The network for 'positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus

Any positive regulation of transcription from RNA polymerase II promoter that is involved in cellular response to chemical stimulus.

NameDescriptionProbabilityFunc Analog Organism
SMAD1SMAD family member 11.000
RARAretinoic acid receptor, alpha1.000
SMAD5SMAD family member 51.000
SMAD3SMAD family member 30.999
BMPR1Abone morphogenetic protein receptor, type IA0.994
MED25mediator complex subunit 250.993
NCOA1nuclear receptor coactivator 10.976
SMAD2SMAD family member 20.925
SMAD4SMAD family member 40.906
SMURF1SMAD specific E3 ubiquitin protein ligase 10.843
RABAC1Rab acceptor 1 (prenylated)0.807
SMURF2SMAD specific E3 ubiquitin protein ligase 20.776
CREBBPCREB binding protein0.749
SP1Sp1 transcription factor0.676
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.654
SMAD7SMAD family member 70.570
FSTL1follistatin-like 10.522
ARandrogen receptor0.488
SMAD6SMAD family member 60.343
NCOR2nuclear receptor corepressor 20.271
SKIv-ski sarcoma viral oncogene homolog (avian)0.257
NEDD4neural precursor cell expressed, developmentally down-regulated 40.253
STX8syntaxin 80.215
RUNX1runt-related transcription factor 10.137
MKL2MKL/myocardin-like 20.096
KANK2KN motif and ankyrin repeat domains 20.091
NCOA6nuclear receptor coactivator 60.090
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.089
TRAF4TNF receptor-associated factor 40.085
VPS24vacuolar protein sorting 24 homolog (S. cerevisiae)0.077
NCOA3nuclear receptor coactivator 30.071
RXRBretinoid X receptor, beta0.064
PIAS1protein inhibitor of activated STAT, 10.063
EMDemerin0.063
FBXL15F-box and leucine-rich repeat protein 150.062
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.057
WWP1WW domain containing E3 ubiquitin protein ligase 10.052
SNRNP70small nuclear ribonucleoprotein 70kDa (U1)0.051
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.050
NCOA2nuclear receptor coactivator 20.050
ZDHHC3zinc finger, DHHC-type containing 30.048
PPIL4peptidylprolyl isomerase (cyclophilin)-like 40.048
NOGnoggin0.042
NEDD9neural precursor cell expressed, developmentally down-regulated 90.041
RNF11ring finger protein 110.041
ICKintestinal cell (MAK-like) kinase0.040
MAST4microtubule associated serine/threonine kinase family member 40.040
ZFYVE9zinc finger, FYVE domain containing 90.040
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 10.038
ATF7IPactivating transcription factor 7 interacting protein0.037
EP300E1A binding protein p3000.034
JUNjun proto-oncogene0.034
ZBED5zinc finger, BED-type containing 50.033
ING2inhibitor of growth family, member 20.033
DCP1BDCP1 decapping enzyme homolog B (S. cerevisiae)0.032
NFYCnuclear transcription factor Y, gamma0.032
GMEB1glucocorticoid modulatory element binding protein 10.031
FOSFBJ murine osteosarcoma viral oncogene homolog0.030
SPG20spastic paraplegia 20 (Troyer syndrome)0.030
NR1H3nuclear receptor subfamily 1, group H, member 30.030
SEC24DSEC24 family, member D (S. cerevisiae)0.029
MSX2msh homeobox 20.029
ACVR1Bactivin A receptor, type IB0.029
INPP4Ainositol polyphosphate-4-phosphatase, type I, 107kDa0.029
UHRF2ubiquitin-like with PHD and ring finger domains 20.027
ANKRD13Aankyrin repeat domain 13A0.027
HRhairless homolog (mouse)0.026
PLEKHO1pleckstrin homology domain containing, family O member 10.026
NR0B2nuclear receptor subfamily 0, group B, member 20.026
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.025
TADA3transcriptional adaptor 30.024
BMPR1Bbone morphogenetic protein receptor, type IB0.023
NLKnemo-like kinase0.023
FOXO1forkhead box O10.023
PRKD2protein kinase D20.022
DACH1dachshund homolog 1 (Drosophila)0.021
SKILSKI-like oncogene0.020
FHL2four and a half LIM domains 20.020
PEF1penta-EF-hand domain containing 10.020
CXXC5CXXC finger protein 50.018
PRRC1proline-rich coiled-coil 10.018
YAP1Yes-associated protein 10.018
MGAMAX gene associated0.017
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.017
BMP4bone morphogenetic protein 40.017
JUNBjun B proto-oncogene0.017
ZNF251zinc finger protein 2510.017
BCL3B-cell CLL/lymphoma 30.016
PTPN12protein tyrosine phosphatase, non-receptor type 120.016
NOTCH2notch 20.016
PSENENpresenilin enhancer 2 homolog (C. elegans)0.016
FGFR1fibroblast growth factor receptor 10.016
SOX5SRY (sex determining region Y)-box 50.015
SOX7SRY (sex determining region Y)-box 70.015
BADBCL2-associated agonist of cell death0.015
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.015
BMP2bone morphogenetic protein 20.014
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.014
C14orf93chromosome 14 open reading frame 930.014
GULP1GULP, engulfment adaptor PTB domain containing 10.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
hthhomothorax0.046
hhhedgehog0.033
enengrailed0.023
cicubitus interruptus0.019
DadDaughters against dpp0.018
rhorhomboid0.016
eyaeyes absent0.016
wgwingless0.015
Pk61CProtein kinase 61C0.013
SerSerrate0.012
Vap-33-1CG5014 gene product from transcript CG5014-RB0.011
argosCG4531 gene product from transcript CG4531-RA0.011
shnschnurri0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Smad4MAD homolog 4 (Drosophila)1.000
Prrx1paired related homeobox 11.000
Sox9SRY-box containing gene 91.000
Fgfr2fibroblast growth factor receptor 21.000
Msx1homeobox, msh-like 11.000
Shhsonic hedgehog1.000
Bmp4bone morphogenetic protein 40.999
Ctnnb1catenin (cadherin associated protein), beta 10.999
Gli3GLI-Kruppel family member GLI30.998
Foxc1forkhead box C10.998
Smad1MAD homolog 1 (Drosophila)0.997
Bmp7bone morphogenetic protein 70.995
Tgfb2transforming growth factor, beta 20.995
Fgfr1fibroblast growth factor receptor 10.994
Tbx1T-box 10.994
Dlx5distal-less homeobox 50.993
Hand2heart and neural crest derivatives expressed transcript 20.992
Fgf8fibroblast growth factor 80.990
Ptenphosphatase and tensin homolog0.988
Apcadenomatosis polyposis coli0.987
Smad3MAD homolog 3 (Drosophila)0.985
Smosmoothened homolog (Drosophila)0.984
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.975
Msx2homeobox, msh-like 20.972
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.967
Eya1eyes absent 1 homolog (Drosophila)0.958
Gli2GLI-Kruppel family member GLI20.957
Pax3paired box gene 30.946
Tcfap2atranscription factor AP-2, alpha0.945
Otx2orthodenticle homolog 2 (Drosophila)0.934
Fgfr3fibroblast growth factor receptor 30.933
Rargretinoic acid receptor, gamma0.891
Trp53transformation related protein 530.890
Pbx1pre B-cell leukemia transcription factor 10.889
Runx2runt related transcription factor 20.889
Ptch1patched homolog 10.886
Hand1heart and neural crest derivatives expressed transcript 10.871
Tgfbr2transforming growth factor, beta receptor II0.864
Bmpr1abone morphogenetic protein receptor, type 1A0.861
Gscgoosecoid homeobox0.856
Acvr1activin A receptor, type 10.847
Erbb2ipErbb2 interacting protein0.820
Axin1axin 10.818
Foxc2forkhead box C20.813
Ednraendothelin receptor type A0.794
Rararetinoic acid receptor, alpha0.778
Foxg1forkhead box G10.744
Ror2receptor tyrosine kinase-like orphan receptor 20.734
Rarbretinoic acid receptor, beta0.734
Prrx2paired related homeobox 20.715
Pitx2paired-like homeodomain transcription factor 20.713
Bmp2bone morphogenetic protein 20.702
Pax9paired box gene 90.664
Alx4aristaless-like homeobox 40.654
Rspo2R-spondin 2 homolog (Xenopus laevis)0.573
Nr2f2nuclear receptor subfamily 2, group F, member 20.535
Smad2MAD homolog 2 (Drosophila)0.508
Rxraretinoid X receptor alpha0.503
Alx1ALX homeobox 10.490
Chrdchordin0.486
Hoxa2homeobox A20.477
Dlx6distal-less homeobox 60.378
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.377
Gata4GATA binding protein 40.364
Smad6MAD homolog 6 (Drosophila)0.357
Dlx1distal-less homeobox 10.351
Pax2paired box gene 20.341
Ece1endothelin converting enzyme 10.339
Fgf10fibroblast growth factor 100.326
Esr1estrogen receptor 1 (alpha)0.306
Lrp6low density lipoprotein receptor-related protein 60.305
Map3k7mitogen-activated protein kinase kinase kinase 70.275
Zeb1zinc finger E-box binding homeobox 10.262
Smad7MAD homolog 7 (Drosophila)0.251
Hoxa3homeobox A30.248
Ptpn11protein tyrosine phosphatase, non-receptor type 110.232
Col1a1collagen, type I, alpha 10.205
Tbx3T-box 30.204
Tgfb1transforming growth factor, beta 10.194
Csf1colony stimulating factor 1 (macrophage)0.184
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.180
Meox2mesenchyme homeobox 20.177
Mn1meningioma 10.170
Alx3aristaless-like homeobox 30.166
Nr2f1nuclear receptor subfamily 2, group F, member 10.161
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.153
BrafBraf transforming gene0.142
Yap1yes-associated protein 10.138
Vegfavascular endothelial growth factor A0.136
Trp63transformation related protein 630.122
Dlx2distal-less homeobox 20.118
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.118
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.115
Pitx1paired-like homeodomain transcription factor 10.100
Rnf111ring finger 1110.097
Nodalnodal0.094
Hoxa1homeobox A10.089
Lrp5low density lipoprotein receptor-related protein 50.088
Foxa2forkhead box A20.084
Prkg1protein kinase, cGMP-dependent, type I0.080
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism