The network for 'postreplication repair' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

postreplication repair

The conversion of DNA-damage induced single-stranded gaps into large molecular weight DNA after replication. Includes pathways that remove replication-blocking lesions in conjunction with DNA replication.

NameDescriptionProbabilityFunc Analog Organism
HIST1H2BDhistone cluster 1, H2bd1.000
HIST1H2BFhistone cluster 1, H2bf1.000
HIST1H2BEhistone cluster 1, H2be1.000
RAD18RAD18 homolog (S. cerevisiae)0.998
HIST1H1Chistone cluster 1, H1c0.998
PCNAproliferating cell nuclear antigen0.997
HIST1H2BHhistone cluster 1, H2bh0.997
HIST1H2AChistone cluster 1, H2ac0.997
HIST1H2BGhistone cluster 1, H2bg0.996
HIST1H2BIhistone cluster 1, H2bi0.994
HIST1H3Dhistone cluster 1, H3d0.989
HIST1H2BKhistone cluster 1, H2bk0.987
HIST1H2BChistone cluster 1, H2bc0.979
HIST2H2AA4histone cluster 2, H2aa40.969
POLE3polymerase (DNA directed), epsilon 3 (p17 subunit)0.959
POLHpolymerase (DNA directed), eta0.951
HIST1H2AEhistone cluster 1, H2ae0.880
HIST2H2BEhistone cluster 2, H2be0.795
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.739
HIST1H2AJhistone cluster 1, H2aj0.674
MSH6mutS homolog 6 (E. coli)0.527
FANCD2Fanconi anemia, complementation group D20.411
REV1REV1 homolog (S. cerevisiae)0.306
HIST1H2AIhistone cluster 1, H2ai0.305
HIST1H3Hhistone cluster 1, H3h0.287
POLIpolymerase (DNA directed) iota0.215
HIST1H4Hhistone cluster 1, H4h0.156
PABPC1poly(A) binding protein, cytoplasmic 10.156
DZIP3DAZ interacting protein 3, zinc finger0.154
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.150
PAN3PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.129
RPA3replication protein A3, 14kDa0.127
WRNWerner syndrome, RecQ helicase-like0.122
HIST1H2AGhistone cluster 1, H2ag0.120
POLD1polymerase (DNA directed), delta 1, catalytic subunit 125kDa0.112
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.111
POLE2polymerase (DNA directed), epsilon 2 (p59 subunit)0.089
ING2inhibitor of growth family, member 20.086
HIST1H2AMhistone cluster 1, H2am0.079
H2AFXH2A histone family, member X0.076
RBBP8retinoblastoma binding protein 80.073
ERCC6excision repair cross-complementing rodent repair deficiency, complementation group 60.063
PAN2PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)0.061
REV3LREV3-like, catalytic subunit of DNA polymerase zeta (yeast)0.059
POLD3polymerase (DNA-directed), delta 3, accessory subunit0.059
RNF11ring finger protein 110.051
POLKpolymerase (DNA directed) kappa0.049
CTDP1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 10.048
HIST1H3Ghistone cluster 1, H3g0.047
GINS2GINS complex subunit 2 (Psf2 homolog)0.044
HIST1H2BJhistone cluster 1, H2bj0.044
HIST1H2BBhistone cluster 1, H2bb0.042
CHRAC1chromatin accessibility complex 10.041
RAD51AP1RAD51 associated protein 10.037
MSH3mutS homolog 3 (E. coli)0.036
ATXN3ataxin 30.032
HIST1H2BMhistone cluster 1, H2bm0.032
TNRC6Btrinucleotide repeat containing 6B0.031
TNRC6Atrinucleotide repeat containing 6A0.031
HIST1H2BOhistone cluster 1, H2bo0.029
HIST1H2ABhistone cluster 1, H2ab0.029
SUPT5Hsuppressor of Ty 5 homolog (S. cerevisiae)0.029
EXO1exonuclease 10.028
GINS1GINS complex subunit 1 (Psf1 homolog)0.028
DR1down-regulator of transcription 1, TBP-binding (negative cofactor 2)0.027
MLH1mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli)0.026
UBE2Nubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast)0.026
CDK5RAP3CDK5 regulatory subunit associated protein 30.026
SHPRHSNF2 histone linker PHD RING helicase0.021
PMS1PMS1 postmeiotic segregation increased 1 (S. cerevisiae)0.021
HIST1H4Dhistone cluster 1, H4d0.021
BRIP1BRCA1 interacting protein C-terminal helicase 10.020
ZNRF1zinc and ring finger 10.019
ANKRD32ankyrin repeat domain 320.019
CLSPNclaspin0.019
NPLOC4nuclear protein localization 4 homolog (S. cerevisiae)0.018
HIST1H2ALhistone cluster 1, H2al0.018
HIST1H4Ehistone cluster 1, H4e0.017
RAD50RAD50 homolog (S. cerevisiae)0.016
MARCH5membrane-associated ring finger (C3HC4) 50.015
HIST2H2AA3histone cluster 2, H2aa30.015
HIST1H1Ehistone cluster 1, H1e0.015
CALCOCO2calcium binding and coiled-coil domain 20.015
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.015
RNF168ring finger protein 1680.014
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.014
PAIP2poly(A) binding protein interacting protein 20.014
TIMELESStimeless homolog (Drosophila)0.014
WWOXWW domain containing oxidoreductase0.013
POLE4polymerase (DNA-directed), epsilon 4 (p12 subunit)0.012
CHEK1CHK1 checkpoint homolog (S. pombe)0.012
UBR1ubiquitin protein ligase E3 component n-recognin 10.012
CBWD2COBW domain containing 20.012
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.012
HIST2H4Bhistone cluster 2, H4b0.012
XAB2XPA binding protein 20.012
HIST1H3Ahistone cluster 1, H3a0.011
HIST1H1Dhistone cluster 1, H1d0.011
PFN1profilin 10.011
PCGF6polycomb group ring finger 60.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mus205mutagen-sensitive 2050.744
rad50CG6339 gene product from transcript CG6339-RD0.666
mus210mutagen-sensitive 2100.551
mus101mutagen-sensitive 1010.508
hayhaywire0.484
RecQ5homolog of RecQ0.415
CG5524CG5524 gene product from transcript CG5524-RA0.414
mus308mutagen-sensitive 3080.398
lokloki0.309
Brca2Breast cancer 2, early onset homolog0.214
mus201mutagen-sensitive 2010.198
mei-9meiotic 90.180
DNApol-etaCG7143 gene product from transcript CG7143-RA0.178
nbsCG6754 gene product from transcript CG6754-RC0.156
nopono poles0.102
okrokra0.091
IrbpInverted repeat-binding protein0.088
Smc5CG32438 gene product from transcript CG32438-RE0.072
mre11meiotic recombination 110.071
Mcm3Minichromosome maintenance 30.068
cnkconnector enhancer of ksr0.065
mus309mutagen-sensitive 3090.064
piepineapple eye0.061
mus304mutagen-sensitive 3040.059
snostrawberry notch0.047
Rev1CG12189 gene product from transcript CG12189-RA0.045
barrbarren0.042
fzyfizzy0.039
Chrac-14CG13399 gene product from transcript CG13399-RA0.036
wdswill die slowly0.036
dmtdalmatian0.034
mei-41meiotic 410.032
RecQ4CG7487 gene product from transcript CG7487-RA0.032
mus301mutagen-sensitive 3010.031
RnrLRibonucleoside diphosphate reductase large subunit0.029
Ercc1CG10215 gene product from transcript CG10215-RA0.029
tefutelomere fusion0.029
mus312mutagen-sensitive 3120.026
Mcm7Minichromosome maintenance 70.025
stnAstoned A0.024
stwlstonewall0.023
CG7376CG7376 gene product from transcript CG7376-RA0.022
CDC45LCG3658 gene product from transcript CG3658-RA0.021
spn-Aspindle A0.021
dpadisc proliferation abnormal0.021
CG5174CG5174 gene product from transcript CG5174-RM0.021
dre4CG1828 gene product from transcript CG1828-RB0.020
Lig4Ligase40.019
CG5931CG5931 gene product from transcript CG5931-RA0.019
AceAcetylcholine esterase0.018
nodno distributive disjunction0.017
Su(z)2Suppressor of zeste 20.017
eghegghead0.017
ltlight0.017
CG3975CG3975 gene product from transcript CG3975-RA0.016
phrphotorepair0.016
Klp61FKinesin-like protein at 61F0.016
Df31Decondensation factor 310.016
CG4680CG4680 gene product from transcript CG4680-RA0.015
ari-1ariadne0.015
Orc5Origin recognition complex subunit 50.015
cavcaravaggio0.015
l(1)G0222lethal (1) G02220.014
fdlfused lobes0.014
Orc2Origin recognition complex subunit 20.014
Nipped-ACG33554 gene product from transcript CG33554-RE0.013
CG14814CG14814 gene product from transcript CG14814-RA0.013
Smg6CG6369 gene product from transcript CG6369-RA0.013
Cks30ACyclin-dependent kinase subunit 30A0.013
Spc105RSpc105-related0.013
CG13350CG13350 gene product from transcript CG13350-RA0.012
PcafCG4107 gene product from transcript CG4107-RA0.012
RpA-70Replication Protein A 700.012
Dp1Dodeca-satellite-binding protein 10.012
alphalphabet0.012
CG11414CG11414 gene product from transcript CG11414-RA0.012
Mnn1Menin 10.012
spn-Bspindle B0.011
CG9776CG9776 gene product from transcript CG9776-RA0.011
eIF-1AEukaryotic initiation factor 1A0.011
Fkbp13CG9847 gene product from transcript CG9847-RC0.011
mu2mutator 20.011
CG9576CG9576 gene product from transcript CG9576-RA0.011
captcapulet0.011
eIF3-S8CG4954 gene product from transcript CG4954-RA0.011
cmetCENP-meta0.011
ogreoptic ganglion reduced0.010
pavpavarotti0.010
ncdnon-claret disjunctional0.010
SMC2CG10212 gene product from transcript CG10212-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Rev1REV1 homolog (S. cerevisiae)0.835
Nbnnibrin0.524
Brca2breast cancer 20.501
Polhpolymerase (DNA directed), eta (RAD 30 related)0.111
Stk11serine/threonine kinase 110.094
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.091
Hprthypoxanthine guanine phosphoribosyl transferase0.075
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.072
Ezh2enhancer of zeste homolog 2 (Drosophila)0.064
Trp53transformation related protein 530.058
Timelesstimeless homolog (Drosophila)0.046
Rb1retinoblastoma 10.041
Atrataxia telangiectasia and Rad3 related0.035
Ube2d3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.032
Mdm2transformed mouse 3T3 cell double minute 20.032
Cdkn1bcyclin-dependent kinase inhibitor 1B0.028
Brca1breast cancer 10.028
Polkpolymerase (DNA directed), kappa0.027
Atmataxia telangiectasia mutated homolog (human)0.027
Apcadenomatosis polyposis coli0.025
Nsfl1cNSFL1 (p97) cofactor (p47)0.023
Chek1checkpoint kinase 1 homolog (S. pombe)0.023
Hsp90ab1heat shock protein 90 alpha (cytosolic), class B member 10.021
Prkdcprotein kinase, DNA activated, catalytic polypeptide0.020
Ube2nubiquitin-conjugating enzyme E2N0.020
Polipolymerase (DNA directed), iota0.018
E2f1E2F transcription factor 10.018
Cdc7cell division cycle 7 (S. cerevisiae)0.012
Wdhd1WD repeat and HMG-box DNA binding protein 10.012
PaskPAS domain containing serine/threonine kinase0.012
Clk4CDC like kinase 40.012
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.011
TtkTtk protein kinase0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
RAD5Rad5p0.951
REV1Rev1p0.859
REV7Rev7p0.857
POL2Pol2p0.776
POL3Pol3p0.526
UBC13Ubc13p0.490
POL30Pol30p0.458
MSH6Msh6p0.437
REV3Rev3p0.404
RAD9Rad9p0.385
HTB2Htb2p0.372
PIF1Pif1p0.267
SMC6Smc6p0.240
MSH3Msh3p0.235
RAD18Rad18p0.223
PMS1Pms1p0.217
SHU1Shu1p0.193
RAD1Rad1p0.162
DPB2Dpb2p0.157
POL32Pol32p0.152
RAD17Rad17p0.140
POL12Pol12p0.135
RAD24Rad24p0.133
HTA1Hta1p0.111
CDC9Cdc9p0.108
HTB1Htb1p0.096
RAD30Rad30p0.094
SIZ1Siz1p0.091
MMS21Mms21p0.089
RNH203Rnh203p0.088
NSE4Nse4p0.085
MGS1Mgs1p0.083
HHF2Hhf2p0.082
DUN1Dun1p0.077
MEX67Mex67p0.072
UBA1Uba1p0.071
CSM2Csm2p0.064
RFC2Rfc2p0.057
DPB3Dpb3p0.057
XRS2Xrs2p0.048
HHT2Hht2p0.048
TAF4Taf4p0.047
PAN2Pan2p0.047
ORC6Orc6p0.045
DDC1Ddc1p0.045
RFA3Rfa3p0.043
RAD55Rad55p0.043
SDC1Sdc1p0.041
SRD1Srd1p0.040
TIF4632Tif4632p0.040
NRD1Nrd1p0.040
RAD27Rad27p0.040
HOR2Hor2p0.040
URA3Ura3p0.040
YLR264C-Ahypothetical protein0.039
IBD2Ibd2p0.038
YHR127Whypothetical protein0.038
PBP1Pbp1p0.036
RAD54Rad54p0.036
YOL038C-Ahypothetical protein0.035
DLS1Dls1p0.035
PRS2Prs2p0.035
MER1Mer1p0.035
SEM1Sem1p0.035
MGT1Mgt1p0.034
APN1Apn1p0.034
SMC5Smc5p0.034
CRP1Crp1p0.033
RAD59Rad59p0.033
SLN1Sln1p0.033
LEU2Leu2p0.033
TFG2Tfg2p0.032
YAR068Whypothetical protein0.032
RTT107Rtt107p0.032
YLR162Whypothetical protein0.032
SWC7Swc7p0.032
NTG2Ntg2p0.031
HDA2Hda2p0.031
HXT3Hxt3p0.031
RDH54Rdh54p0.030
EXO1Exo1p0.030
PRE2Pre2p0.029
APN2Apn2p0.029
HOHop0.029
HLR1Hlr1p0.028
WSS1Wss1p0.028
YIR035Chypothetical protein0.028
SHU2Shu2p0.028
RPB11Rpb11p0.027
YLR042Chypothetical protein0.027
ARO9Aro9p0.027
ARP10Arp10p0.026
EST2Est2p0.026
ATP6Atp6p0.026
YBR013Chypothetical protein0.026
SPT5Spt5p0.025
SKG6Skg6p0.025
RAD10Rad10p0.025
CUP1-1Cup1-1p0.025
RPB3Rpb3p0.025