The network for 'regulation of interleukin 2 secretion' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of interleukin 2 secretion

Any process that modulates the frequency, rate or extent of interleukin-2 secretion.

NameDescriptionProbabilityFunc Analog Organism
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.970
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.936
UBE2D4ubiquitin-conjugating enzyme E2D 4 (putative)0.835
TRIM39tripartite motif containing 390.831
BCAR1breast cancer anti-estrogen resistance 10.820
RAPGEF1Rap guanine nucleotide exchange factor (GEF) 10.817
TRIM5tripartite motif containing 50.804
MED15mediator complex subunit 150.781
EGFRepidermal growth factor receptor0.702
RIN1Ras and Rab interactor 10.591
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.545
SPRR2Asmall proline-rich protein 2A0.446
TRIM21tripartite motif containing 210.432
ZNF263zinc finger protein 2630.421
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.335
RNF126ring finger protein 1260.320
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.307
RBCK1RanBP-type and C3HC4-type zinc finger containing 10.263
TRIM8tripartite motif containing 80.256
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.237
SHC1SHC (Src homology 2 domain containing) transforming protein 10.216
SP100SP100 nuclear antigen0.194
ZNRF1zinc and ring finger 10.169
ABI2abl-interactor 20.166
MUC1mucin 1, cell surface associated0.163
TRIM17tripartite motif containing 170.154
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.154
XIAPX-linked inhibitor of apoptosis0.138
TRIM32tripartite motif containing 320.132
TRIM43tripartite motif containing 430.132
MSH5mutS homolog 5 (E. coli)0.129
TRIM26tripartite motif containing 260.128
TRIM34tripartite motif containing 340.125
DAXXdeath-domain associated protein0.124
SOS1son of sevenless homolog 1 (Drosophila)0.116
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.112
RNF5ring finger protein 50.110
UBE2Uubiquitin-conjugating enzyme E2U (putative)0.092
MSH4mutS homolog 4 (E. coli)0.092
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.088
TRIM41tripartite motif containing 410.072
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.068
SP110SP110 nuclear body protein0.068
CTSOcathepsin O0.068
MCOLN1mucolipin 10.067
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.064
PMLpromyelocytic leukemia0.055
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.054
ZNF473zinc finger protein 4730.052
PRKCAprotein kinase C, alpha0.051
SREBF1sterol regulatory element binding transcription factor 10.048
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.046
USP4ubiquitin specific peptidase 4 (proto-oncogene)0.046
TRIM35tripartite motif containing 350.042
MAVSmitochondrial antiviral signaling protein0.042
RNF11ring finger protein 110.041
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.040
PLSCR1phospholipid scramblase 10.040
ARIH2ariadne homolog 2 (Drosophila)0.040
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.039
UBE2Zubiquitin-conjugating enzyme E2Z0.038
TRIM52tripartite motif containing 520.034
HIPK2homeodomain interacting protein kinase 20.034
SHANK3SH3 and multiple ankyrin repeat domains 30.034
SYKspleen tyrosine kinase0.033
IRF9interferon regulatory factor 90.031
DTX3Ldeltex 3-like (Drosophila)0.030
RNF130ring finger protein 1300.030
SHBSrc homology 2 domain containing adaptor protein B0.030
TRANK1tetratricopeptide repeat and ankyrin repeat containing 10.029
PIK3C2Bphosphoinositide-3-kinase, class 2, beta polypeptide0.029
RNF4ring finger protein 40.028
TRIM6-TRIM34TRIM6-TRIM34 readthrough0.028
FASFas (TNF receptor superfamily, member 6)0.028
PLCG1phospholipase C, gamma 10.027
ERBB4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.026
MR1major histocompatibility complex, class I-related0.025
SAMD9sterile alpha motif domain containing 90.025
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.025
IRF2interferon regulatory factor 20.025
MUL1mitochondrial E3 ubiquitin protein ligase 10.024
FADDFas (TNFRSF6)-associated via death domain0.023
TRIM25tripartite motif containing 250.023
MEX3Bmex-3 homolog B (C. elegans)0.023
GIMAP2GTPase, IMAP family member 20.023
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.022
STAT5Asignal transducer and activator of transcription 5A0.022
RAD52RAD52 homolog (S. cerevisiae)0.022
CHFRcheckpoint with forkhead and ring finger domains0.022
RASSF1Ras association (RalGDS/AF-6) domain family member 10.021
TRIM4tripartite motif containing 40.021
ADAM19ADAM metallopeptidase domain 190.020
TLN2talin 20.020
SORBS1sorbin and SH3 domain containing 10.020
PHF11PHD finger protein 110.020
ELK1ELK1, member of ETS oncogene family0.019
MLLT6myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 60.019
DNMT3BDNA (cytosine-5-)-methyltransferase 3 beta0.019
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.019
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ric8resistance to inhibitors of cholinesterase 8 homolog (C. elegans)0.999
Cd80CD80 antigen0.997
Dok1docking protein 10.740
Abl2v-abl Abelson murine leukemia viral oncogene homolog 2 (arg, Abelson-related gene)0.540
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.411
En1engrailed 10.406
Abl1c-abl oncogene 1, non-receptor tyrosine kinase0.382
Inpp5dinositol polyphosphate-5-phosphatase D0.101
Tbx21T-box 210.099
Itgb1integrin beta 1 (fibronectin receptor beta)0.089
Cd5CD5 antigen0.083
Slamf1signaling lymphocytic activation molecule family member 10.081
Foxp1forkhead box P10.064
Cxcl9chemokine (C-X-C motif) ligand 90.061
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.055
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.051
Rc3h1RING CCCH (C3H) domains 10.050
Dok2docking protein 20.048
Plp1proteolipid protein (myelin) 10.043
Batf2basic leucine zipper transcription factor, ATF-like 20.035
Zfp362zinc finger protein 3620.029
Batf3basic leucine zipper transcription factor, ATF-like 30.024
Llgl1lethal giant larvae homolog 1 (Drosophila)0.021
Slamf8SLAM family member 80.020
Parp14poly (ADP-ribose) polymerase family, member 140.018
Zbp1Z-DNA binding protein 10.017
Cd274CD274 antigen0.016
Ccr7chemokine (C-C motif) receptor 70.015
Sh3bp1SH3-domain binding protein 10.013
Nck1non-catalytic region of tyrosine kinase adaptor protein 10.012
Lag3lymphocyte-activation gene 30.012
Oas32'-5' oligoadenylate synthetase 30.012
Ubdubiquitin D0.011
Naip6NLR family, apoptosis inhibitory protein 60.011
Ubap2ubiquitin-associated protein 20.011
Trim28tripartite motif-containing 280.011
Cd8aCD8 antigen, alpha chain0.011
Atxn7l3ataxin 7-like 30.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism