The network for 'neuron projection regeneration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

neuron projection regeneration

The regrowth of neuronal processes such as axons or dendrites in response to their loss or damage.

NameDescriptionProbabilityFunc Analog Organism
JUNjun proto-oncogene1.000
FOSFBJ murine osteosarcoma viral oncogene homolog1.000
PTPN1protein tyrosine phosphatase, non-receptor type 10.996
EGFRepidermal growth factor receptor0.992
DHX30DEAH (Asp-Glu-Ala-His) box polypeptide 300.990
CAV1caveolin 1, caveolae protein, 22kDa0.990
CASP8caspase 8, apoptosis-related cysteine peptidase0.986
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.975
JUNBjun B proto-oncogene0.935
ATF3activating transcription factor 30.934
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.919
PTPN11protein tyrosine phosphatase, non-receptor type 110.909
JAK2Janus kinase 20.907
JUNDjun D proto-oncogene0.875
METmet proto-oncogene (hepatocyte growth factor receptor)0.852
INSRinsulin receptor0.843
ATF2activating transcription factor 20.828
IGF1Rinsulin-like growth factor 1 receptor0.811
TIMP2TIMP metallopeptidase inhibitor 20.787
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.757
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.738
STAT1signal transducer and activator of transcription 1, 91kDa0.724
FOSL1FOS-like antigen 10.721
IRF2BP1interferon regulatory factor 2 binding protein 10.689
STRN4striatin, calmodulin binding protein 40.669
DUSP1dual specificity phosphatase 10.654
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.601
CAV2caveolin 20.580
FADDFas (TNFRSF6)-associated via death domain0.527
RARAretinoic acid receptor, alpha0.520
SH2B1SH2B adaptor protein 10.510
ARRB1arrestin, beta 10.508
BCL3B-cell CLL/lymphoma 30.495
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.476
PTCH1patched 10.472
LAMC1laminin, gamma 1 (formerly LAMB2)0.454
EGR1early growth response 10.451
MAP3K1mitogen-activated protein kinase kinase kinase 10.402
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.388
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.384
HMGA2high mobility group AT-hook 20.375
FAT1FAT tumor suppressor homolog 1 (Drosophila)0.365
IFNGR1interferon gamma receptor 10.362
MAPK8mitogen-activated protein kinase 80.354
ATF4activating transcription factor 4 (tax-responsive enhancer element B67)0.347
MAP3K5mitogen-activated protein kinase kinase kinase 50.344
BCL2L1BCL2-like 10.339
BCL2B-cell CLL/lymphoma 20.339
MAP2K4mitogen-activated protein kinase kinase 40.333
EPORerythropoietin receptor0.328
ACTN1actinin, alpha 10.309
TSC22D1TSC22 domain family, member 10.305
SH3RF1SH3 domain containing ring finger 10.300
NR4A2nuclear receptor subfamily 4, group A, member 20.300
ZNF512Bzinc finger protein 512B0.259
FRA10AC1fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 10.256
MAPK10mitogen-activated protein kinase 100.255
NEDD4neural precursor cell expressed, developmentally down-regulated 40.254
AKT1v-akt murine thymoma viral oncogene homolog 10.248
COL4A2collagen, type IV, alpha 20.238
IRS1insulin receptor substrate 10.237
DDIT3DNA-damage-inducible transcript 30.234
MED25mediator complex subunit 250.232
JAK1Janus kinase 10.226
PLAUplasminogen activator, urokinase0.221
SOCS1suppressor of cytokine signaling 10.212
NR4A3nuclear receptor subfamily 4, group A, member 30.211
PTRFpolymerase I and transcript release factor0.209
PDLIM7PDZ and LIM domain 7 (enigma)0.205
COL4A1collagen, type IV, alpha 10.201
FAM40Bfamily with sequence similarity 40, member B0.200
TGIF1TGFB-induced factor homeobox 10.198
KDELR2KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 20.194
ARRB2arrestin, beta 20.191
GRB7growth factor receptor-bound protein 70.189
SYN2synapsin II0.186
LIFleukemia inhibitory factor (cholinergic differentiation factor)0.184
MAPK9mitogen-activated protein kinase 90.183
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.180
RUNX1runt-related transcription factor 10.180
SESN2sestrin 20.177
SOCS3suppressor of cytokine signaling 30.176
NMIN-myc (and STAT) interactor0.175
FOSL2FOS-like antigen 20.175
PRKCDBPprotein kinase C, delta binding protein0.170
PLCG1phospholipase C, gamma 10.168
STAT2signal transducer and activator of transcription 2, 113kDa0.166
STRN3striatin, calmodulin binding protein 30.157
NR4A1nuclear receptor subfamily 4, group A, member 10.154
KDM6Blysine (K)-specific demethylase 6B0.153
NCOR1nuclear receptor corepressor 10.146
LAMB1laminin, beta 10.145
LMAN1lectin, mannose-binding, 10.141
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.140
KLF6Kruppel-like factor 60.131
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.131
STRNstriatin, calmodulin binding protein0.131
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
cdh2cadherin 2, neuronal0.981
alcamaactivated leukocyte cell adhesion molecule a0.947
dag1dystroglycan 10.895
neurodneurogenic differentiation0.832
tbx18T-box 180.721
scn8aasodium channel, voltage-gated, type VIII, alpha a0.659
dpysl5adihydropyrimidinase-like 5a0.655
bocbrother of CDO0.649
ptf1apancreas specific transcription factor, 1a0.646
junbjun B proto-oncogene0.604
tbx2bT-box 2b0.586
dpysl3dihydropyrimidinase-like 30.584
mmp9matrix metalloproteinase 90.548
socs3asuppressor of cytokine signaling 3a0.516
cntn2contactin 20.491
mpzmyelin protein zero0.465
pax2apaired box gene 2a0.436
atoh1aatonal homolog 1a0.407
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.405
smad1MAD homolog 1 (Drosophila)0.392
tbx1T-box 10.349
junjun proto-oncogene0.325
fstl1bfollistatin-like 1b0.317
wnt5bwingless-type MMTV integration site family, member 5b0.311
jag2jagged 20.299
myf5myogenic factor 50.270
dpysl4dihydropyrimidinase-like 40.261
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.256
pou3f2POU class 3 homeobox 20.222
sgk1serum/glucocorticoid regulated kinase 10.214
efna5bephrin A5b0.210
slc1a2bsolute carrier family 1 (glial high affinity glutamate transporter), member 2b0.206
neurod4neurogenic differentiation 40.203
grem2gremlin 2, cysteine knot superfamily0.202
ndrg4N-myc downstream regulated gene 40.195
copebcore promoter element binding protein0.178
junbljun B proto-oncogene, like0.163
arnt2aryl hydrocarbon receptor nuclear translocator 20.158
prkczprotein kinase C, zeta0.154
krt8keratin 80.154
fosl2fos-like antigen 20.152
lamc1laminin, gamma 10.148
dpysl2bdihydropyrimidinase-like 2b0.145
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.144
gad2glutamate decarboxylase 20.143
atf3activating transcription factor 30.136
cntn1acontactin 1a0.127
dlg2discs, large (Drosophila) homolog 20.123
lamb1alaminin, beta 1a0.120
lamb2llaminin, beta 2-like0.116
oprd1bopioid receptor, delta 1b0.113
shhasonic hedgehog a0.107
lmo1LIM domain only 10.106
sema3aasemaphorin 3aa0.104
tcf7l1atranscription factor 7-like 1a (T-cell specific, HMG-box)0.103
m17IL-6 subfamily cytokine M170.102
ephb4beph receptor B4b0.099
ptprkprotein tyrosine phosphatase, receptor type, K0.098
pcdh10bprotocadherin 10b0.098
rargaretinoic acid receptor gamma a0.097
metmet proto-oncogene (hepatocyte growth factor receptor)0.097
evx1even-skipped homeobox 10.096
lama2laminin, alpha 20.092
neurod6aneurogenic differentiation 6a0.084
pdlim1PDZ and LIM domain 1 (elfin)0.084
gro1groucho 10.078
pcdh18bprotocadherin 18b0.075
cdh6cadherin 60.074
jak1Janus kinase 10.073
dlg4discs, large (Drosophila) homolog 4 and discs, large homolog 4 (Drosophila)0.073
csrp1acysteine and glycine-rich protein 1a0.072
chd7chromodomain helicase DNA binding protein 70.071
fli1afriend leukemia integration 1a0.068
aldh1a2aldehyde dehydrogenase 1 family, member A20.067
tln1talin 10.066
insm1ainsulinoma-associated 1a0.066
cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.065
runx1runt-related transcription factor 10.064
slc17a6bsolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6b0.064
notch2notch homolog 20.063
slc17a7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.061
dlg1discs, large (Drosophila) homolog 10.060
mef2dmyocyte enhancer factor 2d0.060
myod1myogenic differentiation 10.059
aldocbaldolase C, fructose-bisphosphate, b0.059
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.058
dbx1bdeveloping brain homeobox 1b0.058
chst11carbohydrate (chondroitin 4) sulfotransferase 110.058
trpm7transient receptor potential cation channel, subfamily M, member 70.058
fzd2frizzled homolog 20.057
nppanatriuretic peptide precursor A0.057
maptbmicrotubule-associated protein tau b0.057
fgf10afibroblast growth factor 10a0.056
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Rac1CG2248 gene product from transcript CG2248-RA0.124
Pi3K92ECG4141 gene product from transcript CG4141-RB0.090
EcREcdysone receptor0.050
DscamDown syndrome cell adhesion molecule0.029
S6kRPS6-p70-protein kinase0.024
CaMKIICalcium/calmodulin-dependent protein kinase II0.023
PP2A-B'CG7913 gene product from transcript CG7913-RK0.022
Mekk1CG7717 gene product from transcript CG7717-RB0.021
Cdc42CG12530 gene product from transcript CG12530-RA0.016
p120ctnAdherens junction protein p1200.015
MED26Mediator complex subunit 260.015
RhebCG1081 gene product from transcript CG1081-RA0.014
InRInsulin-like receptor0.012
aopanterior open0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Efnb2ephrin B20.863
Retret proto-oncogene0.818
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.800
JunJun oncogene0.772
Tgfb2transforming growth factor, beta 20.749
Gli3GLI-Kruppel family member GLI30.416
Ntf3neurotrophin 30.393
Epha4Eph receptor A40.368
Klk1b5kallikrein 1-related peptidase b50.355
Zfp36zinc finger protein 360.337
Foxc1forkhead box C10.336
FosFBJ osteosarcoma oncogene0.336
Hoxa1homeobox A10.318
Bcl2B-cell leukemia/lymphoma 20.312
Klk1b26kallikrein 1-related petidase b260.293
Trp53transformation related protein 530.283
Socs3suppressor of cytokine signaling 30.274
Zfpm2zinc finger protein, multitype 20.260
Pax2paired box gene 20.255
Isl1ISL1 transcription factor, LIM/homeodomain0.232
Ephb2Eph receptor B20.226
Ptk2PTK2 protein tyrosine kinase 20.220
Fgfr1fibroblast growth factor receptor 10.217
Phox2apaired-like homeobox 2a0.199
Klk1kallikrein 10.198
Ywhabtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.196
Klk1b11kallikrein 1-related peptidase b110.181
Stat3signal transducer and activator of transcription 30.173
Ptpn11protein tyrosine phosphatase, non-receptor type 110.172
Enahenabled homolog (Drosophila)0.171
Inainternexin neuronal intermediate filament protein, alpha0.165
Pax3paired box gene 30.162
Ntrk3neurotrophic tyrosine kinase, receptor, type 30.160
Bmp4bone morphogenetic protein 40.159
Tcfap2atranscription factor AP-2, alpha0.151
Mapk14mitogen-activated protein kinase 140.146
Neurod1neurogenic differentiation 10.137
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.121
Pdgfrbplatelet derived growth factor receptor, beta polypeptide0.120
Apoeapolipoprotein E0.118
Klk1b8kallikrein 1-related peptidase b80.117
Nefmneurofilament, medium polypeptide0.117
Klk1b21kallikrein 1-related peptidase b210.115
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.114
Atf3activating transcription factor 30.114
Dusp1dual specificity phosphatase 10.114
Rargretinoic acid receptor, gamma0.113
Klc1kinesin light chain 10.111
Cyr61cysteine rich protein 610.110
Pax6paired box gene 60.103
Lamb1laminin B10.100
Foxc2forkhead box C20.100
Fgfr2fibroblast growth factor receptor 20.098
Nrg1neuregulin 10.093
Irs1insulin receptor substrate 10.092
Klk1b27kallikrein 1-related peptidase b270.092
Rararetinoic acid receptor, alpha0.091
Klk1b24kallikrein 1-related peptidase b240.088
Klk1b1kallikrein 1-related peptidase b10.085
Hand2heart and neural crest derivatives expressed transcript 20.079
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.077
Gdnfglial cell line derived neurotrophic factor0.076
Hey2hairy/enhancer-of-split related with YRPW motif 20.075
Gbx2gastrulation brain homeobox 20.074
Btg2B-cell translocation gene 2, anti-proliferative0.073
Eya1eyes absent 1 homolog (Drosophila)0.072
EvlEna-vasodilator stimulated phosphoprotein0.071
Vaspvasodilator-stimulated phosphoprotein0.070
JunbJun-B oncogene0.070
Bmp1bone morphogenetic protein 10.067
Gfra1glial cell line derived neurotrophic factor family receptor alpha 10.065
Igf1rinsulin-like growth factor I receptor0.059
Prkceprotein kinase C, epsilon0.058
Ptgs2prostaglandin-endoperoxide synthase 20.057
Klk1b3kallikrein 1-related peptidase b30.057
Chd7chromodomain helicase DNA binding protein 70.057
2210010C04RikRIKEN cDNA 2210010C04 gene0.055
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.055
Adamts1a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10.054
Otx2orthodenticle homolog 2 (Drosophila)0.054
Foxg1forkhead box G10.053
Rspo2R-spondin 2 homolog (Xenopus laevis)0.053
Sox11SRY-box containing gene 110.053
Mark1MAP/microtubule affinity-regulating kinase 10.052
LitafLPS-induced TN factor0.051
Acvr1activin A receptor, type 10.051
Klk1b4kallikrein 1-related pepidase b40.048
Fbn2fibrillin 20.047
Bmp7bone morphogenetic protein 70.047
Ppt1palmitoyl-protein thioesterase 10.045
Jag1jagged 10.044
Maffv-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)0.044
Lamc1laminin, gamma 10.044
Itgb1integrin beta 1 (fibronectin receptor beta)0.044
Gli2GLI-Kruppel family member GLI20.043
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Itgb1integrin, beta 10.225
Junbjun B proto-oncogene0.116
JunJun oncogene0.081
Timp1TIMP metallopeptidase inhibitor 10.065
Egr2early growth response 20.056
Lgals3lectin, galactoside-binding, soluble, 30.051
Atf3activating transcription factor 30.050
Gabrg3gamma-aminobutyric acid (GABA) A receptor, gamma 30.048
Eef2eukaryotic translation elongation factor 20.047
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.045
Calcbcalcitonin-related polypeptide, beta0.044
Errfi1ERBB receptor feedback inhibitor 10.042
Ccr1chemokine (C-C motif) receptor 10.042
Klf6Kruppel-like factor 60.039
Btg2BTG family, member 20.039
Usf2upstream transcription factor 2, c-fos interacting0.032
Plaurplasminogen activator, urokinase receptor0.031
Stat6signal transducer and activator of transcription 60.031
Ppypancreatic polypeptide0.030
Slc44a1solute carrier family 44, member 10.030
Fermt2fermitin family homolog 2 (Drosophila)0.029
Nefmneurofilament, medium polypeptide0.029
Zfp36zinc finger protein 360.029
Cd9CD9 molecule0.028
Sncbsynuclein, beta0.028
Cd151CD151 molecule (Raph blood group)0.027
Cst3cystatin C0.027
Hrasls5HRAS-like suppressor family, member 50.027
Foxa3forkhead box A30.026
Rhoqras homolog gene family, member Q0.026
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.025
Runx1runt-related transcription factor 10.025
Hspb1heat shock protein 10.024
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.024
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.023
Gjd2gap junction protein, delta 20.022
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.022
Csf1colony stimulating factor 1 (macrophage)0.021
Tpm2tropomyosin 2, beta0.021
Igfbp5insulin-like growth factor binding protein 50.021
Slc22a1solute carrier family 22 (organic cation transporter), member 10.021
Tnftumor necrosis factor (TNF superfamily, member 2)0.021
Gna12guanine nucleotide binding protein (G protein) alpha 120.020
Anxa4annexin A40.020
Cishcytokine inducible SH2-containing protein0.020
Cd44Cd44 molecule0.020
Crhr1corticotropin releasing hormone receptor 10.020
Unc5bunc-5 homolog B (C. elegans)0.019
Aprtadenine phosphoribosyl transferase0.019
Cd63Cd63 molecule0.019
Msmbmicroseminoprotein, beta0.019
Ednrbendothelin receptor type B0.019
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.018
Adam17ADAM metallopeptidase domain 170.018
Gadd45agrowth arrest and DNA-damage-inducible, alpha0.018
Pmfbp1polyamine modulated factor 1 binding protein 10.018
Slco2b1solute carrier organic anion transporter family, member 2b10.018
Dusp1dual specificity phosphatase 10.018
Carhsp1calcium regulated heat stable protein 10.017
Lilrb3lleukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3-like0.017
Fgfr1Fibroblast growth factor receptor 10.017
Pcyox1prenylcysteine oxidase 10.017
G6pcglucose-6-phosphatase, catalytic subunit0.017
Ier3immediate early response 30.017
Hspa1aheat shock 70kD protein 1A0.017
FosFBJ osteosarcoma oncogene0.017
Neurod2neurogenic differentiation 20.017
Grm6glutamate receptor, metabotropic 60.017
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.016
Ccl2chemokine (C-C motif) ligand 20.016
Cttnbp2nlCTTNBP2 N-terminal like0.016
AhnakAHNAK nucleoprotein0.016
Pdgfbplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.016
Myh10myosin, heavy chain 10, non-muscle0.016
S100a16S100 calcium binding protein A160.016
Sdc3syndecan 30.016
Prrx1paired related homeobox 10.016
Tgfbr2transforming growth factor, beta receptor II0.016
Il6interleukin 60.016
Mmp13matrix metallopeptidase 130.015
Cd99CD99 antigen0.015
Klf4Kruppel-like factor 4 (gut)0.015
Rhobras homolog gene family, member B0.015
S1pr2sphingosine-1-phosphate receptor 20.015
SnrkSNF related kinase0.015
Loxlysyl oxidase0.015
Ddr1discoidin domain receptor tyrosine kinase 10.015
Agtr1aangiotensin II receptor, type 1a0.015
Smad1SMAD family member 10.015
Slc16a3solute carrier family 16, member 3 (monocarboxylic acid transporter 4)0.015
Rxraretinoid X receptor alpha0.015
Lilrb4leukocyte immunoglobulin-like receptor, subfamily B, member 40.015
Emp1epithelial membrane protein 10.014
LOC290595hypothetical gene supported by AF1520020.014
Cxcl6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.014
Pebp1phosphatidylethanolamine binding protein 10.014
Ldlrlow density lipoprotein receptor0.014
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism