The network for 'carbohydrate catabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

carbohydrate catabolic process

The chemical reactions and pathways resulting in the breakdown of carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y.

NameDescriptionProbabilityFunc Analog Organism
ALDOAaldolase A, fructose-bisphosphate0.992
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.988
ENO1enolase 1, (alpha)0.977
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.943
TPI1triosephosphate isomerase 10.929
PKM2pyruvate kinase, muscle0.922
GPIglucose-6-phosphate isomerase0.910
LDHAlactate dehydrogenase A0.905
TKTtransketolase0.887
NCOR2nuclear receptor corepressor 20.790
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.764
PGK1phosphoglycerate kinase 10.753
GLB1galactosidase, beta 10.728
SIN3ASIN3 homolog A, transcription regulator (yeast)0.565
HK1hexokinase 10.558
CTSAcathepsin A0.497
ENO2enolase 2 (gamma, neuronal)0.427
NCOR1nuclear receptor corepressor 10.421
EGFRepidermal growth factor receptor0.368
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)0.320
GRNgranulin0.311
SMARCC1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 10.299
PGAM1phosphoglycerate mutase 1 (brain)0.284
PTPN1protein tyrosine phosphatase, non-receptor type 10.281
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.258
GRB10growth factor receptor-bound protein 100.236
PPARAperoxisome proliferator-activated receptor alpha0.231
PPP1R9Bprotein phosphatase 1, regulatory (inhibitor) subunit 9B0.220
IRS1insulin receptor substrate 10.216
TALDO1transaldolase 10.214
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.212
HNF4Ahepatocyte nuclear factor 4, alpha0.186
ARID1BAT rich interactive domain 1B (SWI1-like)0.179
NEU1sialidase 1 (lysosomal sialidase)0.176
GYS1glycogen synthase 1 (muscle)0.165
PFKLphosphofructokinase, liver0.161
BBS1Bardet-Biedl syndrome 10.158
ITGB1BP3integrin beta 1 binding protein 30.144
TPP1tripeptidyl peptidase I0.143
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.139
IGF2Rinsulin-like growth factor 2 receptor0.137
PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.129
DDOSTdolichyl-diphosphooligosaccharide--protein glycosyltransferase0.112
PPP1R2protein phosphatase 1, regulatory (inhibitor) subunit 20.111
RXRAretinoid X receptor, alpha0.104
PPP1CAprotein phosphatase 1, catalytic subunit, alpha isozyme0.100
ARID1AAT rich interactive domain 1A (SWI-like)0.096
PLOD1procollagen-lysine 1, 2-oxoglutarate 5-dioxygenase 10.094
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.086
RNPEParginyl aminopeptidase (aminopeptidase B)0.077
PTPRZ1protein tyrosine phosphatase, receptor-type, Z polypeptide 10.072
TUBA4Atubulin, alpha 4a0.070
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.066
FCN2ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)0.064
RARAretinoic acid receptor, alpha0.060
CAV1caveolin 1, caveolae protein, 22kDa0.057
CTSDcathepsin D0.056
PFKFB16-phosphofructo-2-kinase/fructose-2,6-biphosphatase 10.054
ESR1estrogen receptor 10.054
MAP4microtubule-associated protein 40.053
ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 10.052
GCKRglucokinase (hexokinase 4) regulator0.049
SMAD9SMAD family member 90.048
CCND1cyclin D10.048
P4HBprolyl 4-hydroxylase, beta polypeptide0.048
DDB1damage-specific DNA binding protein 1, 127kDa0.047
GPD1glycerol-3-phosphate dehydrogenase 1 (soluble)0.045
PGDphosphogluconate dehydrogenase0.044
IRS2insulin receptor substrate 20.043
SLC16A3solute carrier family 16, member 3 (monocarboxylic acid transporter 4)0.043
PTNpleiotrophin0.043
FBP2fructose-1,6-bisphosphatase 20.042
CAPRIN2caprin family member 20.041
FAF1Fas (TNFRSF6) associated factor 10.041
PLD3phospholipase D family, member 30.041
CAPNS1calpain, small subunit 10.040
LAMP1lysosomal-associated membrane protein 10.040
HSPB1heat shock 27kDa protein 10.039
EPM2Aepilepsy, progressive myoclonus type 2A, Lafora disease (laforin)0.038
GHRgrowth hormone receptor0.038
G6PDglucose-6-phosphate dehydrogenase0.037
BCL6B-cell CLL/lymphoma 60.037
HRhairless homolog (mouse)0.036
PRKCSHprotein kinase C substrate 80K-H0.036
AP2M1adaptor-related protein complex 2, mu 1 subunit0.036
PGRprogesterone receptor0.036
MLXMAX-like protein X0.035
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.035
ESRRGestrogen-related receptor gamma0.035
YWHAEtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.035
CLN3ceroid-lipofuscinosis, neuronal 30.034
NCOA1nuclear receptor coactivator 10.033
ALDOCaldolase C, fructose-bisphosphate0.033
VEGFAvascular endothelial growth factor A0.033
MEF2Amyocyte enhancer factor 2A0.033
MAN2B1mannosidase, alpha, class 2B, member 10.033
PFKPphosphofructokinase, platelet0.032
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.031
EGLN3egl nine homolog 3 (C. elegans)0.031
DKK1dickkopf homolog 1 (Xenopus laevis)0.031
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PgkPhosphoglycerate kinase0.641
PyKPyruvate kinase0.452
EnoEnolase0.451
LvpHLarval visceral protein H0.160
PgdPhosphogluconate dehydrogenase0.147
scylscylla0.116
CG4363CG4363 gene product from transcript CG4363-RA0.112
CG4377CG4377 gene product from transcript CG4377-RA0.085
ArgkArginine kinase0.078
PgiPhosphoglucose isomerase0.076
TpiTriose phosphate isomerase0.073
CG33138CG33138 gene product from transcript CG33138-RA0.073
CG8690CG8690 gene product from transcript CG8690-RA0.072
Pglym78Phosphoglyceromutase0.072
PgmPhosphogluconate mutase0.068
AdhAlcohol dehydrogenase0.059
CG6283CG6283 gene product from transcript CG6283-RA0.045
Got2Glutamate oxaloacetate transaminase 20.044
MntCG13316 gene product from transcript CG13316-RD0.044
LvpDLarval visceral protein D0.043
ThorCG8846 gene product from transcript CG8846-RA0.036
ryrosy0.033
CG6484CG6484 gene product from transcript CG6484-RA0.033
CG9468CG9468 gene product from transcript CG9468-RA0.029
Gapdh2Glyceraldehyde 3 phosphate dehydrogenase 20.028
CG3739CG3739 gene product from transcript CG3739-RA0.028
ImpL3Ecdysone-inducible gene L30.027
CG30360CG30360 gene product from transcript CG30360-RC0.027
Gapdh1Glyceraldehyde 3 phosphate dehydrogenase 10.023
CG14204CG14204 gene product from transcript CG14204-RA0.021
CG10750CG10750 gene product from transcript CG10750-RA0.021
Trxr-1Thioredoxin reductase-10.019
CG11669CG11669 gene product from transcript CG11669-RA0.019
CG9014CG9014 gene product from transcript CG9014-RA0.015
CG13474CG13474 gene product from transcript CG13474-RA0.014
ImpL2Ecdysone-inducible gene L20.014
GlyPGlycogen phosphorylase0.014
CG7998CG7998 gene product from transcript CG7998-RA0.013
CG9466CG9466 gene product from transcript CG9466-RA0.013
Mp20Muscle protein 200.013
CG5362CG5362 gene product from transcript CG5362-RA0.012
IlkIntegrin linked kinase0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Aldoaaldolase A, fructose-bisphosphate1.000
Pkm2pyruvate kinase, muscle1.000
Ldhalactate dehydrogenase A1.000
Gpi1glucose phosphate isomerase 10.993
Tpi1triosephosphate isomerase 10.989
Gm5506predicted gene 55060.988
Pfklphosphofructokinase, liver, B-type0.981
Mef2dmyocyte enhancer factor 2D0.980
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.973
Leprleptin receptor0.966
Stat5bsignal transducer and activator of transcription 5B0.937
Adrb1adrenergic receptor, beta 10.909
Pnpla2patatin-like phospholipase domain containing 20.882
Hexahexosaminidase A0.831
Irf9interferon regulatory factor 90.799
Stat5asignal transducer and activator of transcription 5A0.759
Pgam1phosphoglycerate mutase 10.711
Ppargperoxisome proliferator activated receptor gamma0.646
Pgk1phosphoglycerate kinase 10.575
Hexbhexosaminidase B0.523
Nr3c1nuclear receptor subfamily 3, group C, member 10.434
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.417
Vegfbvascular endothelial growth factor B0.400
Pgdphosphogluconate dehydrogenase0.394
Klklotho0.361
Drd2dopamine receptor D20.361
Egln1EGL nine homolog 1 (C. elegans)0.332
Insrinsulin receptor0.304
Arid1bAT rich interactive domain 1B (SWI-like)0.302
Bsgbasigin0.292
Thrathyroid hormone receptor alpha0.277
Tkttransketolase0.274
Runx2runt related transcription factor 20.262
Lepleptin0.258
Hbb-b1hemoglobin, beta adult major chain0.235
Hsd3b7hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 70.223
Ghrgrowth hormone receptor0.220
Gys1glycogen synthase 1, muscle0.215
Pygmmuscle glycogen phosphorylase0.213
Kcnk3potassium channel, subfamily K, member 30.200
Atp4aATPase, H+/K+ exchanging, gastric, alpha polypeptide0.194
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.189
Mef2cmyocyte enhancer factor 2C0.187
Slc2a1solute carrier family 2 (facilitated glucose transporter), member 10.185
Hnf4ahepatic nuclear factor 4, alpha0.175
Hdac5histone deacetylase 50.173
Taldo1transaldolase 10.155
Vdrvitamin D receptor0.152
Prlrprolactin receptor0.151
Sp3trans-acting transcription factor 30.147
MaxMax protein0.145
Gusbglucuronidase, beta0.142
Cckbrcholecystokinin B receptor0.140
Iduaiduronidase, alpha-L-0.138
Stat3signal transducer and activator of transcription 30.137
Prkacaprotein kinase, cAMP dependent, catalytic, alpha0.129
Smad3MAD homolog 3 (Drosophila)0.127
Mas1MAS1 oncogene0.124
Tgfbr3transforming growth factor, beta receptor III0.124
Otporthopedia homolog (Drosophila)0.123
Apoa1apolipoprotein A-I0.121
Esr1estrogen receptor 1 (alpha)0.120
Bhlhe40basic helix-loop-helix family, member e400.119
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.118
Prelid1PRELI domain containing 10.115
Lhx6LIM homeobox protein 60.108
Adrb2adrenergic receptor, beta 20.106
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.103
Slc12a1solute carrier family 12, member 10.101
Thrbthyroid hormone receptor beta0.098
Ctsdcathepsin D0.097
Coro1bcoronin, actin binding protein 1B0.097
Pparaperoxisome proliferator activated receptor alpha0.094
Hdac4histone deacetylase 40.092
Npc2Niemann Pick type C20.091
Snta1syntrophin, acidic 10.091
Sstr4somatostatin receptor 40.090
Egln3EGL nine homolog 3 (C. elegans)0.090
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.089
Kcna4potassium voltage-gated channel, shaker-related subfamily, member 40.088
Adra1aadrenergic receptor, alpha 1a0.085
Apobapolipoprotein B0.084
Arnt2aryl hydrocarbon receptor nuclear translocator 20.080
Plcg1phospholipase C, gamma 10.078
Adra1badrenergic receptor, alpha 1b0.077
Acsl1acyl-CoA synthetase long-chain family member 10.076
Npy1rneuropeptide Y receptor Y10.074
Myd88myeloid differentiation primary response gene 880.074
Npy2rneuropeptide Y receptor Y20.074
Il4rainterleukin 4 receptor, alpha0.073
Grm2glutamate receptor, metabotropic 20.073
Axin1axin 10.072
Tattyrosine aminotransferase0.071
Clcnkachloride channel Ka0.071
Il5interleukin 50.069
Adcy6adenylate cyclase 60.069
Arid1aAT rich interactive domain 1A (SWI-like)0.069
Nos1nitric oxide synthase 1, neuronal0.067
D4Wsu53eDNA segment, Chr 4, Wayne State University 53, expressed0.066
Ckmt2creatine kinase, mitochondrial 20.066
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Eno1enolase 1, (alpha)1.000
Pkm2pyruvate kinase, muscle1.000
Gapdhglyceraldehyde-3-phosphate dehydrogenase1.000
Aldoaaldolase A, fructose-bisphosphate1.000
Tpi1triosephosphate isomerase 11.000
Ldhalactate dehydrogenase A0.999
Gpiglucose phosphate isomerase0.999
Mifmacrophage migration inhibitory factor0.999
Pgam1phosphoglycerate mutase 1 (brain)0.997
Pgk1phosphoglycerate kinase 10.977
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.713
Pebp1phosphatidylethanolamine binding protein 10.711
Pdk2pyruvate dehydrogenase kinase, isozyme 20.535
LOC1003636626-phosphogluconate dehydrogenase, decarboxylating-like0.367
Tkttransketolase0.359
Atp6v0cATPase, H+ transporting, lysosomal V0 subunit C0.283
Vdac1voltage-dependent anion channel 10.219
Ndrg2N-myc downstream regulated gene 20.218
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.215
Cyp4a8cytochrome P450, family 4, subfamily a, polypeptide 80.213
Tecrtrans-2,3-enoyl-CoA reductase0.212
Gcgrglucagon receptor0.189
Pfkmphosphofructokinase, muscle0.189
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.188
Phkg1phosphorylase kinase, gamma 10.163
Pfklphosphofructokinase, liver0.159
Tstthiosulfate sulfurtransferase0.150
Akap1A kinase (PRKA) anchor protein 10.149
Ncanneurocan0.124
Gipgastric inhibitory polypeptide0.123
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.110
Bsgbasigin0.105
Pgm1phosphoglucomutase 10.104
Rpl3lribosomal protein L3-like0.102
Bcat1branched chain aminotransferase 1, cytosolic0.097
LOC686590similar to IQ motif and Sec7 domain 10.094
Adam7ADAM metallopeptidase domain 70.092
Tubg1tubulin, gamma 10.089
Rxrgretinoid X receptor gamma0.084
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.084
Pgam2phosphoglycerate mutase 2 (muscle)0.080
Pdk1pyruvate dehydrogenase kinase, isozyme 10.079
Snx2sorting nexin 20.077
Dakdihydroxyacetone kinase 2 homolog (S. cerevisiae)0.074
Stxbp1syntaxin binding protein 10.070
G6pdglucose-6-phosphate dehydrogenase0.070
Darsaspartyl-tRNA synthetase0.069
Akp3alkaline phosphatase 3, intestine, not Mn requiring0.065
Ywhagtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.064
Grifingalectin-related inter-fiber protein0.064
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.064
Fgf14fibroblast growth factor 140.064
Fkbp4FK506 binding protein 40.062
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.061
Dckdeoxycytidine kinase0.060
Pcsk1proprotein convertase subtilisin/kexin type 10.058
Cfl1cofilin 1, non-muscle0.057
Cmtm6CKLF-like MARVEL transmembrane domain containing 60.057
Aprtadenine phosphoribosyl transferase0.056
Aco2aconitase 2, mitochondrial0.054
PorP450 (cytochrome) oxidoreductase0.054
Ak1adenylate kinase 10.053
Arandrogen receptor0.053
Muc3amucin 3A, cell surface associated0.052
Capns1calpain, small subunit 10.052
Slc25a4solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 40.052
Ctsbcathepsin B0.051
Acsl1acyl-CoA synthetase long-chain family member 10.051
Guca2aguanylate cyclase activator 2a (guanylin)0.051
TufmTu translation elongation factor, mitochondrial0.051
Ugt2a1UDP glucuronosyltransferase 2 family, polypeptide A10.050
Pfkpphosphofructokinase, platelet0.050
Foxe3forkhead box E30.050
Hpcal4hippocalcin-like 40.050
Dnpepaspartyl aminopeptidase0.050
Nr1i2nuclear receptor subfamily 1, group I, member 20.050
GnasGNAS complex locus0.049
Rilreversion induced LIM gene0.048
Eno3enolase 3, beta, muscle0.048
Sycnsyncollin0.048
Clip2CAP-GLY domain containing linker protein 20.047
Atxn10ataxin 100.047
Aldh7a1aldehyde dehydrogenase 7 family, member A10.046
Fabp5fatty acid binding protein 5, epidermal0.045
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.044
Lypla1lysophospholipase 10.044
LOC100366119Mpv17 transgene, kidney disease mutant-like (predicted)-like0.043
Ldhblactate dehydrogenase B0.043
Abp10annexin V-binding protein ABP-100.043
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.042
Esr1estrogen receptor 10.041
Cdh17cadherin 170.041
Fitm1fat storage-inducing transmembrane protein 10.041
Cdk4cyclin-dependent kinase 40.041
Karslysyl-tRNA synthetase0.040
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.040
Fam126bfamily with sequence similarity 126, member B0.040
Cyp11a1cytochrome P450, family 11, subfamily a, polypeptide 10.039
Il1r1interleukin 1 receptor, type I0.039
Slc7a2solute carrier family 7 (cationic amino acid transporter, y+ system), member 20.039
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
FBA1Fba1p0.999
ADH1Adh1p0.991
GND1Gnd1p0.978
PDC1Pdc1p0.977
PGK1Pgk1p0.977
GPM1Gpm1p0.972
ENO2Eno2p0.959
PGI1Pgi1p0.957
MAL32Mal32p0.925
TDH2Tdh2p0.907
ENO1Eno1p0.905
MAL11Mal11p0.891
GSY2Gsy2p0.863
HXK2Hxk2p0.846
TDH3Tdh3p0.771
PFK1Pfk1p0.676
TPI1Tpi1p0.595
SNF5Snf5p0.582
IMA1Ima1p0.579
GND2Gnd2p0.577
GAL4Gal4p0.568
SWI3Swi3p0.520
SWI1Swi1p0.503
GAL2Gal2p0.501
ADH3Adh3p0.467
REG1Reg1p0.464
IMA2Ima2p0.455
SDS24Sds24p0.447
HXT9Hxt9p0.421
TAL1Tal1p0.408
NQM1Nqm1p0.402
GAL10Gal10p0.377
PFK2Pfk2p0.366
GRE3Gre3p0.364
YMR315Whypothetical protein0.342
GAL7Gal7p0.341
HOR2Hor2p0.321
ERR3Err3p0.320
MVD1Mvd1p0.319
ERR1Err1p0.310
ARP7Arp7p0.293
CDC19Cdc19p0.291
UGP1Ugp1p0.290
IMA4Ima4p0.288
GDB1Gdb1p0.281
SNF2Snf2p0.277
SNF12Snf12p0.273
ERR2Err2p0.273
MAL12Mal12p0.253
SPE3Spe3p0.247
GPM2Gpm2p0.245
SAP4Sap4p0.237
ALD6Ald6p0.215
YNR073Chypothetical protein0.215
GAL1Gal1p0.208
BNA5Bna5p0.203
HBT1Hbt1p0.196
IMA3Ima3p0.195
YLR345Whypothetical protein0.191
SOL1Sol1p0.189
GAL3Gal3p0.172
TKL2Tkl2p0.172
YHR138Chypothetical protein0.171
FYV10Fyv10p0.170
PDR3Pdr3p0.166
DOG2Dog2p0.159
RRD1Rrd1p0.157
YKL151Chypothetical protein0.146
YBR013Chypothetical protein0.144
HOM6Hom6p0.142
FLO8Flo8p0.139
ARO1Aro1p0.138
YFR017Chypothetical protein0.137
GAL83Gal83p0.134
ECM4Ecm4p0.134
GLN1Gln1p0.133
ALD4Ald4p0.132
PHO85Pho85p0.131
MPH3Mph3p0.130
ADH2Adh2p0.129
GPD2Gpd2p0.126
PET9Pet9p0.123
GIP2Gip2p0.120
SUI2Sui2p0.119
GUT2Gut2p0.117
PRD1Prd1p0.117
TRR1Trr1p0.116
GIS1Gis1p0.113
EMI2Emi2p0.112
ASM4Asm4p0.112
PCL6Pcl6p0.111
TPK1Tpk1p0.110
SWP82Swp82p0.109
YDL218Whypothetical protein0.108
XKS1Xks1p0.108
YDL124Whypothetical protein0.107
CAK1Cak1p0.107
URN1Urn1p0.105
HXK1Hxk1p0.104
PHM7Phm7p0.102