The network for 'regulation of leukocyte migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of leukocyte migration

Any process that modulates the frequency, rate, or extent of leukocyte migration.

NameDescriptionProbabilityFunc Analog Organism
CCR5chemokine (C-C motif) receptor 50.993
IL8interleukin 80.990
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.989
CCL5chemokine (C-C motif) ligand 50.983
S100A6S100 calcium binding protein A60.973
CXCL9chemokine (C-X-C motif) ligand 90.973
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.964
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.960
CXCL10chemokine (C-X-C motif) ligand 100.951
VEGFAvascular endothelial growth factor A0.945
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.940
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.927
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.916
S100BS100 calcium binding protein B0.910
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.906
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.906
PLAUplasminogen activator, urokinase0.889
PLAURplasminogen activator, urokinase receptor0.887
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.887
CXCL3chemokine (C-X-C motif) ligand 30.876
HOXB5homeobox B50.876
S100A16S100 calcium binding protein A160.857
IL1Binterleukin 1, beta0.831
CCL19chemokine (C-C motif) ligand 190.817
CCL4chemokine (C-C motif) ligand 40.813
CXCL2chemokine (C-X-C motif) ligand 20.805
CCL20chemokine (C-C motif) ligand 200.801
IL2RBinterleukin 2 receptor, beta0.766
CD44CD44 molecule (Indian blood group)0.764
CCR1chemokine (C-C motif) receptor 10.761
S100A1S100 calcium binding protein A10.760
CCL2chemokine (C-C motif) ligand 20.749
TIMP1TIMP metallopeptidase inhibitor 10.748
HCKhemopoietic cell kinase0.739
CD163CD163 molecule0.739
MDM2Mdm2 p53 binding protein homolog (mouse)0.734
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.717
S100A14S100 calcium binding protein A140.708
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.702
IL6interleukin 6 (interferon, beta 2)0.701
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.658
EZRezrin0.654
CCL8chemokine (C-C motif) ligand 80.635
APOEapolipoprotein E0.624
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.609
THBS1thrombospondin 10.599
CCL7chemokine (C-C motif) ligand 70.596
COL1A1collagen, type I, alpha 10.576
AXLAXL receptor tyrosine kinase0.572
IL10interleukin 100.558
CCR7chemokine (C-C motif) receptor 70.539
FYNFYN oncogene related to SRC, FGR, YES0.536
EMP3epithelial membrane protein 30.534
LAIR1leukocyte-associated immunoglobulin-like receptor 10.525
IFNGinterferon, gamma0.518
ABI2abl-interactor 20.510
NRP1neuropilin 10.500
PTGIRprostaglandin I2 (prostacyclin) receptor (IP)0.495
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.490
TNFtumor necrosis factor0.485
CCL18chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)0.484
DPP4dipeptidyl-peptidase 40.474
CCL13chemokine (C-C motif) ligand 130.467
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.462
PLEKpleckstrin0.439
VCAM1vascular cell adhesion molecule 10.437
BIRC3baculoviral IAP repeat containing 30.429
GNAI2guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 20.428
CXCL5chemokine (C-X-C motif) ligand 50.426
CXCR4chemokine (C-X-C motif) receptor 40.400
ICAM1intercellular adhesion molecule 10.400
MEFVMediterranean fever0.391
SELPLGselectin P ligand0.381
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.363
CXCL11chemokine (C-X-C motif) ligand 110.358
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.356
CXCL13chemokine (C-X-C motif) ligand 130.345
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.343
PLATplasminogen activator, tissue0.341
S100A11S100 calcium binding protein A110.338
SCHIP1schwannomin interacting protein 10.338
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.332
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.331
FN1fibronectin 10.320
FCN1ficolin (collagen/fibrinogen domain containing) 10.318
TFF1trefoil factor 10.317
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.305
MMP12matrix metallopeptidase 12 (macrophage elastase)0.302
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.289
C5AR1complement component 5a receptor 10.285
RHOCras homolog gene family, member C0.280
TBXA2Rthromboxane A2 receptor0.277
SH3BGRL3SH3 domain binding glutamic acid-rich protein like 30.271
IL2RGinterleukin 2 receptor, gamma0.259
CFHcomplement factor H0.253
HOXA7homeobox A70.251
PDCD6IPprogrammed cell death 6 interacting protein0.250
AQP9aquaporin 90.250
SELLselectin L0.250
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.247
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.968
nod1nucleotide-binding oligomerization domain containing 10.157
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.095
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.086
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.086
lyzlysozyme0.076
ptprsaprotein tyrosine phosphatase, receptor type, s, a0.076
tie2endothelium-specific receptor tyrosine kinase 20.063
card9caspase recruitment domain family, member 90.063
arhgef7bRho guanine nucleotide exchange factor (GEF) 7b0.053
ergv-ets erythroblastosis virus E26 oncogene like (avian)0.053
efnb2aephrin B2a0.051
ptpn6protein tyrosine phosphatase, non-receptor type 60.050
cdh5cadherin 50.045
ptger2aprostaglandin E receptor 2a (subtype EP2)0.044
mmp9matrix metalloproteinase 90.043
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.038
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.038
mmp2matrix metalloproteinase 20.037
si:dkey-236e20.2si:dkey-236e20.20.033
ets1av-ets erythroblastosis virus E26 oncogene homolog 1a0.030
col12a1collagen, type XII, alpha 10.030
st8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.030
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.030
zgc:101614zgc:1016140.029
vegfcvascular endothelial growth factor c0.029
pak2ap21 (CDKN1A)-activated kinase 2a0.027
postnperiostin, osteoblast specific factor0.027
ctsccathepsin C0.026
coro1acoronin, actin binding protein, 1A0.025
btkBruton agammaglobulinemia tyrosine kinase0.025
si:ch211-212m21.5si:ch211-212m21.50.025
lta4hleukotriene A4 hydrolase0.025
nrp2bneuropilin 2b0.024
col6a3collagen, type VI, alpha 30.023
dopey1dopey family member 10.023
plxnd1plexin D10.023
ntlano tail a0.023
ptprcprotein tyrosine phosphatase, receptor type, C0.022
mmp13amatrix metalloproteinase 13a0.022
dll4delta-like 4 (Drosophila)0.021
dzip1DAZ interacting protein 10.021
runx3runt-related transcription factor 30.020
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.019
agtr2angiotensin II receptor, type 20.019
atp6ap1ATPase, H+ transporting, lysosomal accessory protein 10.019
irf8interferon regulatory factor 80.018
ncf1neutrophil cytosolic factor 10.018
cbfbcore-binding factor, beta subunit0.018
im:7154036im:71540360.017
tpm4tropomyosin 40.017
tll1tolloid-like 10.017
si:ch211-235f6.2si:ch211-235f6.20.017
meox1mesenchyme homeobox 10.017
kitlgakit ligand a0.017
epas1bendothelial PAS domain protein 1b0.016
hspg2heparan sulfate proteoglycan 20.016
col5a1procollagen, type V, alpha 10.016
rhagRhesus blood group-associated glycoprotein0.016
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.016
clic2chloride intracellular channel 20.015
esamaendothelial cell adhesion molecule a0.015
ccbe1collagen and calcium binding EGF domains 10.015
jam2ajunctional adhesion molecule 2a0.015
zgc:110010zgc:1100100.014
igfbp3insulin-like growth factor binding protein 30.014
cdc42lcell division cycle 42, like0.014
lgals3bpblectin, galactoside-binding, soluble, 3 binding protein b0.014
si:dkey-261h17.1si:dkey-261h17.10.013
sp2sp2 transcription factor0.013
flncbfilamin C, gamma b (actin binding protein 280)0.013
tnfsf18tumor necrosis factor (ligand) superfamily, member 180.013
ints6integrator complex subunit 60.013
htra1aHtrA serine peptidase 1a0.012
sla1Src-like-adaptor 10.012
ccr6achemokine (C-C motif) receptor 6a0.012
clstn1calsyntenin 10.012
gmfgglia maturation factor, gamma0.012
si:dkeyp-104h9.6si:dkeyp-104h9.60.012
wu:fj39b01wu:fj39b010.012
gnb1aguanine nucleotide binding protein (G protein), beta polypeptide 1a0.012
six1bsine oculis homeobox homolog 1b0.011
ephb4aeph receptor B4a0.011
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.011
gpr182G protein-coupled receptor 1820.011
spred1sprouty-related, EVH1 domain containing 10.011
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.011
myd88myeloid differentiation primary response gene (88)0.011
mpxmyeloid-specific peroxidase0.011
adora2aaadenosine A2a receptor a0.010
ccl25bchemokine (C-C motif) ligand 25b0.010
dlcdeltaC0.010
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.010
si:dkey-12o15.1si:dkey-12o15.10.010
hnf1aHNF1 homeobox a0.010
ftsjFtsJ homolog 3 (E. coli)0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cxcl10chemokine (C-X-C motif) ligand 100.942
Ccl4chemokine (C-C motif) ligand 40.894
Il1binterleukin 1 beta0.741
Cd4Cd4 molecule0.690
Mmp3matrix metallopeptidase 30.689
Ccl2chemokine (C-C motif) ligand 20.654
Slco2b1solute carrier organic anion transporter family, member 2b10.628
Olr1500olfactory receptor 15000.624
Cxcl2chemokine (C-X-C motif) ligand 20.603
Il6interleukin 60.459
Thbdthrombomodulin0.400
RT1-BaRT1 class II, locus Ba0.380
Mmp10matrix metallopeptidase 100.375
Ccl3chemokine (C-C motif) ligand 30.365
Il8rbinterleukin 8 receptor, beta0.342
Il1rninterleukin 1 receptor antagonist0.336
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.325
Plauplasminogen activator, urokinase0.298
Neurl3neuralized homolog 3 (Drosophila)0.262
Cd14CD14 molecule0.261
Fosl1fos-like antigen 10.253
Hckhemopoietic cell kinase0.248
Il1ainterleukin 1 alpha0.237
Adam2ADAM metallopeptidase domain 20.234
Ptafrplatelet-activating factor receptor0.230
Calcrlcalcitonin receptor-like0.215
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.210
F2rl1coagulation factor II (thrombin) receptor-like 10.206
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.188
Kcnj8potassium inwardly-rectifying channel, subfamily J, member 80.170
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.148
Icam1intercellular adhesion molecule 10.146
P2ry14purinergic receptor P2Y, G-protein coupled, 140.145
Tnftumor necrosis factor (TNF superfamily, member 2)0.143
RT1-DaRT1 class II, locus Da0.138
Reg3gregenerating islet-derived 3 gamma0.136
Klrd1killer cell lectin-like receptor, subfamily D, member 10.134
Casp1caspase 10.134
Cd44Cd44 molecule0.133
Ptprcprotein tyrosine phosphatase, receptor type, C0.132
Reg3bregenerating islet-derived 3 beta0.129
Gzmbgranzyme B0.118
Cxcr4chemokine (C-X-C motif) receptor 40.114
Myo1cmyosin IC0.114
Ctsjcathepsin J0.114
Fgf2fibroblast growth factor 20.113
Ccl20chemokine (C-C motif) ligand 200.112
Olfml2bolfactomedin-like 2B0.110
Mmp12matrix metallopeptidase 120.108
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.107
Sellselectin L0.106
Ccl11chemokine (C-C motif) ligand 110.104
RT1-BbRT1 class II, locus Bb0.101
Cd8aCD8a molecule0.098
FaslgFas ligand (TNF superfamily, member 6)0.098
Laptm5lysosomal protein transmembrane 50.093
TcrbT-cell receptor beta chain0.092
Leprleptin receptor0.087
Olr1078olfactory receptor 10780.087
Socs3suppressor of cytokine signaling 30.085
Adora2aadenosine A2a receptor0.082
Utrnutrophin0.080
Col12a1collagen, type XII, alpha 10.079
Slc30a2solute carrier family 30 (zinc transporter), member 20.076
Crisp1cysteine-rich secretory protein 10.075
Il2rginterleukin 2 receptor, gamma0.075
MrgprfMAS-related GPR, member F0.072
LOC100360403ATP-binding cassette, sub-family C, member 9-like0.066
Ccl7chemokine (C-C motif) ligand 70.065
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.063
Pthparathyroid hormone0.060
Vipvasoactive intestinal peptide0.060
Gzmkgranzyme K0.060
Egr2early growth response 20.060
Kcna3potassium voltage-gated channel, shaker-related subfamily, member 30.059
Arandrogen receptor0.059
Mmp2matrix metallopeptidase 20.058
Il1r2interleukin 1 receptor, type II0.058
Ankrd1ankyrin repeat domain 1 (cardiac muscle)0.058
Ccl5chemokine (C-C motif) ligand 50.057
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.057
S1pr2sphingosine-1-phosphate receptor 20.055
Cybbcytochrome b-245, beta polypeptide0.055
Psmd8proteasome (prosome, macropain) 26S subunit, non-ATPase, 80.054
Dnase1l3deoxyribonuclease 1-like 30.053
LOC100364854similar to RIKEN cDNA A430107P09 gene-like0.051
Slc5a1solute carrier family 5 (sodium/glucose cotransporter), member 10.051
Figfc-fos induced growth factor0.050
Avpr1barginine vasopressin receptor 1B0.050
Sycp1synaptonemal complex protein 10.049
LOC100364485mCG1051031-like0.049
Clic4chloride intracellular channel 40.049
Vcanversican0.049
Ier3immediate early response 30.048
Igsf6immunoglobulin superfamily, member 60.048
Phexphosphate regulating endopeptidase homolog, X-linked0.047
Il9rinterleukin 9 receptor0.047
Ednraendothelin receptor type A0.046
Atxn1ataxin 10.045
Atf3activating transcription factor 30.045
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism