The network for 'regulation of hemostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of hemostasis

Any process that modulates the frequency, rate or extent of hemostasis.

NameDescriptionProbabilityFunc Analog Organism
SYKspleen tyrosine kinase0.996
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.989
C1QAcomplement component 1, q subcomponent, A chain0.988
PLCG1phospholipase C, gamma 10.977
EGFRepidermal growth factor receptor0.975
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.959
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.953
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.792
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.771
PTENphosphatase and tensin homolog0.743
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.725
C1QBcomplement component 1, q subcomponent, B chain0.721
VEGFAvascular endothelial growth factor A0.666
SNAP23synaptosomal-associated protein, 23kDa0.653
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.639
NCF1neutrophil cytosolic factor 10.635
CAV1caveolin 1, caveolae protein, 22kDa0.629
NRP1neuropilin 10.575
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.498
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.438
ZNF746zinc finger protein 7460.394
PLAUplasminogen activator, urokinase0.388
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.374
FYBFYN binding protein0.338
SH3BP2SH3-domain binding protein 20.324
VAMP3vesicle-associated membrane protein 3 (cellubrevin)0.323
C1QCcomplement component 1, q subcomponent, C chain0.317
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.316
SPINT1serine peptidase inhibitor, Kunitz type 10.283
LATlinker for activation of T cells0.279
CYBAcytochrome b-245, alpha polypeptide0.270
PCYT2phosphate cytidylyltransferase 2, ethanolamine0.269
POU5F1POU class 5 homeobox 10.269
SNAP25synaptosomal-associated protein, 25kDa0.247
F13A1coagulation factor XIII, A1 polypeptide0.245
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.231
PGFplacental growth factor0.230
A2Malpha-2-macroglobulin0.225
SHC2SHC (Src homology 2 domain containing) transforming protein 20.224
GRB7growth factor receptor-bound protein 70.211
FYNFYN oncogene related to SRC, FGR, YES0.207
ALBalbumin0.203
CTNND1catenin (cadherin-associated protein), delta 10.200
CD93CD93 molecule0.196
MS4A6Amembrane-spanning 4-domains, subfamily A, member 6A0.194
PTPRBprotein tyrosine phosphatase, receptor type, B0.178
PTPN6protein tyrosine phosphatase, non-receptor type 60.176
KEAP1kelch-like ECH-associated protein 10.175
PLGplasminogen0.174
FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32)0.172
APOC1apolipoprotein C-I0.159
BLNKB-cell linker0.158
SERPINC1serpin peptidase inhibitor, clade C (antithrombin), member 10.154
TICAM2toll-like receptor adaptor molecule 20.148
BTKBruton agammaglobulinemia tyrosine kinase0.146
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.144
S100A10S100 calcium binding protein A100.142
SIGLEC1sialic acid binding Ig-like lectin 1, sialoadhesin0.136
ANXA1annexin A10.132
SPRR2Asmall proline-rich protein 2A0.130
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.129
HPhaptoglobin0.128
KNG1kininogen 10.124
PLATplasminogen activator, tissue0.122
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.115
PAG1phosphoprotein associated with glycosphingolipid microdomains 10.113
CD163CD163 molecule0.112
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.111
LCKlymphocyte-specific protein tyrosine kinase0.110
FGBfibrinogen beta chain0.101
F2Rcoagulation factor II (thrombin) receptor0.097
PDGFCplatelet derived growth factor C0.095
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.093
APOA2apolipoprotein A-II0.091
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.088
SHC1SHC (Src homology 2 domain containing) transforming protein 10.086
PKLRpyruvate kinase, liver and RBC0.084
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.084
C8Acomplement component 8, alpha polypeptide0.080
CDH5cadherin 5, type 2 (vascular endothelium)0.079
F3coagulation factor III (thromboplastin, tissue factor)0.077
MASP2mannan-binding lectin serine peptidase 20.076
ARandrogen receptor0.076
TRIM9tripartite motif containing 90.074
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.071
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.071
PECAM1platelet/endothelial cell adhesion molecule0.070
VWFvon Willebrand factor0.070
COL4A1collagen, type IV, alpha 10.069
SLASrc-like-adaptor0.067
FASLGFas ligand (TNF superfamily, member 6)0.066
NCF4neutrophil cytosolic factor 4, 40kDa0.064
ERGv-ets erythroblastosis virus E26 oncogene homolog (avian)0.064
PDGFAplatelet-derived growth factor alpha polypeptide0.062
PLAURplasminogen activator, urokinase receptor0.061
CAV2caveolin 20.060
ZNF775zinc finger protein 7750.059
MS4A7membrane-spanning 4-domains, subfamily A, member 70.058
NR2F2nuclear receptor subfamily 2, group F, member 20.057
FGAfibrinogen alpha chain0.055
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
nkx2.3NK2 transcription factor related 30.119
foxa1forkhead box A10.113
ambplalpha-1-microglobulin/bikunin precursor, like0.087
fetubfetuin B0.070
c9complement component 90.066
apoc2apolipoprotein C-II0.063
pdgfaaplatelet-derived growth factor alpha a0.062
itih2inter-alpha (globulin) inhibitor H20.059
zgc:193613zgc:1936130.054
tfatransferrin-a0.053
fggfibrinogen, gamma polypeptide0.053
foxa3forkhead box A30.048
plgplasminogen0.045
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.045
apomapolipoprotein M0.044
uoxurate oxidase0.042
vtnbvitronectin b0.040
fgafibrinogen alpha chain0.039
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.036
pklrpyruvate kinase, liver and RBC0.033
serpinc1serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 10.032
gipgastric inhibitory polypeptide0.032
serpinf2serine (or cysteine) peptidase inhibitor, clade F, member 20.032
hnf4ahepatocyte nuclear factor 4, alpha0.030
col11a1acollagen, type XI, alpha 1a0.026
alas2aminolevulinate, delta-, synthetase 20.025
sulf1sulfatase 10.025
igfbp2ainsulin-like growth factor binding protein 2a0.024
serpind1serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 10.023
serpina1lserine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like0.021
f5coagulation factor V0.021
cfhl4complement factor H like 40.021
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.021
fbp1bfructose-1,6-bisphosphatase 1b0.020
dhrs9dehydrogenase/reductase (SDR family) member 90.020
cpa5carboxypeptidase A50.020
slc20a1asolute carrier family 20, member 1a0.019
zgc:161979zgc:1619790.019
cyp24a1cytochrome P450, family 24, subfamily A, polypeptide 10.019
hphaptoglobin0.019
a1cfapobec1 complementation factor0.019
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.019
LOC100003514protein kinase C alpha type-like0.019
si:dkeyp-94b4.2si:dkeyp-94b4.20.019
cd63Cd63 antigen0.018
tagln2transgelin 20.018
aldh8a1aldehyde dehydrogenase 8 family, member A10.018
si:dkeyp-50f5.1si:dkeyp-50f5.10.018
blvrbbiliverdin reductase B (flavin reductase (NADPH))0.018
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.018
col5a3bcollagen type V alpha-3b0.018
cdh4cadherin 4, retinal0.017
rhdRh blood group, D antigen0.017
cpceruloplasmin0.017
pdgfrb2platelet derived growth factor receptor beta 20.017
npntnephronectin0.017
zgc:63721zgc:637210.016
masp2mannan-binding lectin serine peptidase 20.016
cyp2ad2cytochrome P450, family 2, subfamily AD, polypeptide 20.016
mst1macrophage stimulating 1 (hepatocyte growth factor-like)0.016
anxa1aannexin A1a0.016
sptbspectrin, beta, erythrocytic0.016
ogt.1O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) 10.016
junjun proto-oncogene0.015
shbgsex hormone binding globulin0.015
nr1h5nuclear receptor subfamily 1, group H, member 50.015
ovol1ovo-like 1 (Drosophila)0.015
dusp6dual specificity phosphatase 60.015
rock2brho-associated, coiled-coil containing protein kinase 2b0.015
si:dkey-8l13.4si:dkey-8l13.40.015
zgc:56326zgc:563260.015
fn1bfibronectin 1b0.014
ahcyS-adenosylhomocysteine hydrolase0.014
ces2carboxylesterase 2 (intestine, liver)0.014
cldn15laclaudin 15-like a0.014
anxa2aannexin A2a0.014
il6rinterleukin 6 receptor0.014
kng1kininogen 10.014
smoc2secreted modular calcium binding protein 20.014
si:dkey-76b14.4si:dkey-76b14.40.014
agxtaalanine-glyoxylate aminotransferase a0.014
dlx5adistal-less homeobox gene 5a0.014
bfbcomplement component bfb0.014
bmp5bone morphogenetic protein 50.014
eif2c3eukaryotic translation initiation factor 2C, 30.014
mybl1v-myb myeloblastosis viral oncogene homolog (avian)-like 10.013
klfdKruppel-like factor d0.013
nt5c2l15'-nucleotidase, cytosolic II, like 10.013
optcopticin0.013
fth1aferritin, heavy polypeptide 1a0.013
zgc:66433zgc:664330.013
rhoubras homolog gene family, member Ub0.013
ftcdformiminotransferase cyclodeaminase0.013
sc:d0144sc:d01440.013
tp63tumor protein p630.013
slc10a4solute carrier family 10 (sodium/bile acid cotransporter family), member 40.013
tspan7btetraspanin 7b0.013
cyyr1cysteine and tyrosine-rich protein 10.013
si:dkey-12o15.1si:dkey-12o15.10.013
c8acomplement component 8, alpha polypeptide0.013
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Dysfdysferlin0.882
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.799
Ldb3LIM domain binding 30.783
Prkceprotein kinase C, epsilon0.713
Plgplasminogen0.682
Lyz2lysozyme 20.672
Vhlvon Hippel-Lindau tumor suppressor0.613
Ptgs2prostaglandin-endoperoxide synthase 20.488
Ppargperoxisome proliferator activated receptor gamma0.467
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.447
Ceacam2carcinoembryonic antigen-related cell adhesion molecule 20.438
BlnkB-cell linker0.431
Ptprcprotein tyrosine phosphatase, receptor type, C0.425
Procprotein C0.396
F2coagulation factor II0.371
Zap70zeta-chain (TCR) associated protein kinase0.368
Smad1MAD homolog 1 (Drosophila)0.357
Itih4inter alpha-trypsin inhibitor, heavy chain 40.347
SrcRous sarcoma oncogene0.335
1300017J02RikRIKEN cDNA 1300017J02 gene0.330
FasFas (TNF receptor superfamily member 6)0.261
Alox5aparachidonate 5-lipoxygenase activating protein0.261
FcrlaFc receptor-like A0.253
Cficomplement component factor i0.237
Mmp9matrix metallopeptidase 90.226
Trim10tripartite motif-containing 100.224
Asgr2asialoglycoprotein receptor 20.221
Sykbspleen tyrosine kinase0.219
Cpn1carboxypeptidase N, polypeptide 10.212
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.208
Bcl2B-cell leukemia/lymphoma 20.206
Apobapolipoprotein B0.205
S1pr2sphingosine-1-phosphate receptor 20.198
F11coagulation factor XI0.198
Halhistidine ammonia lyase0.197
Saa4serum amyloid A 40.195
Plauplasminogen activator, urokinase0.189
Fggfibrinogen gamma chain0.184
Serpinc1serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 10.180
Itgb3integrin beta 30.180
Hgfachepatocyte growth factor activator0.172
Itih1inter-alpha trypsin inhibitor, heavy chain 10.168
Pklrpyruvate kinase liver and red blood cell0.165
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.164
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.161
Slc27a5solute carrier family 27 (fatty acid transporter), member 50.160
Selpselectin, platelet0.159
Snap23synaptosomal-associated protein 230.154
Seleselectin, endothelial cell0.153
Itgb1integrin beta 1 (fibronectin receptor beta)0.152
Pou2af1POU domain, class 2, associating factor 10.151
Gcgroup specific component0.149
C9complement component 90.146
Il1ainterleukin 1 alpha0.133
Nfe2l2nuclear factor, erythroid derived 2, like 20.131
Apoa1apolipoprotein A-I0.129
Hgdhomogentisate 1, 2-dioxygenase0.127
FynFyn proto-oncogene0.127
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.125
Cav1caveolin 1, caveolae protein0.124
Ptk2PTK2 protein tyrosine kinase 20.123
Eporerythropoietin receptor0.122
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.119
Apoa5apolipoprotein A-V0.116
Afmafamin0.116
Pcdh12protocadherin 120.116
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.115
Lipclipase, hepatic0.115
Ush1cUsher syndrome 1C homolog (human)0.115
Cd19CD19 antigen0.115
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.114
Lgals3lectin, galactose binding, soluble 30.114
Tnfrsf11btumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)0.113
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.113
Ccr2chemokine (C-C motif) receptor 20.108
P2rx1purinergic receptor P2X, ligand-gated ion channel, 10.108
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.107
Prg3proteoglycan 30.107
F7coagulation factor VII0.107
Lcklymphocyte protein tyrosine kinase0.107
Tlr2toll-like receptor 20.105
C3complement component 30.099
Mt2metallothionein 20.099
Hbb-b1hemoglobin, beta adult major chain0.097
Plaurplasminogen activator, urokinase receptor0.096
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.096
Prkccprotein kinase C, gamma0.095
Pzppregnancy zone protein0.092
Insrinsulin receptor0.090
Apofapolipoprotein F0.089
Trfr2transferrin receptor 20.087
F10coagulation factor X0.086
Ambpalpha 1 microglobulin/bikunin0.086
Serpind1serine (or cysteine) peptidase inhibitor, clade D, member 10.086
Fcgr1Fc receptor, IgG, high affinity I0.082
Epas1endothelial PAS domain protein 10.079
C5ar1complement component 5a receptor 10.079
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.078
Gpr97G protein-coupled receptor 970.077
Nf1neurofibromatosis 10.077
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Anxa5annexin A50.707
Anxa1annexin A10.567
Pzppregnancy-zone protein0.487
Serpina1serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10.363
Apohapolipoprotein H (beta-2-glycoprotein I)0.355
Ahsgalpha-2-HS-glycoprotein0.266
Ifitm3interferon induced transmembrane protein 30.241
S100a6S100 calcium binding protein A60.232
Cma1chymase 1, mast cell0.204
Gcgroup specific component0.179
Itgb1integrin, beta 10.166
Ctsl1cathepsin L10.159
Fabp1fatty acid binding protein 1, liver0.150
AhnakAHNAK nucleoprotein0.134
Cpb2carboxypeptidase B2 (plasma)0.131
Anxa2annexin A20.086
Cd151CD151 molecule (Raph blood group)0.085
Ccl2chemokine (C-C motif) ligand 20.079
Serpina6serine (or cysteine) peptidase inhibitor, clade A, member 60.078
Albalbumin0.072
Vimvimentin0.070
Ctsbcathepsin B0.054
Ambpalpha-1-microglobulin/bikunin precursor0.051
Slc10a1solute carrier family 10 (sodium/bile acid cotransporter family), member 10.051
Rup2urinary protein 20.047
S100a10S100 calcium binding protein A100.043
Spp2secreted phosphoprotein 20.042
MdficMyoD family inhibitor domain containing0.041
Serpina10serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 100.041
Mbl2mannose-binding lectin (protein C) 20.039
Cfpcomplement factor properdin0.037
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.037
C1scomplement component 1, s subcomponent0.035
Lgals3lectin, galactoside-binding, soluble, 30.035
Itih4inter alpha-trypsin inhibitor, heavy chain 40.034
Ctrcchymotrypsin C (caldecrin)0.034
Lamp2lysosomal-associated membrane protein 20.034
Procprotein C0.033
Capn2calpain 20.033
Cd9CD9 molecule0.033
Tm4sf1transmembrane 4 L six family member 10.031
Apoa2apolipoprotein A-II0.031
Myadmmyeloid-associated differentiation marker0.030
LOC293989cytochrome P450-like0.029
Serpinf2serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 20.027
Serpinb6aserine (or cysteine) peptidase inhibitor, clade B, member 6a0.027
Azgp1alpha-2-glycoprotein 1, zinc-binding0.026
Anxa4annexin A40.023
S100a4S100 calcium-binding protein A40.022
Vamp3vesicle-associated membrane protein 30.022
Haao3-hydroxyanthranilate 3,4-dioxygenase0.021
Mbl1mannose-binding lectin (protein A) 10.021
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.020
Ttc36tetratricopeptide repeat domain 360.019
Cpn1carboxypeptidase N, polypeptide 10.019
Ramp1receptor (G protein-coupled) activity modifying protein 10.019
Tmem59transmembrane protein 590.018
Qprtquinolinate phosphoribosyltransferase0.018
Pgcpplasma glutamate carboxypeptidase0.018
Lpllipoprotein lipase0.018
Smgbneonatal submandibular gland protein B0.018
C1rcomplement component 1, r subcomponent0.017
Cyp2b3cytochrome P450, family 2, subfamily b, polypeptide 30.016
Pmp22peripheral myelin protein 220.015
Itm2bintegral membrane protein 2B0.015
Cyp2d2cytochrome P450, family 2, subfamily d, polypeptide 20.015
S100a11S100 calcium binding protein A11 (calizzarin)0.015
Tnfrsf14tumor necrosis factor receptor superfamily, member 14 (herpesvirus entry mediator)0.015
Plauplasminogen activator, urokinase0.015
Clec4fC-type lectin domain family 4, member f0.015
Pnliprp2pancreatic lipase-related protein 20.014
Ghrgrowth hormone receptor0.013
Krt5keratin 50.013
Apcsamyloid P component, serum0.013
Gsngelsolin0.013
Syt8synaptotagmin VIII0.013
Cficomplement factor I0.013
F12coagulation factor XII (Hageman factor)0.013
Villvillin-like0.012
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.012
Rarres2retinoic acid receptor responder (tazarotene induced) 20.012
Fggfibrinogen gamma chain0.012
Agtr1aangiotensin II receptor, type 1a0.011
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.011
Ttrtransthyretin0.011
Gja1gap junction protein, alpha 10.011
Tmbim1transmembrane BAX inhibitor motif containing 10.011
Cst8cystatin 8 (cystatin-related epididymal specific)0.011
Adam7ADAM metallopeptidase domain 70.011
Rnase4ribonuclease, RNase A family 40.011
Ptger3prostaglandin E receptor 3 (subtype EP3)0.010
Pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.010
C8bcomplement component 8, beta polypeptide0.010
Zg16zymogen granule protein 160.010
Slc2a3solute carrier family 2 (facilitated glucose transporter), member 30.010
Serpinc1serpin peptidase inhibitor, clade C (antithrombin), member 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism