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Multiple Organisms

linoleic acid metabolic process

The chemical reactions and pathways involving linoleic acid, an unsaturated omega-6 fatty acid that has the molecular formula C18H32O2.

NameDescriptionProbabilityFunc Analog Organism
COTL1coactosin-like 1 (Dictyostelium)1.000
CYP2A6cytochrome P450, family 2, subfamily A, polypeptide 60.946
CYP4A11cytochrome P450, family 4, subfamily A, polypeptide 110.275
OTCornithine carbamoyltransferase0.157
KRT5keratin 50.155
ALOX12Barachidonate 12-lipoxygenase, 12R type0.139
DNAJB9DnaJ (Hsp40) homolog, subfamily B, member 90.138
ADH6alcohol dehydrogenase 6 (class V)0.124
ALOXE3arachidonate lipoxygenase 30.097
TGM1transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase)0.095
CYP2C9cytochrome P450, family 2, subfamily C, polypeptide 90.093
C6complement component 60.086
MAT1Amethionine adenosyltransferase I, alpha0.083
MAST1microtubule associated serine/threonine kinase 10.077
LAMC3laminin, gamma 30.075
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.069
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.066
C8Bcomplement component 8, beta polypeptide0.063
CYP3A4cytochrome P450, family 3, subfamily A, polypeptide 40.063
GLYATglycine-N-acyltransferase0.052
NAT2N-acetyltransferase 2 (arylamine N-acetyltransferase)0.052
SULT1B1sulfotransferase family, cytosolic, 1B, member 10.049
GSTA3glutathione S-transferase alpha 30.046
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.045
CYP2C18cytochrome P450, family 2, subfamily C, polypeptide 180.044
CYP2A7cytochrome P450, family 2, subfamily A, polypeptide 70.044
ALOX5AParachidonate 5-lipoxygenase-activating protein0.044
AADACarylacetamide deacetylase (esterase)0.043
CYP2B6cytochrome P450, family 2, subfamily B, polypeptide 60.042
SLC10A1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.041
RIT1Ras-like without CAAX 10.040
SLC2A2solute carrier family 2 (facilitated glucose transporter), member 20.040
AGXT2alanine--glyoxylate aminotransferase 20.040
HRGhistidine-rich glycoprotein0.038
GPLD1glycosylphosphatidylinositol specific phospholipase D10.038
ALDOBaldolase B, fructose-bisphosphate0.038
KLK13kallikrein-related peptidase 130.037
FMO4flavin containing monooxygenase 40.037
CYP2C19cytochrome P450, family 2, subfamily C, polypeptide 190.036
BHMTbetaine--homocysteine S-methyltransferase0.035
CPEB4cytoplasmic polyadenylation element binding protein 40.032
CFHR4complement factor H-related 40.031
CYP1A2cytochrome P450, family 1, subfamily A, polypeptide 20.031
HMGCS23-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)0.031
FETUBfetuin B0.030
GATMglycine amidinotransferase (L-arginine:glycine amidinotransferase)0.029
CYP2C8cytochrome P450, family 2, subfamily C, polypeptide 80.028
ITIH4inter-alpha (globulin) inhibitor H4 (plasma Kallikrein-sensitive glycoprotein)0.027
GNA13guanine nucleotide binding protein (G protein), alpha 130.027
HBP1HMG-box transcription factor 10.027
HALhistidine ammonia-lyase0.027
MTTPmicrosomal triglyceride transfer protein0.026
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.026
SULT2B1sulfotransferase family, cytosolic, 2B, member 10.025
GBA3glucosidase, beta, acid 3 (cytosolic)0.025
C4BPAcomplement component 4 binding protein, alpha0.025
F9coagulation factor IX0.024
ACRV1acrosomal vesicle protein 10.023
CYP2D6cytochrome P450, family 2, subfamily D, polypeptide 60.023
MUC3Amucin 3A, cell surface associated0.023
AFMafamin0.023
DYNLT3dynein, light chain, Tctex-type 30.022
TBC1D23TBC1 domain family, member 230.022
CYP3A5cytochrome P450, family 3, subfamily A, polypeptide 50.022
G6PCglucose-6-phosphatase, catalytic subunit0.022
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.022
RNF32ring finger protein 320.021
CYP2E1cytochrome P450, family 2, subfamily E, polypeptide 10.021
XDHxanthine dehydrogenase0.021
IFRD1interferon-related developmental regulator 10.020
HPXhemopexin0.019
F11coagulation factor XI0.019
SLC22A1solute carrier family 22 (organic cation transporter), member 10.019
CCL16chemokine (C-C motif) ligand 160.019
SGK2serum/glucocorticoid regulated kinase 20.018
SULT2A1sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 10.018
ANXA10annexin A100.018
GYS2glycogen synthase 2 (liver)0.018
F13Bcoagulation factor XIII, B polypeptide0.018
JHDM1Djumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)0.018
BAATbile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)0.018
PIGAphosphatidylinositol glycan anchor biosynthesis, class A0.017
ABCC2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.017
CYP7A1cytochrome P450, family 7, subfamily A, polypeptide 10.017
DPYSdihydropyrimidinase0.017
CYP1A1cytochrome P450, family 1, subfamily A, polypeptide 10.017
HGDhomogentisate 1,2-dioxygenase0.017
CA5Acarbonic anhydrase VA, mitochondrial0.016
CSGALNACT2chondroitin sulfate N-acetylgalactosaminyltransferase 20.016
CNGA1cyclic nucleotide gated channel alpha 10.016
HABP2hyaluronan binding protein 20.016
MPP3membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)0.016
HPD4-hydroxyphenylpyruvate dioxygenase0.016
KRT4keratin 40.016
FABP1fatty acid binding protein 1, liver0.016
CYP4F11cytochrome P450, family 4, subfamily F, polypeptide 110.016
MEP1Bmeprin A, beta0.016
TTPAtocopherol (alpha) transfer protein0.016
DUOX2dual oxidase 20.016
C8Acomplement component 8, alpha polypeptide0.016
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cyp2c38cytochrome P450, family 2, subfamily c, polypeptide 380.946
Cyp2c29cytochrome P450, family 2, subfamily c, polypeptide 290.834
Cyp3a11cytochrome P450, family 3, subfamily a, polypeptide 110.764
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.692
Cps1carbamoyl-phosphate synthetase 10.542
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.448
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.419
Cyp2c54cytochrome P450, family 2, subfamily c, polypeptide 540.255
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.234
Cyp2b9cytochrome P450, family 2, subfamily b, polypeptide 90.210
Sult1d1sulfotransferase family 1D, member 10.194
CrpC-reactive protein, pentraxin-related0.176
Otcornithine transcarbamylase0.163
Aadacarylacetamide deacetylase (esterase)0.154
Cyp2c39cytochrome P450, family 2, subfamily c, polypeptide 390.151
Keg1kidney expressed gene 10.148
Krtap6-1keratin associated protein 6-10.127
Nr1i2nuclear receptor subfamily 1, group I, member 20.119
Akr1c6aldo-keto reductase family 1, member C60.115
Cyp2c68cytochrome P450, family 2, subfamily c, polypeptide 680.113
Sult1b1sulfotransferase family 1B, member 10.108
Cyp2c50cytochrome P450, family 2, subfamily c, polypeptide 500.101
Casp14caspase 140.091
Ugt2a3UDP glucuronosyltransferase 2 family, polypeptide A30.091
Slco1b2solute carrier organic anion transporter family, member 1b20.085
F9coagulation factor IX0.075
Ugt3a2UDP glycosyltransferases 3 family, polypeptide A20.068
Azgp1alpha-2-glycoprotein 1, zinc0.067
Pigrpolymeric immunoglobulin receptor0.066
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.066
Cyp2a12cytochrome P450, family 2, subfamily a, polypeptide 120.064
Hsd3b2hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 20.063
Akr1d1aldo-keto reductase family 1, member D10.062
Ces2acarboxylesterase 2A0.062
Cml2camello-like 20.060
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.056
Mup5major urinary protein 50.056
Cyp2b19cytochrome P450, family 2, subfamily b, polypeptide 190.054
Pon1paraoxonase 10.049
Cyp2b13cytochrome P450, family 2, subfamily b, polypeptide 130.046
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.046
Hrghistidine-rich glycoprotein0.045
Cfhr1complement factor H-related 10.044
Ly6g6clymphocyte antigen 6 complex, locus G6C0.044
Ces1ccarboxylesterase 1C0.042
G6pcglucose-6-phosphatase, catalytic0.041
Cyp4a14cytochrome P450, family 4, subfamily a, polypeptide 140.040
Tdo2tryptophan 2,3-dioxygenase0.040
Cyp2c37cytochrome P450, family 2. subfamily c, polypeptide 370.039
Mup3major urinary protein 30.038
Pplperiplakin0.037
Hsd3b3hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 30.037
Apoc4apolipoprotein C-IV0.036
Aldobaldolase B, fructose-bisphosphate0.035
Bchebutyrylcholinesterase0.035
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.034
Hsd3b5hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 50.033
Serpina1cserine (or cysteine) peptidase inhibitor, clade A, member 1C0.031
Cyp2g1cytochrome P450, family 2, subfamily g, polypeptide 10.030
Csn1s1casein alpha s10.030
Tattyrosine aminotransferase0.029
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.028
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.028
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.028
Slc22a18solute carrier family 22 (organic cation transporter), member 180.027
Apoc3apolipoprotein C-III0.026
Adamdec1ADAM-like, decysin 10.026
Slc22a1solute carrier family 22 (organic cation transporter), member 10.025
F2coagulation factor II0.025
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.025
Adh7alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide0.025
Cyp2d9cytochrome P450, family 2, subfamily d, polypeptide 90.025
Slco1a1solute carrier organic anion transporter family, member 1a10.025
Lect2leukocyte cell-derived chemotaxin 20.024
Apcsserum amyloid P-component0.024
Pklrpyruvate kinase liver and red blood cell0.023
Cyp2f2cytochrome P450, family 2, subfamily f, polypeptide 20.023
Baatbile acid-Coenzyme A: amino acid N-acyltransferase0.022
Serpinb5serine (or cysteine) peptidase inhibitor, clade B, member 50.022
Ces1dcarboxylesterase 1D0.022
Krt6bkeratin 6B0.022
Chadchondroadherin0.022
Mocs1molybdenum cofactor synthesis 10.022
Vsig4V-set and immunoglobulin domain containing 40.021
Tmprss15transmembrane protease, serine 150.021
Prss32protease, serine, 320.021
Aldh3a1aldehyde dehydrogenase family 3, subfamily A10.021
Inmtindolethylamine N-methyltransferase0.021
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.020
Dpysdihydropyrimidinase0.020
Mbl1mannose-binding lectin (protein A) 10.020
Rdh7retinol dehydrogenase 70.020
Defb1defensin beta 10.019
Upp2uridine phosphorylase 20.018
Cfhr2complement factor H-related 20.018
Lipclipase, hepatic0.018
Cyp3a44cytochrome P450, family 3, subfamily a, polypeptide 440.018
Fmo1flavin containing monooxygenase 10.018
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.018
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.017
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Cyp2d4cytochrome P450, family 2, subfamily d, polypeptide 40.970
Cyp1a1cytochrome P450, family 1, subfamily a, polypeptide 10.850
Cyp2b1cytochrome P450, family 2, subfamily b, polypeptide 10.832
Sult1b1sulfotransferase family, cytosolic, 1B, member 10.763
Cyp4f1cytochrome P450, family 4, subfamily f, polypeptide 10.698
Cyp3a18cytochrome P450, family 3, subfamily a, polypeptide 180.679
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.580
Apobapolipoprotein B0.576
Cyp2a1cytochrome P450, family 2, subfamily a, polypeptide 10.496
Dnase1deoxyribonuclease I0.486
Cyp2e1cytochrome P450, family 2, subfamily e, polypeptide 10.466
Mosc1MOCO sulphurase C-terminal domain containing 10.461
Ugt2b1UDP glucuronosyltransferase 2 family, polypeptide B10.417
Cyp4a3cytochrome P450, family 4, subfamily a, polypeptide 30.382
Cyp4a10cytochrome P450, family 4, subfamily a, polypeptide 100.347
Cyp3a9cytochrome P450, family 3, subfamily a, polypeptide 90.279
Ehhadhenoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase0.266
Slc23a1solute carrier family 23 (nucleobase transporters), member 10.263
Mettl7bmethyltransferase like 7B0.236
Cyp2a2cytochrome P450, family 2, subfamily a, polypeptide 20.221
Cyp2d3cytochrome P450, family 2, subfamily d, polypeptide 30.219
Akr1c18aldo-keto reductase family 1, member C180.203
LOC100365112carboxylesterase-like0.193
Cyp2b2cytochrome P450, family 2, subfamily b, polypeptide 20.179
Cyp2d1cytochrome P450, family 2, subfamily d, polypeptide 10.167
Ugt2b5UDP glucuronosyltransferase 2 family, polypeptide B50.146
Cyp2c13cytochrome P450, family 2, subfamily c, polypeptide 130.138
Sult1e1sulfotransferase family 1E, estrogen-preferring, member 10.134
Dpep1dipeptidase 1 (renal)0.128
Abcb11ATP-binding cassette, subfamily B (MDR/TAP), member 110.126
Cyp2c23cytochrome P450, family 2, subfamily c, polypeptide 230.115
Slco1a1solute carrier organic anion transporter family, member 1a10.101
Cyp4a2cytochrome P450, family 4, subfamily a, polypeptide 20.098
Cyp17a1cytochrome P450, family 17, subfamily a, polypeptide 10.090
Cyp2c11cytochrome P450, subfamily 2, polypeptide 110.088
Acsm2acyl-CoA synthetase medium-chain family member 20.085
Pbldphenazine biosynthesis-like protein domain containing0.084
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.080
Rxrgretinoid X receptor gamma0.071
Akr1c14aldo-keto reductase family 1, member C140.069
Fmo1flavin containing monooxygenase 10.067
LOC494499LOC494499 protein0.066
Cyp2b15cytochrome P450, family 2, subfamily b, polypeptide 150.066
LOC293989cytochrome P450-like0.061
Olr37olfactory receptor 370.061
Adh1alcohol dehydrogenase 1 (class I)0.060
Vom2r50vomeronasal 2 receptor, 500.059
Acot2acyl-CoA thioesterase 20.056
Aqp9aquaporin 90.055
Slco1b3solute carrier organic anion transporter family, member 1b30.053
Afmafamin0.052
Cyp2j3cytochrome P450, family 2, subfamily j, polypeptide 30.049
Sult1c2sulfotransferase family, cytosolic, 1C, member 20.048
Cyp27a1cytochrome P450, family 27, subfamily a, polypeptide 10.047
Fdxrferredoxin reductase0.046
Slc22a7solute carrier family 22 (organic anion transporter), member 70.045
DaoD-amino-acid oxidase0.043
Gsta2glutathione S-transferase A20.041
Ces2ccarboxylesterase 2C0.041
Hmgcs23-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial)0.041
Qpctglutaminyl-peptide cyclotransferase0.041
Nmuneuromedin U0.039
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.038
Pex11aperoxisomal biogenesis factor 11 alpha0.037
Pax6paired box 60.035
Dpp4dipeptidylpeptidase 40.035
RGD1308772similar to KIAA0564 protein0.034
Crygfcrystallin, gamma F0.034
Gzmbgranzyme B0.034
Cyp2j4cytochrome P450, family 2, subfamily j, polypeptide 40.033
Slco1a4solute carrier organic anion transporter family, member 1a40.033
Cyp2f4cytochrome P450, family 2, subfamily f, polypeptide 40.032
Fabp1fatty acid binding protein 1, liver0.032
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.031
Cyp3a23/3a1cytochrome P450, family 3, subfamily a, polypeptide 23/polypeptide 10.031
Ugt2b7UDP glucuronosyltransferase 2 family, polypeptide B70.031
Olr1701olfactory receptor 17010.030
Acot12acyl-CoA thioesterase 120.030
Srd5a1steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)0.030
Gpr116G protein-coupled receptor 1160.030
Acadsacyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain0.029
Retsatretinol saturase (all trans retinol 13,14 reductase)0.029
Olr1697olfactory receptor 16970.028
Cyp4b1cytochrome P450, family 4, subfamily b, polypeptide 10.027
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.026
Gckrglucokinase (hexokinase 4) regulator0.025
Ces1ccarboxylesterase 1C0.025
As3mtarsenic (+3 oxidation state) methyltransferase0.024
Tcea3transcription elongation factor A (SII), 30.024
Fgbfibrinogen beta chain0.024
Dpyddihydropyrimidine dehydrogenase0.023
Efcab4aEF-hand calcium binding domain 4A0.022
Thnsl2threonine synthase-like 2 (S. cerevisiae)0.022
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.022
Cyp4f6cytochrome P450, family 4, subfamily f, polypeptide 60.021
Rup2urinary protein 20.021
Il15interleukin 150.020
Sult1a1sulfotransferase family, cytosolic, 1A, phenol-preferring, member 10.020
Cyp7a1cytochrome P450, family 7, subfamily a, polypeptide 10.020
Abp10annexin V-binding protein ABP-100.020
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism