0.249
foxp2forkhead box P20.235
sox11bSRY-box containing gene 11b0.232
spry2sprouty homolog 20.229
irx7iroquois homeobox protein 70.216
dmbx1adiencephalon/mesencephalon homeobox 1a0.212
sema3aasemaphorin 3aa0.208
dbx1bdeveloping brain homeobox 1b0.203
aldh1a2aldehyde dehydrogenase 1 family, member A20.189
otpborthopedia homolog b0.187
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.186
shhbsonic hedgehog b0.180
ephb4beph receptor B4b0.176
tlcsecreted frizzled-related protein0.165
eng2aengrailed 2a0.164
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.164
fzd9bfrizzled homolog 9b0.162
fzd5frizzled homolog 50.156
nkx2.1aNK2 homeobox 1a0.153
pou3f1POU class 3 homeobox 10.153
tll1tolloid-like 10.152
sox9aSRY-box containing gene 9a0.148
gli2aGLI-Kruppel family member GLI2a0.146
hhiphedgehog interacting protein0.144
gdnfglial cell derived neurotrophic factor0.143
emx1empty spiracles homeobox 10.139
hey1hairy/enhancer-of-split related with YRPW motif 10.133
her5hairy-related 50.130
fgfr3fibroblast growth factor receptor 30.129
wnt7bbwingless-type MMTV integration site family, member 7Bb0.128
arxaristaless related homeobox0.126
bonbonnie and clyde0.126
six2asine oculis-related homeobox 2a0.125
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Pax2paired box gene 21.000
Fgf8fibroblast growth factor 81.000
Gli3GLI-Kruppel family member GLI30.999
Pitx2paired-like homeodomain transcription factor 20.999
Lhx1LIM homeobox protein 10.998
Rargretinoic acid receptor, gamma0.998
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.997
Sox9SRY-box containing gene 90.997
Dlx5distal-less homeobox 50.996
Emx2empty spiracles homolog 2 (Drosophila)0.996
Gli2GLI-Kruppel family member GLI20.995
Pax3paired box gene 30.993
Fgfr2fibroblast growth factor receptor 20.993
Tbx1T-box 10.993
Hand2heart and neural crest derivatives expressed transcript 20.993
Hand1heart and neural crest derivatives expressed transcript 10.992
Tcfap2atranscription factor AP-2, alpha0.991
Hoxa1homeobox A10.991
Pax6paired box gene 60.991
Msx1homeobox, msh-like 10.987
Emx1empty spiracles homolog 1 (Drosophila)0.983
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.982
Fgf10fibroblast growth factor 100.982
Smosmoothened homolog (Drosophila)0.976
Isl1ISL1 transcription factor, LIM/homeodomain0.975
Pitx1paired-like homeodomain transcription factor 10.971
Lmx1aLIM homeobox transcription factor 1 alpha0.953
Sox2SRY-box containing gene 20.950
Eya1eyes absent 1 homolog (Drosophila)0.950
Foxc1forkhead box C10.946
Wnt3awingless-related MMTV integration site 3A0.943
Ror2receptor tyrosine kinase-like orphan receptor 20.941
Gbx2gastrulation brain homeobox 20.934
Foxg1forkhead box G10.926
Foxc2forkhead box C20.917
Otx1orthodenticle homolog 1 (Drosophila)0.912
Hoxa2homeobox A20.912
Pax8paired box gene 80.909
Rarbretinoic acid receptor, beta0.903
Hoxd3homeobox D30.899
Fgfr3fibroblast growth factor receptor 30.897
Tbx3T-box 30.874
Hoxa3homeobox A30.873
Pou3f3POU domain, class 3, transcription factor 30.863
Vangl2vang-like 2 (van gogh, Drosophila)0.848
Bmp7bone morphogenetic protein 70.839
Hoxb3homeobox B30.815
Prrx1paired related homeobox 10.808
Ascl1achaete-scute complex homolog 1 (Drosophila)0.799
Lhx3LIM homeobox protein 30.776
En1engrailed 10.770
Dkk1dickkopf homolog 1 (Xenopus laevis)0.761
Hes5hairy and enhancer of split 5 (Drosophila)0.757
Gscgoosecoid homeobox0.754
Alx4aristaless-like homeobox 40.754
Insm1insulinoma-associated 10.749
Lhx5LIM homeobox protein 50.731
Hoxd13homeobox D130.728
Col2a1collagen, type II, alpha 10.724
Foxf1aforkhead box F1a0.719
Fgfr1fibroblast growth factor receptor 10.702
Fgf3fibroblast growth factor 30.696
Sox3SRY-box containing gene 30.692
Wt1Wilms tumor 1 homolog0.685
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.652
Nkx3-2NK3 homeobox 20.640
Hoxd11homeobox D110.633
Rararetinoic acid receptor, alpha0.605
Smad6MAD homolog 6 (Drosophila)0.598
Bmp4bone morphogenetic protein 40.595
Zic3zinc finger protein of the cerebellum 30.593
Nr5a1nuclear receptor subfamily 5, group A, member 10.590
Alx3aristaless-like homeobox 30.549
Vax1ventral anterior homeobox containing gene 10.542
Hmx3H6 homeobox 30.538
Fgf15fibroblast growth factor 150.534
Gdnfglial cell line derived neurotrophic factor0.531
Lef1lymphoid enhancer binding factor 10.497
Foxa2forkhead box A20.496
Msx2homeobox, msh-like 20.486
Pax9paired box gene 90.485
Gdf3growth differentiation factor 30.476
Atoh7atonal homolog 7 (Drosophila)0.476
UncxUNC homeobox0.469
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.468
Ctnnb1catenin (cadherin associated protein), beta 10.468
Hoxa13homeobox A130.457
Hmx1H6 homeobox 10.453
Neurog1neurogenin 10.446
Nkx6-1NK6 homeobox 10.442
Dlx6distal-less homeobox 60.431
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.416
Gata4GATA binding protein 40.408
Chd7chromodomain helicase DNA binding protein 70.401
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism