The network for 'mitotic cell cycle checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mitotic cell cycle checkpoint

A cell cycle checkpoint that ensures accurate chromosome replication and segregation by preventing progression through a mitotic cell cycle until conditions are suitable for the cell to proceed to the next stage.

NameDescriptionProbabilityFunc Analog Organism
TP53tumor protein p531.000
RB1retinoblastoma 11.000
MDM2Mdm2 p53 binding protein homolog (mouse)1.000
BRCA1breast cancer 1, early onset0.998
RAD51RAD51 homolog (RecA homolog, E. coli) (S. cerevisiae)0.992
MDC1mediator of DNA-damage checkpoint 10.989
CDK2cyclin-dependent kinase 20.981
COPS5COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)0.981
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide0.932
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma0.916
PLK1polo-like kinase 10.886
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.847
BRCA2breast cancer 2, early onset0.798
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.761
H2AFXH2A histone family, member X0.756
E2F1E2F transcription factor 10.751
RBL1retinoblastoma-like 1 (p107)0.749
RAD50RAD50 homolog (S. cerevisiae)0.717
CDC25Acell division cycle 25 homolog A (S. pombe)0.717
COPS4COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis)0.688
BUB1budding uninhibited by benzimidazoles 1 homolog (yeast)0.676
PRKDCprotein kinase, DNA-activated, catalytic polypeptide0.670
BCL2B-cell CLL/lymphoma 20.616
CHEK1CHK1 checkpoint homolog (S. pombe)0.612
CALM1calmodulin 1 (phosphorylase kinase, delta)0.611
SKP2S-phase kinase-associated protein 2 (p45)0.605
HDAC1histone deacetylase 10.601
CUL1cullin 10.593
BCL2L1BCL2-like 10.590
XIAPX-linked inhibitor of apoptosis0.573
CLSPNclaspin0.568
CCNE1cyclin E10.567
CUL2cullin 20.544
EME1essential meiotic endonuclease 1 homolog 1 (S. pombe)0.506
CCNA2cyclin A20.503
CUL4Acullin 4A0.500
CDC45cell division cycle 45 homolog (S. cerevisiae)0.480
MCM7minichromosome maintenance complex component 70.469
MSH6mutS homolog 6 (E. coli)0.468
CCNB1cyclin B10.464
BUB1Bbudding uninhibited by benzimidazoles 1 homolog beta (yeast)0.464
TOPBP1topoisomerase (DNA) II binding protein 10.458
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.454
CHEK2CHK2 checkpoint homolog (S. pombe)0.447
PARP1poly (ADP-ribose) polymerase 10.441
PPP2R1Bprotein phosphatase 2, regulatory subunit A, beta0.437
COPS3COP9 constitutive photomorphogenic homolog subunit 3 (Arabidopsis)0.435
RFWD2ring finger and WD repeat domain 20.424
CASP8caspase 8, apoptosis-related cysteine peptidase0.406
UBA1ubiquitin-like modifier activating enzyme 10.387
DDB1damage-specific DNA binding protein 1, 127kDa0.368
RAD1RAD1 homolog (S. pombe)0.363
CCND1cyclin D10.363
ATMataxia telangiectasia mutated0.361
RBBP8retinoblastoma binding protein 80.360
CDC27cell division cycle 27 homolog (S. cerevisiae)0.360
CCND3cyclin D30.358
CDK8cyclin-dependent kinase 80.350
MED1mediator complex subunit 10.346
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme0.334
ZWINTZW10 interactor0.325
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.317
UHRF2ubiquitin-like with PHD and ring finger domains 20.304
JUNjun proto-oncogene0.292
WRNWerner syndrome, RecQ helicase-like0.289
MCM2minichromosome maintenance complex component 20.289
RBL2retinoblastoma-like 2 (p130)0.286
CSNK2Bcasein kinase 2, beta polypeptide0.285
PKM2pyruvate kinase, muscle0.279
CDC25Ccell division cycle 25 homolog C (S. pombe)0.271
CDK6cyclin-dependent kinase 60.270
BUB3budding uninhibited by benzimidazoles 3 homolog (yeast)0.267
APAF1apoptotic peptidase activating factor 10.266
FADDFas (TNFRSF6)-associated via death domain0.264
FASFas (TNF receptor superfamily, member 6)0.256
TRIP13thyroid hormone receptor interactor 130.250
DDB2damage-specific DNA binding protein 2, 48kDa0.249
CNOT3CCR4-NOT transcription complex, subunit 30.248
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.248
CCNE2cyclin E20.245
XRCC5X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)0.243
COPS8COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)0.230
ORC1origin recognition complex, subunit 10.226
CASP2caspase 2, apoptosis-related cysteine peptidase0.224
IER3immediate early response 30.222
NBNnibrin0.222
PPP2R5Bprotein phosphatase 2, regulatory subunit B', beta0.215
CHAF1Achromatin assembly factor 1, subunit A (p150)0.203
UBE2Mubiquitin-conjugating enzyme E2M (UBC12 homolog, yeast)0.200
OTUB1OTU domain, ubiquitin aldehyde binding 10.199
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.197
ATF3activating transcription factor 30.197
CDK1cyclin-dependent kinase 10.195
TP53BP1tumor protein p53 binding protein 10.194
CDC20cell division cycle 20 homolog (S. cerevisiae)0.193
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.188
RAD9ARAD9 homolog A (S. pombe)0.183
SENP3SUMO1/sentrin/SMT3 specific peptidase 30.178
FOXM1forkhead box M10.177
DTLdenticleless homolog (Drosophila)0.177
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
rnr-1Protein RNR-10.145
imb-2Protein IMB-20.071
csn-3Protein CSN-30.069
brc-1Protein BRC-10.065
his-45Protein HIS-450.051
hcf-1Protein HCF-10.051
T28D9.4Protein T28D9.40.048
egl-18Protein EGL-180.048
bub-1Protein BUB-10.041
lmn-1Protein LMN-10.039
B0205.9Protein B0205.90.036
cep-1Protein CEP-10.036
D1081.8Protein D1081.80.034
cin-4Protein CIN-40.033
lex-1Protein LEX-10.032
his-6Protein HIS-60.028
mat-3Protein MAT-30.026
CELE_C24H12.5Protein C24H12.50.026
sas-6Protein SAS-60.026
Y59E9AL.4Protein Y59E9AL.40.025
rod-1Protein ROD-10.024
pcn-1Protein PCN-10.022
nra-1Protein NRA-10.021
npp-16Protein NPP-160.021
npp-21Protein NPP-210.020
cyb-2.1Protein CYB-2.10.020
htz-1Protein HTZ-10.020
wht-7Protein WHT-70.019
csn-1Protein CSN-10.019
rps-15Protein RPS-150.018
sas-5Protein SAS-50.018
hsr-9Protein HSR-90.018
tba-2Protein TBA-20.017
set-1Protein SET-10.017
isw-1Protein ISW-10.016
cul-1Protein CUL-10.016
F20A1.9Protein F20A1.90.016
his-42Protein HIS-420.015
hpo-10Protein HPO-100.015
npp-11Protein NPP-110.015
uaf-1Protein UAF-10.015
rpa-1Protein RPA-10.014
hpo-9Protein HPO-90.014
mcm-5Protein MCM-50.014
emb-5Protein EMB-50.014
T22C1.1Protein T22C1.10.014
him-10Protein HIM-100.014
dpl-1Protein DPL-10.014
lin-9Protein LIN-90.014
C30A5.3Protein C30A5.30.013
dsh-2Protein DSH-20.013
hcp-1Protein HCP-10.012
fic-1Protein FIC-10.012
T05E8.3Protein T05E8.30.012
mex-5Protein MEX-50.012
pri-2Protein PRI-20.011
F25B3.6Protein F25B3.60.011
klp-19Protein KLP-190.011
cul-2Protein CUL-20.011
spt-5Protein SPT-50.011
ZK507.6Protein ZK507.60.010
rev-1Protein REV-10.010
csn-2Protein CSN-20.010
panl-2Protein PANL-20.010
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
pcnaproliferating cell nuclear antigen0.235
ccnd1cyclin D10.214
ywhaqbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide b0.205
ywhae1tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide 10.139
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.136
stilTAL1 (SCL) interrupting locus0.130
aurkbaurora kinase B0.123
ccnb1cyclin B10.112
mycamyelocytomatosis oncogene a0.100
brd2abromodomain-containing 2a0.092
ywhabbtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b0.080
cand1cullin-associated and neddylation-dissociated 10.072
mobkl3MOB1, Mps One Binder kinase activator-like 3 (yeast)0.067
plk1polo-like kinase 1 (Drosophila)0.063
tgif1TGFB-induced factor homeobox 10.059
kpna2karyopherin alpha 2 (RAG cohort 1, importin alpha 1)0.051
ccnb2cyclin B20.047
fen1flap structure-specific endonuclease 10.046
ywhaqatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide a0.044
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.042
chaf1bchromatin assembly factor 1, subunit B0.041
zff9zinc finger protein 90.038
tfamtranscription factor A, mitochondrial0.038
sumo3aSMT3 suppressor of mif two 3 homolog 3a0.037
aurkaaurora kinase A0.036
ywhabltyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide like0.036
cdk8cyclin-dependent kinase 80.036
rhoabras homolog gene family, member Ab0.035
si:ch211-59d15.5si:ch211-59d15.50.034
rad21RAD21 homolog (S. pombe)0.033
ppp2r1aprotein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform0.033
ncapgnon-SMC condensin I complex, subunit G0.029
ywhabatyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a0.028
ube2g2ubiquitin-conjugating enzyme E2G 20.028
atrxalpha thalassemia/mental retardation syndrome X-linked homolog (human)0.028
ccna2cyclin A20.028
g2e3G2/M-phase specific E3 ubiquitin ligase0.027
smc3structural maintenance of chromosomes 30.025
chek1CHK1 checkpoint homolog (S. pombe)0.024
hugHuG0.023
esco2establishment of cohesion 1 homolog 20.023
rrm1ribonucleotide reductase M1 polypeptide0.023
ybx1Y box binding protein 10.023
ppp2r5ebprotein phosphatase 2, regulatory subunit B', epsilon isoform b0.022
tbc1d23TBC1 domain family, member 230.022
pak2bp21 (CDKN1A)-activated kinase 2b0.022
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.022
rpl7aribosomal protein L7a0.022
gnb2l1guanine nucleotide binding protein (G protein), beta polypeptide 2-like 10.022
fabp7afatty acid binding protein 7, brain, a0.022
naa15bN(alpha)-acetyltransferase 15, NatA auxiliary subunit b0.021
snrpd1small nuclear ribonucleoprotein D1 polypeptide0.021
sass6spindle assembly 6 homolog (C. elegans)0.020
mdm2transformed 3T3 cell double minute 2 homolog (mouse)0.020
cstf1cleavage stimulation factor, 3' pre-RNA, subunit 10.020
ing5binhibitor of growth family, member 5b0.020
tia1cytotoxic granule-associated RNA binding protein 10.020
gdf6agrowth differentiation factor 6a0.019
id2ainhibitor of DNA binding 2, dominant negative helix-loop-helix protein, a0.019
kif23kinesin family member 230.018
ck2bcasein kinase 2 beta0.018
ube2i2ubiquitin-conjugating enzyme E2I20.017
wu:fq41a10wu:fq41a100.016
rqcd1RCD1 required for cell differentiation1 homolog (S. pombe)0.016
orc6origin recognition complex, subunit 60.016
caprin1acell cycle associated protein 1a0.016
srsf1aserine/arginine-rich splicing factor 1a0.015
lsm8LSM8 homolog, U6 small nuclear RNA associated0.015
smc1alstructural maintenance of chromosomes 1A, like0.015
cul3acullin 3a0.015
crip2cysteine-rich protein 20.015
dtldenticleless homolog (Drosophila)0.014
rasl11bRAS-like, family 11, member B0.014
dnmt5DNA (cytosine-5-)-methyltransferase 50.014
usp4ubiquitin specific protease 4 (proto-oncogene)0.014
csnk1g2bcasein kinase 1, gamma 2b0.014
smc4structural maintenance of chromosomes 40.014
eif2deukaryotic translation initiation factor 2D0.014
naspnuclear autoantigenic sperm protein (histone-binding)0.014
skp2S-phase kinase-associated protein 2 (p45)0.013
prkrirprotein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)0.013
cdt1chromatin licensing and DNA replication factor 10.013
dctdopachrome tautomerase0.013
kif14kinesin family member 140.013
ncapd2non-SMC condensin I complex, subunit D20.013
lrwd1leucine-rich repeats and WD repeat domain containing 10.013
acp5aacid phosphatase 5a, tartrate resistant0.012
msh6mutS homolog 6 (E. coli)0.012
tmem167atransmembrane protein 167A0.012
cdc20cell division cycle 20 homolog0.012
ccnt2bcyclin T2b0.012
zgc:101598zgc:1015980.012
prim1primase polypeptide 10.012
ccnecyclin E0.012
mab21l1mab-21-like 10.012
crklv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.012
celsr3cadherin, EGF LAG seven-pass G-type receptor 30.011
wdr82WD repeat domain containing 820.011
mapk3mitogen-activated protein kinase 30.011
zgc:113183zgc:1131830.011
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
p53CG33336 gene product from transcript CG33336-RB0.923
Pp1-87BProtein phosphatase 1 at 87B0.881
lokloki0.875
Pp2A-29BProtein phosphatase 2A at 29B0.872
DrefDNA replication-related element factor0.858
skpACG16983 gene product from transcript CG16983-RD0.855
MED6Mediator complex subunit 60.847
rad50CG6339 gene product from transcript CG6339-RD0.839
RanGapRan GTPase activating protein0.811
CSN5COP9 complex homolog subunit 50.805
mus205mutagen-sensitive 2050.793
poloCG12306 gene product from transcript CG12306-RA0.784
aspabnormal spindle0.762
IswiImitation SWI0.723
DNApol-etaCG7143 gene product from transcript CG7143-RA0.695
cdc2CG5363 gene product from transcript CG5363-RA0.683
Rcd1Reduction in Cnn dots 10.676
Brca2Breast cancer 2, early onset homolog0.655
CSN3COP9 complex homolog subunit 30.654
cdc2cCG10498 gene product from transcript CG10498-RC0.642
Vap-33-1CG5014 gene product from transcript CG5014-RB0.608
picpiccolo0.607
BRWD3CG31132 gene product from transcript CG31132-RA0.602
CG13298CG13298 gene product from transcript CG13298-RA0.589
imdimmune deficiency0.588
LnkCG17367 gene product from transcript CG17367-RC0.587
scnyscrawny0.585
hayhaywire0.575
Bap55Brahma associated protein 55kD0.571
tefutelomere fusion0.553
Nup50Nucleoporin 500.549
polyCG9829 gene product from transcript CG9829-RB0.520
Cdc37CG12019 gene product from transcript CG12019-RA0.464
Tip60CG6121 gene product from transcript CG6121-RA0.439
CG15141CG15141 gene product from transcript CG15141-RA0.436
CG4699CG4699 gene product from transcript CG4699-RJ0.425
CSN7COP9 complex homolog subunit 70.425
cdmcadmus0.405
chicoCG5686 gene product from transcript CG5686-RB0.385
CG5524CG5524 gene product from transcript CG5524-RA0.372
borrborealin-related0.372
CSN4COP9 complex homolog subunit 40.361
Spc105RSpc105-related0.360
okrokra0.351
CkIIbetaCasein kinase II beta subunit0.344
mus304mutagen-sensitive 3040.341
ncdnon-claret disjunctional0.328
fzyfizzy0.325
Hdac3Histone deacetylase 30.319
Cap-GCG34438 gene product from transcript CG34438-RF0.312
Mcm7Minichromosome maintenance 70.311
dre4CG1828 gene product from transcript CG1828-RB0.310
Nup153Nucleoporin 1530.301
waplwings apart-like0.297
Klp3AKinesin-like protein at 3A0.292
glugluon0.284
CDC45LCG3658 gene product from transcript CG3658-RA0.274
cnncentrosomin0.274
Akt1CG4006 gene product from transcript CG4006-RA0.269
eIF4AIIICG7483 gene product from transcript CG7483-RA0.258
Mcm10Sensitized chromosome inheritance modifier 190.255
alphaTub67Calpha-Tubulin at 67C0.255
CG9772CG9772 gene product from transcript CG9772-RB0.254
TrnTransportin0.243
His2AvHistone H2A variant0.239
CatCatalase0.232
CycB3Cyclin B30.230
l(2)NC136lethal (2) NC1360.225
trolterribly reduced optic lobes0.225
B52CG10851 gene product from transcript CG10851-RB0.223
CG34415CG34415 gene product from transcript CG34415-RC0.222
Sas-4CG10061 gene product from transcript CG10061-RA0.218
CSN8COP9 complex homolog subunit 80.213
gwlgreatwall0.213
piepineapple eye0.209
MED31Mediator complex subunit 310.209
flflfalafel0.205
RpII140RNA polymerase II 140kD subunit0.202
CHORDCG6198 gene product from transcript CG6198-RA0.201
magomago nashi0.198
KP78bCG17216 gene product from transcript CG17216-RB0.195
CG9797CG9797 gene product from transcript CG9797-RA0.194
SAKSak kinase0.194
SMC1CG6057 gene product from transcript CG6057-RA0.193
CG10754CG10754 gene product from transcript CG10754-RA0.192
CG10267CG10267 gene product from transcript CG10267-RB0.190
Srp54CG4602 gene product from transcript CG4602-RA0.188
mus308mutagen-sensitive 3080.188
tostosca0.188
alphalphabet0.185
mus301mutagen-sensitive 3010.184
Spt5CG7626 gene product from transcript CG7626-RA0.182
Cdk4Cyclin-dependent kinase 40.180
Liprin-alphaCG11199 gene product from transcript CG11199-RB0.179
Fcp1CG12252 gene product from transcript CG12252-RA0.177
CG9576CG9576 gene product from transcript CG9576-RA0.176
Caf1Chromatin assembly factor 1 subunit0.175
Uch-L3Ubiquitin C-terminal hydrolase0.174
matsmob as tumor suppressor0.173
pluplutonium0.167
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 531.000
Brca2breast cancer 20.912
Cdkn1bcyclin-dependent kinase inhibitor 1B0.847
Cdk4cyclin-dependent kinase 40.738
Brca1breast cancer 10.713
Ptenphosphatase and tensin homolog0.640
Rb1retinoblastoma 10.637
E2f1E2F transcription factor 10.634
Cdk1cyclin-dependent kinase 10.631
Mdm2transformed mouse 3T3 cell double minute 20.587
Mdm4transformed mouse 3T3 cell double minute 40.493
Rbl1retinoblastoma-like 1 (p107)0.415
Prc1protein regulator of cytokinesis 10.382
Cenpkcentromere protein K0.371
Cdk2cyclin-dependent kinase 20.357
Ccna2cyclin A20.264
Kif20akinesin family member 20A0.248
Rpgrip1lRpgrip1-like0.242
Suz12suppressor of zeste 12 homolog (Drosophila)0.225
Mis18bp1MIS18 binding protein 10.220
Aurkbaurora kinase B0.206
Gps1G protein pathway suppressor 10.205
Ppp1ccprotein phosphatase 1, catalytic subunit, gamma isoform0.198
SkilSKI-like0.198
Mcm2minichromosome maintenance deficient 2 mitotin (S. cerevisiae)0.187
Nde1nuclear distribution gene E homolog 1 (A nidulans)0.187
Cdkn2ccyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)0.182
Kif22kinesin family member 220.175
Crkv-crk sarcoma virus CT10 oncogene homolog (avian)0.174
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.172
Tcf3transcription factor 30.164
Kif23kinesin family member 230.161
Top2atopoisomerase (DNA) II alpha0.158
Gtse1G two S phase expressed protein 10.141
Ccnfcyclin F0.135
Eif2c2eukaryotic translation initiation factor 2C, 20.133
Ctnnb1catenin (cadherin associated protein), beta 10.129
Nf1neurofibromatosis 10.125
Sirt1sirtuin 1 (silent mating type information regulation 2, homolog) 1 (S. cerevisiae)0.120
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.116
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.113
Dlgap5discs, large (Drosophila) homolog-associated protein 50.106
Ccnb2cyclin B20.103
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.101
Aurkaaurora kinase A0.100
Apcadenomatosis polyposis coli0.100
Naspnuclear autoantigenic sperm protein (histone-binding)0.100
Smc2structural maintenance of chromosomes 20.099
Ccdc99coiled-coil domain containing 990.099
Kif11kinesin family member 110.097
Kif2ckinesin family member 2C0.097
C330027C09RikRIKEN cDNA C330027C09 gene0.096
Mybl2myeloblastosis oncogene-like 20.095
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.094
Smc3structural maintenace of chromosomes 30.090
Egr2early growth response 20.088
Rararetinoic acid receptor, alpha0.088
Cdc45cell division cycle 45 homolog (S. cerevisiae)0.088
Smad4MAD homolog 4 (Drosophila)0.086
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.085
Rnf2ring finger protein 20.084
Acdadrenocortical dysplasia0.083
Trp73transformation related protein 730.083
Lig1ligase I, DNA, ATP-dependent0.082
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.080
Birc5baculoviral IAP repeat-containing 50.079
Elavl1ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)0.077
Kat2aK(lysine) acetyltransferase 2A0.077
Dtldenticleless homolog (Drosophila)0.077
Gpi1glucose phosphate isomerase 10.077
Ccnb1cyclin B10.075
Ruvbl2RuvB-like protein 20.073
Cdkn1acyclin-dependent kinase inhibitor 1A (P21)0.072
Msh2mutS homolog 2 (E. coli)0.070
Ckap2cytoskeleton associated protein 20.070
Hmgb1high mobility group box 10.069
CrebbpCREB binding protein0.068
Nup107nucleoporin 1070.067
Ptch1patched homolog 10.067
Topbp1topoisomerase (DNA) II binding protein 10.066
Tmpothymopoietin0.066
Pou5f1POU domain, class 5, transcription factor 10.066
Kif4kinesin family member 40.066
Sae1SUMO1 activating enzyme subunit 10.063
Pkm2pyruvate kinase, muscle0.061
Nbnnibrin0.059
Sp1trans-acting transcription factor 10.059
Trp63transformation related protein 630.059
Ccnd1cyclin D10.059
Lin9lin-9 homolog (C. elegans)0.058
Tcf19transcription factor 190.057
Mlh1mutL homolog 1 (E. coli)0.056
Spag5sperm associated antigen 50.056
Tpi1triosephosphate isomerase 10.056
Ccne1cyclin E10.055
Rad51ap1RAD51 associated protein 10.055
Asf1bASF1 anti-silencing function 1 homolog B (S. cerevisiae)0.055
Mcm3minichromosome maintenance deficient 3 (S. cerevisiae)0.054
Xpaxeroderma pigmentosum, complementation group A0.054
Mitfmicrophthalmia-associated transcription factor0.054
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pkm2pyruvate kinase, muscle0.051
Racgap1Rac GTPase-activating protein 10.051
Spc25SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)0.040
Hmmrhyaluronan mediated motility receptor (RHAMM)0.039
Tnks2tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 20.034
Pcyox1prenylcysteine oxidase 10.031
Top2atopoisomerase (DNA) II alpha0.030
Tcp11l2t-complex 11 (mouse) like 20.029
Kif2ckinesin family member 2C0.028
Zfand5zinc finger, AN1-type domain 50.026
Ptbp1polypyrimidine tract binding protein 10.025
Ppp1caprotein phosphatase 1, catalytic subunit, alpha isoform0.025
Bub1bbudding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)0.024
Ppp1cbprotein phosphatase 1, catalytic subunit, beta isoform0.024
Mdm2Mdm2 p53 binding protein homolog (mouse)0.023
Ect2epithelial cell transforming sequence 2 oncogene0.023
Sesn1sestrin 10.023
Pdp1pyruvate dehyrogenase phosphatase catalytic subunit 10.022
Traf4af1TRAF4 associated factor 10.022
Zfand6zinc finger, AN1-type domain 60.021
Cdca3cell division cycle associated 30.021
Serinc1serine incorporator 10.021
Cdk4cyclin-dependent kinase 40.021
Scamp2secretory carrier membrane protein 20.020
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.020
Bcl2l2Bcl2-like 20.020
Mak10MAK10 homolog, amino-acid N-acetyltransferase subunit, (S. cerevisiae)0.019
Tcf12transcription factor 120.019
Cdca4cell division cycle associated 40.019
Rpa2replication protein A20.019
Rbbp7retinoblastoma binding protein 70.019
Dnaja2DnaJ (Hsp40) homolog, subfamily A, member 20.019
Ccnb2cyclin B20.018
Rilreversion induced LIM gene0.018
Prkacbprotein kinase, cAMP dependent, catalytic, beta0.018
Bnip3lBCL2/adenovirus E1B interacting protein 3-like0.018
LOC100364212heterogeneous nuclear ribonucleoprotein K-like0.018
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.018
Cdca7cell division cycle associated 70.017
Fundc1FUN14 domain containing 10.017
Necap2NECAP endocytosis associated 20.017
Aurkbaurora kinase B0.017
Gnb2guanine nucleotide binding protein (G protein), beta polypeptide 20.017
Ccnd3cyclin D30.017
Sepw1selenoprotein W, 10.017
Dlg3discs, large homolog 3 (Drosophila)0.016
Usp9xubiquitin specific peptidase 9, X-linked0.016
Tob1transducer of ErbB-2.10.016
Txndc15thioredoxin domain containing 150.016
Hbp1HMG-box transcription factor 10.016
Pctk2PCTAIRE protein kinase 20.016
Rrm2ribonucleotide reductase M20.016
Nos3nitric oxide synthase 3, endothelial cell0.016
Bak1BCL2-antagonist/killer 10.016
Ube2tubiquitin-conjugating enzyme E2T (putative)0.016
Stx7syntaxin 70.015
Zyxzyxin0.015
Ccng2cyclin G20.015
Ccnicyclin I0.015
Prim2primase, DNA, polypeptide 20.015
Vegfavascular endothelial growth factor A0.015
Acyp2acylphosphatase 2, muscle type0.015
Ube2cubiquitin-conjugating enzyme E2C0.015
Ccdc99coiled-coil domain containing 990.015
Troaptrophinin associated protein0.015
Cdca8cell division cycle associated 80.015
Zhx1zinc fingers and homeoboxes 10.015
Cdkn3cyclin-dependent kinase inhibitor 30.015
Stxbp3syntaxin binding protein 30.015
Zbtb6zinc finger and BTB domain containing 60.015
OgtO-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)0.015
Tm2d2TM2 domain containing 20.015
Asna1arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)0.015
Cul3cullin 30.014
Ubl3ubiquitin-like 30.014
Daxxdeath-domain associated protein0.014
Prkd3protein kinase D30.014
Pola1polymerase (DNA directed), alpha 10.014
Gpiglucose phosphate isomerase0.014
Atp5bATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide0.014
Ccnb1cyclin B10.014
Ythdf3YTH domain family, member 30.014
Top2btopoisomerase (DNA) II beta0.014
Fam116afamily with sequence similarity 116, member A0.014
Ndrg2N-myc downstream regulated gene 20.014
Mrpl38mitochondrial ribosomal protein L380.014
Dctn4dynactin 40.014
Nudt3nudix (nucleoside diphosphate linked moiety X)-type motif 30.014
Pcmtd2protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 20.014
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.014
Tln1talin 10.014
Tmpothymopoietin0.014
Znf467zinc finger protein 4670.014
Sh3yl1SH3 domain containing, Ysc84-like 1 (S. cerevisiae)0.014
Gcs1glucosidase 10.014
Pctk1PCTAIRE protein kinase 10.014
Tmco3transmembrane and coiled-coil domains 30.014
Brms1lbreast cancer metastasis-suppressor 1-like0.014
Dhfrdihydrofolate reductase0.013
Prdm4PR domain containing 40.013
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
GLC7Glc7p0.979
MAD2Mad2p0.831
GIC1Gic1p0.742
SLK19Slk19p0.725
KEL1Kel1p0.694
RAD53Rad53p0.657
CDC55Cdc55p0.651
BUB3Bub3p0.553
PPH22Pph22p0.485
PPH21Pph21p0.467
BCK1Bck1p0.460
DBF4Dbf4p0.455
RAD52Rad52p0.415
CDC6Cdc6p0.367
CTF18Ctf18p0.333
SIC1Sic1p0.333
CDC28Cdc28p0.319
BUB1Bub1p0.314
SPT5Spt5p0.306
ZDS2Zds2p0.303
CKA1Cka1p0.299
CDC20Cdc20p0.291
MCM21Mcm21p0.283
CDC14Cdc14p0.276
BMH2Bmh2p0.269
RTS1Rts1p0.261
DIA2Dia2p0.234
TFG1Tfg1p0.230
MCD1Mcd1p0.211
BFA1Bfa1p0.210
DPB2Dpb2p0.191
CHL1Chl1p0.191
PPZ1Ppz1p0.186
CTF4Ctf4p0.185
CTF13Ctf13p0.184
NUD1Nud1p0.177
BMH1Bmh1p0.174
IML3Iml3p0.174
FMP48Fmp48p0.174
SMC4Smc4p0.170
CSE4Cse4p0.167
DUN1Dun1p0.166
SDS22Sds22p0.163
ELG1Elg1p0.161
RPO26Rpo26p0.160
POL30Pol30p0.157
CLB6Clb6p0.155
KIN3Kin3p0.152
SLI15Sli15p0.144
BIM1Bim1p0.141
NOP6Nop6p0.138
FAR1Far1p0.133
GBP2Gbp2p0.132
RPB3Rpb3p0.126
LCD1Lcd1p0.123
RCO1Rco1p0.119
MAD3Mad3p0.118
SCC2Scc2p0.115
SET1Set1p0.112
MCM10Mcm10p0.111
PDS1Pds1p0.111
CIN1Cin1p0.110
KIC1Kic1p0.109
CKS1Cks1p0.109
MRC1Mrc1p0.106
REG1Reg1p0.106
CLA4Cla4p0.105
PEX22Pex22p0.103
DSN1Dsn1p0.099
CLB1Clb1p0.098
GSY2Gsy2p0.098
DMA2Dma2p0.098
PLC1Plc1p0.097
POL1Pol1p0.094
SGO1Sgo1p0.094
RAD9Rad9p0.093
MAD1Mad1p0.090
SRS2Srs2p0.090
PCL10Pcl10p0.089
MCM6Mcm6p0.088
PDS5Pds5p0.086
IST1Ist1p0.086
RRM3Rrm3p0.084
STU1Stu1p0.084
TID3Tid3p0.081
CDC12Cdc12p0.080
EAF1Eaf1p0.079
CDC15Cdc15p0.079
RNH202Rnh202p0.078
MOB2Mob2p0.078
HSL1Hsl1p0.076
CTF3Ctf3p0.076
MPT5Mpt5p0.076
KIN1Kin1p0.074
MCM2Mcm2p0.074
SKM1Skm1p0.074
POL2Pol2p0.073
GPH1Gph1p0.073
DEF1Def1p0.072
ZDS1Zds1p0.071