The network for 'negative regulation of carbohydrate metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of carbohydrate metabolic process

Any process that stops, prevents, or reduces the frequency, rate or extent of the chemical reactions and pathways involving carbohydrate.

NameDescriptionProbabilityFunc Analog Organism
UGT1A3UDP glucuronosyltransferase 1 family, polypeptide A30.324
SHC1SHC (Src homology 2 domain containing) transforming protein 10.260
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.173
IRS1insulin receptor substrate 10.147
INSRinsulin receptor0.139
OGTO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)0.134
HIP1huntingtin interacting protein 10.124
ZNF746zinc finger protein 7460.074
TERF2telomeric repeat binding factor 20.072
IGF1Rinsulin-like growth factor 1 receptor0.070
ITGB1BP3integrin beta 1 binding protein 30.063
ARID4BAT rich interactive domain 4B (RBP1-like)0.044
MDM2Mdm2 p53 binding protein homolog (mouse)0.041
RAB6ARAB6A, member RAS oncogene family0.040
PPARGperoxisome proliferator-activated receptor gamma0.039
FUNDC2FUN14 domain containing 20.039
NUMBnumb homolog (Drosophila)0.037
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.037
SH2B1SH2B adaptor protein 10.033
TERF2IPtelomeric repeat binding factor 2, interacting protein0.032
KIF5Bkinesin family member 5B0.031
ESRRGestrogen-related receptor gamma0.027
IRS2insulin receptor substrate 20.025
OCRLoculocerebrorenal syndrome of Lowe0.024
RNF103ring finger protein 1030.022
HNF4Ahepatocyte nuclear factor 4, alpha0.022
BCL3B-cell CLL/lymphoma 30.021
RAB5ARAB5A, member RAS oncogene family0.021
UGT1A9UDP glucuronosyltransferase 1 family, polypeptide A90.020
LNX1ligand of numb-protein X 10.020
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.018
PINK1PTEN induced putative kinase 10.017
OSBPoxysterol binding protein0.016
HMOX2heme oxygenase (decycling) 20.016
ACDadrenocortical dysplasia homolog (mouse)0.016
TGFB3transforming growth factor, beta 30.016
PTPN1protein tyrosine phosphatase, non-receptor type 10.015
CLK3CDC-like kinase 30.014
CAPN1calpain 1, (mu/I) large subunit0.014
RAB14RAB14, member RAS oncogene family0.014
MYBv-myb myeloblastosis viral oncogene homolog (avian)0.014
VEGFAvascular endothelial growth factor A0.014
MEF2Amyocyte enhancer factor 2A0.013
TERF1telomeric repeat binding factor (NIMA-interacting) 10.012
THBS1thrombospondin 10.012
TOM1L1target of myb1 (chicken)-like 10.012
HDAC6histone deacetylase 60.012
IGF2Rinsulin-like growth factor 2 receptor0.012
ATXN3ataxin 30.012
RAB1ARAB1A, member RAS oncogene family0.011
IER2immediate early response 20.011
PDCD2programmed cell death 20.011
RBM5RNA binding motif protein 50.011
GCKRglucokinase (hexokinase 4) regulator0.010
APPamyloid beta (A4) precursor protein0.010
PTPN11protein tyrosine phosphatase, non-receptor type 110.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Mef2dmyocyte enhancer factor 2D0.880
Ppargperoxisome proliferator activated receptor gamma0.768
C1qccomplement component 1, q subcomponent, C chain0.736
C1qacomplement component 1, q subcomponent, alpha polypeptide0.596
Leprleptin receptor0.596
Insrinsulin receptor0.587
LOC100048884novel member of the major urinary protein (Mup) gene family0.443
Lepleptin0.440
Socs1suppressor of cytokine signaling 10.434
Mup10major urinary protein 100.317
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.314
Clk1CDC-like kinase 10.313
Lyz2lysozyme 20.310
Ccnl2cyclin L20.303
Foxc1forkhead box C10.282
Mup19major urinary protein 190.265
C1qbcomplement component 1, q subcomponent, beta polypeptide0.249
Irf9interferon regulatory factor 90.208
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.201
Prlrprolactin receptor0.177
Pim3proviral integration site 30.172
Foxa2forkhead box A20.155
Stat5bsignal transducer and activator of transcription 5B0.152
Mup4major urinary protein 40.152
Ncor2nuclear receptor co-repressor 20.130
Foxf2forkhead box F20.125
Mup5major urinary protein 50.123
Mup1major urinary protein 10.122
Mup3major urinary protein 30.114
Mup8major urinary protein 80.113
Mup9major urinary protein 90.110
Mup14major urinary protein 140.100
Lgr4leucine-rich repeat-containing G protein-coupled receptor 40.100
Mup11major urinary protein 110.099
Mup7major urinary protein 70.092
Pim1proviral integration site 10.089
Mup12major urinary protein 120.086
Dlx5distal-less homeobox 50.083
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.082
LOC100048885major urinary protein LOC1000488850.080
Mup13major urinary protein 130.076
Mup17major urinary protein 170.071
F2coagulation factor II0.071
Fgafibrinogen alpha chain0.066
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.062
Serpina3cserine (or cysteine) peptidase inhibitor, clade A, member 3C0.061
Nos3nitric oxide synthase 3, endothelial cell0.056
Il4rainterleukin 4 receptor, alpha0.056
Akr1c6aldo-keto reductase family 1, member C60.055
Onecut1one cut domain, family member 10.055
Clk4CDC like kinase 40.054
Lmx1bLIM homeobox transcription factor 1 beta0.053
Csf1rcolony stimulating factor 1 receptor0.052
Apofapolipoprotein F0.050
Mup2major urinary protein 20.050
Scarf2scavenger receptor class F, member 20.050
Adra1badrenergic receptor, alpha 1b0.049
Nrxn1neurexin I0.047
Fggfibrinogen gamma chain0.045
Agtr1aangiotensin II receptor, type 1a0.045
Cyp8b1cytochrome P450, family 8, subfamily b, polypeptide 10.045
Hrghistidine-rich glycoprotein0.044
Mup15major urinary protein 150.044
Serpina1bserine (or cysteine) preptidase inhibitor, clade A, member 1B0.044
Otcornithine transcarbamylase0.042
Ctsscathepsin S0.042
Ly86lymphocyte antigen 860.041
Mef2cmyocyte enhancer factor 2C0.041
VgfVGF nerve growth factor inducible0.041
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.040
Il1r1interleukin 1 receptor, type I0.039
Itih4inter alpha-trypsin inhibitor, heavy chain 40.039
Ambpalpha 1 microglobulin/bikunin0.038
Csf1colony stimulating factor 1 (macrophage)0.037
Nkx2-1NK2 homeobox 10.037
En1engrailed 10.036
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.036
Nr1h4nuclear receptor subfamily 1, group H, member 40.035
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.035
Spry4sprouty homolog 4 (Drosophila)0.034
Irs2insulin receptor substrate 20.034
Bmp4bone morphogenetic protein 40.033
Kng1kininogen 10.033
Pdx1pancreatic and duodenal homeobox 10.033
Ren1renin 1 structural0.032
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.032
Iigp1interferon inducible GTPase 10.031
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.031
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.030
Itih2inter-alpha trypsin inhibitor, heavy chain 20.030
Apoc4apolipoprotein C-IV0.030
Dmgdhdimethylglycine dehydrogenase precursor0.029
Hnf4ahepatic nuclear factor 4, alpha0.029
Ptpn11protein tyrosine phosphatase, non-receptor type 110.029
Saa4serum amyloid A 40.028
Plgplasminogen0.028
Nos1nitric oxide synthase 1, neuronal0.028
Serping1serine (or cysteine) peptidase inhibitor, clade G, member 10.028
Adra1aadrenergic receptor, alpha 1a0.026
Ptgs2prostaglandin-endoperoxide synthase 20.025
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.017
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
GID7Gid7p0.779
FYV10Fyv10p0.626
VID30Vid30p0.329
RMD5Rmd5p0.257
GID8Gid8p0.237
MOH1Moh1p0.211
GLG2Glg2p0.137
HXK1Hxk1p0.085
GSY1Gsy1p0.084
VID24Vid24p0.050
ARP8Arp8p0.049
BDH1Bdh1p0.046
VID28Vid28p0.045
SDS3Sds3p0.036
GLG1Glg1p0.033
YLR177Whypothetical protein0.030
TMA10Tma10p0.027
PIG2Pig2p0.026
EMI2Emi2p0.026
YIL077Chypothetical protein0.025
ICY1Icy1p0.023
GSY2Gsy2p0.022
GYL1Gyl1p0.022
THO2Tho2p0.022
SAK1Sak1p0.021
GTO3Gto3p0.021
SUR1Sur1p0.021
CTI6Cti6p0.021
TPS1Tps1p0.021
SPG3Spg3p0.021
RMR1Rmr1p0.019
PCL2Pcl2p0.018
YAP6Yap6p0.018
FAA1Faa1p0.018
AZF1Azf1p0.018
YKL023Whypothetical protein0.018
IZH3Izh3p0.018
PFK1Pfk1p0.017
YLR264C-Ahypothetical protein0.017
SRD1Srd1p0.017
PHO81Pho81p0.017
GLN1Gln1p0.017
IXR1Ixr1p0.016
SSA4Ssa4p0.016
YKR011Chypothetical protein0.016
HOR7Hor7p0.016
YLR162Whypothetical protein0.016
RGI1Rgi1p0.016
ASH1Ash1p0.016
YJL107Chypothetical protein0.016
YER039C-Ahypothetical protein0.015
ARP10Arp10p0.015
GLK1Glk1p0.015
RXT3Rxt3p0.015
LEU2Leu2p0.015
MER1Mer1p0.015
YDR186Chypothetical protein0.015
YOL038C-Ahypothetical protein0.015
DCC1Dcc1p0.015
GIP2Gip2p0.014
LEE1Lee1p0.014
HXT3Hxt3p0.014
YJL181Whypothetical protein0.014
YNR014Whypothetical protein0.014
IRA2Ira2p0.014
YHR009Chypothetical protein0.014
UME1Ume1p0.014
GPH1Gph1p0.014
YMR160Whypothetical protein0.014
ARE2Are2p0.013
IPK1Ipk1p0.013
BPH1Bph1p0.013
CLG1Clg1p0.013
PFK2Pfk2p0.013
CUP1-1Cup1-1p0.013
YLR281Chypothetical protein0.013
RRN5Rrn5p0.013
MBF1Mbf1p0.013
CAK1Cak1p0.013
CRP1Crp1p0.013
YBR085C-Ahypothetical protein0.013
SUC2Suc2p0.013
YAR068Whypothetical protein0.013
YPL229Whypothetical protein0.012
YGR053Chypothetical protein0.012
YDL176Whypothetical protein0.012
FMT1Fmt1p0.012
CAR2Car2p0.012
HXT7Hxt7p0.012
CIT2Cit2p0.012
CCP1Ccp1p0.012
EAP1Eap1p0.012
SPT16Spt16p0.012
CTK2Ctk2p0.012
ATP6Atp6p0.012
OCH1Och1p0.012
YMR210Whypothetical protein0.012
ZPS1Zps1p0.012
OPT2Opt2p0.012
ISR1Isr1p0.012