The network for 'cellular response to hydrogen peroxide' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

cellular response to hydrogen peroxide

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.

NameDescriptionProbabilityFunc Analog Organism
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.997
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.997
HBBhemoglobin, beta0.964
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.928
PRDX1peroxiredoxin 10.920
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.915
JUNjun proto-oncogene0.888
HBA2hemoglobin, alpha 20.856
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.769
SERPINE1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.755
MPDZmultiple PDZ domain protein0.733
MAFGv-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)0.708
PRDX4peroxiredoxin 40.696
BCL3B-cell CLL/lymphoma 30.657
HBG2hemoglobin, gamma G0.645
SOD1superoxide dismutase 1, soluble0.615
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.599
DAXXdeath-domain associated protein0.591
PLAUplasminogen activator, urokinase0.539
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.448
EGFRepidermal growth factor receptor0.420
MAP3K8mitogen-activated protein kinase kinase kinase 80.414
ARHGAP1Rho GTPase activating protein 10.387
DUSP1dual specificity phosphatase 10.386
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.340
MAPTmicrotubule-associated protein tau0.307
PRDX2peroxiredoxin 20.300
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.300
NFE2L2nuclear factor (erythroid-derived 2)-like 20.292
CAV1caveolin 1, caveolae protein, 22kDa0.271
PPP1R15Aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.267
TNFAIP1tumor necrosis factor, alpha-induced protein 1 (endothelial)0.262
IL4Rinterleukin 4 receptor0.251
KLF6Kruppel-like factor 60.239
PRKAB1protein kinase, AMP-activated, beta 1 non-catalytic subunit0.234
RHOAras homolog gene family, member A0.229
GAB1GRB2-associated binding protein 10.220
ACACAacetyl-CoA carboxylase alpha0.208
PARK7Parkinson disease (autosomal recessive, early onset) 70.194
MAFFv-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)0.193
PMLpromyelocytic leukemia0.193
METmet proto-oncogene (hepatocyte growth factor receptor)0.185
ATF3activating transcription factor 30.185
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.172
TSC22D4TSC22 domain family, member 40.160
RUNX1runt-related transcription factor 10.158
FOSFBJ murine osteosarcoma viral oncogene homolog0.151
TNIP2TNFAIP3 interacting protein 20.151
APOEapolipoprotein E0.146
RING1ring finger protein 10.144
PLAURplasminogen activator, urokinase receptor0.143
GPX4glutathione peroxidase 4 (phospholipid hydroperoxidase)0.139
SOCS1suppressor of cytokine signaling 10.135
FBXO7F-box protein 70.135
S100BS100 calcium binding protein B0.123
EP300E1A binding protein p3000.121
ARandrogen receptor0.110
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.107
MAP3K5mitogen-activated protein kinase kinase kinase 50.103
FADDFas (TNFRSF6)-associated via death domain0.101
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.100
COL4A2collagen, type IV, alpha 20.096
NR4A1nuclear receptor subfamily 4, group A, member 10.091
KAT2BK(lysine) acetyltransferase 2B0.091
PLXNB1plexin B10.090
PRKAB2protein kinase, AMP-activated, beta 2 non-catalytic subunit0.086
CTSDcathepsin D0.086
NCOR2nuclear receptor corepressor 20.083
PGK1phosphoglycerate kinase 10.082
KLF4Kruppel-like factor 4 (gut)0.079
IL6Rinterleukin 6 receptor0.078
TNFRSF12Atumor necrosis factor receptor superfamily, member 12A0.077
TSPOtranslocator protein (18kDa)0.075
PGAM1phosphoglycerate mutase 1 (brain)0.074
PTPN11protein tyrosine phosphatase, non-receptor type 110.074
LCATlecithin-cholesterol acyltransferase0.071
JUNDjun D proto-oncogene0.071
HBE1hemoglobin, epsilon 10.070
TNIP1TNFAIP3 interacting protein 10.070
PRDX6peroxiredoxin 60.069
APOHapolipoprotein H (beta-2-glycoprotein I)0.069
TPP1tripeptidyl peptidase I0.069
FOXO1forkhead box O10.069
DUSP23dual specificity phosphatase 230.069
PLATplasminogen activator, tissue0.069
KEAP1kelch-like ECH-associated protein 10.067
PRKAG1protein kinase, AMP-activated, gamma 1 non-catalytic subunit0.064
APOA1apolipoprotein A-I0.063
C3complement component 30.060
CREBBPCREB binding protein0.058
CCND2cyclin D20.058
APOC3apolipoprotein C-III0.057
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.055
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.055
PRMT2protein arginine methyltransferase 20.054
FASFas (TNF receptor superfamily, member 6)0.054
HBDhemoglobin, delta0.053
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
gst-6Protein GST-60.017
CELE_T28F3.8Protein T28F3.80.015
gst-13Protein GST-130.013
C53B4.3Protein C53B4.30.012
H43E16.1Protein H43E16.10.011
dsc-4Protein DSC-40.011
unc-112Protein UNC-1120.011
ugt-48Protein UGT-480.010
lbp-7Protein LBP-70.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
Sod2Superoxide dismutase 2 (Mn)0.171
tefutelomere fusion0.109
SodSuperoxide dismutase0.101
kibrakibra ortholog0.071
AldhAldehyde dehydrogenase0.063
dj-1betaCG1349 gene product from transcript CG1349-RA0.063
CG30410CG30410 gene product from transcript CG30410-RB0.061
CG13319CG13319 gene product from transcript CG13319-RA0.052
ash1absent, small, or homeotic discs 10.051
XNPCG4548 gene product from transcript CG4548-RA0.044
PHGPxCG12013 gene product from transcript CG12013-RC0.036
NLazNeural Lazarillo0.035
ThorCG8846 gene product from transcript CG8846-RA0.033
LnkCG17367 gene product from transcript CG17367-RC0.031
Pink1PTEN-induced putative kinase 10.031
CG6543CG6543 gene product from transcript CG6543-RA0.029
GLazGlial Lazarillo0.027
DJ-1alphaCG6646 gene product from transcript CG6646-RA0.025
CG8036CG8036 gene product from transcript CG8036-RB0.020
Mpk2CG5475 gene product from transcript CG5475-RB0.020
Trim9CG31721 gene product from transcript CG31721-RB0.020
CG14715CG14715 gene product from transcript CG14715-RA0.017
Rac1CG2248 gene product from transcript CG2248-RA0.016
Spn27ASerpin 27A0.015
MTF-1Metal response element-binding Transcription Factor-10.014
KhcKinesin heavy chain0.014
rtGEFrho-type guanine exchange factor0.013
fhfrataxin homolog0.013
PvrPDGF- and VEGF-receptor related0.013
TFAMmitochondrial transcription factor A0.013
CG6783CG6783 gene product from transcript CG6783-RC0.012
Mekk1CG7717 gene product from transcript CG7717-RB0.011
CG9425CG9425 gene product from transcript CG9425-RB0.011
CG11858CG11858 gene product from transcript CG11858-RA0.011
Prx5Peroxiredoxin 50.011
IP3K2Inositol 1,4,5-triphosphate kinase 20.011
Lectin-galC1Galactose-specific C-type lectin0.011
Fkbp13CG9847 gene product from transcript CG9847-RC0.011
p38bCG7393 gene product from transcript CG7393-RA0.010
l(3)82FdCG32464 gene product from transcript CG32464-RR0.010
lidlittle imaginal discs0.010
foxoforkhead box, sub-group O0.010
PcmtProtein-L-isoaspartate (D-aspartate) O-methyltransferase0.010
CG13890CG13890 gene product from transcript CG13890-RA0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Alas2aminolevulinate, delta-, synthase 20.434
Hbbhemoglobin, beta0.178
LOC100134871beta globin minor gene0.142
Hba-a2hemoglobin alpha, adult chain 20.079
JunJun oncogene0.059
Hbb-b1hemoglobin, beta adult major chain0.054
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.035
Gadd45agrowth arrest and DNA-damage-inducible, alpha0.035
Egr1early growth response 10.034
Atf3activating transcription factor 30.025
Zfp36zinc finger protein 360.024
Gstp1glutathione S-transferase pi 10.024
Oaz1ornithine decarboxylase antizyme 10.023
Cd48Cd48 molecule0.023
Prdx2peroxiredoxin 20.023
Btg2BTG family, member 20.023
LOC287167globin, alpha0.023
Ptgs2prostaglandin-endoperoxide synthase 20.022
Dusp1dual specificity phosphatase 10.021
Ppp1r15aprotein phosphatase 1, regulatory (inhibitor) subunit 15A0.020
Junbjun B proto-oncogene0.020
Ier3immediate early response 30.019
FosFBJ osteosarcoma oncogene0.019
Rabac1Rab acceptor 1 (prenylated)0.018
S100a10S100 calcium binding protein A100.017
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.017
Smad1SMAD family member 10.017
Mdm2Mdm2 p53 binding protein homolog (mouse)0.016
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.016
Tp53tumor protein p530.016
Klf9Kruppel-like factor 90.016
Hsd17b10hydroxysteroid (17-beta) dehydrogenase 100.016
Hmox1heme oxygenase (decycling) 10.015
Pebp1phosphatidylethanolamine binding protein 10.015
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.015
S100a11S100 calcium binding protein A11 (calizzarin)0.015
Gpx4glutathione peroxidase 40.015
Mafkv-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)0.015
S100a6S100 calcium binding protein A60.014
Nup153nucleoporin 1530.014
Eif4ebp1eukaryotic translation initiation factor 4E binding protein 10.014
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.014
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.014
Ctsl1cathepsin L10.014
Lgals3lectin, galactoside-binding, soluble, 30.014
Tnfrsf12atumor necrosis factor receptor superfamily, member 12a0.013
Psmb3proteasome (prosome, macropain) subunit, beta type 30.013
Il13ra1interleukin 13 receptor, alpha 10.013
Platplasminogen activator, tissue0.013
Txnrd1thioredoxin reductase 10.013
Chchd2coiled-coil-helix-coiled-coil-helix domain containing 20.013
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.012
Atf4activating transcription factor 4 (tax-responsive enhancer element B67)0.012
Srxn1sulfiredoxin 1 homolog (S. cerevisiae)0.012
Prdx1peroxiredoxin 10.012
PVRpoliovirus receptor0.012
Anxa4annexin A40.012
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.012
Gabarapl1GABA(A) receptor-associated protein like 10.012
Ypel5yippee-like 5 (Drosophila)0.012
Jak2Janus kinase 20.012
Klf6Kruppel-like factor 60.012
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.012
Ctdsp1CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 10.012
Mgst2microsomal glutathione S-transferase 20.012
Gja1gap junction protein, alpha 10.012
Cox6a1cytochrome c oxidase, subunit VIa, polypeptide 10.012
Rab11aRAB11a, member RAS oncogene family0.011
Nqo1NAD(P)H dehydrogenase, quinone 10.011
Fkbp4FK506 binding protein 40.011
Tsc22d3TSC22 domain family, member 30.011
Sod1superoxide dismutase 1, soluble0.011
Top2atopoisomerase (DNA) II alpha0.011
Psmb5proteasome (prosome, macropain) subunit, beta type 50.011
Sepp1selenoprotein P, plasma, 10.011
Lgals5lectin, galactose binding, soluble 50.011
Tor1aip2torsin A interacting protein 20.011
Akr1a1aldo-keto reductase family 1, member A1 (aldehyde reductase)0.011
PawrPRKC, apoptosis, WT1, regulator0.011
Idh1isocitrate dehydrogenase 1 (NADP+), soluble0.011
Psmb7proteasome (prosome, macropain) subunit, beta type 70.011
Tjp1tight junction protein 10.011
Psmb4proteasome (prosome, macropain) subunit, beta type 40.011
Spry1sprouty homolog 1, antagonist of FGF signaling (Drosophila)0.011
RT1-EC2RT1 class Ib, locus EC20.011
Pompproteasome maturation protein0.011
Htr5b5-hydroxytryptamine (serotonin) receptor 5B0.011
Ubbubiquitin B0.010
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.010
Cdkn1acyclin-dependent kinase inhibitor 1A0.010
Slc44a2solute carrier family 44, member 20.010
Hdac7histone deacetylase 70.010
Nploc4nuclear protein localization 4 homolog (S. cerevisiae)0.010
F3coagulation factor III (thromboplastin, tissue factor)0.010
Lgals1lectin, galactoside-binding, soluble, 10.010
Icam1intercellular adhesion molecule 10.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism