The network for 'apoptotic dna fragmentation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

apoptotic dna fragmentation

The cleavage of DNA during apoptosis, which usually occurs in two stages: cleavage into fragments of about 50 kbp followed by cleavage between nucleosomes to yield 200 bp fragments.

NameDescriptionProbabilityFunc Analog Organism
BCL2B-cell CLL/lymphoma 20.997
BCL2L1BCL2-like 10.989
CASP9caspase 9, apoptosis-related cysteine peptidase0.450
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.432
BAXBCL2-associated X protein0.415
EXOSC7exosome component 70.301
CASP3caspase 3, apoptosis-related cysteine peptidase0.215
EXOSC3exosome component 30.180
BCL2L11BCL2-like 11 (apoptosis facilitator)0.178
BAK1BCL2-antagonist/killer 10.089
POU5F1POU class 5 homeobox 10.078
EXOSC1exosome component 10.072
XIAPX-linked inhibitor of apoptosis0.043
BIDBH3 interacting domain death agonist0.041
APAF1apoptotic peptidase activating factor 10.039
XAB2XPA binding protein 20.022
C4orf14chromosome 4 open reading frame 140.019
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.019
DIS3DIS3 mitotic control homolog (S. cerevisiae)0.017
HUWE1HECT, UBA and WWE domain containing 10.016
EXOSC2exosome component 20.015
TNRC6Atrinucleotide repeat containing 6A0.014
EIF2C1eukaryotic translation initiation factor 2C, 10.013
BECN1beclin 1, autophagy related0.013
DIS3LDIS3 mitotic control homolog (S. cerevisiae)-like0.011
BADBCL2-associated agonist of cell death0.011
VDAC1voltage-dependent anion channel 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
exo-1Protein EXO-10.017
CELE_F43D2.1Protein F43D2.10.017
F58B3.7Protein F58B3.70.014
C06A8.2Protein C06A8.20.014
K11B4.2Protein K11B4.20.012
CELE_C24D10.6Protein C24D10.60.012
Y5F2A.4Protein Y5F2A.40.012
rbg-3Protein RBG-30.012
CELE_M05D6.2Protein M05D6.20.011
mage-1Protein MAGE-10.011
dnj-23Protein DNJ-230.011
B0511.7Protein B0511.70.011
cutc-1Protein CUTC-10.010
CELE_F55H2.7Protein F55H2.70.010
mrpl-51Protein MRPL-510.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Casp1caspase 10.884
Casp4caspase 4, apoptosis-related cysteine peptidase0.865
Aim2absent in melanoma 20.734
Gbp5guanylate binding protein 50.666
PycardPYD and CARD domain containing0.480
Plin1perilipin 10.443
Il18interleukin 180.283
Tlr4toll-like receptor 40.216
DffbDNA fragmentation factor, beta subunit0.208
Apaf1apoptotic peptidase activating factor 10.078
Il1binterleukin 1 beta0.057
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.056
Il1r1interleukin 1 receptor, type I0.054
Rbl1retinoblastoma-like 1 (p107)0.053
Atrataxia telangiectasia and Rad3 related0.052
Cideccell death-inducing DFFA-like effector c0.050
Bak1BCL2-antagonist/killer 10.042
Nlrp3NLR family, pyrin domain containing 30.040
Bcl2B-cell leukemia/lymphoma 20.037
Lbrlamin B receptor0.034
Stat1signal transducer and activator of transcription 10.033
Cfdcomplement factor D (adipsin)0.033
Hhathedgehog acyltransferase0.027
Kitkit oncogene0.027
Cideacell death-inducing DNA fragmentation factor, alpha subunit-like effector A0.025
Lyz2lysozyme 20.025
Rb1retinoblastoma 10.025
Prkab1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.024
Cox5acytochrome c oxidase, subunit Va0.024
Mcm7minichromosome maintenance deficient 7 (S. cerevisiae)0.023
FasFas (TNF receptor superfamily member 6)0.022
Uqcrc2ubiquinol cytochrome c reductase core protein 20.022
BidBH3 interacting domain death agonist0.022
Adam10a disintegrin and metallopeptidase domain 100.020
Trp53transformation related protein 530.020
Ndufab1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 10.018
Mobkl1bMOB1, Mps One Binder kinase activator-like 1B (yeast)0.018
Birc3baculoviral IAP repeat-containing 30.018
Lystlysosomal trafficking regulator0.018
Foxp3forkhead box P30.017
Retnresistin0.017
Plin4perilipin 40.017
Cdk4cyclin-dependent kinase 40.016
Gbp7guanylate binding protein 70.016
Ndufaf4NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 40.015
Ctnnb1catenin (cadherin associated protein), beta 10.015
Gbp3guanylate binding protein 30.014
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.014
Gcshglycine cleavage system protein H (aminomethyl carrier)0.014
Ighimmunoglobulin heavy chain complex0.014
Dckdeoxycytidine kinase0.014
Ikbkbinhibitor of kappaB kinase beta0.013
Safbscaffold attachment factor B0.013
Mrpl18mitochondrial ribosomal protein L180.013
FaddFas (TNFRSF6)-associated via death domain0.013
Casp7caspase 70.012
Ndufa12NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 120.012
NansN-acetylneuraminic acid synthase (sialic acid synthase)0.012
Tfamtranscription factor A, mitochondrial0.012
Adigadipogenin0.011
Pola1polymerase (DNA directed), alpha 10.011
Atmataxia telangiectasia mutated homolog (human)0.011
Ints7integrator complex subunit 70.010
Mlh1mutL homolog 1 (E. coli)0.010
Ripk3receptor-interacting serine-threonine kinase 30.010
Ccr1chemokine (C-C motif) receptor 10.010
Mcm4minichromosome maintenance deficient 4 homolog (S. cerevisiae)0.010
Droshadrosha, ribonuclease type III0.010
Casp8caspase 80.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism