The network for 'fat cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

fat cell differentiation

The process in which a relatively unspecialized cell acquires specialized features of an adipocyte, an animal connective tissue cell specialized for the synthesis and storage of fat.

NameDescriptionProbabilityFunc Analog Organism
BBS10Bardet-Biedl syndrome 100.982
SMAD3SMAD family member 30.906
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.844
EP300E1A binding protein p3000.785
TP53tumor protein p530.702
C1QAcomplement component 1, q subcomponent, A chain0.678
SMAD7SMAD family member 70.602
GSK3Bglycogen synthase kinase 3 beta0.601
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.587
AKT1v-akt murine thymoma viral oncogene homolog 10.537
PDIA3protein disulfide isomerase family A, member 30.522
SMAD4SMAD family member 40.514
ARandrogen receptor0.497
SMURF2SMAD specific E3 ubiquitin protein ligase 20.488
PTK2PTK2 protein tyrosine kinase 20.408
BBS4Bardet-Biedl syndrome 40.390
IRAK2interleukin-1 receptor-associated kinase 20.380
CREBBPCREB binding protein0.337
NCOA3nuclear receptor coactivator 30.334
SMAD1SMAD family member 10.321
NR0B1nuclear receptor subfamily 0, group B, member 10.314
TAL1T-cell acute lymphocytic leukemia 10.270
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.264
STK3serine/threonine kinase 30.257
APPamyloid beta (A4) precursor protein0.232
BBS2Bardet-Biedl syndrome 20.226
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.224
ATXN1ataxin 10.220
NCOR1nuclear receptor corepressor 10.218
SP1Sp1 transcription factor0.211
PGRprogesterone receptor0.210
STAG2stromal antigen 20.201
BBS9Bardet-Biedl syndrome 90.173
TGIF1TGFB-induced factor homeobox 10.170
NCF1neutrophil cytosolic factor 10.169
CSNK1Ecasein kinase 1, epsilon0.167
C1QCcomplement component 1, q subcomponent, C chain0.159
NOTCH3notch 30.155
WNT3Awingless-type MMTV integration site family, member 3A0.142
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.125
BBS7Bardet-Biedl syndrome 70.120
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.114
BMPR1Abone morphogenetic protein receptor, type IA0.110
STK4serine/threonine kinase 40.108
SQSTM1sequestosome 10.106
JUNjun proto-oncogene0.105
CDK6cyclin-dependent kinase 60.093
DHCR77-dehydrocholesterol reductase0.090
GATA2GATA binding protein 20.088
AXIN1axin 10.087
APCadenomatous polyposis coli0.084
IRF2BP1interferon regulatory factor 2 binding protein 10.081
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.076
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.070
ZFPM1zinc finger protein, multitype 10.068
SFRP1secreted frizzled-related protein 10.067
HMGA1high mobility group AT-hook 10.067
LRP6low density lipoprotein receptor-related protein 60.067
PRKCZprotein kinase C, zeta0.066
SREBF2sterol regulatory element binding transcription factor 20.064
FSTL1follistatin-like 10.061
SMAD5SMAD family member 50.060
P4HBprolyl 4-hydroxylase, beta polypeptide0.059
EGR1early growth response 10.058
NOXA1NADPH oxidase activator 10.057
PTNpleiotrophin0.056
GLIS2GLIS family zinc finger 20.055
PRKCAprotein kinase C, alpha0.055
C1QBcomplement component 1, q subcomponent, B chain0.050
TCF4transcription factor 40.050
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.050
TBL1XR1transducin (beta)-like 1 X-linked receptor 10.050
IRS1insulin receptor substrate 10.049
SKIv-ski sarcoma viral oncogene homolog (avian)0.048
FZD7frizzled homolog 7 (Drosophila)0.047
ACACAacetyl-CoA carboxylase alpha0.047
NEDD9neural precursor cell expressed, developmentally down-regulated 90.047
ARHGAP5Rho GTPase activating protein 50.045
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.045
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.043
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.042
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.039
FOXO3forkhead box O30.039
EPAS1endothelial PAS domain protein 10.038
CDC14BCDC14 cell division cycle 14 homolog B (S. cerevisiae)0.038
ZNF148zinc finger protein 1480.037
KCTD1potassium channel tetramerisation domain containing 10.036
IQGAP1IQ motif containing GTPase activating protein 10.036
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.036
ZHX1zinc fingers and homeoboxes 10.036
NR4A1nuclear receptor subfamily 4, group A, member 10.036
SAV1salvador homolog 1 (Drosophila)0.035
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.035
RASSF3Ras association (RalGDS/AF-6) domain family member 30.035
HIC1hypermethylated in cancer 10.034
PPARAperoxisome proliferator-activated receptor alpha0.034
SLX1BSLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)0.034
CLOCKclock homolog (mouse)0.034
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.034
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.033
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog0.981
Leprleptin receptor0.981
Gli3GLI-Kruppel family member GLI30.972
Fgfr2fibroblast growth factor receptor 20.966
Bbs2Bardet-Biedl syndrome 2 (human)0.962
Cdkn1bcyclin-dependent kinase inhibitor 1B0.961
JunJun oncogene0.960
Rxraretinoid X receptor alpha0.946
Hes1hairy and enhancer of split 1 (Drosophila)0.938
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.932
Fgf10fibroblast growth factor 100.931
Lef1lymphoid enhancer binding factor 10.925
Bbs4Bardet-Biedl syndrome 4 (human)0.913
Mapk14mitogen-activated protein kinase 140.905
Ppargperoxisome proliferator activated receptor gamma0.903
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.898
Per2period homolog 2 (Drosophila)0.883
Emx2empty spiracles homolog 2 (Drosophila)0.882
FosFBJ osteosarcoma oncogene0.872
Dusp1dual specificity phosphatase 10.870
Pthlhparathyroid hormone-like peptide0.855
Dll1delta-like 1 (Drosophila)0.839
Gli2GLI-Kruppel family member GLI20.838
Klf4Kruppel-like factor 4 (gut)0.828
Clockcircadian locomotor output cycles kaput0.827
Hoxd13homeobox D130.827
Nos3nitric oxide synthase 3, endothelial cell0.820
Ror2receptor tyrosine kinase-like orphan receptor 20.802
Wnt5awingless-related MMTV integration site 5A0.800
Msx1homeobox, msh-like 10.782
Ctnnb1catenin (cadherin associated protein), beta 10.777
Alx4aristaless-like homeobox 40.775
Sfrp2secreted frizzled-related protein 20.770
Hoxa13homeobox A130.769
Snai1snail homolog 1 (Drosophila)0.769
Smad3MAD homolog 3 (Drosophila)0.764
Rargretinoic acid receptor, gamma0.759
Twist2twist homolog 2 (Drosophila)0.753
Smad7MAD homolog 7 (Drosophila)0.751
Thrathyroid hormone receptor alpha0.743
Tcf4transcription factor 40.736
Sox2SRY-box containing gene 20.733
Notch1Notch gene homolog 1 (Drosophila)0.726
Foxf1aforkhead box F1a0.723
Tcf21transcription factor 210.720
Hrhairless0.716
Crb2crumbs homolog 2 (Drosophila)0.714
Plin1perilipin 10.707
Prrx2paired related homeobox 20.699
Nf1neurofibromatosis 10.696
Timp2tissue inhibitor of metalloproteinase 20.691
Btbd17BTB (POZ) domain containing 170.687
Nognoggin0.685
Zeb1zinc finger E-box binding homeobox 10.684
Cideccell death-inducing DFFA-like effector c0.684
Hic1hypermethylated in cancer 10.681
Cdk4cyclin-dependent kinase 40.676
Trp63transformation related protein 630.675
Insrinsulin receptor0.674
Vegfavascular endothelial growth factor A0.671
Acvrl1activin A receptor, type II-like 10.667
Arntlaryl hydrocarbon receptor nuclear translocator-like0.657
Egr1early growth response 10.652
Tbx3T-box 30.648
Prrx1paired related homeobox 10.647
Axin2axin20.633
Msx2homeobox, msh-like 20.630
Btg2B-cell translocation gene 2, anti-proliferative0.627
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.626
Cry2cryptochrome 2 (photolyase-like)0.625
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.624
Smad6MAD homolog 6 (Drosophila)0.623
Pax3paired box gene 30.618
Tal1T-cell acute lymphocytic leukemia 10.607
Pnpla2patatin-like phospholipase domain containing 20.602
Ror1receptor tyrosine kinase-like orphan receptor 10.598
Mmp2matrix metallopeptidase 20.598
Rhobras homolog gene family, member B0.592
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.591
Atf2activating transcription factor 20.588
Ahraryl-hydrocarbon receptor0.587
Apaf1apoptotic peptidase activating factor 10.584
Pax2paired box gene 20.584
Bmp4bone morphogenetic protein 40.582
C1qccomplement component 1, q subcomponent, C chain0.570
Tead3TEA domain family member 30.570
Id3inhibitor of DNA binding 30.565
Tenc1tensin like C1 domain-containing phosphatase0.549
Gdf5growth differentiation factor 50.548
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.536
Gata4GATA binding protein 40.533
Ascl1achaete-scute complex homolog 1 (Drosophila)0.529
Hand1heart and neural crest derivatives expressed transcript 10.529
Nr4a1nuclear receptor subfamily 4, group A, member 10.528
Col2a1collagen, type II, alpha 10.527
Yap1yes-associated protein 10.522
Klf2Kruppel-like factor 2 (lung)0.521
Pitx1paired-like homeodomain transcription factor 10.517
Pax8paired box gene 80.512
Fgf5fibroblast growth factor 50.510
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism