The network for 'interleukin 8 mediated signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

interleukin 8 mediated signaling pathway

A series of molecular signals initiated by the binding of interleukin-8 to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription.

NameDescriptionProbabilityFunc Analog Organism
CCL5chemokine (C-C motif) ligand 51.000
CCR2chemokine (C-C motif) receptor 21.000
CCR5chemokine (C-C motif) receptor 50.998
IL2RBinterleukin 2 receptor, beta0.992
CCL22chemokine (C-C motif) ligand 220.967
CXCL9chemokine (C-X-C motif) ligand 90.935
IRF4interferon regulatory factor 40.926
IFNGinterferon, gamma0.914
CCR4chemokine (C-C motif) receptor 40.911
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.862
CXCR3chemokine (C-X-C motif) receptor 30.832
CCR7chemokine (C-C motif) receptor 70.831
CD40LGCD40 ligand0.733
IL16interleukin 16 (lymphocyte chemoattractant factor)0.617
CCL4chemokine (C-C motif) ligand 40.608
CXCR6chemokine (C-X-C motif) receptor 60.554
SLAMF7SLAM family member 70.552
LTAlymphotoxin alpha (TNF superfamily, member 1)0.525
CCR1chemokine (C-C motif) receptor 10.505
IL10interleukin 100.435
IL10RAinterleukin 10 receptor, alpha0.397
LAIR1leukocyte-associated immunoglobulin-like receptor 10.342
CD86CD86 molecule0.310
CCL3chemokine (C-C motif) ligand 30.293
TNFSF8tumor necrosis factor (ligand) superfamily, member 80.278
CXCL13chemokine (C-X-C motif) ligand 130.273
CXCL11chemokine (C-X-C motif) ligand 110.218
CXCR5chemokine (C-X-C motif) receptor 50.215
CLEC7AC-type lectin domain family 7, member A0.187
CXCL10chemokine (C-X-C motif) ligand 100.182
CCR6chemokine (C-C motif) receptor 60.157
IL1R2interleukin 1 receptor, type II0.150
LAG3lymphocyte-activation gene 30.146
CCL7chemokine (C-C motif) ligand 70.139
CCL19chemokine (C-C motif) ligand 190.129
CCL11chemokine (C-C motif) ligand 110.121
KLRD1killer cell lectin-like receptor subfamily D, member 10.103
TNFRSF9tumor necrosis factor receptor superfamily, member 90.098
GZMKgranzyme K (granzyme 3; tryptase II)0.098
CLEC4AC-type lectin domain family 4, member A0.095
IL21Rinterleukin 21 receptor0.093
CD2CD2 molecule0.087
IL2RGinterleukin 2 receptor, gamma0.086
TNFtumor necrosis factor0.085
CD1CCD1c molecule0.085
SPIBSpi-B transcription factor (Spi-1/PU.1 related)0.085
CCL8chemokine (C-C motif) ligand 80.084
PRAF2PRA1 domain family, member 20.082
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.082
LGALS2lectin, galactoside-binding, soluble, 20.078
FASLGFas ligand (TNF superfamily, member 6)0.075
CD80CD80 molecule0.074
CYBBcytochrome b-245, beta polypeptide0.074
P2RY10purinergic receptor P2Y, G-protein coupled, 100.073
CCR3chemokine (C-C motif) receptor 30.072
CD22CD22 molecule0.066
LTBlymphotoxin beta (TNF superfamily, member 3)0.065
IL2RAinterleukin 2 receptor, alpha0.057
FCER2Fc fragment of IgE, low affinity II, receptor for (CD23)0.055
IL18RAPinterleukin 18 receptor accessory protein0.054
TLR2toll-like receptor 20.051
CXCR2chemokine (C-X-C motif) receptor 20.051
DPP4dipeptidyl-peptidase 40.050
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.048
CLEC4EC-type lectin domain family 4, member E0.047
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.046
CD79ACD79a molecule, immunoglobulin-associated alpha0.044
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.043
FGL2fibrinogen-like 20.041
CD28CD28 molecule0.040
IGSF6immunoglobulin superfamily, member 60.040
FCN1ficolin (collagen/fibrinogen domain containing) 10.039
RNASE2ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)0.039
EVI2Becotropic viral integration site 2B0.037
CSF2RAcolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)0.037
CD48CD48 molecule0.036
GNAO1guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O0.035
CCR8chemokine (C-C motif) receptor 80.034
AQP9aquaporin 90.034
IL4interleukin 40.033
EMR1egf-like module containing, mucin-like, hormone receptor-like 10.033
ADAMDEC1ADAM-like, decysin 10.033
IL1RNinterleukin 1 receptor antagonist0.032
ITKIL2-inducible T-cell kinase0.032
CD93CD93 molecule0.032
RGS1regulator of G-protein signaling 10.032
CLEC5AC-type lectin domain family 5, member A0.031
CTLA4cytotoxic T-lymphocyte-associated protein 40.031
SPOCK2sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 20.031
CD19CD19 molecule0.030
GPR18G protein-coupled receptor 180.030
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.030
BIN2bridging integrator 20.029
CCL20chemokine (C-C motif) ligand 200.028
ITGAMintegrin, alpha M (complement component 3 receptor 3 subunit)0.028
IL1Binterleukin 1, beta0.027
SASH3SAM and SH3 domain containing 30.027
LAX1lymphocyte transmembrane adaptor 10.027
CCL13chemokine (C-C motif) ligand 130.026
MS4A6Amembrane-spanning 4-domains, subfamily A, member 6A0.026
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism