The network for 'glutamine family amino acid metabolic process' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

glutamine family amino acid metabolic process

The chemical reactions and pathways involving amino acids of the glutamine family, comprising arginine, glutamate, glutamine and proline.

Homo sapiens
NameDescriptionProbabilityFunc Analog Organism
GGT1gamma-glutamyltransferase 10.991
GGTLC1gamma-glutamyltransferase light chain 10.967
NOSTRINnitric oxide synthase trafficker0.887
GCLCglutamate-cysteine ligase, catalytic subunit0.665
DNAJA3DnaJ (Hsp40) homolog, subfamily A, member 30.624
GGT2gamma-glutamyltransferase 20.468
VAC14Vac14 homolog (S. cerevisiae)0.462
EPT1ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)0.350
GCLMglutamate-cysteine ligase, modifier subunit0.327
AARSalanyl-tRNA synthetase0.281
MAP2K5mitogen-activated protein kinase kinase 50.277
AIFM1apoptosis-inducing factor, mitochondrion-associated, 10.257
APOOapolipoprotein O0.221
GCDHglutaryl-CoA dehydrogenase0.203
TOM1L1target of myb1 (chicken)-like 10.181
GARTphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase0.132
RCN3reticulocalbin 3, EF-hand calcium binding domain0.130
DLG2discs, large homolog 2 (Drosophila)0.129
PSAT1phosphoserine aminotransferase 10.129
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.101
GLUD2glutamate dehydrogenase 20.087
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.087
PCK2phosphoenolpyruvate carboxykinase 2 (mitochondrial)0.079
VARSvalyl-tRNA synthetase0.069
TMEM97transmembrane protein 970.068
SLC25A15solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 150.065
HIPK2homeodomain interacting protein kinase 20.064
CALCAcalcitonin-related polypeptide alpha0.063
NOS1APnitric oxide synthase 1 (neuronal) adaptor protein0.054
EIF4EBP1eukaryotic translation initiation factor 4E binding protein 10.053
PDHA1pyruvate dehydrogenase (lipoamide) alpha 10.050
GLUD1glutamate dehydrogenase 10.048
FHfumarate hydratase0.047
ATIC5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.046
SHMT2serine hydroxymethyltransferase 2 (mitochondrial)0.044
OSBPL8oxysterol binding protein-like 80.041
TRAP1TNF receptor-associated protein 10.040
PYCR1pyrroline-5-carboxylate reductase 10.038
GFERgrowth factor, augmenter of liver regeneration0.035
SORDsorbitol dehydrogenase0.032
KIF5Bkinesin family member 5B0.029
GOT1glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)0.028
FXNfrataxin0.026
ACLYATP citrate lyase0.026
MACF1microtubule-actin crosslinking factor 10.025
AHCYadenosylhomocysteinase0.025
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.025
RABEPKRab9 effector protein with kelch motifs0.024
DLG1discs, large homolog 1 (Drosophila)0.022
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 20.022
VDAC1voltage-dependent anion channel 10.022
GOT2glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)0.021
BZW2basic leucine zipper and W2 domains 20.021
PTDSS1phosphatidylserine synthase 10.021
CALM1calmodulin 1 (phosphorylase kinase, delta)0.021
MIPEPmitochondrial intermediate peptidase0.021
MAP3K1mitogen-activated protein kinase kinase kinase 10.020
GPT2glutamic pyruvate transaminase (alanine aminotransferase) 20.020
PCCBpropionyl CoA carboxylase, beta polypeptide0.019
PFASphosphoribosylformylglycinamidine synthase0.019
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.019
DSTdystonin0.018
GCATglycine C-acetyltransferase0.017
GIGYF2GRB10 interacting GYF protein 20.017
SLC16A1solute carrier family 16, member 1 (monocarboxylic acid transporter 1)0.017
FBXO30F-box protein 300.017
MCCC1methylcrotonoyl-CoA carboxylase 1 (alpha)0.016
CDK17cyclin-dependent kinase 170.016
WDR12WD repeat domain 120.016
ME1malic enzyme 1, NADP(+)-dependent, cytosolic0.016
SLC19A1solute carrier family 19 (folate transporter), member 10.016
PRPS1phosphoribosyl pyrophosphate synthetase 10.016
ZBTB4zinc finger and BTB domain containing 40.016
TTLL12tubulin tyrosine ligase-like family, member 120.015
TCTN3tectonic family member 30.015
SDHAsuccinate dehydrogenase complex, subunit A, flavoprotein (Fp)0.015
IDEinsulin-degrading enzyme0.015
NUP93nucleoporin 93kDa0.015
OGFOD12-oxoglutarate and iron-dependent oxygenase domain containing 10.015
POP1processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)0.014
ZFP106zinc finger protein 106 homolog (mouse)0.014
IARSisoleucyl-tRNA synthetase0.014
GCN1L1GCN1 general control of amino-acid synthesis 1-like 1 (yeast)0.014
CBScystathionine-beta-synthase0.014
PEBP1phosphatidylethanolamine binding protein 10.013
BTRCbeta-transducin repeat containing0.013
SCRIBscribbled homolog (Drosophila)0.012
SLC7A1solute carrier family 7 (cationic amino acid transporter, y+ system), member 10.012
RUNX1runt-related transcription factor 10.012
SIRT3sirtuin 30.012
PTPLAD1protein tyrosine phosphatase-like A domain containing 10.012
HADHhydroxyacyl-CoA dehydrogenase0.012
MAP3K3mitogen-activated protein kinase kinase kinase 30.012
NAA15N(alpha)-acetyltransferase 15, NatA auxiliary subunit0.012
COQ9coenzyme Q9 homolog (S. cerevisiae)0.011
GHITMgrowth hormone inducible transmembrane protein0.011
GSRglutathione reductase0.011
ARG1arginase, liver0.011
DHODHdihydroorotate dehydrogenase0.011
NRIP1nuclear receptor interacting protein 10.011
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PgmPhosphogluconate mutase0.023
ArgkArginine kinase0.020
IdhIsocitrate dehydrogenase0.017
AdhAlcohol dehydrogenase0.014
OrctOrganic cation transporter0.014
Hex-CHexokinase C0.013
CG15478CG15478 gene product from transcript CG15478-RA0.011
GdhGlutamate dehydrogenase0.011
CG3597CG3597 gene product from transcript CG3597-RA0.011
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lepleptin0.885
Nos1nitric oxide synthase 1, neuronal0.858
Leprleptin receptor0.731
Rxraretinoid X receptor alpha0.673
Cav1caveolin 1, caveolae protein0.470
Ppargperoxisome proliferator activated receptor gamma0.423
Nos3nitric oxide synthase 3, endothelial cell0.353
Esr1estrogen receptor 1 (alpha)0.300
Npc1Niemann Pick type C10.299
Atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.252
Mmp9matrix metallopeptidase 90.242
Apoeapolipoprotein E0.215
Gabrdgamma-aminobutyric acid (GABA) A receptor, subunit delta0.214
Nos2nitric oxide synthase 2, inducible0.164
Insrinsulin receptor0.144
GnasGNAS (guanine nucleotide binding protein, alpha stimulating) complex locus0.104
Ptgs2prostaglandin-endoperoxide synthase 20.102
Nr1i2nuclear receptor subfamily 1, group I, member 20.097
Col1a1collagen, type I, alpha 10.081
Esr2estrogen receptor 2 (beta)0.076
Echs1enoyl Coenzyme A hydratase, short chain, 1, mitochondrial0.074
Srebf2sterol regulatory element binding factor 20.065
Gnrh1gonadotropin releasing hormone 10.065
Dlg4discs, large homolog 4 (Drosophila)0.063
Scd1stearoyl-Coenzyme A desaturase 10.062
Immtinner membrane protein, mitochondrial0.061
Ppargc1aperoxisome proliferative activated receptor, gamma, coactivator 1 alpha0.057
Ptenphosphatase and tensin homolog0.057
Ghrgrowth hormone receptor0.054
Ptpn11protein tyrosine phosphatase, non-receptor type 110.049
Vegfavascular endothelial growth factor A0.049
Pck1phosphoenolpyruvate carboxykinase 1, cytosolic0.048
Vdrvitamin D receptor0.047
Ldlrlow density lipoprotein receptor0.046
Smc1astructural maintenance of chromosomes 1A0.046
Prlrprolactin receptor0.045
Aldh18a1aldehyde dehydrogenase 18 family, member A10.045
Nr5a2nuclear receptor subfamily 5, group A, member 20.043
Itgb1integrin beta 1 (fibronectin receptor beta)0.041
Agtangiotensinogen (serpin peptidase inhibitor, clade A, member 8)0.041
Grm1glutamate receptor, metabotropic 10.040
Sik3SIK family kinase 30.038
Hnf4ahepatic nuclear factor 4, alpha0.035
Shmt2serine hydroxymethyltransferase 2 (mitochondrial)0.035
Nr1h4nuclear receptor subfamily 1, group H, member 40.035
Nr0b2nuclear receptor subfamily 0, group B, member 20.030
Plgplasminogen0.030
Slc12a1solute carrier family 12, member 10.029
Smc3structural maintenace of chromosomes 30.028
Igf1insulin-like growth factor 10.028
Masp2mannan-binding lectin serine peptidase 20.028
Tgfb1transforming growth factor, beta 10.027
Crim1cysteine rich transmembrane BMP regulator 1 (chordin like)0.026
Gpr12G-protein coupled receptor 120.026
Lifleukemia inhibitory factor0.026
Nr3c1nuclear receptor subfamily 3, group C, member 10.025
Csf1colony stimulating factor 1 (macrophage)0.025
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)0.025
CebpbCCAAT/enhancer binding protein (C/EBP), beta0.025
Adra1badrenergic receptor, alpha 1b0.025
Gata6GATA binding protein 60.024
Cdkn1bcyclin-dependent kinase inhibitor 1B0.024
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.024
Grin2aglutamate receptor, ionotropic, NMDA2A (epsilon 1)0.024
Mdh1malate dehydrogenase 1, NAD (soluble)0.023
Gldcglycine decarboxylase0.023
Cyp2d26cytochrome P450, family 2, subfamily d, polypeptide 260.023
Aldobaldolase B, fructose-bisphosphate0.022
Cyp2b10cytochrome P450, family 2, subfamily b, polypeptide 100.022
Adipoqadiponectin, C1Q and collagen domain containing0.022
C77614EST C776140.022
Iydiodotyrosine deiodinase0.022
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.022
Acadsacyl-Coenzyme A dehydrogenase, short chain0.022
Hrhairless0.022
Thrathyroid hormone receptor alpha0.021
Nfe2l2nuclear factor, erythroid derived 2, like 20.021
Gja1gap junction protein, alpha 10.021
Asgr2asialoglycoprotein receptor 20.021
Arandrogen receptor0.020
Hgdhomogentisate 1, 2-dioxygenase0.020
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.020
Cyb5cytochrome b-50.020
Pipoxpipecolic acid oxidase0.020
Sardhsarcosine dehydrogenase0.019
Hsd17b11hydroxysteroid (17-beta) dehydrogenase 110.019
Got1glutamate oxaloacetate transaminase 1, soluble0.019
Pcxpyruvate carboxylase0.019
Hpd4-hydroxyphenylpyruvic acid dioxygenase0.019
Plin1perilipin 10.019
Gabrb1gamma-aminobutyric acid (GABA) A receptor, subunit beta 10.019
Rxrgretinoid X receptor gamma0.019
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.019
Npy2rneuropeptide Y receptor Y20.019
Tlr4toll-like receptor 40.019
Cyp3a25cytochrome P450, family 3, subfamily a, polypeptide 250.018
Notch2Notch gene homolog 2 (Drosophila)0.018
Abcb1aATP-binding cassette, sub-family B (MDR/TAP), member 1A0.018
Spp1secreted phosphoprotein 10.018
Ahraryl-hydrocarbon receptor0.018
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Dnm1ldynamin 1-like0.428
Pahphenylalanine hydroxylase0.091
Hspa9heat shock protein 90.066
Atp1b1ATPase, Na+/K+ transporting, beta 1 polypeptide0.056
Gtpbp4GTP binding protein 40.054
Tle4transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)0.044
Ces1ccarboxylesterase 1C0.043
Adarb2adenosine deaminase, RNA-specific, B20.042
Sardhsarcosine dehydrogenase0.041
Ndrg2N-myc downstream regulated gene 20.039
LOC293989cytochrome P450-like0.038
Nr1i2nuclear receptor subfamily 1, group I, member 20.036
Cyp4a3cytochrome P450, family 4, subfamily a, polypeptide 30.034
Rps6kb1ribosomal protein S6 kinase, polypeptide 10.032
Gnmtglycine N-methyltransferase0.032
Dpysdihydropyrimidinase0.030
Gad2glutamate decarboxylase 20.030
Got2glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2)0.029
Hnf4ahepatocyte nuclear factor 4, alpha0.027
Cyp2c22cytochrome P450, family 2, subfamily c, polypeptide 220.025
LOC299282Serine protease inhibitor0.024
Slc2a4solute carrier family 2 (facilitated glucose transporter), member 40.023
Tfrctransferrin receptor0.022
Gcgroup specific component0.020
Pck1phosphoenolpyruvate carboxykinase 1 (soluble)0.020
Purbpurine rich element binding protein B0.019
TufmTu translation elongation factor, mitochondrial0.019
Ipo4importin 40.019
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.019
Cabc1chaperone, ABC1 activity of bc1 complex homolog (S. pombe)0.019
Glud1glutamate dehydrogenase 10.019
Chrnb2cholinergic receptor, nicotinic, beta 2 (neuronal)0.018
Slit1slit homolog 1 (Drosophila)0.017
Pgm1phosphoglucomutase 10.017
Mtmr7myotubularin related protein 70.017
Rc3h2ring finger and CCCH-type zinc finger domains 20.017
Cdx1caudal type homeo box 10.017
Il1r1interleukin 1 receptor, type I0.017
Sdsserine dehydratase0.017
Lonp2lon peptidase 2, peroxisomal0.016
Plaaphospholipase A2, activating protein0.016
Akap5A kinase (PRKA) anchor protein 50.016
Slc22a1solute carrier family 22 (organic cation transporter), member 10.016
Abat4-aminobutyrate aminotransferase0.016
Car5acarbonic anhydrase 5a, mitochondrial0.016
Pgk1phosphoglycerate kinase 10.016
Ipo5importin 50.015
Abp10annexin V-binding protein ABP-100.015
Nolc1nucleolar and coiled-body phosphoprotein 10.015
Agxt2alanine-glyoxylate aminotransferase 20.015
Nipsnap1nipsnap homolog 1 (C. elegans)0.015
Hao2hydroxyacid oxidase 2 (long chain)0.015
Hnrpdheterogeneous nuclear ribonucleoprotein D0.015
Ndufa10l1NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 10-like 10.014
Igfalsinsulin-like growth factor binding protein, acid labile subunit0.014
Creb1cAMP responsive element binding protein 10.014
Arih1ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)0.014
Fbp1fructose-1,6-bisphosphatase 10.014
Sox17SRY (sex determining region Y)-box 170.014
Vdac1voltage-dependent anion channel 10.014
FggyFGGY carbohydrate kinase domain containing0.014
Fgd4FYVE, RhoGEF and PH domain containing 40.013
Lamb2laminin, beta 20.013
RGD1564327similar to integrin alpha 80.013
Slco2a1solute carrier organic anion transporter family, member 2a10.013
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.013
Amhanti-Mullerian hormone0.013
Ugt2bUDP glycosyltransferase 2 family, polypeptide B0.013
Idh2isocitrate dehydrogenase 2 (NADP+), mitochondrial0.013
Htr2c5-hydroxytryptamine (serotonin) receptor 2C0.013
Ass1argininosuccinate synthetase 10.013
Kif12kinesin family member 120.013
Copz2coatomer protein complex, subunit zeta 20.013
Apoc4apolipoprotein C-IV0.013
AuhAU RNA binding protein/enoyl-coenzyme A hydratase0.013
Sult2a2sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 20.013
Pecam1platelet/endothelial cell adhesion molecule 10.012
Smosmoothened homolog (Drosophila)0.012
Khkketohexokinase0.012
Orm1orosomucoid 10.012
Lman1lectin, mannose-binding, 10.012
Ppa2pyrophosphatase (inorganic) 20.012
Fahfumarylacetoacetate hydrolase0.012
RGD1563106similar to novel protein0.012
Cpt1bcarnitine palmitoyltransferase 1b, muscle0.012
Neu2sialidase 2 (cytosolic sialidase)0.012
Serpina3kserine (or cysteine) peptidase inhibitor, clade A, member 3K0.012
Mcf2lMCF.2 cell line derived transforming sequence-like0.012
RGD1563319similar to RIKEN cDNA 6330512M04 gene0.012
Aldh1a1aldehyde dehydrogenase 1 family, member A10.011
Adra1badrenergic, alpha-1B-, receptor0.011
Dlstdihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)0.011
Gstt2glutathione S-transferase, theta 20.011
Aldh2aldehyde dehydrogenase 2 family (mitochondrial)0.011
Cmklr1chemokine-like receptor 10.011
Fat3FAT tumor suppressor homolog 3 (Drosophila)0.011
Akt3v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)0.011
Dync2h1dynein cytoplasmic 2 heavy chain 10.011
Tubtubby homolog (mouse)0.011
Gartphosphoribosylglycinamide formyltransferase0.011
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
ASP3-4Asp3-4p0.937
ARG3Arg3p0.924
ARG5,6Arg5,6p0.887
YOR302Whypothetical protein0.826
CPA2Cpa2p0.801
ARG81Arg81p0.656
ASP3-3Asp3-3p0.428
ARG1Arg1p0.413
ASP3-2Asp3-2p0.396
ARO1Aro1p0.365
ARG8Arg8p0.326
ARG7Arg7p0.318
ASP3-1Asp3-1p0.314
LEU4Leu4p0.230
PUT1Put1p0.218
NCE103Nce103p0.207
CAR1Car1p0.195
GGC1Ggc1p0.184
CAR2Car2p0.171
GDH1Gdh1p0.166
ODC2Odc2p0.145
RBG1Rbg1p0.123
UGA3Uga3p0.110
ILV1Ilv1p0.105
GFA1Gfa1p0.103
ARG80Arg80p0.098
ILV5Ilv5p0.095
SMM1Smm1p0.093
PUT2Put2p0.091
GUS1Gus1p0.089
LEU9Leu9p0.088
DDR48Ddr48p0.083
ARG4Arg4p0.081
MAE1Mae1p0.078
PCL5Pcl5p0.075
ATR1Atr1p0.074
SPE3Spe3p0.074
FRS1Frs1p0.067
AAC3Aac3p0.065
CPA1Cpa1p0.065
BDH2Bdh2p0.064
ORT1Ort1p0.064
ILV3Ilv3p0.063
CCT8Cct8p0.062
BOP3Bop3p0.059
TRR1Trr1p0.058
LYS1Lys1p0.055
ARG2Arg2p0.054
CAM1Cam1p0.052
FAA2Faa2p0.052
YOL014Whypothetical protein0.052
DUR1,2Dur1,2p0.049
HTS1Hts1p0.049
ARO3Aro3p0.049
IDP3Idp3p0.048
MIS1Mis1p0.047
YPT53Ypt53p0.047
ALD2Ald2p0.046
FMO1Fmo1p0.046
CPS1Cps1p0.045
CBR1Cbr1p0.044
PRS2Prs2p0.044
COT1Cot1p0.044
FUI1Fui1p0.043
CDC48Cdc48p0.043
ILV6Ilv6p0.043
REE1Ree1p0.042
YLR264C-Ahypothetical protein0.041
DLD3Dld3p0.041
URA1Ura1p0.040
HPT1Hpt1p0.038
YLR162Whypothetical protein0.038
BUD17Bud17p0.038
HXT3Hxt3p0.038
PSA1Psa1p0.038
AUA1Aua1p0.037
CIT2Cit2p0.037
GRE2Gre2p0.037
ALD5Ald5p0.036
URA8Ura8p0.036
SHM1Shm1p0.035
TIP1Tip1p0.035
SRD1Srd1p0.035
NPA3Npa3p0.034
MCX1Mcx1p0.033
MER1Mer1p0.033
YHM2Yhm2p0.033
URA3Ura3p0.033
FAA4Faa4p0.033
RPA135Rpa135p0.032
YBR085C-Ahypothetical protein0.032
ATO3Ato3p0.032
IDP1Idp1p0.032
HIS5His5p0.032
TKL2Tkl2p0.031
YGP1Ygp1p0.030
YIR035Chypothetical protein0.030
ADH5Adh5p0.030
NAR1Nar1p0.030
YOL038C-Ahypothetical protein0.029