The network for 'glutamate metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glutamate metabolic process

The chemical reactions and pathways involving glutamate, the anion of 2-aminopentanedioic acid.

NameDescriptionProbabilityFunc Analog Organism
GGT1gamma-glutamyltransferase 10.999
GGTLC1gamma-glutamyltransferase light chain 10.999
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.991
GCLCglutamate-cysteine ligase, catalytic subunit0.921
GGT2gamma-glutamyltransferase 20.892
GCLMglutamate-cysteine ligase, modifier subunit0.718
VDAC1voltage-dependent anion channel 10.549
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.519
ERBB2IPerbb2 interacting protein0.466
KIF5Bkinesin family member 5B0.359
ATP5BATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.298
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.280
GOT2glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)0.274
STRN3striatin, calmodulin binding protein 30.258
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.247
GLUD1glutamate dehydrogenase 10.223
TOM1L1target of myb1 (chicken)-like 10.206
GLUD2glutamate dehydrogenase 20.169
RCN3reticulocalbin 3, EF-hand calcium binding domain0.156
IDH3Aisocitrate dehydrogenase 3 (NAD+) alpha0.112
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.105
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.093
NDUFS1NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase)0.089
FBXO30F-box protein 300.086
DSTdystonin0.079
GHITMgrowth hormone inducible transmembrane protein0.075
FHfumarate hydratase0.075
BTRCbeta-transducin repeat containing0.057
ATF2activating transcription factor 20.053
ZRANB1zinc finger, RAN-binding domain containing 10.051
ZFP106zinc finger protein 106 homolog (mouse)0.047
GIGYF2GRB10 interacting GYF protein 20.045
MACF1microtubule-actin crosslinking factor 10.041
DNAJA3DnaJ (Hsp40) homolog, subfamily A, member 30.037
RECQL5RecQ protein-like 50.034
ACLYATP citrate lyase0.030
PKP4plakophilin 40.030
YARStyrosyl-tRNA synthetase0.029
RANBP2RAN binding protein 20.029
MDH2malate dehydrogenase 2, NAD (mitochondrial)0.025
MTCH2mitochondrial carrier homolog 2 (C. elegans)0.024
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.023
ME1malic enzyme 1, NADP(+)-dependent, cytosolic0.023
AARSalanyl-tRNA synthetase0.023
AP2B1adaptor-related protein complex 2, beta 1 subunit0.021
SORDsorbitol dehydrogenase0.021
GSRglutathione reductase0.020
SCRIBscribbled homolog (Drosophila)0.020
PEBP1phosphatidylethanolamine binding protein 10.019
TMX2thioredoxin-related transmembrane protein 20.018
CDH1cadherin 1, type 1, E-cadherin (epithelial)0.018
PSEN1presenilin 10.017
NME2non-metastatic cells 2, protein (NM23B) expressed in0.016
COQ9coenzyme Q9 homolog (S. cerevisiae)0.016
PCCBpropionyl CoA carboxylase, beta polypeptide0.016
KIAA1370KIAA13700.016
TCTN3tectonic family member 30.015
ANKRD17ankyrin repeat domain 170.015
SYNE1spectrin repeat containing, nuclear envelope 10.014
MAPRE2microtubule-associated protein, RP/EB family, member 20.014
GLIS2GLIS family zinc finger 20.013
AXIN1axin 10.013
HADHhydroxyacyl-CoA dehydrogenase0.013
HECTD1HECT domain containing 10.013
APOOapolipoprotein O0.013
KIFAP3kinesin-associated protein 30.012
IDEinsulin-degrading enzyme0.012
CALM1calmodulin 1 (phosphorylase kinase, delta)0.012
JUPjunction plakoglobin0.012
CTNNBIP1catenin, beta interacting protein 10.011
MIPEPmitochondrial intermediate peptidase0.011
DLATdihydrolipoamide S-acetyltransferase0.011
SLC25A11solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 110.011
AFG3L2AFG3 ATPase family gene 3-like 2 (S. cerevisiae)0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
ArgkArginine kinase0.383
IdhIsocitrate dehydrogenase0.290
PgmPhosphogluconate mutase0.204
EnoEnolase0.113
Got2Glutamate oxaloacetate transaminase 20.088
AdhAlcohol dehydrogenase0.054
PgdPhosphogluconate dehydrogenase0.048
CG7920CG7920 gene product from transcript CG7920-RA0.046
Hex-AHexokinase A0.033
PyKPyruvate kinase0.030
CG7998CG7998 gene product from transcript CG7998-RA0.029
CG8036CG8036 gene product from transcript CG8036-RB0.023
Ras64BRas oncogene at 64B0.019
ZwZwischenferment0.019
cnncentrosomin0.019
CG5362CG5362 gene product from transcript CG5362-RA0.016
CdsACDP diglyceride synthetase0.015
Act79BActin 79B0.013
CG10570CG10570 gene product from transcript CG10570-RA0.013
squsquash0.013
Cyp12a4CG6042 gene product from transcript CG6042-RA0.012
Syt4Synaptotagmin 40.011
Syt1Synaptotagmin 10.011
eaeaster0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lepleptin0.885
Rxraretinoid X receptor alpha0.733
Leprleptin receptor0.632
Nr1i2nuclear receptor subfamily 1, group I, member 20.345
Apoeapolipoprotein E0.327
Immtinner membrane protein, mitochondrial0.281
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.281
Nos1nitric oxide synthase 1, neuronal0.259
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.248
Gabrdgamma-aminobutyric acid (GABA) A receptor, subunit delta0.230
Smad3MAD homolog 3 (Drosophila)0.212
Tgfb1transforming growth factor, beta 10.196
Nos2nitric oxide synthase 2, inducible0.166
Gpr12G-protein coupled receptor 120.144
Insrinsulin receptor0.135
Esr1estrogen receptor 1 (alpha)0.127
Scd1stearoyl-Coenzyme A desaturase 10.124
Dlg4discs, large homolog 4 (Drosophila)0.122
Nr5a2nuclear receptor subfamily 5, group A, member 20.107
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.105
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.101
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.092
Aldobaldolase B, fructose-bisphosphate0.090
Thrbthyroid hormone receptor beta0.085
Mdh1malate dehydrogenase 1, NAD (soluble)0.084
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.083
Plin1perilipin 10.081
Ppargperoxisome proliferator activated receptor gamma0.079
Hrhairless0.068
Hgdhomogentisate 1, 2-dioxygenase0.063
Cps1carbamoyl-phosphate synthetase 10.062
Nfe2l2nuclear factor, erythroid derived 2, like 20.062
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.060
Rdh16retinol dehydrogenase 160.060
Atp5bATP synthase, H+ transporting mitochondrial F1 complex, beta subunit0.059
Iydiodotyrosine deiodinase0.057
Pipoxpipecolic acid oxidase0.057
Nr0b2nuclear receptor subfamily 0, group B, member 20.056
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.050
Cyp1a2cytochrome P450, family 1, subfamily a, polypeptide 20.049
Klklotho0.049
Syt1synaptotagmin I0.049
Ahcyl1S-adenosylhomocysteine hydrolase-like 10.048
Slc4a4solute carrier family 4 (anion exchanger), member 40.048
Asgr2asialoglycoprotein receptor 20.045
Notch2Notch gene homolog 2 (Drosophila)0.043
Adra1badrenergic receptor, alpha 1b0.043
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.043
Odz1odd Oz/ten-m homolog 1 (Drosophila)0.040
B3galt1UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 10.040
Nlnneurolysin (metallopeptidase M3 family)0.039
Abcc2ATP-binding cassette, sub-family C (CFTR/MRP), member 20.038
Got1glutamate oxaloacetate transaminase 1, soluble0.037
G6pcglucose-6-phosphatase, catalytic0.036
Nos3nitric oxide synthase 3, endothelial cell0.036
Catcatalase0.035
Csf1colony stimulating factor 1 (macrophage)0.034
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.034
Gjb1gap junction protein, beta 10.034
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.033
Mobpmyelin-associated oligodendrocytic basic protein0.032
Vdac1voltage-dependent anion channel 10.032
Bscl2Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)0.032
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.032
Tlr4toll-like receptor 40.031
Irs2insulin receptor substrate 20.031
Echs1enoyl Coenzyme A hydratase, short chain, 1, mitochondrial0.031
Lipelipase, hormone sensitive0.030
Hmgcs13-hydroxy-3-methylglutaryl-Coenzyme A synthase 10.030
Sult1d1sulfotransferase family 1D, member 10.030
Tattyrosine aminotransferase0.030
Gckrglucokinase regulatory protein0.030
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.030
Hccsholocytochrome c synthetase0.030
Abcg5ATP-binding cassette, sub-family G (WHITE), member 50.030
Pcxpyruvate carboxylase0.029
Pnpla2patatin-like phospholipase domain containing 20.029
Npy2rneuropeptide Y receptor Y20.028
Apoa1apolipoprotein A-I0.027
Gpd2glycerol phosphate dehydrogenase 2, mitochondrial0.026
Sik3SIK family kinase 30.026
Ngefneuronal guanine nucleotide exchange factor0.025
Slc26a1solute carrier family 26 (sulfate transporter), member 10.025
Lipalysosomal acid lipase A0.025
Orm3orosomucoid 30.025
Tdo2tryptophan 2,3-dioxygenase0.025
Ldlrlow density lipoprotein receptor0.025
Hnf4ahepatic nuclear factor 4, alpha0.025
Gad2glutamic acid decarboxylase 20.024
Il10interleukin 100.024
Cyp3a13cytochrome P450, family 3, subfamily a, polypeptide 130.024
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.024
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.023
Vav2vav 2 oncogene0.023
Abcb1aATP-binding cassette, sub-family B (MDR/TAP), member 1A0.023
Nr3c1nuclear receptor subfamily 3, group C, member 10.023
Nr1h4nuclear receptor subfamily 1, group H, member 40.023
Acadsacyl-Coenzyme A dehydrogenase, short chain0.023
Plgplasminogen0.023
Sult1b1sulfotransferase family 1B, member 10.022
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.146
TufmTu translation elongation factor, mitochondrial0.050
Nntnicotinamide nucleotide transhydrogenase0.038
Pak2p21 protein (Cdc42/Rac)-activated kinase 20.021
Trap1TNF receptor-associated protein 10.020
Cabc1chaperone, ABC1 activity of bc1 complex homolog (S. pombe)0.016
Mcf2lMCF.2 cell line derived transforming sequence-like0.015
NsfN-ethylmaleimide-sensitive factor0.014
Glud1glutamate dehydrogenase 10.014
G6pcglucose-6-phosphatase, catalytic subunit0.013
Vdac1voltage-dependent anion channel 10.013
Map1lc3bmicrotubule-associated protein 1 light chain 3 beta0.013
Mfn2mitofusin 20.013
Ppa2pyrophosphatase (inorganic) 20.012
Rasgrp1RAS guanyl releasing protein 1 (calcium and DAG-regulated)0.011
Aldh1a1aldehyde dehydrogenase 1 family, member A10.011
Cntn4contactin 40.011
Ldhblactate dehydrogenase B0.011
Ndrg2N-myc downstream regulated gene 20.011
Pahphenylalanine hydroxylase0.011
Chgbchromogranin B0.010
Hibadh3-hydroxyisobutyrate dehydrogenase0.010
Gstt2glutathione S-transferase, theta 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
CCT8Cct8p0.023
PUT1Put1p0.018
FAA2Faa2p0.017
UGA1Uga1p0.015
GDH1Gdh1p0.015
LEU4Leu4p0.015
CPS1Cps1p0.015
ILV6Ilv6p0.015
BDH2Bdh2p0.015
ILV5Ilv5p0.015
GCY1Gcy1p0.014
SMM1Smm1p0.014
FMO1Fmo1p0.012
YLR264C-Ahypothetical protein0.012
NCR1Ncr1p0.012
YHR033Whypothetical protein0.011
LEU2Leu2p0.011
YGP1Ygp1p0.011
SRD1Srd1p0.011
ALD6Ald6p0.011
ARG8Arg8p0.011
NDE1Nde1p0.011
MER1Mer1p0.010
PYC1Pyc1p0.010
YHB1Yhb1p0.010
BOP2Bop2p0.010