The network for 'regulation of high density lipoprotein particle clearance' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of high density lipoprotein particle clearance

Any process that modulates the rate, frequency or extent of high-density lipoprotein particle clearance. High-density lipoprotein particle clearance is the process in which a high-density lipoprotein particle is removed from the blood via receptor-mediated endocytosis and its constituent parts degraded.

NameDescriptionProbabilityFunc Analog Organism
APOA1apolipoprotein A-I1.000
RPL18Aribosomal protein L18a1.000
MDKmidkine (neurite growth-promoting factor 2)0.725
FGAfibrinogen alpha chain0.492
APOBapolipoprotein B (including Ag(x) antigen)0.348
APOA2apolipoprotein A-II0.333
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.287
RIBC2RIB43A domain with coiled-coils 20.243
BAATbile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)0.113
PLA2G1Bphospholipase A2, group IB (pancreas)0.101
HPD4-hydroxyphenylpyruvate dioxygenase0.092
CA5Acarbonic anhydrase VA, mitochondrial0.082
PAHphenylalanine hydroxylase0.073
HAO1hydroxyacid oxidase (glycolate oxidase) 10.065
SERPINA6serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 60.064
FABP1fatty acid binding protein 1, liver0.060
APOA4apolipoprotein A-IV0.057
APOC1apolipoprotein C-I0.056
OTCornithine carbamoyltransferase0.055
UBE2Zubiquitin-conjugating enzyme E2Z0.051
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.051
PON1paraoxonase 10.051
CPB2carboxypeptidase B2 (plasma)0.050
LCATlecithin-cholesterol acyltransferase0.049
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.049
G6PCglucose-6-phosphatase, catalytic subunit0.049
C4BPBcomplement component 4 binding protein, beta0.046
MAT1Amethionine adenosyltransferase I, alpha0.045
KNG1kininogen 10.045
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.040
LECT2leukocyte cell-derived chemotaxin 20.039
FGGfibrinogen gamma chain0.039
ALDOBaldolase B, fructose-bisphosphate0.036
AMBPalpha-1-microglobulin/bikunin precursor0.035
APOC2apolipoprotein C-II0.034
CRPC-reactive protein, pentraxin-related0.034
C4BPAcomplement component 4 binding protein, alpha0.033
F11coagulation factor XI0.033
ORM2orosomucoid 20.032
APOC4apolipoprotein C-IV0.032
MBL2mannose-binding lectin (protein C) 2, soluble0.031
HALhistidine ammonia-lyase0.030
MASP2mannan-binding lectin serine peptidase 20.030
BHMTbetaine--homocysteine S-methyltransferase0.030
RPL36ribosomal protein L360.030
AKR1C4aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)0.029
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.028
REG1Aregenerating islet-derived 1 alpha0.028
PKLRpyruvate kinase, liver and RBC0.027
ORM1orosomucoid 10.027
ADH6alcohol dehydrogenase 6 (class V)0.026
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.024
TREHtrehalase (brush-border membrane glycoprotein)0.024
SLC38A3solute carrier family 38, member 30.023
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.023
APCSamyloid P component, serum0.022
DCTdopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)0.022
HSD17B2hydroxysteroid (17-beta) dehydrogenase 20.022
SAA4serum amyloid A4, constitutive0.022
APOHapolipoprotein H (beta-2-glycoprotein I)0.022
GYS2glycogen synthase 2 (liver)0.022
MASP1mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)0.021
DDX56DEAD (Asp-Glu-Ala-Asp) box polypeptide 560.021
ZG16zymogen granule protein 16 homolog (rat)0.021
HABP2hyaluronan binding protein 20.020
SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.020
NEDD4neural precursor cell expressed, developmentally down-regulated 40.020
AESamino-terminal enhancer of split0.018
SERPIND1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.018
ELANEelastase, neutrophil expressed0.018
ITIH4inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)0.017
FGL1fibrinogen-like 10.017
LBPlipopolysaccharide binding protein0.017
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.016
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.016
PNLIPpancreatic lipase0.016
ITIH2inter-alpha (globulin) inhibitor H20.016
CTRCchymotrypsin C (caldecrin)0.016
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.016
AGTangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.015
CYP7B1cytochrome P450, family 7, subfamily B, polypeptide 10.015
PNLIPRP1pancreatic lipase-related protein 10.015
C9complement component 90.015
F2coagulation factor II (thrombin)0.015
TDO2tryptophan 2,3-dioxygenase0.014
SERPINA10serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.014
PCK1phosphoenolpyruvate carboxykinase 1 (soluble)0.014
ADHFE1alcohol dehydrogenase, iron containing, 10.014
FGBfibrinogen beta chain0.014
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism