The network for 'negative regulation of lipid transport' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

negative regulation of lipid transport

Any process that stops, prevents, or reduces the frequency, rate or extent of the directed movement of lipids into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

NameDescriptionProbabilityFunc Analog Organism
ITGB1integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)0.998
TLN1talin 10.938
FN1fibronectin 10.762
INSRinsulin receptor0.620
GRB10growth factor receptor-bound protein 100.590
FHL2four and a half LIM domains 20.511
APOA1apolipoprotein A-I0.411
PTPN1protein tyrosine phosphatase, non-receptor type 10.349
TGFB1transforming growth factor, beta 10.259
GAB1GRB2-associated binding protein 10.256
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.229
ITGB4integrin, beta 40.221
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.211
APOC1apolipoprotein C-I0.181
ITGAVintegrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)0.160
APOEapolipoprotein E0.153
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.139
RARAretinoic acid receptor, alpha0.121
IGF1Rinsulin-like growth factor 1 receptor0.119
TGM2transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)0.117
MAPTmicrotubule-associated protein tau0.116
IRS1insulin receptor substrate 10.094
NCF1neutrophil cytosolic factor 10.086
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.085
APOA2apolipoprotein A-II0.084
FLNAfilamin A, alpha0.082
MED15mediator complex subunit 150.082
SPG20spastic paraplegia 20 (Troyer syndrome)0.078
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.075
LCATlecithin-cholesterol acyltransferase0.067
PDIA3protein disulfide isomerase family A, member 30.067
SMPD1sphingomyelin phosphodiesterase 1, acid lysosomal0.062
CTGFconnective tissue growth factor0.062
APOC3apolipoprotein C-III0.062
THBS1thrombospondin 10.060
GAB2GRB2-associated binding protein 20.058
CD63CD63 molecule0.056
CYP4F2cytochrome P450, family 4, subfamily F, polypeptide 20.050
FOXO1forkhead box O10.043
NEDD9neural precursor cell expressed, developmentally down-regulated 90.043
PDK1pyruvate dehydrogenase kinase, isozyme 10.043
FRS2fibroblast growth factor receptor substrate 20.043
MED25mediator complex subunit 250.042
RXRAretinoid X receptor, alpha0.040
PTPN6protein tyrosine phosphatase, non-receptor type 60.038
PELI3pellino homolog 3 (Drosophila)0.035
PRKCBprotein kinase C, beta0.035
HNF4Ahepatocyte nuclear factor 4, alpha0.035
CCDC115coiled-coil domain containing 1150.033
DTX1deltex homolog 1 (Drosophila)0.033
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.033
APOBapolipoprotein B (including Ag(x) antigen)0.031
CDCP1CUB domain containing protein 10.030
APOC2apolipoprotein C-II0.029
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.028
PRKCZprotein kinase C, zeta0.026
MTORmechanistic target of rapamycin (serine/threonine kinase)0.026
PDPK13-phosphoinositide dependent protein kinase-10.025
ITGA2integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)0.024
PRKCAprotein kinase C, alpha0.022
CYP4F12cytochrome P450, family 4, subfamily F, polypeptide 120.021
LDLRlow density lipoprotein receptor0.021
CBLCCas-Br-M (murine) ecotropic retroviral transforming sequence c0.020
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.020
TSC22D1TSC22 domain family, member 10.020
ITGA6integrin, alpha 60.019
ITGB5integrin, beta 50.019
FOXO3forkhead box O30.019
PALLDpalladin, cytoskeletal associated protein0.018
SH3RF1SH3 domain containing ring finger 10.018
CYBAcytochrome b-245, alpha polypeptide0.017
CARD11caspase recruitment domain family, member 110.016
PICK1protein interacting with PRKCA 10.016
IRAK4interleukin-1 receptor-associated kinase 40.016
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.016
IRS2insulin receptor substrate 20.015
TNFRSF10Ctumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain0.015
TRIM9tripartite motif containing 90.014
BADBCL2-associated agonist of cell death0.014
CYP4F3cytochrome P450, family 4, subfamily F, polypeptide 30.014
CD9CD9 molecule0.014
CAV1caveolin 1, caveolae protein, 22kDa0.014
COL1A1collagen, type I, alpha 10.014
MPZL1myelin protein zero-like 10.014
CYP3A43cytochrome P450, family 3, subfamily A, polypeptide 430.013
PECAM1platelet/endothelial cell adhesion molecule0.013
IRAK3interleukin-1 receptor-associated kinase 30.012
NCOA1nuclear receptor coactivator 10.012
STAT5Bsignal transducer and activator of transcription 5B0.012
DSEdermatan sulfate epimerase0.012
FYNFYN oncogene related to SRC, FGR, YES0.012
SORBS2sorbin and SH3 domain containing 20.012
SNX9sorting nexin 90.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Per2period homolog 2 (Drosophila)0.931
Arntlaryl hydrocarbon receptor nuclear translocator-like0.904
Abca1ATP-binding cassette, sub-family A (ABC1), member 10.868
Clockcircadian locomotor output cycles kaput0.867
Amhr2anti-Mullerian hormone type 2 receptor0.444
Fgfr2fibroblast growth factor receptor 20.224
Nos3nitric oxide synthase 3, endothelial cell0.209
Per1period homolog 1 (Drosophila)0.207
Leprleptin receptor0.205
Cry1cryptochrome 1 (photolyase-like)0.194
Cry2cryptochrome 2 (photolyase-like)0.143
Rxraretinoid X receptor alpha0.132
Traf6TNF receptor-associated factor 60.109
Npc1Niemann Pick type C10.102
Ctnnb1catenin (cadherin associated protein), beta 10.087
Nr5a1nuclear receptor subfamily 5, group A, member 10.081
Mapk8ip1mitogen-activated protein kinase 8 interacting protein 10.080
Shhsonic hedgehog0.074
Arandrogen receptor0.073
Lrp2low density lipoprotein receptor-related protein 20.052
Lyz2lysozyme 20.047
Ppargperoxisome proliferator activated receptor gamma0.044
Ghrgrowth hormone receptor0.042
Egfrepidermal growth factor receptor0.039
Esr1estrogen receptor 1 (alpha)0.034
Col1a1collagen, type I, alpha 10.030
Axin1axin 10.028
Fgfr3fibroblast growth factor receptor 30.027
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.026
Myd88myeloid differentiation primary response gene 880.024
Itgb1integrin beta 1 (fibronectin receptor beta)0.024
Gli3GLI-Kruppel family member GLI30.023
Ldlrlow density lipoprotein receptor0.022
Ptenphosphatase and tensin homolog0.022
Abcg5ATP-binding cassette, sub-family G (WHITE), member 50.021
Fshrfollicle stimulating hormone receptor0.021
Ndst1N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 10.020
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.018
Loxlysyl oxidase0.018
Slc22a2solute carrier family 22 (organic cation transporter), member 20.018
Kiss1KiSS-1 metastasis-suppressor0.018
Gata4GATA binding protein 40.017
Tbx3T-box 30.017
Mertkc-mer proto-oncogene tyrosine kinase0.016
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.016
Akt2thymoma viral proto-oncogene 20.016
Per3period homolog 3 (Drosophila)0.015
Insrinsulin receptor0.015
Irak4interleukin-1 receptor-associated kinase 40.015
Bmp4bone morphogenetic protein 40.015
Abcg8ATP-binding cassette, sub-family G (WHITE), member 80.014
IhhIndian hedgehog0.014
Zp2zona pellucida glycoprotein 20.013
Runx2runt related transcription factor 20.013
Il1r1interleukin 1 receptor, type I0.013
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.013
Pitx2paired-like homeodomain transcription factor 20.012
Igf1insulin-like growth factor 10.012
Pick1protein interacting with C kinase 10.012
Fgf9fibroblast growth factor 90.012
Lmnalamin A0.012
Srfserum response factor0.012
Nr6a1nuclear receptor subfamily 6, group A, member 10.011
Gnrh1gonadotropin releasing hormone 10.011
Dab2disabled homolog 2 (Drosophila)0.011
Pkd1polycystic kidney disease 1 homolog0.011
Cfhcomplement component factor h0.011
Mep1ameprin 1 alpha0.011
Agtr2angiotensin II receptor, type 20.010
Lhcgrluteinizing hormone/choriogonadotropin receptor0.010
Ctdnep1CTD nuclear envelope phosphatase 10.010
Cav1caveolin 1, caveolae protein0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism