The network for 'myeloid dendritic cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

myeloid dendritic cell differentiation

The process in which a monocyte acquires the specialized features of a dendritic cell, an immunocompetent cell of the lymphoid and hemopoietic systems and skin.

NameDescriptionProbabilityFunc Analog Organism
TGFB1transforming growth factor, beta 10.967
NOTCH1notch 10.955
CTLA4cytotoxic T-lymphocyte-associated protein 40.806
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.770
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.648
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.589
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.576
PSEN2presenilin 2 (Alzheimer disease 4)0.480
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.421
TGFB3transforming growth factor, beta 30.398
JAG1jagged 10.350
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.263
CD80CD80 molecule0.246
TGFBR1transforming growth factor, beta receptor 10.199
SPENspen homolog, transcriptional regulator (Drosophila)0.177
PSMD2proteasome (prosome, macropain) 26S subunit, non-ATPase, 20.156
ATXN1Lataxin 1-like0.156
FSTL1follistatin-like 10.125
MAML1mastermind-like 1 (Drosophila)0.123
FLNBfilamin B, beta0.104
DAZAP2DAZ associated protein 20.103
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.090
ICAM1intercellular adhesion molecule 10.071
PEX5peroxisomal biogenesis factor 50.068
APPamyloid beta (A4) precursor protein0.065
CD40CD40 molecule, TNF receptor superfamily member 50.058
ATXN3ataxin 30.049
NRP1neuropilin 10.045
CSF2RAcolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)0.042
IRAK2interleukin-1 receptor-associated kinase 20.042
TRIM32tripartite motif containing 320.041
UBE2Zubiquitin-conjugating enzyme E2Z0.039
TRAF3TNF receptor-associated factor 30.039
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.039
TRAF1TNF receptor-associated factor 10.035
NUMBLnumb homolog (Drosophila)-like0.034
PEX14peroxisomal biogenesis factor 140.031
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.029
NCOR2nuclear receptor corepressor 20.028
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.028
BATFbasic leucine zipper transcription factor, ATF-like0.028
TNFAIP2tumor necrosis factor, alpha-induced protein 20.028
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.027
SQSTM1sequestosome 10.026
TGFBR3transforming growth factor, beta receptor III0.025
GFI1growth factor independent 1 transcription repressor0.025
DLL1delta-like 1 (Drosophila)0.024
CEBPACCAAT/enhancer binding protein (C/EBP), alpha0.024
IL2RAinterleukin 2 receptor, alpha0.023
TNFRSF9tumor necrosis factor receptor superfamily, member 90.023
TRAF3IP2TRAF3 interacting protein 20.022
ETV7ets variant 70.022
SOCS1suppressor of cytokine signaling 10.021
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.021
CD83CD83 molecule0.020
CIR1corepressor interacting with RBPJ, 10.020
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.020
APBA1amyloid beta (A4) precursor protein-binding, family A, member 10.019
CD28CD28 molecule0.019
NOTCH3notch 30.019
BAG3BCL2-associated athanogene 30.018
SMAD1SMAD family member 10.018
EBI3Epstein-Barr virus induced 30.018
CXCL13chemokine (C-X-C motif) ligand 130.018
PELI3pellino homolog 3 (Drosophila)0.018
TICAM1toll-like receptor adaptor molecule 10.017
NOTCH2notch 20.017
CXCL11chemokine (C-X-C motif) ligand 110.017
SLAMF7SLAM family member 70.017
SLAMF1signaling lymphocytic activation molecule family member 10.016
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.016
FCER2Fc fragment of IgE, low affinity II, receptor for (CD23)0.016
NUB1negative regulator of ubiquitin-like proteins 10.016
IQGAP1IQ motif containing GTPase activating protein 10.016
CCL22chemokine (C-C motif) ligand 220.015
SMURF2SMAD specific E3 ubiquitin protein ligase 20.015
DIP2ADIP2 disco-interacting protein 2 homolog A (Drosophila)0.015
BCL6B-cell CLL/lymphoma 60.015
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.014
IL21Rinterleukin 21 receptor0.014
AIM2absent in melanoma 20.014
APOBRapolipoprotein B receptor0.014
JUNBjun B proto-oncogene0.014
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.014
PDGFCplatelet derived growth factor C0.013
BTRCbeta-transducin repeat containing0.013
TNFSF8tumor necrosis factor (ligand) superfamily, member 80.013
NEK6NIMA (never in mitosis gene a)-related kinase 60.013
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.013
SYVN1synovial apoptosis inhibitor 1, synoviolin0.013
PILRApaired immunoglobin-like type 2 receptor alpha0.013
DNAJB2DnaJ (Hsp40) homolog, subfamily B, member 20.012
FOSL1FOS-like antigen 10.012
TACC1transforming, acidic coiled-coil containing protein 10.012
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.012
ZNF746zinc finger protein 7460.012
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.012
SESN2sestrin 20.011
ZNF675zinc finger protein 6750.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1001.000
Ighimmunoglobulin heavy chain complex0.998
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.994
Notch1Notch gene homolog 1 (Drosophila)0.990
Psen1presenilin 10.982
Ctnnb1catenin (cadherin associated protein), beta 10.952
Cd19CD19 antigen0.928
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.902
Cd40CD40 antigen0.902
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.875
Ifnginterferon gamma0.868
Socs1suppressor of cytokine signaling 10.818
Notch2Notch gene homolog 2 (Drosophila)0.816
Tnfaip3tumor necrosis factor, alpha-induced protein 30.809
Irf4interferon regulatory factor 40.804
Irf5interferon regulatory factor 50.803
Csf1colony stimulating factor 1 (macrophage)0.797
Tnftumor necrosis factor0.782
Bcl3B-cell leukemia/lymphoma 30.746
Ptenphosphatase and tensin homolog0.617
Rargretinoic acid receptor, gamma0.611
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.575
Ikzf1IKAROS family zinc finger 10.539
Stat2signal transducer and activator of transcription 20.519
Sykbspleen tyrosine kinase0.495
Traf6TNF receptor-associated factor 60.486
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.483
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.458
Tnfrsf11atumor necrosis factor receptor superfamily, member 11a0.439
Cd180CD180 antigen0.418
Bcl6B-cell leukemia/lymphoma 60.406
Foxc1forkhead box C10.385
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.378
Fgfr2fibroblast growth factor receptor 20.345
Ccl4chemokine (C-C motif) ligand 40.339
Traf2TNF receptor-associated factor 20.334
Map3k14mitogen-activated protein kinase kinase kinase 140.315
Sfpi1SFFV proviral integration 10.310
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.307
Psen2presenilin 20.293
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.284
Pou2f2POU domain, class 2, transcription factor 20.276
Mx2myxovirus (influenza virus) resistance 20.271
Ptf1apancreas specific transcription factor, 1a0.262
Dll1delta-like 1 (Drosophila)0.250
Tnfsf11tumor necrosis factor (ligand) superfamily, member 110.228
Tcirg1T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A30.216
Ltalymphotoxin A0.214
FasFas (TNF receptor superfamily member 6)0.203
Map3k7mitogen-activated protein kinase kinase kinase 70.203
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.193
Il10rainterleukin 10 receptor, alpha0.173
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.172
Batfbasic leucine zipper transcription factor, ATF-like0.160
Nfatc2nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 20.157
Batf3basic leucine zipper transcription factor, ATF-like 30.156
Il4rainterleukin 4 receptor, alpha0.156
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.152
Jag1jagged 10.148
Runx1runt related transcription factor 10.140
Vegfavascular endothelial growth factor A0.139
Foxf1aforkhead box F1a0.136
Prkcdprotein kinase C, delta0.132
Cd22CD22 antigen0.131
Stat3signal transducer and activator of transcription 30.131
Birc3baculoviral IAP repeat-containing 30.130
Hspg2perlecan (heparan sulfate proteoglycan 2)0.121
Rag1recombination activating gene 10.115
Apcadenomatosis polyposis coli0.113
Nlrp3NLR family, pyrin domain containing 30.107
Nos2nitric oxide synthase 2, inducible0.102
Esr1estrogen receptor 1 (alpha)0.102
Unc93b1unc-93 homolog B1 (C. elegans)0.092
Irf1interferon regulatory factor 10.091
Pdcd1programmed cell death 10.088
Ciitaclass II transactivator0.084
S1pr2sphingosine-1-phosphate receptor 20.083
Smad4MAD homolog 4 (Drosophila)0.082
Irf7interferon regulatory factor 70.081
Cd79aCD79A antigen (immunoglobulin-associated alpha)0.080
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.077
Irf8interferon regulatory factor 80.077
Ltblymphotoxin B0.076
Ccr7chemokine (C-C motif) receptor 70.074
Smad3MAD homolog 3 (Drosophila)0.073
Ptpn6protein tyrosine phosphatase, non-receptor type 60.072
Gpr132G protein-coupled receptor 1320.069
Tap2transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)0.069
Fbn1fibrillin 10.068
Myd88myeloid differentiation primary response gene 880.068
Kitkit oncogene0.068
Zeb1zinc finger E-box binding homeobox 10.068
Mavsmitochondrial antiviral signaling protein0.065
Uba7ubiquitin-like modifier activating enzyme 70.064
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.063
Relreticuloendotheliosis oncogene0.062
Jak3Janus kinase 30.061
Il2rbinterleukin 2 receptor, beta chain0.060
Inhbainhibin beta-A0.060
Tor3atorsin family 3, member A0.059
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism