The network for 'midgut development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

midgut development

The process whose specific outcome is the progression of the midgut over time, from its formation to the mature structure. The midgut is the middle part of the alimentary canal from the stomach, or entrance of the bile duct, to, or including, the large intestine.

NameDescriptionProbabilityFunc Analog Organism
RARAretinoic acid receptor, alpha0.997
HDAC4histone deacetylase 40.994
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.991
MED25mediator complex subunit 250.990
LAMB1laminin, beta 10.913
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.873
NCOA1nuclear receptor coactivator 10.844
TCF4transcription factor 40.780
NLRC4NLR family, CARD domain containing 40.747
FERMT2fermitin family member 20.637
CASP4caspase 4, apoptosis-related cysteine peptidase0.393
ALDH2aldehyde dehydrogenase 2 family (mitochondrial)0.381
SPTBN1spectrin, beta, non-erythrocytic 10.331
HDAC9histone deacetylase 90.277
ID2inhibitor of DNA binding 2, dominant negative helix-loop-helix protein0.264
TAL1T-cell acute lymphocytic leukemia 10.232
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.203
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.195
ACTA2actin, alpha 2, smooth muscle, aorta0.193
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.182
RRS1RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)0.172
ZADH2zinc binding alcohol dehydrogenase domain containing 20.165
CAV1caveolin 1, caveolae protein, 22kDa0.158
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.154
ASCC2activating signal cointegrator 1 complex subunit 20.147
FZD1frizzled homolog 1 (Drosophila)0.145
BAP1BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)0.145
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.139
NOP58NOP58 ribonucleoprotein homolog (yeast)0.136
FBXW11F-box and WD repeat domain containing 110.134
MEF2Amyocyte enhancer factor 2A0.128
MEF2Cmyocyte enhancer factor 2C0.126
CREBBPCREB binding protein0.121
RIPK2receptor-interacting serine-threonine kinase 20.119
FLNAfilamin A, alpha0.118
NID1nidogen 10.117
EPAS1endothelial PAS domain protein 10.114
KANK2KN motif and ankyrin repeat domains 20.114
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.112
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.111
HDAC7histone deacetylase 70.101
TRPM7transient receptor potential cation channel, subfamily M, member 70.098
FLNBfilamin B, beta0.097
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.096
EP300E1A binding protein p3000.095
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.086
RBFOX2RNA binding protein, fox-1 homolog (C. elegans) 20.084
IRF2interferon regulatory factor 20.084
WDR1WD repeat domain 10.079
PBX1pre-B-cell leukemia homeobox 10.077
HRhairless homolog (mouse)0.075
CAV2caveolin 20.075
APPamyloid beta (A4) precursor protein0.074
SNAPINSNAP-associated protein0.073
PMLpromyelocytic leukemia0.066
NR4A1nuclear receptor subfamily 4, group A, member 10.066
TRPM6transient receptor potential cation channel, subfamily M, member 60.064
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.060
NR1H3nuclear receptor subfamily 1, group H, member 30.059
FOXF1forkhead box F10.057
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.057
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.057
ARandrogen receptor0.056
SMAD7SMAD family member 70.056
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein0.056
DTNBP1dystrobrevin binding protein 10.056
JUPjunction plakoglobin0.055
ACTN4actinin, alpha 40.054
GFI1Bgrowth factor independent 1B transcription repressor0.054
TNFRSF1Atumor necrosis factor receptor superfamily, member 1A0.054
MYLK2myosin light chain kinase 20.052
ACVR1Bactivin A receptor, type IB0.052
RXRBretinoid X receptor, beta0.052
MECP2methyl CpG binding protein 2 (Rett syndrome)0.052
GLIS2GLIS family zinc finger 20.052
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.049
TPM4tropomyosin 40.049
CNN2calponin 20.047
CARD16caspase recruitment domain family, member 160.047
ZHX2zinc fingers and homeoboxes 20.047
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.046
CRPC-reactive protein, pentraxin-related0.046
ZHX1zinc fingers and homeoboxes 10.046
SERTAD1SERTA domain containing 10.044
CDH2cadherin 2, type 1, N-cadherin (neuronal)0.043
MYOD1myogenic differentiation 10.043
FYCO1FYVE and coiled-coil domain containing 10.041
FOXF2forkhead box F20.041
MIF4GDMIF4G domain containing0.040
CD200CD200 molecule0.040
SDC2syndecan 20.040
CUL1cullin 10.040
MYL9myosin, light chain 9, regulatory0.039
PYCARDPYD and CARD domain containing0.038
CFBcomplement factor B0.037
RUNX1runt-related transcription factor 10.037
AXIN1axin 10.037
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Cyp12d1-pCG30489 gene product from transcript CG30489-RA0.168
Cyp12d1-dCG33503 gene product from transcript CG33503-RA0.121
OptixCG18455 gene product from transcript CG18455-RA0.105
cicubitus interruptus0.077
fkhfork head0.070
eyaeyes absent0.064
Myo61FMyosin 61F0.059
locolocomotion defects0.048
Cyp12a4CG6042 gene product from transcript CG6042-RA0.037
Atg18Autophagy-specific gene 180.036
imdimmune deficiency0.031
opaodd paired0.031
sogshort gastrulation0.029
CG16799CG16799 gene product from transcript CG16799-RA0.029
NotumCG13076 gene product from transcript CG13076-RB0.027
faxfailed axon connections0.027
Cyp4ac1CG14032 gene product from transcript CG14032-RA0.026
Ugt35aUDP-glycosyltransferase 35a0.025
Stat92ESignal-transducer and activator of transcription protein at 92E0.024
stmAstambha A0.024
LanALaminin A0.024
Cyp28a5CG8864 gene product from transcript CG8864-RA0.024
Cyp6g1CG8453 gene product from transcript CG8453-RA0.023
LanB1CG7123 gene product from transcript CG7123-RA0.023
danrdistal antenna-related0.022
Mef2Myocyte enhancer factor 20.021
slp1sloppy paired 10.021
PhmPeptidylglycine-alpha-hydroxylating monooxygenase0.020
mewmultiple edematous wings0.019
Cyp12e1CG14680 gene product from transcript CG14680-RC0.018
mib2mind bomb 20.018
HcfHost cell factor0.018
SAKSak kinase0.017
eveeven skipped0.017
CG6834CG6834 gene product from transcript CG6834-RA0.017
Tsp2ATetraspanin 2A0.017
Myd88CG2078 gene product from transcript CG2078-RA0.016
HLH54FCG5005 gene product from transcript CG5005-RA0.016
Cyp6a13CG2397 gene product from transcript CG2397-RA0.016
Nup153Nucleoporin 1530.016
fasfaint sausage0.016
CG6283CG6283 gene product from transcript CG6283-RA0.016
Src42ASrc oncogene at 42A0.016
mbcmyoblast city0.016
RpL38Ribosomal protein L380.015
rawCG12437 gene product from transcript CG12437-RB0.015
HrsHepatocyte growth factor regulated tyrosine kinase substrate0.015
Bre1CG10542 gene product from transcript CG10542-RA0.015
Cyp6d5CG3050 gene product from transcript CG3050-RA0.015
CG33303CG33303 gene product from transcript CG33303-RA0.014
dvedefective proventriculus0.014
Cyp28d1CG10833 gene product from transcript CG10833-RA0.014
Cyp12a5CG11821 gene product from transcript CG11821-RA0.014
CG3835CG3835 gene product from transcript CG3835-RB0.014
l(1)1Bilethal (1) 1Bi0.014
nkdnaked cuticle0.014
howheld out wings0.014
oafout at first0.014
tamoCG4057 gene product from transcript CG4057-RA0.013
HandCG18144 gene product from transcript CG18144-RA0.013
CG33120CG33120 gene product from transcript CG33120-RA0.013
Atg13Autophagy-specific gene 130.013
PknProtein kinase related to protein kinase N0.013
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gli3GLI-Kruppel family member GLI30.983
Id3inhibitor of DNA binding 30.962
Tcf4transcription factor 40.946
Shhsonic hedgehog0.928
Foxc1forkhead box C10.895
Lhx1LIM homeobox protein 10.891
Gli2GLI-Kruppel family member GLI20.880
Rarbretinoic acid receptor, beta0.862
Fgf8fibroblast growth factor 80.848
Bmp4bone morphogenetic protein 40.833
Id1inhibitor of DNA binding 10.826
Prrx1paired related homeobox 10.825
Fgfr1fibroblast growth factor receptor 10.813
Emx2empty spiracles homolog 2 (Drosophila)0.781
Otx2orthodenticle homolog 2 (Drosophila)0.762
Pax2paired box gene 20.752
Fgfr2fibroblast growth factor receptor 20.733
Emx1empty spiracles homolog 1 (Drosophila)0.705
Sox9SRY-box containing gene 90.682
Wnt3awingless-related MMTV integration site 3A0.681
Pitx2paired-like homeodomain transcription factor 20.650
Msx2homeobox, msh-like 20.621
Wnt10bwingless related MMTV integration site 10b0.620
Pax3paired box gene 30.610
Pax8paired box gene 80.606
Hspa5heat shock protein 50.589
Tbx1T-box 10.578
Rararetinoic acid receptor, alpha0.575
Rargretinoic acid receptor, gamma0.570
Ptenphosphatase and tensin homolog0.558
Tcf3transcription factor 30.541
Foxc2forkhead box C20.524
Casp4caspase 4, apoptosis-related cysteine peptidase0.516
Dkk1dickkopf homolog 1 (Xenopus laevis)0.515
Iqcb1IQ calmodulin-binding motif containing 10.493
Plxnd1plexin D10.492
Bmp7bone morphogenetic protein 70.489
Acvr1activin A receptor, type 10.482
Dlx5distal-less homeobox 50.443
Hoxa13homeobox A130.435
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.418
Trp63transformation related protein 630.418
Ror2receptor tyrosine kinase-like orphan receptor 20.403
Hoxa2homeobox A20.385
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.379
Zic1zinc finger protein of the cerebellum 10.361
Pou3f3POU domain, class 3, transcription factor 30.353
Gdnfglial cell line derived neurotrophic factor0.351
Wnt5awingless-related MMTV integration site 5A0.333
Trp53transformation related protein 530.313
Rspo2R-spondin 2 homolog (Xenopus laevis)0.292
Ece1endothelin converting enzyme 10.283
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.280
Wnt7awingless-related MMTV integration site 7A0.265
Otx1orthodenticle homolog 1 (Drosophila)0.260
Hoxa10homeobox A100.257
Hdac4histone deacetylase 40.255
Zic2zinc finger protein of the cerebellum 20.253
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.241
Gsk3bglycogen synthase kinase 3 beta0.239
Lrp8low density lipoprotein receptor-related protein 8, apolipoprotein e receptor0.238
BmperBMP-binding endothelial regulator0.236
Trp73transformation related protein 730.227
Tbx3T-box 30.214
Pou3f2POU domain, class 3, transcription factor 20.214
Gscgoosecoid homeobox0.213
Hoxd3homeobox D30.200
Neurog1neurogenin 10.199
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.198
Mitfmicrophthalmia-associated transcription factor0.196
Tcfap2atranscription factor AP-2, alpha0.195
Msx1homeobox, msh-like 10.186
Olig1oligodendrocyte transcription factor 10.184
RoraRAR-related orphan receptor alpha0.174
Grid1glutamate receptor, ionotropic, delta 10.172
Gli1GLI-Kruppel family member GLI10.170
Pax6paired box gene 60.170
Hoxa3homeobox A30.167
Nrp1neuropilin 10.160
Fgf10fibroblast growth factor 100.157
Foxf2forkhead box F20.154
Hand2heart and neural crest derivatives expressed transcript 20.154
Zeb2zinc finger E-box binding homeobox 20.152
Col13a1collagen, type XIII, alpha 10.150
Pcsk5proprotein convertase subtilisin/kexin type 50.150
Etv4ets variant gene 4 (E1A enhancer binding protein, E1AF)0.148
Lrp6low density lipoprotein receptor-related protein 60.148
Zic3zinc finger protein of the cerebellum 30.148
Prss58protease, serine 580.147
Fzd10frizzled homolog 10 (Drosophila)0.143
Nphp4nephronophthisis 4 (juvenile) homolog (human)0.143
Actn1actinin, alpha 10.141
Socs1suppressor of cytokine signaling 10.140
Wt1Wilms tumor 1 homolog0.134
Porcnporcupine homolog (Drosophila)0.131
Rspo1R-spondin homolog (Xenopus laevis)0.130
Cfc1cripto, FRL-1, cryptic family 10.128
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Id3inhibitor of DNA binding 30.537
Cyp51cytochrome P450, family 510.473
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.321
Idi1isopentenyl-diphosphate delta isomerase 10.189
Marcksmyristoylated alanine rich protein kinase C substrate0.068
Id1inhibitor of DNA binding 10.058
FcgrtFc fragment of IgG, receptor, transporter, alpha0.051
Casp1caspase 10.046
Anxa1annexin A10.042
Cdk2cyclin dependent kinase 20.040
Ednrbendothelin receptor type B0.039
Hmgcr3-hydroxy-3-methylglutaryl-Coenzyme A reductase0.036
Ctsccathepsin C0.033
Sqlesqualene epoxidase0.033
Cd9CD9 molecule0.028
Tlr4toll-like receptor 40.027
Tcfe2atranscription factor E2a0.026
Casp2caspase 20.026
Bmpr1abone morphogenetic protein receptor, type IA0.024
Map3k1mitogen activated protein kinase kinase kinase 10.023
Ppap2bphosphatidic acid phosphatase type 2B0.023
Aif1allograft inflammatory factor 10.020
Cald1caldesmon 10.019
Casp8caspase 80.019
Dhfrdihydrofolate reductase0.018
Dusp6dual specificity phosphatase 60.018
Ptprcprotein tyrosine phosphatase, receptor type, C0.018
Acat3acetyl-Coenzyme A acetyltransferase 30.018
Bckdhabranched chain ketoacid dehydrogenase E1, alpha polypeptide0.017
Insig1insulin induced gene 10.017
Cpt1acarnitine palmitoyltransferase 1a, liver0.017
Gstm2glutathione S-transferase mu 20.017
Akr1c14aldo-keto reductase family 1, member C140.016
Tcf4transcription factor 40.016
Ephx1epoxide hydrolase 1, microsomal0.016
Tstthiosulfate sulfurtransferase0.016
Tgfbr2transforming growth factor, beta receptor II0.016
Pcnxl3pecanex-like 3 (Drosophila)0.016
Ss18l1synovial sarcoma translocation gene on chromosome 18-like 10.015
Cd47Cd47 molecule0.015
Gbp2guanylate binding protein 20.015
Ddcdopa decarboxylase (aromatic L-amino acid decarboxylase)0.015
Casp7caspase 70.015
Igfbp5insulin-like growth factor binding protein 50.014
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.014
Ppp3caprotein phosphatase 3, catalytic subunit, alpha isoform0.014
Lphn2latrophilin 20.014
Casp6caspase 60.014
Fdft1farnesyl diphosphate farnesyl transferase 10.013
Adam17ADAM metallopeptidase domain 170.013
Ugt2b36UDP glucuronosyltransferase 2 family, polypeptide B360.013
Ccnd1cyclin D10.013
Jak1Janus kinase 10.013
Cxxc4CXXC finger 40.012
Sp1Sp1 transcription factor0.012
Nat1N-acetyltransferase 10.012
Cmtm3CKLF-like MARVEL transmembrane domain containing 30.011
Itga1integrin, alpha 10.011
Gpc3glypican 30.011
Mat1amethionine adenosyltransferase I, alpha0.011
Unguracil-DNA glycosylase0.011
Sc4molsterol-C4-methyl oxidase-like0.010
Nr2f2nuclear receptor subfamily 2, group F, member 20.010
Pls3plastin 3 (T-isoform)0.010
Galgalanin prepropeptide0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism