The network for 'regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic process

Any process that modulates the frequency, rate or extent of protein ubiquitination involved in ubiquitin-dependent protein catabolic process.

NameDescriptionProbabilityFunc Analog Organism
BCAR1breast cancer anti-estrogen resistance 10.788
PMLpromyelocytic leukemia0.544
DAXXdeath-domain associated protein0.426
TRIM39tripartite motif containing 390.370
MED15mediator complex subunit 150.336
ATF5activating transcription factor 50.306
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.280
TRIM5tripartite motif containing 50.233
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.232
PTK2PTK2 protein tyrosine kinase 20.225
BCL2L1BCL2-like 10.224
TP53tumor protein p530.195
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.194
FASFas (TNF receptor superfamily, member 6)0.174
TRIM21tripartite motif containing 210.161
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.158
GSK3Bglycogen synthase kinase 3 beta0.151
SRCIN1SRC kinase signaling inhibitor 10.125
MAGI3membrane associated guanylate kinase, WW and PDZ domain containing 30.108
PTPN1protein tyrosine phosphatase, non-receptor type 10.104
APH1Aanterior pharynx defective 1 homolog A (C. elegans)0.104
USP7ubiquitin specific peptidase 7 (herpes virus-associated)0.100
ARIH2ariadne homolog 2 (Drosophila)0.098
SP100SP100 nuclear antigen0.098
PTPRAprotein tyrosine phosphatase, receptor type, A0.091
WASLWiskott-Aldrich syndrome-like0.089
CUL1cullin 10.081
SYVN1synovial apoptosis inhibitor 1, synoviolin0.064
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.059
RNF5ring finger protein 50.055
TRIM32tripartite motif containing 320.050
FLNBfilamin B, beta0.048
PLSCR1phospholipid scramblase 10.048
PDCD6IPprogrammed cell death 6 interacting protein0.045
CFLARCASP8 and FADD-like apoptosis regulator0.042
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.042
PTPN23protein tyrosine phosphatase, non-receptor type 230.041
DNAJB2DnaJ (Hsp40) homolog, subfamily B, member 20.041
BTRCbeta-transducin repeat containing0.040
SIRT2sirtuin 20.040
UHRF2ubiquitin-like with PHD and ring finger domains 20.036
PEX26peroxisomal biogenesis factor 260.033
CCDC6coiled-coil domain containing 60.030
SKP1S-phase kinase-associated protein 10.029
MATKmegakaryocyte-associated tyrosine kinase0.029
BAK1BCL2-antagonist/killer 10.028
PKP4plakophilin 40.027
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.026
BANPBTG3 associated nuclear protein0.026
TRIM43tripartite motif containing 430.025
CLTCclathrin, heavy chain (Hc)0.024
CAV1caveolin 1, caveolae protein, 22kDa0.022
UBE2Uubiquitin-conjugating enzyme E2U (putative)0.021
ACTN2actinin, alpha 20.020
PFDN1prefoldin subunit 10.020
MAP1Amicrotubule-associated protein 1A0.019
SYNE1spectrin repeat containing, nuclear envelope 10.019
USPL1ubiquitin specific peptidase like 10.019
TGFB1I1transforming growth factor beta 1 induced transcript 10.017
RNF11ring finger protein 110.017
MAKmale germ cell-associated kinase0.016
PRKCAprotein kinase C, alpha0.016
PIAS4protein inhibitor of activated STAT, 40.015
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.015
MAPK7mitogen-activated protein kinase 70.015
HDAC6histone deacetylase 60.015
ZNF473zinc finger protein 4730.014
PHF17PHD finger protein 170.014
USP4ubiquitin specific peptidase 4 (proto-oncogene)0.014
TOM1L1target of myb1 (chicken)-like 10.014
ZNRF1zinc and ring finger 10.014
ZFYVE1zinc finger, FYVE domain containing 10.014
MMS22LMMS22-like, DNA repair protein0.013
MAD2L2MAD2 mitotic arrest deficient-like 2 (yeast)0.013
NMIN-myc (and STAT) interactor0.013
CDK6cyclin-dependent kinase 60.013
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.013
CDK4cyclin-dependent kinase 40.012
QPRTquinolinate phosphoribosyltransferase0.012
FBXW2F-box and WD repeat domain containing 20.011
AMFRautocrine motility factor receptor0.011
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.010
DNM1dynamin 10.010
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
wnt4awingless-type MMTV integration site family, member 4a0.020
arnt2aryl hydrocarbon receptor nuclear translocator 20.020
trpm7transient receptor potential cation channel, subfamily M, member 70.018
slc12a3solute carrier family 12 (sodium/chloride transporters), member 30.017
hmgb1ahigh-mobility group box 1a0.014
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.014
mapk14amitogen-activated protein kinase 14a0.013
lef1lymphocyte enhancer binding factor 10.013
ntn2netrin 20.012
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ctnnb1catenin (cadherin associated protein), beta 10.892
Psen1presenilin 10.757
Gsk3bglycogen synthase kinase 3 beta0.668
Atf4activating transcription factor 40.566
Trp53transformation related protein 530.524
Notch1Notch gene homolog 1 (Drosophila)0.379
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.366
Wnt4wingless-related MMTV integration site 40.201
Dkk1dickkopf homolog 1 (Xenopus laevis)0.198
Pax2paired box gene 20.192
Wnt3awingless-related MMTV integration site 3A0.181
Notch2Notch gene homolog 2 (Drosophila)0.166
Setdb1SET domain, bifurcated 10.165
Lef1lymphoid enhancer binding factor 10.143
Lrp6low density lipoprotein receptor-related protein 60.131
Emx2empty spiracles homolog 2 (Drosophila)0.113
Prkceprotein kinase C, epsilon0.107
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.105
Smad7MAD homolog 7 (Drosophila)0.100
Lhx1LIM homeobox protein 10.087
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.083
Ncoa3nuclear receptor coactivator 30.079
Apcadenomatosis polyposis coli0.075
Appamyloid beta (A4) precursor protein0.068
Pax8paired box gene 80.066
Axin1axin 10.062
Fgfr1fibroblast growth factor receptor 10.059
Sap18Sin3-associated polypeptide 180.058
Wnt10bwingless related MMTV integration site 10b0.057
Gdnfglial cell line derived neurotrophic factor0.056
Smad6MAD homolog 6 (Drosophila)0.052
Rnf111ring finger 1110.052
SrcRous sarcoma oncogene0.048
Ptenphosphatase and tensin homolog0.047
Mdm2transformed mouse 3T3 cell double minute 20.046
Lama5laminin, alpha 50.045
Gli3GLI-Kruppel family member GLI30.042
Gli1GLI-Kruppel family member GLI10.042
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.038
Bcar1breast cancer anti-estrogen resistance 10.038
Ror2receptor tyrosine kinase-like orphan receptor 20.036
Dact1dapper homolog 1, antagonist of beta-catenin (xenopus)0.036
Fzd10frizzled homolog 10 (Drosophila)0.034
Gli2GLI-Kruppel family member GLI20.034
Itga3integrin alpha 30.033
Otx1orthodenticle homolog 1 (Drosophila)0.032
Pou3f3POU domain, class 3, transcription factor 30.030
Hoxb6homeobox B60.030
Zfp219zinc finger protein 2190.030
Shhsonic hedgehog0.030
Apoeapolipoprotein E0.030
Nsfl1cNSFL1 (p97) cofactor (p47)0.030
Pofut1protein O-fucosyltransferase 10.029
Wnt3wingless-related MMTV integration site 30.029
Porcnporcupine homolog (Drosophila)0.029
Dll1delta-like 1 (Drosophila)0.028
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.028
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.027
Hcn4hyperpolarization-activated, cyclic nucleotide-gated K+ 40.027
Lrp5low density lipoprotein receptor-related protein 50.027
Hoxc9homeobox C90.026
Tbx3T-box 30.026
Ptch1patched homolog 10.025
Rargretinoic acid receptor, gamma0.025
Retret proto-oncogene0.024
Jag2jagged 20.024
Rarbretinoic acid receptor, beta0.024
Ptmaprothymosin alpha0.024
Epha2Eph receptor A20.024
Bmp4bone morphogenetic protein 40.024
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.023
Pou3f1POU domain, class 3, transcription factor 10.022
Wnt9awingless-type MMTV integration site 9A0.022
Nck2non-catalytic region of tyrosine kinase adaptor protein 20.022
Fgf18fibroblast growth factor 180.022
Wnt1wingless-related MMTV integration site 10.021
Sertad2SERTA domain containing 20.021
Lgals3lectin, galactose binding, soluble 30.021
Pick1protein interacting with C kinase 10.020
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.020
Vangl2vang-like 2 (van gogh, Drosophila)0.020
DaxxFas death domain-associated protein0.019
Tnks1bp1tankyrase 1 binding protein 10.018
Rnf19aring finger protein 19A0.018
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.018
Tbx2T-box 20.017
Lrp4low density lipoprotein receptor-related protein 40.017
Tcf7l1transcription factor 7-like 1 (T-cell specific, HMG box)0.017
Psen2presenilin 20.017
Hoxd11homeobox D110.017
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.017
Fzd8frizzled homolog 8 (Drosophila)0.017
Amhr2anti-Mullerian hormone type 2 receptor0.016
Cdkn1bcyclin-dependent kinase inhibitor 1B0.016
Wnt6wingless-related MMTV integration site 60.016
Clstn1calsyntenin 10.016
Tgfatransforming growth factor alpha0.016
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Psmd2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism