The network for 'cellular response to thyroid hormone stimulus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to thyroid hormone stimulus

A change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a thyroid hormone stimulus.

NameDescriptionProbabilityFunc Analog Organism
TAL1T-cell acute lymphocytic leukemia 10.999
ESRRGestrogen-related receptor gamma0.610
PPARGperoxisome proliferator-activated receptor gamma0.597
HEXBhexosaminidase B (beta polypeptide)0.414
RGS2regulator of G-protein signaling 2, 24kDa0.302
LDB1LIM domain binding 10.284
NPC2Niemann-Pick disease, type C20.262
COL3A1collagen, type III, alpha 10.251
COL1A1collagen, type I, alpha 10.245
HNF4Ahepatocyte nuclear factor 4, alpha0.232
CDK8cyclin-dependent kinase 80.226
CSTAcystatin A (stefin A)0.184
PSAPprosaposin0.155
SEC24DSEC24 family, member D (S. cerevisiae)0.115
GATA2GATA binding protein 20.088
KITLGKIT ligand0.082
MAPRE2microtubule-associated protein, RP/EB family, member 20.076
CD63CD63 molecule0.068
INCENPinner centromere protein antigens 135/155kDa0.063
GPNMBglycoprotein (transmembrane) nmb0.063
GATA4GATA binding protein 40.062
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.057
MED6mediator complex subunit 60.057
MED14mediator complex subunit 140.050
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.049
LDB2LIM domain binding 20.038
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.037
TPP1tripeptidyl peptidase I0.036
CTSL1cathepsin L10.036
NR0B2nuclear receptor subfamily 0, group B, member 20.036
MED29mediator complex subunit 290.036
TBX5T-box 50.033
LY96lymphocyte antigen 960.033
LOXlysyl oxidase0.032
RXRAretinoid X receptor, alpha0.032
GATA1GATA binding protein 1 (globin transcription factor 1)0.032
GRNgranulin0.030
MED10mediator complex subunit 100.030
CSTBcystatin B (stefin B)0.029
AMBPalpha-1-microglobulin/bikunin precursor0.029
S100A4S100 calcium binding protein A40.029
TGFBItransforming growth factor, beta-induced, 68kDa0.026
ZFPM1zinc finger protein, multitype 10.026
IFI30interferon, gamma-inducible protein 300.024
PROX1prospero homeobox 10.024
MDM2Mdm2 p53 binding protein homolog (mouse)0.023
HLA-DMBmajor histocompatibility complex, class II, DM beta0.023
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.022
RUNX1runt-related transcription factor 10.020
TMSB4Xthymosin beta 4, X-linked0.019
TGS1trimethylguanosine synthase 10.018
CDK19cyclin-dependent kinase 190.018
THRAP3thyroid hormone receptor associated protein 30.018
FOXO1forkhead box O10.017
CST3cystatin C0.017
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.017
MXRA5matrix-remodelling associated 50.016
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.016
KLF13Kruppel-like factor 130.015
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.015
TCF21transcription factor 210.014
NR5A1nuclear receptor subfamily 5, group A, member 10.014
TIMP2TIMP metallopeptidase inhibitor 20.014
GNSglucosamine (N-acetyl)-6-sulfatase0.014
LYL1lymphoblastic leukemia derived sequence 10.014
CTSBcathepsin B0.014
HAND2heart and neural crest derivatives expressed 20.014
LMO2LIM domain only 2 (rhombotin-like 1)0.014
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)0.014
COL5A2collagen, type V, alpha 20.013
GADD45Agrowth arrest and DNA-damage-inducible, alpha0.013
LGMNlegumain0.013
NCOA1nuclear receptor coactivator 10.013
S100A10S100 calcium binding protein A100.013
POSTNperiostin, osteoblast specific factor0.013
FAPfibroblast activation protein, alpha0.013
TNFSF11tumor necrosis factor (ligand) superfamily, member 110.012
ZFYVE9zinc finger, FYVE domain containing 90.012
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.012
SPRY2sprouty homolog 2 (Drosophila)0.012
GRB7growth factor receptor-bound protein 70.012
SQRDLsulfide quinone reductase-like (yeast)0.012
KIF3Bkinesin family member 3B0.012
MED13mediator complex subunit 130.012
CDH11cadherin 11, type 2, OB-cadherin (osteoblast)0.011
DCNdecorin0.011
B2Mbeta-2-microglobulin0.011
GAB2GRB2-associated binding protein 20.011
ESR2estrogen receptor 2 (ER beta)0.011
ZBTB16zinc finger and BTB domain containing 160.011
TIMP1TIMP metallopeptidase inhibitor 10.011
DEPDC1DEP domain containing 10.011
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.011
MAFBv-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)0.010
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.010
ANXA2annexin A20.010
CREG1cellular repressor of E1A-stimulated genes 10.010
IL10RBinterleukin 10 receptor, beta0.010
MPEG1macrophage expressed 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Vegfavascular endothelial growth factor A0.976
TyrobpTYRO protein tyrosine kinase binding protein0.842
Nos3nitric oxide synthase 3, endothelial cell0.735
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.670
Col1a1collagen, type I, alpha 10.501
Foxc2forkhead box C20.452
Lgmnlegumain0.416
Tal1T-cell acute lymphocytic leukemia 10.400
Tie1tyrosine kinase with immunoglobulin-like and EGF-like domains 10.319
Cdh5cadherin 50.310
Ptprbprotein tyrosine phosphatase, receptor type, B0.289
Ctsdcathepsin D0.281
Tgfbr2transforming growth factor, beta receptor II0.259
Ly86lymphocyte antigen 860.227
C1qacomplement component 1, q subcomponent, alpha polypeptide0.208
C1qccomplement component 1, q subcomponent, C chain0.207
Zeb1zinc finger E-box binding homeobox 10.196
Tgfb2transforming growth factor, beta 20.193
Tekendothelial-specific receptor tyrosine kinase0.176
Lamp1lysosomal-associated membrane protein 10.168
Kitlkit ligand0.165
Fgfr2fibroblast growth factor receptor 20.164
C1qbcomplement component 1, q subcomponent, beta polypeptide0.160
Foxc1forkhead box C10.158
Agtr2angiotensin II receptor, type 20.150
Gli3GLI-Kruppel family member GLI30.142
Kdrkinase insert domain protein receptor0.131
Ptpn11protein tyrosine phosphatase, non-receptor type 110.130
Esamendothelial cell-specific adhesion molecule0.126
CblCasitas B-lineage lymphoma0.125
Eporerythropoietin receptor0.113
Grngranulin0.113
Bicc1bicaudal C homolog 1 (Drosophila)0.106
Slc9a3r2solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 20.104
Gata6GATA binding protein 60.104
Gja1gap junction protein, alpha 10.098
Ctszcathepsin Z0.095
Lamp2lysosomal-associated membrane protein 20.090
Mitfmicrophthalmia-associated transcription factor0.087
Bgnbiglycan0.087
Meox2mesenchyme homeobox 20.087
Flt1FMS-like tyrosine kinase 10.086
Tmem204transmembrane protein 2040.085
Engendoglin0.082
Vegfcvascular endothelial growth factor C0.076
Psapprosaposin0.074
Plvapplasmalemma vesicle associated protein0.073
Lyz1lysozyme 10.073
B2mbeta-2 microglobulin0.072
Esr1estrogen receptor 1 (alpha)0.069
Podxlpodocalyxin-like0.069
Ldlrlow density lipoprotein receptor0.068
Shesrc homology 2 domain-containing transforming protein E0.067
Cxcl12chemokine (C-X-C motif) ligand 120.066
Tmem176atransmembrane protein 176A0.066
Ctslcathepsin L0.064
Sox18SRY-box containing gene 180.061
Ppargc1bperoxisome proliferative activated receptor, gamma, coactivator 1 beta0.061
Ednrbendothelin receptor type B0.059
Aplnrapelin receptor0.055
Hexahexosaminidase A0.055
Fzd4frizzled homolog 4 (Drosophila)0.055
Apoeapolipoprotein E0.055
Bmp2bone morphogenetic protein 20.054
Gnsglucosamine (N-acetyl)-6-sulfatase0.053
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.053
Arap3ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 30.052
Ednraendothelin receptor type A0.049
Nid1nidogen 10.049
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.048
Emcnendomucin0.047
Ctsccathepsin C0.047
Cd68CD68 antigen0.047
Sat1spermidine/spermine N1-acetyl transferase 10.047
Ppargperoxisome proliferator activated receptor gamma0.045
Lmo2LIM domain only 20.044
VwfVon Willebrand factor homolog0.044
Ldb2LIM domain binding 20.042
Notch2Notch gene homolog 2 (Drosophila)0.041
Cav1caveolin 1, caveolae protein0.041
Fbln1fibulin 10.041
Gata4GATA binding protein 40.040
Cd53CD53 antigen0.040
Lipalysosomal acid lipase A0.040
Hexbhexosaminidase B0.039
Fgfr1fibroblast growth factor receptor 10.038
Robo4roundabout homolog 4 (Drosophila)0.038
Pdgfbplatelet derived growth factor, B polypeptide0.038
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.038
Itgb1integrin beta 1 (fibronectin receptor beta)0.037
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.037
0610031J06RikRIKEN cDNA 0610031J06 gene0.037
Gfi1bgrowth factor independent 1B0.036
Per1period homolog 1 (Drosophila)0.036
Mpeg1macrophage expressed gene 10.035
Leprleptin receptor0.035
Ltbp3latent transforming growth factor beta binding protein 30.035
Mmp2matrix metallopeptidase 20.034
Pecam1platelet/endothelial cell adhesion molecule 10.034
Mrc1mannose receptor, C type 10.034
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Col1a1collagen, type I, alpha 10.955
Col1a2collagen, type I, alpha 20.857
Col3a1collagen, type III, alpha 10.703
Col5a2collagen, type V, alpha 20.306
Col5a1collagen, type V, alpha 10.249
Postnperiostin, osteoblast specific factor0.171
Sparcsecreted protein, acidic, cysteine-rich (osteonectin)0.066
Loxl1lysyl oxidase-like 10.051
Fbn1fibrillin 10.050
Fstl1follistatin-like 10.041
Col4a1collagen, type IV, alpha 10.028
Lumlumican0.025
Col14a1collagen, type XIV, alpha 10.024
Fn1fibronectin 10.023
Col12a1collagen, type XII, alpha 10.021
Fuca1fucosidase, alpha-L- 1, tissue0.019
Ccdc80coiled-coil domain containing 800.019
Elnelastin0.015
Ognosteoglycin0.012
Pgcpplasma glutamate carboxypeptidase0.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism