The network for 'response to virus' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

response to virus

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a virus.

NameDescriptionProbabilityFunc Analog Organism
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.995
DDX58DEAD (Asp-Glu-Ala-Asp) box polypeptide 580.995
IFI44interferon-induced protein 440.995
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.992
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.990
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.990
IFIT3interferon-induced protein with tetratricopeptide repeats 30.983
SP110SP110 nuclear body protein0.977
ACTG1actin, gamma 10.976
BAXBCL2-associated X protein0.966
PMLpromyelocytic leukemia0.963
EIF2AK2eukaryotic translation initiation factor 2-alpha kinase 20.953
IFITM1interferon induced transmembrane protein 1 (9-27)0.945
MX2myxovirus (influenza virus) resistance 2 (mouse)0.942
PLSCR1phospholipid scramblase 10.941
OAS22'-5'-oligoadenylate synthetase 2, 69/71kDa0.939
SP100SP100 nuclear antigen0.934
BCL2L1BCL2-like 10.907
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.882
OASL2'-5'-oligoadenylate synthetase-like0.878
IFI44Linterferon-induced protein 44-like0.853
CAV1caveolin 1, caveolae protein, 22kDa0.844
TRAF3TNF receptor-associated factor 30.844
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.825
BCL2B-cell CLL/lymphoma 20.813
UBCubiquitin C0.813
TRIM22tripartite motif containing 220.811
IFIT2interferon-induced protein with tetratricopeptide repeats 20.808
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.802
PTPN1protein tyrosine phosphatase, non-receptor type 10.801
STAT1signal transducer and activator of transcription 1, 91kDa0.782
IFI16interferon, gamma-inducible protein 160.773
OAS12',5'-oligoadenylate synthetase 1, 40/46kDa0.765
CCR5chemokine (C-C motif) receptor 50.760
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.759
MCL1myeloid cell leukemia sequence 1 (BCL2-related)0.758
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.752
CHUKconserved helix-loop-helix ubiquitous kinase0.751
DICER1dicer 1, ribonuclease type III0.746
TRIM21tripartite motif containing 210.745
HDAC4histone deacetylase 40.744
IFIH1interferon induced with helicase C domain 10.725
HSPB8heat shock 22kDa protein 80.715
MX1myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)0.712
TAL1T-cell acute lymphocytic leukemia 10.710
IRF7interferon regulatory factor 70.695
MAP3K7mitogen-activated protein kinase kinase kinase 70.675
DDX60DEAD (Asp-Glu-Ala-Asp) box polypeptide 600.674
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.668
IFITM3interferon induced transmembrane protein 3 (1-8U)0.667
RUNX1runt-related transcription factor 10.647
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.644
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.633
IL2RBinterleukin 2 receptor, beta0.605
PRKRAprotein kinase, interferon-inducible double stranded RNA dependent activator0.589
IFI35interferon-induced protein 350.575
IFIT1interferon-induced protein with tetratricopeptide repeats 10.565
CCR1chemokine (C-C motif) receptor 10.564
HERC5hect domain and RLD 50.556
CASP8caspase 8, apoptosis-related cysteine peptidase0.529
BIRC3baculoviral IAP repeat containing 30.510
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.493
GAS6growth arrest-specific 60.488
CREBBPCREB binding protein0.486
SUFUsuppressor of fused homolog (Drosophila)0.481
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.478
BCL2L11BCL2-like 11 (apoptosis facilitator)0.477
MAVSmitochondrial antiviral signaling protein0.472
FASFas (TNF receptor superfamily, member 6)0.462
ISG15ISG15 ubiquitin-like modifier0.454
CCL4chemokine (C-C motif) ligand 40.441
CXCL10chemokine (C-X-C motif) ligand 100.435
IL15RAinterleukin 15 receptor, alpha0.434
MAP3K8mitogen-activated protein kinase kinase kinase 80.423
IRF9interferon regulatory factor 90.421
TNFAIP3tumor necrosis factor, alpha-induced protein 30.415
XAF1XIAP associated factor 10.410
CFLARCASP8 and FADD-like apoptosis regulator0.403
NCLnucleolin0.402
IFITM2interferon induced transmembrane protein 2 (1-8D)0.401
RIPK2receptor-interacting serine-threonine kinase 20.381
PILRApaired immunoglobin-like type 2 receptor alpha0.373
MYD88myeloid differentiation primary response gene (88)0.368
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.366
IFIT5interferon-induced protein with tetratricopeptide repeats 50.359
CXCL9chemokine (C-X-C motif) ligand 90.350
TRAF1TNF receptor-associated factor 10.349
SMAD4SMAD family member 40.338
IL23Ainterleukin 23, alpha subunit p190.336
MAP3K14mitogen-activated protein kinase kinase kinase 140.331
TNFRSF9tumor necrosis factor receptor superfamily, member 90.326
HIPK2homeodomain interacting protein kinase 20.326
CD80CD80 molecule0.319
NMIN-myc (and STAT) interactor0.319
TRAF2TNF receptor-associated factor 20.315
JUNjun proto-oncogene0.308
CCL8chemokine (C-C motif) ligand 80.302
ACTBactin, beta0.294
CTLA4cytotoxic T-lymphocyte-associated protein 40.294
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.291
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
T09B4.8Protein T09B4.80.011
dpy-2Protein DPY-20.010
gly-8Protein GLY-80.010
mig-32Protein MIG-320.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mmp9matrix metalloproteinase 90.966
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.884
socs3asuppressor of cytokine signaling 3a0.509
zgc:153997zgc:1539970.435
caspacaspase a0.352
ifnphi1interferon phi 10.350
aplp2amyloid beta (A4) precursor-like protein 20.338
ptgdsprostaglandin D2 synthase0.327
gadd45bbgrowth arrest and DNA-damage-inducible, beta b0.310
mst1rbmacrophage stimulating 1 receptor (c-met-related tyrosine kinase), b0.245
junbjun B proto-oncogene0.242
nfkbiabnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b0.221
junbljun B proto-oncogene, like0.208
stat1asignal transduction and activation of transcription 1a0.202
hif1abhypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) b0.198
bmp7bbone morphogenetic protein 7b0.195
il7rinterleukin 7 receptor0.195
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.193
irf11interferon regulatory factor 110.192
pkzprotein kinase containing Z-DNA binding domains0.192
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.179
desmadesmin a0.174
dag1dystroglycan 10.174
aldh1l1aldehyde dehydrogenase 1 family, member L10.157
fosv-fos FBJ murine osteosarcoma viral oncogene homolog0.157
gadd45bagrowth arrest and DNA-damage-inducible, beta a0.156
atp6v1baATPase, H+ transporting, lysosomal, V1 subunit B, member a0.148
klf2aKruppel-like factor 2a0.145
btg2B-cell translocation gene 20.143
il1binterleukin 1, beta and interleukin 1, beta0.136
gna12guanine nucleotide binding protein (G protein) alpha 120.133
ahcyl1S-adenosylhomocysteine hydrolase-like 10.132
LOC100000332e3 ubiquitin-protein ligase RNF182-like0.112
mxamyxovirus (influenza) resistance A0.112
jak3Janus kinase 3 (a protein tyrosine kinase, leukocyte)0.110
stc1lstanniocalcin 1, like0.108
socs3bsuppressor of cytokine signaling 3b0.104
junjun proto-oncogene0.103
pim1pim-1 oncogene0.100
LOC100331484hypothetical protein LOC1003314840.097
apoebapolipoprotein Eb0.095
sat1aspermidine/spermine N1-acetyltransferase 1a0.093
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.091
cxcr4bchemokine (C-X-C motif), receptor 4b0.091
ippkinositol 1,3,4,5,6-pentakisphosphate 2-kinase0.088
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.085
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.085
rps28ribosomal protein S280.085
styk1serine/threonine/tyrosine kinase 10.084
bcl2l1bcl2-like 10.082
COX1cytochrome c oxidase subunit I0.081
LOC100004946transient receptor potential cation channel subfamily M member 4-like0.079
zgc:162126zgc:1621260.075
mcl1amyeloid cell leukemia sequence 1a0.074
f2rl1.2coagulation factor II (thrombin) receptor-like 1.20.074
casp8caspase 8, apoptosis-related cysteine peptidase0.072
tlr3toll-like receptor 30.071
jak1Janus kinase 10.070
crfa31.2IL-4RA-like protein 20.067
bbs4Bardet-Biedl syndrome 40.066
gadd45aagrowth arrest and DNA-damage-inducible, alpha, a0.066
nos2anitric oxide synthase 2a, inducible0.064
ef1aelongation factor 1-alpha0.063
rykreceptor-like tyrosine kinase0.060
tlr2toll-like receptor 20.060
pnrc2proline-rich nuclear receptor coactivator 20.060
baxabcl2-associated X protein, a0.058
cd247lCD247 antigen like0.058
cyt1type I cytokeratin, enveloping layer0.057
tlr22toll-like receptor 220.056
ddx42DEAD (Asp-Glu-Ala-Asp) box polypeptide 420.056
pth1aparathyroid hormone 1a0.056
abcb3l1ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 10.056
bbc3BCL2 binding component 30.055
col5a3bcollagen type V alpha-3b0.055
atf3activating transcription factor 30.054
irf6interferon regulatory factor 60.053
pdgfaaplatelet-derived growth factor alpha a0.053
nap1l1nucleosome assembly protein 1, like 10.053
col5a2lcollagen, type V, alpha 2-like0.052
psmd6proteasome (prosome, macropain) 26S subunit, non-ATPase, 60.051
s100a10bS100 calcium binding protein A10b0.051
hectd1HECT domain containing 10.050
zgc:56376zgc:563760.050
rpl36aribosomal protein L36A0.049
il12bbinterleukin 12B, b0.049
slco2b1solute carrier organic anion transporter family, member 2B10.048
actc1bactin, alpha, cardiac muscle 1b0.048
adipor1aadiponectin receptor 1a0.047
ddr2bdiscoidin domain receptor family, member 2b0.047
mcm4MCM4 minichromosome maintenance deficient 4, mitotin (S. cerevisiae)0.046
ranbp1RAN binding protein 10.046
epas1bendothelial PAS domain protein 1b0.045
zgc:66382zgc:663820.045
tuba7ltubulin, alpha 7 like0.044
relv-rel reticuloendotheliosis viral oncogene homolog0.043
tlr9toll-like receptor 90.042
tfe3atranscription factor binding to IGHM enhancer 3a0.042
cd8aCD8 antigen, alpha polypeptide0.042
dnm2dynamin 20.041
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
RelRelish0.999
TlToll0.928
Tak1TGF-beta activated kinase 10.889
AttAAttacin-A0.888
DreddDeath related ced-3/Nedd2-like protein0.876
bskbasket0.873
BG4CG12297 gene product from transcript CG12297-RA0.690
ird5immune response deficient 50.566
18w18 wheeler0.496
imdimmune deficiency0.476
keykenny0.465
Dcr-2Dicer-20.380
PGRP-LCPeptidoglycan recognition protein LC0.339
PGRP-SDCG7496 gene product from transcript CG7496-RA0.322
CatCatalase0.280
Sema-1bCG6446 gene product from transcript CG6446-RA0.278
srasarah0.266
Atg9Autophagy-specific gene 90.250
PGRP-SAPeptidoglycan recognition protein SA0.246
mubmushroom-body expressed0.243
Hsp27Heat shock protein 270.242
whdwithered0.233
r2d2CG7138 gene product from transcript CG7138-RB0.223
krzkurtz0.222
spzspatzle0.217
Lis-1Lissencephaly-10.197
T-cp1Tcp1-like0.189
fwdfour wheel drive0.179
EgfrEpidermal growth factor receptor0.173
AGO2Argonaute 20.151
RASSF8CG5053 gene product from transcript CG5053-RA0.136
Cyp316a1CG8540 gene product from transcript CG8540-RA0.131
Atg18Autophagy-specific gene 180.130
Drp1Dynamin related protein 10.130
PvrPDGF- and VEGF-receptor related0.129
osoutstretched0.122
Spn1Serine protease inhibitor 10.119
Mpk2CG5475 gene product from transcript CG5475-RB0.117
bazbazooka0.115
qkr58E-3quaking related 58E-30.114
HsfHeat shock factor0.112
unc79CG5237 gene product from transcript CG5237-RB0.109
exdextradenticle0.101
AttCAttacin-C0.097
Rho1CG8416 gene product from transcript CG8416-RB0.094
Myd88CG2078 gene product from transcript CG2078-RA0.093
spasspastin0.092
PGRP-SC1aCG14746 gene product from transcript CG14746-RA0.090
nudCCG9710 gene product from transcript CG9710-RA0.085
CG16718CG16718 gene product from transcript CG16718-RA0.085
CG7033CG7033 gene product from transcript CG7033-RC0.084
MtkMetchnikowin0.083
PGRP-LFPeptidoglycan recognition protein LF0.078
PGRP-SC1bCG8577 gene product from transcript CG8577-RA0.078
PliPellino0.077
p38bCG7393 gene product from transcript CG7393-RA0.076
pirkpoor Imd response upon knock-in0.076
upd2unpaired 20.072
scnyscrawny0.069
LamCLamin C0.069
ird1immune response deficient 10.068
DptBDiptericin B0.067
Atg13Autophagy-specific gene 130.063
CG18594CG18594 gene product from transcript CG18594-RA0.061
Mekk1CG7717 gene product from transcript CG7717-RB0.059
CG5844CG5844 gene product from transcript CG5844-RA0.059
ced-6CG11804 gene product from transcript CG11804-RC0.057
tsrtwinstar0.057
ChcClathrin heavy chain0.056
lin19lin-19-like0.056
CG15917CG15917 gene product from transcript CG15917-RA0.054
Sir2CG5216 gene product from transcript CG5216-RA0.054
CG17107CG17107 gene product from transcript CG17107-RA0.054
SPESpatzle-Processing Enzyme0.053
CG8155CG8155 gene product from transcript CG8155-RA0.052
TM9SF4CG7364 gene product from transcript CG7364-RA0.051
fonfondue0.050
Atg1Autophagy-specific gene 10.050
PGRP-LBPeptidoglycan recognition protein LB0.049
Pp1alpha-96AProtein phosphatase 1alpha at 96A0.049
CG9184CG9184 gene product from transcript CG9184-RB0.047
pashapartner of drosha0.047
eIF-5ACG3186 gene product from transcript CG3186-RA0.046
CG4673CG4673 gene product from transcript CG4673-RB0.045
Or22aOdorant receptor 22a0.045
knknot0.044
Obp19aOdorant-binding protein 19a0.043
sqhspaghetti squash0.043
RagACG11968 gene product from transcript CG11968-RA0.043
CG42369CG42369 gene product from transcript CG42369-RA0.042
Akap200A kinase anchor protein 2000.042
CG33307CG33307 gene product from transcript CG33307-RA0.041
Adf1Adh transcription factor 10.041
DuoxDual oxidase0.041
Nrx-IVNeurexin IV0.040
Oatp33EbOrganic anion transporting polypeptide 33Eb0.040
grassGram-positive Specific Serine protease0.040
Vap-33-1CG5014 gene product from transcript CG5014-RB0.038
Traf4TNF-receptor-associated factor 40.038
CG3632CG3632 gene product from transcript CG3632-RH0.035
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Ifit3interferon-induced protein with tetratricopeptide repeats 30.825
Oas1a2'-5' oligoadenylate synthetase 1A0.704
Cxcl10chemokine (C-X-C motif) ligand 100.668
Ccl2chemokine (C-C motif) ligand 20.570
Ccl5chemokine (C-C motif) ligand 50.429
RT1-EC2RT1 class Ib, locus EC20.346
Usp18ubiquitin specific peptidase 180.323
Il1binterleukin 1 beta0.282
RT1-S3RT1 class Ib, locus S30.273
Csf2rbcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.225
Cd86CD86 molecule0.203
Psmc2proteasome (prosome, macropain) 26S subunit, ATPase 20.178
Irf7interferon regulatory factor 70.163
LOC100364500RT1 class I, locus CE11-like0.160
Tnftumor necrosis factor (TNF superfamily, member 2)0.132
Mmp12matrix metallopeptidase 120.120
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.111
Il2rbinterleukin 2 receptor, beta0.106
Nkg7natural killer cell group 7 sequence0.105
Ccl4chemokine (C-C motif) ligand 40.103
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.093
Rarres2retinoic acid receptor responder (tazarotene induced) 20.087
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.085
Mx1myxovirus (influenza virus) resistance 10.084
Sellselectin L0.083
Cxcl9chemokine (C-X-C motif) ligand 90.082
Reg3bregenerating islet-derived 3 beta0.079
Isg15ISG15 ubiquitin-like modifier0.076
Il6interleukin 60.073
Cct2chaperonin containing TCP1, subunit 2 (beta)0.070
Klrd1killer cell lectin-like receptor, subfamily D, member 10.068
Lgals9lectin, galactoside-binding, soluble, 90.064
Clec9aC-type lectin domain family 9, member a0.060
LOC100363783rCG53773-like0.056
Cxcl2chemokine (C-X-C motif) ligand 20.047
Fcgr3aFc fragment of IgG, low affinity IIIa, receptor0.046
Aif1allograft inflammatory factor 10.046
Ifitm3interferon induced transmembrane protein 30.046
Slfn3schlafen 30.043
Parp9poly (ADP-ribose) polymerase family, member 90.040
Oasl2'-5'-oligoadenylate synthetase-like0.039
Tap1transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)0.039
Apol3apolipoprotein L, 30.038
Cd14CD14 molecule0.038
Arhgap4Rho GTPase activating protein 40.037
Ubdubiquitin D0.036
Hckhemopoietic cell kinase0.035
Lgals3bplectin, galactoside-binding, soluble, 3 binding protein0.035
Cybbcytochrome b-245, beta polypeptide0.035
Il1ainterleukin 1 alpha0.034
Olr1oxidized low density lipoprotein (lectin-like) receptor 10.034
Plaurplasminogen activator, urokinase receptor0.033
Lgals5lectin, galactose binding, soluble 50.032
Gbp2guanylate binding protein 20.032
Cd8bCD8b molecule0.032
Rtp4receptor (chemosensory) transporter protein 40.032
Ccl3chemokine (C-C motif) ligand 30.031
Psmc1proteasome (prosome, macropain) 26S subunit, ATPase, 10.030
RT1-N3RT1 class Ib, locus N30.029
Dnase1l3deoxyribonuclease 1-like 30.029
Hcls1hematopoietic cell specific Lyn substrate 10.027
TcrbT-cell receptor beta chain0.027
Tlr4toll-like receptor 40.027
Hmha1histocompatibility (minor) HA-10.027
Gzmbgranzyme B0.026
Cd2Cd2 molecule0.025
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.025
RT1-CE5RT1 class I, locus CE50.025
Socs3suppressor of cytokine signaling 30.024
Cd38CD38 molecule0.024
Igsf6immunoglobulin superfamily, member 60.024
Zbp1Z-DNA binding protein 10.023
Neurl3neuralized homolog 3 (Drosophila)0.023
Rgs1regulator of G-protein signaling 10.023
Ceacam10carcinoembryonic antigen-related cell adhesion molecule 100.023
Sirpasignal-regulatory protein alpha0.023
Map3k8mitogen-activated protein kinase kinase kinase 80.022
Icam1intercellular adhesion molecule 10.022
Gzmkgranzyme K0.022
Rab32RAB32, member RAS oncogene family0.022
Cd247Cd247 molecule0.020
Kmokynurenine 3-monooxygenase (kynurenine 3-hydroxylase)0.020
Il2rginterleukin 2 receptor, gamma0.020
Cct3chaperonin containing Tcp1, subunit 3 (gamma)0.020
Itgamintegrin, alpha M0.020
Shisa5shisa homolog 5 (Xenopus laevis)0.020
Parp14poly (ADP-ribose) polymerase family, member 140.019
Tcf21transcription factor 210.019
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.019
P2ry14purinergic receptor P2Y, G-protein coupled, 140.019
Pla2g4aphospholipase A2, group IVA (cytosolic, calcium-dependent)0.019
F2rl2coagulation factor II (thrombin) receptor-like 20.019
Pthparathyroid hormone0.019
RT1-Db1RT1 class II, locus Db10.019
Epha2Eph receptor A20.019
Ccr5chemokine (C-C motif) receptor 50.019
Ergic3ERGIC and golgi 30.018
Ncr1natural cytotoxicity triggering receptor 10.018
LOC100364854similar to RIKEN cDNA A430107P09 gene-like0.018
Bin2bridging integrator 20.017
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism