The network for 'mitochondrial fission' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitochondrial fission

The division of a mitochondrion within a cell to form two or more separate mitochondrial compartments.

NameDescriptionProbabilityFunc Analog Organism
DNM1Ldynamin 1-like1.000
EGFRepidermal growth factor receptor0.999
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.990
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.888
BNIP3LBCL2/adenovirus E1B 19kDa interacting protein 3-like0.883
BCL2B-cell CLL/lymphoma 20.881
BCL2L11BCL2-like 11 (apoptosis facilitator)0.863
BAXBCL2-associated X protein0.784
BCL2L1BCL2-like 10.784
BAK1BCL2-antagonist/killer 10.599
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.415
MFN2mitofusin 20.340
ZNF746zinc finger protein 7460.267
UBE2R2ubiquitin-conjugating enzyme E2R 20.242
SMCR7LSmith-Magenis syndrome chromosome region, candidate 7-like0.210
MAP1LC3Bmicrotubule-associated protein 1 light chain 3 beta0.208
RNF144Bring finger protein 144B0.158
SMCR7Smith-Magenis syndrome chromosome region, candidate 70.156
FBXO7F-box protein 70.133
SKA3spindle and kinetochore associated complex subunit 30.123
UBASH3Bubiquitin associated and SH3 domain containing B0.114
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.076
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.070
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.065
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.051
SERTAD4SERTA domain containing 40.044
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.043
PSMD7proteasome (prosome, macropain) 26S subunit, non-ATPase, 70.040
PSMD10proteasome (prosome, macropain) 26S subunit, non-ATPase, 100.037
SKA2spindle and kinetochore associated complex subunit 20.037
PSMD11proteasome (prosome, macropain) 26S subunit, non-ATPase, 110.033
FIS1fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)0.030
BIDBH3 interacting domain death agonist0.029
TMEM11transmembrane protein 110.026
PSMD4proteasome (prosome, macropain) 26S subunit, non-ATPase, 40.025
DBN1drebrin 10.021
PIK3R3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.021
GAB2GRB2-associated binding protein 20.021
DLG2discs, large homolog 2 (Drosophila)0.021
MUC1mucin 1, cell surface associated0.021
DLG4discs, large homolog 4 (Drosophila)0.019
USP14ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)0.018
VDAC1voltage-dependent anion channel 10.017
SKA1spindle and kinetochore associated complex subunit 10.017
PMAIP1phorbol-12-myristate-13-acetate-induced protein 10.016
ZC3HAV1zinc finger CCCH-type, antiviral 10.016
GNB5guanine nucleotide binding protein (G protein), beta 50.015
BCAP31B-cell receptor-associated protein 310.015
PSMC6proteasome (prosome, macropain) 26S subunit, ATPase, 60.014
DAXXdeath-domain associated protein0.013
BAG2BCL2-associated athanogene 20.013
ZFAND5zinc finger, AN1-type domain 50.013
VAV3vav 3 guanine nucleotide exchange factor0.013
HDAC6histone deacetylase 60.012
HIPK2homeodomain interacting protein kinase 20.012
INSRinsulin receptor0.012
BIKBCL2-interacting killer (apoptosis-inducing)0.012
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.012
HUWE1HECT, UBA and WWE domain containing 10.012
HAGHhydroxyacylglutathione hydrolase0.011
NBR1neighbor of BRCA1 gene 10.011
PSMD6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.011
ROBO2roundabout, axon guidance receptor, homolog 2 (Drosophila)0.011
DLG3discs, large homolog 3 (Drosophila)0.011
AMBRA1autophagy/beclin-1 regulator 10.011
BADBCL2-associated agonist of cell death0.011
UBASH3Aubiquitin associated and SH3 domain containing A0.010
ZFYVE1zinc finger, FYVE domain containing 10.010
ELK1ELK1, member of ETS oncogene family0.010
PTK6PTK6 protein tyrosine kinase 60.010
UVRAGUV radiation resistance associated gene0.010
MKRN1makorin ring finger protein 10.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
opa1-likeoptic atrophy 1-like0.581
Pink1PTEN-induced putative kinase 10.564
ref(2)Prefractory to sigma P0.259
TER94CG2331 gene product from transcript CG2331-RA0.186
Letm1CG4589 gene product from transcript CG4589-RB0.186
MarfMitochondrial assembly regulatory factor0.152
CG8443CG8443 gene product from transcript CG8443-RA0.081
TBPHCG10327 gene product from transcript CG10327-RC0.072
numbCG3779 gene product from transcript CG3779-RB0.072
trpmltransient receptor potential mucolipin0.064
Sin3ACG8815 gene product from transcript CG8815-RC0.060
drddrop dead0.051
ThorCG8846 gene product from transcript CG8846-RA0.046
chicoCG5686 gene product from transcript CG5686-RB0.043
Atg1Autophagy-specific gene 10.038
pAbppolyA-binding protein0.035
Rho1CG8416 gene product from transcript CG8416-RB0.033
ash2absent, small, or homeotic discs 20.033
Npc1aNiemann-Pick type C-1a0.030
fwdfour wheel drive0.026
Drp1Dynamin related protein 10.026
sxcsuper sex combs0.025
CG8709CG8709 gene product from transcript CG8709-RK0.023
Atg6Autophagy-specific gene 60.020
CG11299CG11299 gene product from transcript CG11299-RA0.020
Ppat-DpckBifunctional Phosphopantetheine adenylyltransferase - Dephospho-CoA kinase0.018
HtrA2CG8464 gene product from transcript CG8464-RA0.018
RagACG11968 gene product from transcript CG11968-RA0.018
CG15609CG15609 gene product from transcript CG15609-RE0.017
coroCG9446 gene product from transcript CG9446-RC0.015
LaspCG3849 gene product from transcript CG3849-RB0.014
Ube3aUbiquitin protein ligase E3A0.014
CG7145CG7145 gene product from transcript CG7145-RD0.014
MiroMitochondrial Rho0.014
Cf2Chorion factor 20.014
certceramide transfer protein0.013
Pk61CProtein kinase 61C0.013
SaraSmad anchor for receptor activation0.013
CG4603CG4603 gene product from transcript CG4603-RA0.013
Vha100-1CG1709 gene product from transcript CG1709-RF0.012
InvadolysinCG3953 gene product from transcript CG3953-RA0.012
CG1347CG1347 gene product from transcript CG1347-RB0.012
Itp-r83AInositol 1,4,5,-tris-phosphate receptor0.012
Hsc70-5Heat shock protein cognate 50.012
Gp150CG5820 gene product from transcript CG5820-RA0.011
Pp2A-29BProtein phosphatase 2A at 29B0.011
18w18 wheeler0.011
Tpr2Tetratricopeptide repeat protein 20.011
LanALaminin A0.011
Vps35Vacuolar protein sorting 350.011
DNApol-gamma35DNA polymerase gamma 35kD0.010
CG31133CG31133 gene product from transcript CG31133-RA0.010
Cdc27CG8610 gene product from transcript CG8610-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Bak1BCL2-antagonist/killer 10.205
Atg12autophagy-related 12 (yeast)0.053
5430411K18RikRIKEN cDNA 5430411K18 gene0.029
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.025
Lrrk2leucine-rich repeat kinase 20.018
Ap2s1adaptor-related protein complex 2, sigma 1 subunit0.014
Atp6v1dATPase, H+ transporting, lysosomal V1 subunit D0.014
Mfn2mitofusin 20.013
Grsf1G-rich RNA sequence binding factor 10.013
Slc30a9solute carrier family 30 (zinc transporter), member 90.012
Abhd5abhydrolase domain containing 50.012
Bcl2B-cell leukemia/lymphoma 20.012
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
YLR264C-Ahypothetical protein0.010