The network for 'positive regulation of homeostatic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of homeostatic process

Any process that activates or increases the frequency, rate, or extent of a homeostatic process.

NameDescriptionProbabilityFunc Analog Organism
IL8interleukin 80.996
CCR5chemokine (C-C motif) receptor 50.900
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.895
CXCL2chemokine (C-X-C motif) ligand 20.884
CREBBPCREB binding protein0.877
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.782
CCL5chemokine (C-C motif) ligand 50.779
BMP2bone morphogenetic protein 20.755
TAL1T-cell acute lymphocytic leukemia 10.727
CXCL3chemokine (C-X-C motif) ligand 30.707
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.703
SMAD2SMAD family member 20.688
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.681
TERF1telomeric repeat binding factor (NIMA-interacting) 10.651
CCL4chemokine (C-C motif) ligand 40.637
CXCL10chemokine (C-X-C motif) ligand 100.619
CXCL9chemokine (C-X-C motif) ligand 90.611
CCL2chemokine (C-C motif) ligand 20.594
HNF4Ahepatocyte nuclear factor 4, alpha0.573
ACVR1Bactivin A receptor, type IB0.508
FKBP1AFK506 binding protein 1A, 12kDa0.505
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.500
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.488
TNFRSF10Btumor necrosis factor receptor superfamily, member 10b0.465
CCL20chemokine (C-C motif) ligand 200.464
SNAP23synaptosomal-associated protein, 23kDa0.443
CXCL5chemokine (C-X-C motif) ligand 50.418
IL6interleukin 6 (interferon, beta 2)0.400
CCR7chemokine (C-C motif) receptor 70.397
IFNGinterferon, gamma0.363
IL1Binterleukin 1, beta0.362
RUNX1runt-related transcription factor 10.357
TGFBR1transforming growth factor, beta receptor 10.354
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.353
CXCL11chemokine (C-X-C motif) ligand 110.340
CCL8chemokine (C-C motif) ligand 80.334
DPP4dipeptidyl-peptidase 40.327
TNFRSF6Btumor necrosis factor receptor superfamily, member 6b, decoy0.322
TERF2IPtelomeric repeat binding factor 2, interacting protein0.316
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.301
HSPA1Bheat shock 70kDa protein 1B0.294
MAPK8mitogen-activated protein kinase 80.288
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.281
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.279
CCL22chemokine (C-C motif) ligand 220.269
ACVR1activin A receptor, type I0.230
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.220
TGFB1transforming growth factor, beta 10.194
HLA-DRB4major histocompatibility complex, class II, DR beta 40.192
FSTL1follistatin-like 10.191
SNAP25synaptosomal-associated protein, 25kDa0.190
ACDadrenocortical dysplasia homolog (mouse)0.188
CCR4chemokine (C-C motif) receptor 40.185
CCL7chemokine (C-C motif) ligand 70.184
DNAJA1DnaJ (Hsp40) homolog, subfamily A, member 10.183
KAT2BK(lysine) acetyltransferase 2B0.182
SH3BP2SH3-domain binding protein 20.180
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.176
CCL3chemokine (C-C motif) ligand 30.176
HSPA1Aheat shock 70kDa protein 1A0.173
ASCC2activating signal cointegrator 1 complex subunit 20.162
ATMataxia telangiectasia mutated0.162
FNBP1formin binding protein 10.156
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.154
SLAMF1signaling lymphocytic activation molecule family member 10.152
CXCL13chemokine (C-X-C motif) ligand 130.149
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.145
CCL19chemokine (C-C motif) ligand 190.144
TLR2toll-like receptor 20.139
TNFAIP6tumor necrosis factor, alpha-induced protein 60.135
TNFRSF10Atumor necrosis factor receptor superfamily, member 10a0.133
MAPTmicrotubule-associated protein tau0.132
ARandrogen receptor0.130
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.124
PTPN6protein tyrosine phosphatase, non-receptor type 60.120
JUNjun proto-oncogene0.118
PLAURplasminogen activator, urokinase receptor0.118
CCL11chemokine (C-C motif) ligand 110.116
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.114
SMAD7SMAD family member 70.114
PTENphosphatase and tensin homolog0.114
ITPR2inositol 1,4,5-trisphosphate receptor, type 20.114
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.109
CAV2caveolin 20.106
FLNBfilamin B, beta0.105
ICAM1intercellular adhesion molecule 10.103
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.103
NR0B2nuclear receptor subfamily 0, group B, member 20.102
CCL13chemokine (C-C motif) ligand 130.100
BAG3BCL2-associated athanogene 30.099
MPDZmultiple PDZ domain protein0.099
HMGB2high mobility group box 20.098
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.096
BCL2A1BCL2-related protein A10.094
PPARGperoxisome proliferator-activated receptor gamma0.093
SOCS3suppressor of cytokine signaling 30.089
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ighimmunoglobulin heavy chain complex0.949
Gata4GATA binding protein 40.676
Cd40CD40 antigen0.646
Mc5rmelanocortin 5 receptor0.603
Ascl1achaete-scute complex homolog 1 (Drosophila)0.585
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.568
Ptf1apancreas specific transcription factor, 1a0.563
Id3inhibitor of DNA binding 30.538
Hand1heart and neural crest derivatives expressed transcript 10.517
Neurod1neurogenic differentiation 10.517
Rxraretinoid X receptor alpha0.485
Eporerythropoietin receptor0.463
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.458
Tcf3transcription factor 30.458
Id1inhibitor of DNA binding 10.458
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.446
Msx1homeobox, msh-like 10.443
Adam12a disintegrin and metallopeptidase domain 12 (meltrin alpha)0.437
Ltblymphotoxin B0.417
WwoxWW domain-containing oxidoreductase0.409
Tcf21transcription factor 210.405
Agtr2angiotensin II receptor, type 20.402
Clec4eC-type lectin domain family 4, member e0.402
Ece1endothelin converting enzyme 10.392
Itgb3integrin beta 30.381
Rargretinoic acid receptor, gamma0.369
Adam19a disintegrin and metallopeptidase domain 19 (meltrin beta)0.368
Pitx3paired-like homeodomain transcription factor 30.366
Acvrl1activin A receptor, type II-like 10.356
Il1binterleukin 1 beta0.351
Ptrfpolymerase I and transcript release factor0.346
Pax9paired box gene 90.339
Vegfavascular endothelial growth factor A0.325
Hic1hypermethylated in cancer 10.323
Ltalymphotoxin A0.320
Ikzf1IKAROS family zinc finger 10.319
Gpr132G protein-coupled receptor 1320.306
Klrb1bkiller cell lectin-like receptor subfamily B member 1B0.302
Nos3nitric oxide synthase 3, endothelial cell0.300
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.291
Tnftumor necrosis factor0.285
Hbb-b1hemoglobin, beta adult major chain0.281
Ltbp2latent transforming growth factor beta binding protein 20.276
S1pr2sphingosine-1-phosphate receptor 20.274
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.266
Mapk14mitogen-activated protein kinase 140.263
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.263
Inhbainhibin beta-A0.252
Agtr1aangiotensin II receptor, type 1a0.251
Prox1prospero-related homeobox 10.248
Gpc3glypican 30.247
Gata1GATA binding protein 10.242
Tal1T-cell acute lymphocytic leukemia 10.241
Ptgs2prostaglandin-endoperoxide synthase 20.237
Mmp9matrix metallopeptidase 90.232
BaxBCL2-associated X protein0.230
Cxcl13chemokine (C-X-C motif) ligand 130.227
Vangl2vang-like 2 (van gogh, Drosophila)0.223
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.221
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.219
Gp9glycoprotein 9 (platelet)0.214
Ccr1chemokine (C-C motif) receptor 10.213
Igkimmunoglobulin kappa chain complex0.210
Anxa5annexin A50.206
Nr3c1nuclear receptor subfamily 3, group C, member 10.206
F2rl2coagulation factor II (thrombin) receptor-like 20.205
Nfe2l2nuclear factor, erythroid derived 2, like 20.204
MecomMDS1 and EVI1 complex locus0.203
Runx1t1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.203
Adam17a disintegrin and metallopeptidase domain 170.202
Bmp7bone morphogenetic protein 70.202
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.200
Adam15a disintegrin and metallopeptidase domain 15 (metargidin)0.189
Hif3ahypoxia inducible factor 3, alpha subunit0.188
Ank1ankyrin 1, erythroid0.185
Nos2nitric oxide synthase 2, inducible0.182
Dmpkdystrophia myotonica-protein kinase0.179
Clec4dC-type lectin domain family 4, member d0.173
Gli2GLI-Kruppel family member GLI20.173
Xcr1chemokine (C motif) receptor 10.173
Lmnalamin A0.173
BtkBruton agammaglobulinemia tyrosine kinase0.172
Gata6GATA binding protein 60.169
C5ar1complement component 5a receptor 10.169
Alox15arachidonate 15-lipoxygenase0.168
Vav2vav 2 oncogene0.163
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.161
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.161
Neurod4neurogenic differentiation 40.158
Mmp12matrix metallopeptidase 120.158
Wt1Wilms tumor 1 homolog0.158
Otx2orthodenticle homolog 2 (Drosophila)0.156
Map3k14mitogen-activated protein kinase kinase kinase 140.153
Clec4a2C-type lectin domain family 4, member a20.152
Rararetinoic acid receptor, alpha0.151
Smc1astructural maintenance of chromosomes 1A0.148
Thbs1thrombospondin 10.148
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Slco2b1solute carrier organic anion transporter family, member 2b10.421
Ccl2chemokine (C-C motif) ligand 20.366
Adora2aadenosine A2a receptor0.357
Stip1stress-induced phosphoprotein 10.207
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.165
Gzmkgranzyme K0.155
Hspa8heat shock protein 80.154
Prol1proline rich, lacrimal 10.140
Hrh2histamine receptor H 20.111
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.110
Ccl4chemokine (C-C motif) ligand 40.102
Olr1278olfactory receptor 12780.093
Kcnj5potassium inwardly-rectifying channel, subfamily J, member 50.093
Olr1641olfactory receptor 16410.090
P2rx2purinergic receptor P2X, ligand-gated ion channel, 20.085
Il1binterleukin 1 beta0.080
Clpscolipase, pancreatic0.077
Csf1colony stimulating factor 1 (macrophage)0.077
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.074
Spp2secreted phosphoprotein 20.074
P2rx3purinergic receptor P2X, ligand-gated ion channel, 30.069
Olr1082olfactory receptor 10820.069
Cd3gCD3 molecule, gamma0.066
Olr1078olfactory receptor 10780.066
Calcrcalcitonin receptor0.064
Nr4a3nuclear receptor subfamily 4, group A, member 30.061
Crhbpcorticotropin releasing hormone binding protein0.059
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.058
Akr1c18aldo-keto reductase family 1, member C180.058
Grin2cglutamate receptor, ionotropic, N-methyl D-aspartate 2C0.057
RGD1310262hypothetical LOC3046500.057
Chrna7cholinergic receptor, nicotinic, alpha 70.050
Il6interleukin 60.049
A1i3alpha-1-inhibitor III0.049
Cpxm2carboxypeptidase X (M14 family), member 20.049
Cxcl13chemokine (C-X-C motif) ligand 130.048
DaoD-amino-acid oxidase0.048
G6pcglucose-6-phosphatase, catalytic subunit0.047
St6galnac3ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 30.046
Prap1proline-rich acidic protein 10.046
Avparginine vasopressin0.045
Folh1folate hydrolase 10.045
Fmr1fragile X mental retardation 10.045
Ifit1interferon-induced protein with tetratricopeptide repeats 10.044
Cxcr5chemokine (C-X-C motif) receptor 50.044
Serpind1serpin peptidase inhibitor, clade D (heparin cofactor), member 10.043
Grm6glutamate receptor, metabotropic 60.043
Hsph1heat shock 105/110 protein 10.043
Foxd3forkhead box D30.043
Hsd17b1hydroxysteroid (17-beta) dehydrogenase 10.043
Grpgastrin releasing peptide0.042
Apoa5apolipoprotein A-V0.042
Calcrlcalcitonin receptor-like0.041
Igfbp3insulin-like growth factor binding protein 30.040
Cd14CD14 molecule0.040
Ppyr1pancreatic polypeptide receptor 10.040
Ngfnerve growth factor (beta polypeptide)0.040
Tbxa2rthromboxane A2 receptor0.040
Marcksmyristoylated alanine rich protein kinase C substrate0.039
Fgf2fibroblast growth factor 20.039
Fshbfollicle stimulating hormone, beta polypeptide0.039
Apba1amyloid beta (A4) precursor protein-binding, family A, member 10.038
Cxcl10chemokine (C-X-C motif) ligand 100.038
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.038
Cyp27b1cytochrome P450, family 27, subfamily b, polypeptide 10.037
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.037
TcrbT-cell receptor beta chain0.037
Agtr1aangiotensin II receptor, type 1a0.037
Xcl1chemokine (C motif) ligand 10.037
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.036
Prf1perforin 1 (pore forming protein)0.036
Klrd1killer cell lectin-like receptor, subfamily D, member 10.036
Scn11asodium channel, voltage-gated, type XI, alpha0.036
Pax6paired box 60.036
LOC679840similar to germinal histone H4 gene0.036
Kcng2potassium voltage-gated channel, subfamily G, member 20.036
Cd247Cd247 molecule0.036
Socs3suppressor of cytokine signaling 30.036
Magmyelin-associated glycoprotein0.036
Olr1500olfactory receptor 15000.035
Atxn1ataxin 10.035
Cxcl11chemokine (C-X-C motif) ligand 110.035
Cckarcholecystokinin A receptor0.035
Apoa4apolipoprotein A-IV0.035
Clec4fC-type lectin domain family 4, member f0.035
Il1rninterleukin 1 receptor antagonist0.034
LOC100362814hypothetical protein LOC1003628140.034
Mmp9matrix metallopeptidase 90.034
Gabrg1gamma-aminobutyric acid (GABA) A receptor, gamma 10.034
Slc22a7solute carrier family 22 (organic anion transporter), member 70.034
Rxrgretinoid X receptor gamma0.034
Avpr1aarginine vasopressin receptor 1A0.034
LOC299282Serine protease inhibitor0.033
Cdh6cadherin 60.033
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism