The network for 'positive regulation of intracellular estrogen receptor signaling pathway' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of intracellular estrogen receptor signaling pathway

Any process that activates or increases the frequency, rate or extent of the activity of an intracellular estrogen receptor signaling pathway.

NameDescriptionProbabilityFunc Analog Organism
ESR1estrogen receptor 10.962
NCOA2nuclear receptor coactivator 20.917
NCOA3nuclear receptor coactivator 30.844
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.842
CREBBPCREB binding protein0.796
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 70.673
NCOA1nuclear receptor coactivator 10.356
NFAT5nuclear factor of activated T-cells 5, tonicity-responsive0.312
NCOA6nuclear receptor coactivator 60.274
POU5F1POU class 5 homeobox 10.213
ARandrogen receptor0.114
EP300E1A binding protein p3000.111
RBM4RNA binding motif protein 40.079
SF1splicing factor 10.079
SMAD1SMAD family member 10.076
DDX5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.070
ASH2Lash2 (absent, small, or homeotic)-like (Drosophila)0.050
HNRNPH1heterogeneous nuclear ribonucleoprotein H1 (H)0.046
MYST2MYST histone acetyltransferase 20.045
RBBP5retinoblastoma binding protein 50.034
CDK2cyclin-dependent kinase 20.023
CDK11Bcyclin-dependent kinase 11B0.023
WDR5WD repeat domain 50.018
FOXO1forkhead box O10.017
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.017
ERGv-ets erythroblastosis virus E26 oncogene homolog (avian)0.016
HNRNPA0heterogeneous nuclear ribonucleoprotein A00.015
TSC22D1TSC22 domain family, member 10.015
WWP2WW domain containing E3 ubiquitin protein ligase 20.014
KAT5K(lysine) acetyltransferase 50.014
SH3RF3SH3 domain containing ring finger 30.013
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 60.013
RARAretinoic acid receptor, alpha0.013
MED10mediator complex subunit 100.010
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Esr1estrogen receptor 1 (alpha)0.998
Arandrogen receptor0.891
Bglapbone gamma carboxyglutamate protein0.853
Ghrgrowth hormone receptor0.849
Pax8paired box gene 80.826
Lhcgrluteinizing hormone/choriogonadotropin receptor0.802
Ptenphosphatase and tensin homolog0.761
Hnrnph1heterogeneous nuclear ribonucleoprotein H10.731
Amhr2anti-Mullerian hormone type 2 receptor0.705
Hnrnpa2b1heterogeneous nuclear ribonucleoprotein A2/B10.612
Kiss1KiSS-1 metastasis-suppressor0.542
Hnrnpkheterogeneous nuclear ribonucleoprotein K0.538
Lepleptin0.481
Duox2dual oxidase 20.459
Cyp19a1cytochrome P450, family 19, subfamily a, polypeptide 10.406
Drd2dopamine receptor D20.356
Kiss1rKISS1 receptor0.353
Leprleptin receptor0.298
Prlrprolactin receptor0.257
Ythdc1YTH domain containing 10.207
Ddx17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.188
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.184
Foxf2forkhead box F20.183
Cdkn1bcyclin-dependent kinase inhibitor 1B0.179
Nr5a1nuclear receptor subfamily 5, group A, member 10.167
Inhainhibin alpha0.164
Ahraryl-hydrocarbon receptor0.152
Rac1RAS-related C3 botulinum substrate 10.150
Fshrfollicle stimulating hormone receptor0.145
Gnrhrgonadotropin releasing hormone receptor0.125
Hnrnprheterogeneous nuclear ribonucleoprotein R0.104
Tial1Tia1 cytotoxic granule-associated RNA binding protein-like 10.091
Wsb1WD repeat and SOCS box-containing 10.090
Ncoa6nuclear receptor coactivator 60.085
Zfp326zinc finger protein 3260.082
Matr3matrin 30.078
Ddx5DEAD (Asp-Glu-Ala-Asp) box polypeptide 50.078
Thrbthyroid hormone receptor beta0.077
Gnrh1gonadotropin releasing hormone 10.076
Prpf38bPRP38 pre-mRNA processing factor 38 (yeast) domain containing B0.068
Cftrcystic fibrosis transmembrane conductance regulator homolog0.061
Myf5myogenic factor 50.058
Pgrprogesterone receptor0.056
BC018507cDNA sequence BC0185070.055
Kitkit oncogene0.054
Hoxa10homeobox A100.053
Inhbainhibin beta-A0.049
Smad1MAD homolog 1 (Drosophila)0.048
Srsf1serine/arginine-rich splicing factor 10.048
Srsf11serine/arginine-rich splicing factor 110.045
Fbxo11F-box protein 110.045
Esr2estrogen receptor 2 (beta)0.040
Nr0b1nuclear receptor subfamily 0, group B, member 10.039
Egr1early growth response 10.038
Bcl2B-cell leukemia/lymphoma 20.038
Cgaglycoprotein hormones, alpha subunit0.038
Hnrpdlheterogeneous nuclear ribonucleoprotein D-like0.038
Hnrnph3heterogeneous nuclear ribonucleoprotein H30.036
Npc1Niemann Pick type C10.034
Retnresistin0.034
Thrathyroid hormone receptor alpha0.033
Srsf6serine/arginine-rich splicing factor 60.032
Srsf7serine/arginine-rich splicing factor 70.031
E2f1E2F transcription factor 10.030
Ptpn11protein tyrosine phosphatase, non-receptor type 110.030
C78704expressed sequence C787040.030
Plekha5pleckstrin homology domain containing, family A member 50.030
Mat2amethionine adenosyltransferase II, alpha0.029
Ptgfrprostaglandin F receptor0.029
Rnf145ring finger protein 1450.029
Gnaqguanine nucleotide binding protein, alpha q polypeptide0.029
Pitx2paired-like homeodomain transcription factor 20.028
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.028
Atxn1ataxin 10.028
Paxip1PAX interacting (with transcription-activation domain) protein 10.028
Cldn8claudin 80.028
Gcfc1GC-rich sequence DNA-binding factor 10.028
Slc34a2solute carrier family 34 (sodium phosphate), member 20.027
Hnrnph2heterogeneous nuclear ribonucleoprotein H20.027
Gata5GATA binding protein 50.026
Ube2d2ubiquitin-conjugating enzyme E2D 20.026
Ubp1upstream binding protein 10.025
Ywhaqtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.025
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.025
Tshrthyroid stimulating hormone receptor0.024
Ivns1abpinfluenza virus NS1A binding protein0.022
Gata6GATA binding protein 60.022
Zfp185zinc finger protein 1850.022
Tia1cytotoxic granule-associated RNA binding protein 10.022
Khdrbs1KH domain containing, RNA binding, signal transduction associated 10.022
Ctnnb1catenin (cadherin associated protein), beta 10.022
WwoxWW domain-containing oxidoreductase0.021
Cdh1cadherin 10.021
Hnrnpa3heterogeneous nuclear ribonucleoprotein A30.021
Gata3GATA binding protein 30.021
Rbbp6retinoblastoma binding protein 60.021
Srsf5serine/arginine-rich splicing factor 50.021
C78891expressed sequence C788910.021
Irs2insulin receptor substrate 20.021
Luc7l3LUC7-like 3 (S. cerevisiae)0.021
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism