The network for 'regulation of organ formation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of organ formation

Any process that modulates the rate, frequency or extent of organ formation. Organ formation is the process pertaining to the initial formation of an organ from unspecified parts. The process begins with the specific processes that contribute to the appearance of the discrete structure, such as inductive events, and ends when the structural rudiment of the organ is recognizable, such as a condensation of mesenchymal cells into the organ rudiment.

NameDescriptionProbabilityFunc Analog Organism
FGFR1fibroblast growth factor receptor 10.996
DVL1dishevelled, dsh homolog 1 (Drosophila)0.995
FGFR2fibroblast growth factor receptor 20.990
DVL3dishevelled, dsh homolog 3 (Drosophila)0.987
FGF1fibroblast growth factor 1 (acidic)0.976
CSNK1Ecasein kinase 1, epsilon0.969
FOXD3forkhead box D30.956
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.919
BMPR1Abone morphogenetic protein receptor, type IA0.863
SOX10SRY (sex determining region Y)-box 100.827
AXIN1axin 10.782
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.724
LRP6low density lipoprotein receptor-related protein 60.697
NEDD4neural precursor cell expressed, developmentally down-regulated 40.648
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.584
SP1Sp1 transcription factor0.528
APCadenomatous polyposis coli0.502
LRRK2leucine-rich repeat kinase 20.499
JAG1jagged 10.494
TAOK1TAO kinase 10.460
PLCG1phospholipase C, gamma 10.447
NCOA2nuclear receptor coactivator 20.443
CSNK1Dcasein kinase 1, delta0.431
FGF2fibroblast growth factor 2 (basic)0.430
HCFC1host cell factor C1 (VP16-accessory protein)0.419
CTNNBIP1catenin, beta interacting protein 10.370
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.363
CEP164centrosomal protein 164kDa0.310
GATA4GATA binding protein 40.307
SOX2SRY (sex determining region Y)-box 20.269
WT1Wilms tumor 10.261
ZNF512Bzinc finger protein 512B0.260
MYST2MYST histone acetyltransferase 20.253
MDFIMyoD family inhibitor0.239
NOTCH3notch 30.237
BTRCbeta-transducin repeat containing0.219
NR4A1nuclear receptor subfamily 4, group A, member 10.200
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.183
FRS2fibroblast growth factor receptor substrate 20.182
PAX3paired box 30.175
FSTL1follistatin-like 10.172
GLIS2GLIS family zinc finger 20.171
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.151
GSK3Bglycogen synthase kinase 3 beta0.146
TCF4transcription factor 40.146
EP300E1A binding protein p3000.146
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.123
NOSTRINnitric oxide synthase trafficker0.120
PTPN11protein tyrosine phosphatase, non-receptor type 110.116
FOXO1forkhead box O10.115
ZNF205zinc finger protein 2050.110
FAM110Afamily with sequence similarity 110, member A0.103
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.099
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.093
MAML1mastermind-like 1 (Drosophila)0.093
HOXA10homeobox A100.092
FGF7fibroblast growth factor 70.087
PIK3CBphosphoinositide-3-kinase, catalytic, beta polypeptide0.087
HOXD13homeobox D130.084
SOX11SRY (sex determining region Y)-box 110.083
HOXD10homeobox D100.078
SPRY2sprouty homolog 2 (Drosophila)0.074
SMAD7SMAD family member 70.074
FGF8fibroblast growth factor 8 (androgen-induced)0.073
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.069
FZD8frizzled homolog 8 (Drosophila)0.066
MCCmutated in colorectal cancers0.065
FZD1frizzled homolog 1 (Drosophila)0.060
PITX1paired-like homeodomain 10.055
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.054
BAHD1bromo adjacent homology domain containing 10.052
SMAD1SMAD family member 10.051
ZFYVE9zinc finger, FYVE domain containing 90.051
CREBBPCREB binding protein0.050
FAM110Cfamily with sequence similarity 110, member C0.049
FGF3fibroblast growth factor 30.048
HMGA1high mobility group AT-hook 10.048
HOXB9homeobox B90.047
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.047
ATN1atrophin 10.045
C9orf100chromosome 9 open reading frame 1000.045
NOTCH2notch 20.044
LEF1lymphoid enhancer-binding factor 10.044
FGF4fibroblast growth factor 40.043
ERGv-ets erythroblastosis virus E26 oncogene homolog (avian)0.043
SMAD3SMAD family member 30.043
FOXA1forkhead box A10.042
EYA1eyes absent homolog 1 (Drosophila)0.040
FOXE1forkhead box E1 (thyroid transcription factor 2)0.040
GAB1GRB2-associated binding protein 10.039
HOXB5homeobox B50.039
HOXD9homeobox D90.039
SOX1SRY (sex determining region Y)-box 10.038
DLL1delta-like 1 (Drosophila)0.038
FGFR3fibroblast growth factor receptor 30.038
CADM4cell adhesion molecule 40.038
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
cicubitus interruptus0.870
EgfrEpidermal growth factor receptor0.698
eyaeyes absent0.506
sogshort gastrulation0.296
argosCG4531 gene product from transcript CG4531-RA0.275
stumpsCG31317 gene product from transcript CG31317-RC0.262
sosine oculis0.133
grhgrainy head0.128
aopanterior open0.085
salmspalt major0.081
wbwing blister0.072
slp1sloppy paired 10.055
CG8965CG8965 gene product from transcript CG8965-RA0.052
MadMothers against dpp0.049
tsgtwisted gastrulation0.049
DadDaughters against dpp0.044
fz2frizzled 20.036
dallydivision abnormally delayed0.035
abd-Aabdominal A0.035
Lim1CG11354 gene product from transcript CG11354-RA0.032
LanB1CG7123 gene product from transcript CG7123-RA0.030
zfh1Zn finger homeodomain 10.026
vvlventral veins lacking0.026
gcmglial cells missing0.025
nrv2nervana 20.025
Wnt2Wnt oncogene analog 20.022
C15CG7937 gene product from transcript CG7937-RA0.022
Lim3CG10699 gene product from transcript CG10699-RB0.021
NotumCG13076 gene product from transcript CG13076-RB0.020
bowlbrother of odd with entrails limited0.020
opaodd paired0.020
nocno ocelli0.020
MrtfMyocardin-related transcription factor0.019
Traf4TNF-receptor-associated factor 40.019
osaCG7467 gene product from transcript CG7467-RD0.019
LanALaminin A0.019
Mlp84BMuscle LIM protein at 84B0.018
Act42AActin 42A0.018
SaraSmad anchor for receptor activation0.017
HmgcrHMG Coenzyme A reductase0.016
Irk2Inwardly rectifying potassium channel 20.016
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Pitx2paired-like homeodomain transcription factor 21.000
Fgf8fibroblast growth factor 81.000
Otx2orthodenticle homolog 2 (Drosophila)0.999
Pax2paired box gene 20.998
Foxc1forkhead box C10.993
Fgfr3fibroblast growth factor receptor 30.991
Tbx1T-box 10.991
Fgfr2fibroblast growth factor receptor 20.991
Emx2empty spiracles homolog 2 (Drosophila)0.989
Lhx3LIM homeobox protein 30.985
Gli3GLI-Kruppel family member GLI30.983
Lhx1LIM homeobox protein 10.982
Hand2heart and neural crest derivatives expressed transcript 20.977
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.970
Vangl2vang-like 2 (van gogh, Drosophila)0.968
Hoxd11homeobox D110.954
Nr5a1nuclear receptor subfamily 5, group A, member 10.949
Hoxa13homeobox A130.913
Hoxa11homeobox A110.909
Hoxa1homeobox A10.899
Foxc2forkhead box C20.894
Pax3paired box gene 30.878
Wt1Wilms tumor 1 homolog0.863
Ascl1achaete-scute complex homolog 1 (Drosophila)0.847
Ror2receptor tyrosine kinase-like orphan receptor 20.845
Tcfap2atranscription factor AP-2, alpha0.843
Bmp7bone morphogenetic protein 70.830
Pitx1paired-like homeodomain transcription factor 10.787
Pax6paired box gene 60.785
Gli2GLI-Kruppel family member GLI20.761
Gscgoosecoid homeobox0.728
Hand1heart and neural crest derivatives expressed transcript 10.722
Tbx3T-box 30.720
Sox2SRY-box containing gene 20.708
En1engrailed 10.694
Bmp4bone morphogenetic protein 40.653
Kiss1KiSS-1 metastasis-suppressor0.650
Hoxd13homeobox D130.637
Hoxa2homeobox A20.627
Dkk1dickkopf homolog 1 (Xenopus laevis)0.627
Sall4sal-like 4 (Drosophila)0.589
Fgfr1fibroblast growth factor receptor 10.558
Emx1empty spiracles homolog 1 (Drosophila)0.550
Tcf21transcription factor 210.549
Foxh1forkhead box H10.524
Msx2homeobox, msh-like 20.519
Tcf15transcription factor 150.514
Gdnfglial cell line derived neurotrophic factor0.503
Dok1docking protein 10.498
Gata4GATA binding protein 40.488
Wnt3awingless-related MMTV integration site 3A0.455
Pax8paired box gene 80.446
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.430
Gja5gap junction protein, alpha 50.413
Fgf9fibroblast growth factor 90.409
Isl1ISL1 transcription factor, LIM/homeodomain0.385
Tbx2T-box 20.378
Six6sine oculis-related homeobox 6 homolog (Drosophila)0.373
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.369
Lmx1bLIM homeobox transcription factor 1 beta0.366
Prrx2paired related homeobox 20.351
Amhr2anti-Mullerian hormone type 2 receptor0.347
Grb2growth factor receptor bound protein 20.345
Msx1homeobox, msh-like 10.342
Tbx15T-box 150.332
Gata6GATA binding protein 60.330
Ntf3neurotrophin 30.302
Smad6MAD homolog 6 (Drosophila)0.297
Prrx1paired related homeobox 10.285
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.283
Tlx3T-cell leukemia, homeobox 30.280
Otx1orthodenticle homolog 1 (Drosophila)0.280
Neurog1neurogenin 10.278
Foxg1forkhead box G10.274
Gbx2gastrulation brain homeobox 20.273
Snai1snail homolog 1 (Drosophila)0.268
Alx4aristaless-like homeobox 40.267
Fgf15fibroblast growth factor 150.264
Pou3f3POU domain, class 3, transcription factor 30.252
Ptenphosphatase and tensin homolog0.238
Zic3zinc finger protein of the cerebellum 30.236
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.234
Pitx3paired-like homeodomain transcription factor 30.230
Rargretinoic acid receptor, gamma0.224
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.224
Spry4sprouty homolog 4 (Drosophila)0.214
Smosmoothened homolog (Drosophila)0.209
Chd7chromodomain helicase DNA binding protein 70.207
Esrrbestrogen related receptor, beta0.206
Hmx1H6 homeobox 10.205
Foxf2forkhead box F20.202
Pou4f3POU domain, class 4, transcription factor 30.201
Efna2ephrin A20.198
Sox9SRY-box containing gene 90.193
Spry2sprouty homolog 2 (Drosophila)0.191
Sim2single-minded homolog 2 (Drosophila)0.191
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cxxc4CXXC finger 40.310
Unc5bunc-5 homolog B (C. elegans)0.251
P2rx6purinergic receptor P2X, ligand-gated ion channel, 60.143
MrgprfMAS-related GPR, member F0.141
Sox13SRY (sex determining region Y)-box 130.115
Slc9a1solute carrier family 9 (sodium/hydrogen exchanger), member 10.098
Gtf2a1general transcription factor IIA, 10.091
Fgf5fibroblast growth factor 50.087
Cdkn2bcyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)0.085
Prap1proline-rich acidic protein 10.074
Chrnb3cholinergic receptor, nicotinic, beta 30.070
Myo1cmyosin IC0.067
Olr1867olfactory receptor 18670.067
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.066
Tgfbr3transforming growth factor, beta receptor III0.065
Nfibnuclear factor I/B0.064
Syt9synaptotagmin IX0.062
RGD1309821similar to KIAA1161 protein0.062
Mcammelanoma cell adhesion molecule0.061
Hsf4heat shock transcription factor 40.060
Olfml2bolfactomedin-like 2B0.059
Nr2f2nuclear receptor subfamily 2, group F, member 20.058
Kykyphoscoliosis peptidase0.058
Gfra2GDNF family receptor alpha 20.057
Akt1v-akt murine thymoma viral oncogene homolog 10.056
Adrb1adrenergic, beta-1-, receptor0.056
Myh9myosin, heavy chain 9, non-muscle0.056
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.056
Kcng2potassium voltage-gated channel, subfamily G, member 20.056
Masp1mannan-binding lectin serine peptidase 10.055
Foxc2forkhead box C20.055
Irs1insulin receptor substrate 10.053
Phkg1phosphorylase kinase, gamma 10.052
Ppardperoxisome proliferator-activated receptor delta0.052
Glg1golgi apparatus protein 10.052
Tnni1troponin I type 1 (skeletal, slow)0.052
Ebf1early B-cell factor 10.051
Gja3gap junction protein, alpha 30.051
Tas2r119taste receptor, type 2, member 1190.051
Pde3aphosphodiesterase 3A, cGMP inhibited0.049
Slc6a18solute carrier family 6, member 180.049
GperG protein-coupled estrogen receptor 10.048
Fgf18fibroblast growth factor 180.048
Slc13a1solute carrier family 13 (sodium/sulfate symporters), member 10.048
Cst12cystatin 120.047
Itpr2inositol 1,4,5-triphosphate receptor, type 20.046
Nr5a2nuclear receptor subfamily 5, group A, member 20.045
Pga5pepsinogen 5, group I0.045
A2bp1ataxin 2 binding protein 10.045
Smad7SMAD family member 70.044
Cacng4calcium channel, voltage-dependent, gamma subunit 40.043
F13a1coagulation factor XIII, A1 polypeptide0.043
Ednraendothelin receptor type A0.042
Ccdc102acoiled-coil domain containing 102A0.041
Acvr1activin A receptor, type I0.040
Lamc1laminin, gamma 10.040
Znf503zinc finger protein 5030.040
Gdnfglial cell derived neurotrophic factor0.040
Bdkrb2bradykinin receptor B20.040
Sod3superoxide dismutase 3, extracellular0.039
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.038
Cacng7calcium channel, voltage-dependent, gamma subunit 70.037
Adamts13ADAM metallopeptidase with thrombospondin type 1 motif, 130.037
Hcn3hyperpolarization-activated cyclic nucleotide-gated potassium channel 30.036
Paqr8progestin and adipoQ receptor family member VIII0.036
Vegp1von Ebners gland protein 10.035
Trim66tripartite motif-containing 660.035
Prok1prokineticin 10.035
Tgfb2transforming growth factor, beta 20.034
Syt8synaptotagmin VIII0.034
Prokr1prokineticin receptor 10.034
Kcnv1potassium channel, subfamily V, member 10.034
siat7Dalpha-2,6-sialyltransferase ST6GalNAc IV0.033
Hist1h4mhistone cluster 1, H4m0.033
Cdh6cadherin 60.033
Stk11serine/threonine kinase 110.033
Slc22a2solute carrier family 22 (organic cation transporter), member 20.033
Madcam1mucosal vascular addressin cell adhesion molecule 10.032
Hoxb7homeo box B70.032
Stx2syntaxin 20.031
Ucn2urocortin 20.031
Cpxm2carboxypeptidase X (M14 family), member 20.031
Hoxd9homeo box D90.031
Map3k3mitogen activated protein kinase kinase kinase 30.030
Pth2rparathyroid hormone 2 receptor0.030
Foxs1forkhead box S10.030
Mybphlmyosin binding protein H-like0.030
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.029
Ltbp3latent transforming growth factor beta binding protein 30.029
Robo1roundabout homolog 1 (Drosophila)0.029
Tead3TEA domain family member 30.029
Npr3natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)0.029
Dbhdopamine beta-hydroxylase (dopamine beta-monooxygenase)0.029
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.029
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism