The network for 'centrosome duplication' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

centrosome duplication

The replication of a centrosome, a structure comprised of a pair of centrioles and peri-centriolar material from which a microtubule spindle apparatus is organized.

NameDescriptionProbabilityFunc Analog Organism
NEURL4neuralized homolog 4 (Drosophila)0.752
RPL18ribosomal protein L180.671
CCT4chaperonin containing TCP1, subunit 4 (delta)0.600
CCT8chaperonin containing TCP1, subunit 8 (theta)0.599
RPL17ribosomal protein L170.594
STILSCL/TAL1 interrupting locus0.589
CENPJcentromere protein J0.558
CUL1cullin 10.437
HSP90AA1heat shock protein 90kDa alpha (cytosolic), class A member 10.365
RPL32ribosomal protein L320.342
CDC25Acell division cycle 25 homolog A (S. pombe)0.334
FBXW11F-box and WD repeat domain containing 110.297
RPL8ribosomal protein L80.290
RPS18ribosomal protein S180.282
RPL31ribosomal protein L310.280
SASS6spindle assembly 6 homolog (C. elegans)0.276
RPL23ribosomal protein L230.270
RPL19ribosomal protein L190.257
RPLP0ribosomal protein, large, P00.252
RPL21ribosomal protein L210.243
CEP135centrosomal protein 135kDa0.223
RPL6ribosomal protein L60.223
CDK1cyclin-dependent kinase 10.222
RPL7Aribosomal protein L7a0.211
RPL27Aribosomal protein L27a0.207
RPL29ribosomal protein L290.206
EEF1A1eukaryotic translation elongation factor 1 alpha 10.201
BIRC5baculoviral IAP repeat containing 50.191
RPL22ribosomal protein L220.185
RPL24ribosomal protein L240.165
RPS17ribosomal protein S170.164
RPS6ribosomal protein S60.153
AURKBaurora kinase B0.148
RPL41ribosomal protein L410.142
CCNB1cyclin B10.141
AURKAaurora kinase A0.140
RPS20ribosomal protein S200.134
PRC1protein regulator of cytokinesis 10.128
RPL9ribosomal protein L90.122
BTRCbeta-transducin repeat containing0.120
KIF23kinesin family member 230.120
RPS16ribosomal protein S160.118
RPL10ribosomal protein L100.116
LIN9lin-9 homolog (C. elegans)0.115
RPL3ribosomal protein L30.112
WEE1WEE1 homolog (S. pombe)0.108
PPP2CBprotein phosphatase 2, catalytic subunit, beta isozyme0.108
CKS1BCDC28 protein kinase regulatory subunit 1B0.106
RPL12ribosomal protein L120.104
RANRAN, member RAS oncogene family0.100
EEF1Geukaryotic translation elongation factor 1 gamma0.099
RPS21ribosomal protein S210.097
RPL7ribosomal protein L70.097
CCNA2cyclin A20.093
RPL5ribosomal protein L50.092
CCNFcyclin F0.088
TCP1t-complex 10.086
RPL14ribosomal protein L140.084
RPS10ribosomal protein S100.075
RPS19ribosomal protein S190.075
RPL10Aribosomal protein L10a0.074
RPS3ribosomal protein S30.071
CKAP5cytoskeleton associated protein 50.067
FOXM1forkhead box M10.066
RPL30ribosomal protein L300.065
C19orf39chromosome 19 open reading frame 390.060
RPL27ribosomal protein L270.058
CCNB2cyclin B20.057
NLKnemo-like kinase0.057
RPS28ribosomal protein S280.057
TACC3transforming, acidic coiled-coil containing protein 30.057
RPS27Aribosomal protein S27a0.056
RPS4Xribosomal protein S4, X-linked0.056
RPL13ribosomal protein L130.056
GTSE1G-2 and S-phase expressed 10.056
XPO1exportin 1 (CRM1 homolog, yeast)0.054
CCNE1cyclin E10.053
MDM2Mdm2 p53 binding protein homolog (mouse)0.053
TJP1tight junction protein 1 (zona occludens 1)0.052
UBA52ubiquitin A-52 residue ribosomal protein fusion product 10.052
PBKPDZ binding kinase0.050
RAD51AP1RAD51 associated protein 10.049
RPS3Aribosomal protein S3A0.047
KIF4Akinesin family member 4A0.045
RPS13ribosomal protein S130.044
CENPFcentromere protein F, 350/400kDa (mitosin)0.044
RPL13Aribosomal protein L13a0.043
INCENPinner centromere protein antigens 135/155kDa0.042
CDC20cell division cycle 20 homolog (S. cerevisiae)0.041
PLK1polo-like kinase 10.041
SKP2S-phase kinase-associated protein 2 (p45)0.040
RPL15ribosomal protein L150.040
RPLP1ribosomal protein, large, P10.039
SMC6structural maintenance of chromosomes 60.039
RPL4ribosomal protein L40.039
TPX2TPX2, microtubule-associated, homolog (Xenopus laevis)0.038
RPS11ribosomal protein S110.036
SMC4structural maintenance of chromosomes 40.036
STARD9StAR-related lipid transfer (START) domain containing 90.035
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
rpl19ribosomal protein L190.973
rpl12ribosomal protein L120.971
rpl4ribosomal protein L40.969
rpl9ribosomal protein L90.925
rpl6ribosomal protein L60.903
rps4xribosomal protein S4, X-linked0.895
rpl23aribosomal protein L23a0.892
rpl8ribosomal protein L80.880
rps18ribosomal protein S180.824
rps3aribosomal protein S3A0.812
rpl36aribosomal protein L36A0.802
kif11kinesin family member 110.774
rpl13ribosomal protein L130.771
stilTAL1 (SCL) interrupting locus0.755
rpl34ribosomal protein L340.655
rpl10ribosomal protein L100.641
rpl11ribosomal protein L110.628
rpl28ribosomal protein L280.618
g2e3G2/M-phase specific E3 ubiquitin ligase0.587
nusap1nucleolar and spindle associated protein 10.568
krcpkelch repeat-containing protein0.525
rpl15ribosomal protein L150.516
rpl23ribosomal protein L230.511
rpl18aribosomal protein L18a0.510
rps8aribosomal protein S8a0.472
rps7ribosomal protein S70.470
rpl35aribosomal protein L35a0.451
rpl21ribosomal protein L210.421
rpl3ribosomal protein L30.417
rps5ribosomal protein S50.408
rps10ribosomal protein S100.345
rps11ribosomal protein S110.340
top2atopoisomerase (DNA) II alpha0.337
rpl7ribosomal protein L70.330
eef1geukaryotic translation elongation factor 1 gamma0.326
cdc20cell division cycle 20 homolog0.324
pif1PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)0.324
rpl30ribosomal protein L300.299
plk1polo-like kinase 1 (Drosophila)0.286
rplp0ribosomal protein, large, P00.260
kifc1kinesin family member C10.230
eef1b2eukaryotic translation elongation factor 1 beta 20.227
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.211
ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.207
gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 10.203
sass6spindle assembly 6 homolog (C. elegans)0.203
ticrrTopBP1-interacting, checkpoint, and replication regulator0.202
gmnngeminin, DNA replication inhibitor0.158
cdk2cyclin-dependent kinase 20.156
eif5aeukaryotic translation initiation factor 5A0.151
cep55lcentrosomal protein 55 like0.147
rtkn2rhotekin 20.139
wdhd1WD repeat and HMG-box DNA binding protein 10.134
arhgap11aRho GTPase activating protein 11A0.133
eif3s2eukaryotic translation initiation factor 3, subunit 2 beta0.129
skp2S-phase kinase-associated protein 2 (p45)0.127
rps29ribosomal protein S290.126
rpl27ribosomal protein L270.125
rpsaribosomal protein SA0.122
rpl13aribosomal protein L13a0.116
rpl35ribosomal protein L350.115
chaf1bchromatin assembly factor 1, subunit B0.113
kif23kinesin family member 230.109
rps24ribosomal protein S240.108
rps14ribosomal protein S140.108
slbpstem-loop binding protein0.098
cdc25cell division cycle 25 homolog0.090
mki67ipmki67 (FHA domain) interacting nucleolar phosphoprotein (human)0.089
ssr4signal sequence receptor, delta0.087
esco2establishment of cohesion 1 homolog 20.086
ttkttk protein kinase0.085
aurkbaurora kinase B0.085
rpl37ribosomal protein L370.082
rpl5aribosomal protein L5a0.082
tpt1tumor protein, translationally-controlled 10.080
rab22aRAB22A, member RAS oncogene family0.080
tacc3transforming, acidic coiled-coil containing protein 30.079
plk4polo-like kinase 4 (Drosophila)0.077
rpl5bribosomal protein L5b0.075
rps15ribosomal protein S150.074
clk4aCDC-like kinase 4a0.071
mybl2myeloblastosis oncogene-like 20.067
btf3basic transcription factor 30.066
rpl26ribosomal protein L260.064
gnl3guanine nucleotide binding protein-like 3 (nucleolar)0.063
eif3eaeukaryotic translation initiation factor 3, subunit E, a0.062
ccna2cyclin A20.061
celsr1acadherin EGF LAG seven-pass G-type receptor 1a0.061
mad2l1MAD2 mitotic arrest deficient-like 1 (yeast)0.060
ube2i2ubiquitin-conjugating enzyme E2I20.060
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Klp67AKinesin-like protein at 67A0.999
Klp10ACG1453 gene product from transcript CG1453-RA0.998
Klp61FKinesin-like protein at 61F0.993
Sas-4CG10061 gene product from transcript CG10061-RA0.991
BubR1Bub1-related kinase0.974
RpL18ARibosomal protein L18A0.971
marsCG17064 gene product from transcript CG17064-RB0.954
RpS7Ribosomal protein S70.945
Poc1Proteome of centrioles 10.933
RpL4Ribosomal protein L40.929
poloCG12306 gene product from transcript CG12306-RA0.920
RpL7ARibosomal protein L7A0.919
RpL27Ribosomal protein L270.913
RpS13Ribosomal protein S130.905
RpS24Ribosomal protein S240.904
RpL32Ribosomal protein L320.892
RpL28Ribosomal protein L280.892
ana2anastral spindle 20.874
ana3anastral spindle 30.868
Nek2CG17256 gene product from transcript CG17256-RA0.862
Ef2bElongation factor 2b0.861
RpL7Ribosomal protein L70.860
RpS4Ribosomal protein S40.858
RpS16Ribosomal protein S160.844
RpL3Ribosomal protein L30.838
lkb1CG9374 gene product from transcript CG9374-RJ0.823
RpL21Ribosomal protein L210.822
SAKSak kinase0.821
RpS26Ribosomal protein S260.820
Grip75CG6176 gene product from transcript CG6176-RA0.813
tacctransforming acidic coiled-coil protein0.812
RpS25Ribosomal protein S250.809
CG5690CG5690 gene product from transcript CG5690-RA0.773
Cp110CG14617 gene product from transcript CG14617-RB0.750
oho23Bovergrown hematopoietic organs at 23B0.749
chbchromosome bows0.730
RpS11Ribosomal protein S110.720
RpL13Ribosomal protein L130.707
RpL29Ribosomal protein L290.690
sopstring of pearls0.684
His2A:CG33838CG33838 gene product from transcript CG33838-RA0.645
RpL12Ribosomal protein L120.642
Cep135CG17081 gene product from transcript CG17081-RB0.638
Pak3CG14895 gene product from transcript CG14895-RA0.638
RpS15Ribosomal protein S150.636
RpL6Ribosomal protein L60.632
RpL22Ribosomal protein L220.629
RpS27Ribosomal protein S270.604
aspabnormal spindle0.593
RpL26Ribosomal protein L260.585
RpL34bRibosomal protein L34b0.583
RpS28bRibosomal protein S28b0.563
His2A:CG31618CG31618 gene product from transcript CG31618-RA0.556
RpL40Ribosomal protein L400.552
Nup358Nucleoporin 3580.547
RpS23Ribosomal protein S230.546
RpL17Ribosomal protein L170.543
ctpcut up0.524
MioMlx interactor0.505
RpL11Ribosomal protein L110.496
Rab5Rab-protein 50.480
RpS5aRibosomal protein S5a0.478
RpL35ARibosomal protein L35A0.476
Rack1Receptor of activated protein kinase C 10.474
RpL37aRibosomal protein L37a0.461
Sgt1CG9617 gene product from transcript CG9617-RA0.442
His2A:CG33835CG33835 gene product from transcript CG33835-RA0.442
His2A:CG33853CG33853 gene product from transcript CG33853-RA0.424
His2A:CG33808CG33808 gene product from transcript CG33808-RA0.424
His2A:CG33820CG33820 gene product from transcript CG33820-RA0.418
His2A:CG33823CG33823 gene product from transcript CG33823-RA0.418
RpL10AbRibosomal protein L10Ab0.411
His2A:CG33829CG33829 gene product from transcript CG33829-RA0.405
His2A:CG33859CG33859 gene product from transcript CG33859-RA0.405
His2A:CG33832CG33832 gene product from transcript CG33832-RA0.405
His2A:CG33826CG33826 gene product from transcript CG33826-RA0.405
CycECyclin E0.405
RpS18Ribosomal protein S180.402
CG6758CG6758 gene product from transcript CG6758-RA0.398
His2A:CG33856CG33856 gene product from transcript CG33856-RA0.396
thrthree rows0.384
RpS12Ribosomal protein S120.373
RpS8Ribosomal protein S80.370
RpL5Ribosomal protein L50.369
RpLP2Ribosomal protein LP20.364
RpS30Ribosomal protein S300.358
RpS9Ribosomal protein S90.353
His4:CG33879CG33879 gene product from transcript CG33879-RA0.348
CG8478CG8478 gene product from transcript CG8478-RD0.345
His2A:CG33841CG33841 gene product from transcript CG33841-RA0.342
RpL18Ribosomal protein L180.342
His2A:CG33844CG33844 gene product from transcript CG33844-RA0.340
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Cdc25ccell division cycle 25 homolog C (S. pombe)0.994
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.887
Kif4kinesin family member 40.696
Plk1polo-like kinase 1 (Drosophila)0.660
Brca1breast cancer 10.553
Anlnanillin, actin binding protein0.512
Kif20akinesin family member 20A0.501
Cdc20cell division cycle 20 homolog (S. cerevisiae)0.418
Ccnb1cyclin B10.417
Ccna2cyclin A20.362
Kif11kinesin family member 110.338
Rplp0ribosomal protein, large, P00.319
Prc1protein regulator of cytokinesis 10.298
Spag5sperm associated antigen 50.297
Ccnb2cyclin B20.296
Aurkaaurora kinase A0.245
Cdk1cyclin-dependent kinase 10.242
Hspa8heat shock protein 80.228
Kif2ckinesin family member 2C0.216
Gtse1G two S phase expressed protein 10.205
Dlgap5discs, large (Drosophila) homolog-associated protein 50.192
Aurkbaurora kinase B0.187
Tacc3transforming, acidic coiled-coil containing protein 30.186
Cdc25bcell division cycle 25 homolog B (S. pombe)0.171
Cep55centrosomal protein 550.163
Ndc80NDC80 homolog, kinetochore complex component (S. cerevisiae)0.147
TtkTtk protein kinase0.143
Plk4polo-like kinase 4 (Drosophila)0.143
Nek2NIMA (never in mitosis gene a)-related expressed kinase 20.142
Incenpinner centromere protein0.136
Hsp90aa1heat shock protein 90, alpha (cytosolic), class A member 10.126
Ccnfcyclin F0.124
Aspmasp (abnormal spindle)-like, microcephaly associated (Drosophila)0.115
Bub1budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)0.109
Mis18bp1MIS18 binding protein 10.103
Ckap2cytoskeleton associated protein 20.103
Mxd3Max dimerization protein 30.096
Top2atopoisomerase (DNA) II alpha0.095
Rad51ap1RAD51 associated protein 10.094
Cdca5cell division cycle associated 50.092
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.089
Kif23kinesin family member 230.087
Ccdc99coiled-coil domain containing 990.086
Ube2cubiquitin-conjugating enzyme E2C0.082
Smc4structural maintenance of chromosomes 40.077
BlmBloom syndrome, RecQ helicase-like0.072
Kif22kinesin family member 220.071
Birc5baculoviral IAP repeat-containing 50.070
Fam64afamily with sequence similarity 64, member A0.065
Cdkn3cyclin-dependent kinase inhibitor 30.064
C330027C09RikRIKEN cDNA C330027C09 gene0.063
Mns1meiosis-specific nuclear structural protein 10.062
Strn3striatin, calmodulin binding protein 30.061
Gsg2germ cell-specific gene 20.060
Cdc7cell division cycle 7 (S. cerevisiae)0.058
Cdt1chromatin licensing and DNA replication factor 10.057
Hmmrhyaluronan mediated motility receptor (RHAMM)0.055
Per2period homolog 2 (Drosophila)0.055
Racgap1Rac GTPase-activating protein 10.054
Arhgap21Rho GTPase activating protein 210.054
Ncaphnon-SMC condensin I complex, subunit H0.051
Sass6spindle assembly 6 homolog (C. elegans)0.051
Gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2 like 10.051
Chaf1bchromatin assembly factor 1, subunit B (p60)0.051
Rabep1rabaptin, RAB GTPase binding effector protein 10.050
Rasa1RAS p21 protein activator 10.049
Chordc1cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 10.048
Cdca8cell division cycle associated 80.047
Chek1checkpoint kinase 1 homolog (S. pombe)0.047
Usp9xubiquitin specific peptidase 9, X chromosome0.044
Wdhd1WD repeat and HMG-box DNA binding protein 10.044
Ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.043
Kif2akinesin family member 2A0.042
E2f8E2F transcription factor 80.040
Iqgap3IQ motif containing GTPase activating protein 30.040
Ireb2iron responsive element binding protein 20.039
Dtldenticleless homolog (Drosophila)0.039
Tcp1t-complex protein 10.039
H2afxH2A histone family, member X0.038
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.037
StilScl/Tal1 interrupting locus0.037
Lmnb1lamin B10.037
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.036
Rps3aribosomal protein S3A0.036
Foxm1forkhead box M10.035
Eea1early endosome antigen 10.034
Kif5bkinesin family member 5B0.034
Cenpfcentromere protein F0.034
Cks2CDC28 protein kinase regulatory subunit 20.033
Cenpecentromere protein E0.032
Cul3cullin 30.032
Haus5HAUS augmin-like complex, subunit 50.032
Cenpncentromere protein N0.031
Wdr26WD repeat domain 260.030
Sgol1shugoshin-like 1 (S. pombe)0.030
LOC10004462760S ribosomal protein L23-like0.030
Exo1exonuclease 10.030
Brsk1BR serine/threonine kinase 10.029
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism