The network for 'ventricular septum morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

ventricular septum morphogenesis

The developmental process in which a ventricular septum is generated and organized. A ventricular septum is an anatomical structure that separates the lower chambers (ventricles) of the heart from one another.

NameDescriptionProbabilityFunc Analog Organism
JAG1jagged 11.000
SMAD3SMAD family member 30.994
FGF1fibroblast growth factor 1 (acidic)0.960
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.803
TBX5T-box 50.786
CXXC5CXXC finger protein 50.643
FGF10fibroblast growth factor 100.629
STK3serine/threonine kinase 30.583
SKILSKI-like oncogene0.536
AXIN1axin 10.521
NR4A1nuclear receptor subfamily 4, group A, member 10.473
DLL1delta-like 1 (Drosophila)0.448
XRCC6X-ray repair complementing defective repair in Chinese hamster cells 60.447
EPAS1endothelial PAS domain protein 10.445
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.408
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.405
JAG2jagged 20.327
GSK3Bglycogen synthase kinase 3 beta0.325
MAML1mastermind-like 1 (Drosophila)0.309
SMAD9SMAD family member 90.306
EP300E1A binding protein p3000.299
XIAPX-linked inhibitor of apoptosis0.298
CSNK1Ecasein kinase 1, epsilon0.274
NOTCH1notch 10.270
WNT3Awingless-type MMTV integration site family, member 3A0.248
RBBP4retinoblastoma binding protein 40.242
SMAD1SMAD family member 10.207
NOTCH2notch 20.188
SOX7SRY (sex determining region Y)-box 70.155
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.137
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.118
FZD1frizzled homolog 1 (Drosophila)0.111
GATA4GATA binding protein 40.101
FGF7fibroblast growth factor 70.091
DKK1dickkopf homolog 1 (Xenopus laevis)0.087
MARCKSL1MARCKS-like 10.082
PAX8paired box 80.081
WNT5Awingless-type MMTV integration site family, member 5A0.081
EGLN3egl nine homolog 3 (C. elegans)0.079
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.077
PIAS4protein inhibitor of activated STAT, 40.075
NOTCH3notch 30.075
CTBP2C-terminal binding protein 20.067
LRRK2leucine-rich repeat kinase 20.066
SIRT1sirtuin 10.064
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.060
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.057
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.056
ARID1BAT rich interactive domain 1B (SWI1-like)0.049
RASSF3Ras association (RalGDS/AF-6) domain family member 30.049
SMURF2SMAD specific E3 ubiquitin protein ligase 20.048
ID3inhibitor of DNA binding 3, dominant negative helix-loop-helix protein0.048
LAPTM5lysosomal protein transmembrane 50.048
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.047
STK4serine/threonine kinase 40.046
SEC16ASEC16 homolog A (S. cerevisiae)0.045
EGFL7EGF-like-domain, multiple 70.045
AMMECR1Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 10.043
RASSF2Ras association (RalGDS/AF-6) domain family member 20.040
NOTCH2NLnotch 2 N-terminal like0.040
SMAD7SMAD family member 70.039
TAL1T-cell acute lymphocytic leukemia 10.036
POU3F2POU class 3 homeobox 20.034
RASSF5Ras association (RalGDS/AF-6) domain family member 50.033
BICD1bicaudal D homolog 1 (Drosophila)0.032
MAPK8mitogen-activated protein kinase 80.031
PTK2PTK2 protein tyrosine kinase 20.031
DVL1dishevelled, dsh homolog 1 (Drosophila)0.030
MCCmutated in colorectal cancers0.030
EVC2Ellis van Creveld syndrome 20.030
SOX9SRY (sex determining region Y)-box 90.030
NINninein (GSK3B interacting protein)0.030
DAB2disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)0.029
NEDD9neural precursor cell expressed, developmentally down-regulated 90.028
PAPPApregnancy-associated plasma protein A, pappalysin 10.028
NR5A2nuclear receptor subfamily 5, group A, member 20.027
SNW1SNW domain containing 10.027
FZD7frizzled homolog 7 (Drosophila)0.026
WWP2WW domain containing E3 ubiquitin protein ligase 20.026
RBPMSRNA binding protein with multiple splicing0.026
ARNTaryl hydrocarbon receptor nuclear translocator0.026
FAM110Cfamily with sequence similarity 110, member C0.025
FBLN1fibulin 10.024
FGFR1fibroblast growth factor receptor 10.024
MAPTmicrotubule-associated protein tau0.024
FAM110Afamily with sequence similarity 110, member A0.024
SNAI1snail homolog 1 (Drosophila)0.024
PABPN1poly(A) binding protein, nuclear 10.023
STK38Lserine/threonine kinase 38 like0.023
TAOK1TAO kinase 10.023
ID4inhibitor of DNA binding 4, dominant negative helix-loop-helix protein0.023
PDGFCplatelet derived growth factor C0.022
YAP1Yes-associated protein 10.022
FZD8frizzled homolog 8 (Drosophila)0.022
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.022
LMO4LIM domain only 40.022
BAZ1Bbromodomain adjacent to zinc finger domain, 1B0.022
TCF4transcription factor 40.022
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Foxc1forkhead box C11.000
Jag1jagged 11.000
Fgf8fibroblast growth factor 81.000
Fgfr2fibroblast growth factor receptor 21.000
Shhsonic hedgehog1.000
Pax2paired box gene 21.000
Pitx2paired-like homeodomain transcription factor 21.000
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Bmp4bone morphogenetic protein 41.000
Pax3paired box gene 30.999
Gli3GLI-Kruppel family member GLI30.999
Ctnnb1catenin (cadherin associated protein), beta 10.999
Fgfr1fibroblast growth factor receptor 10.999
Foxc2forkhead box C20.998
Hand2heart and neural crest derivatives expressed transcript 20.998
Gata4GATA binding protein 40.998
Tgfb2transforming growth factor, beta 20.998
Vegfavascular endothelial growth factor A0.996
Otx2orthodenticle homolog 2 (Drosophila)0.995
Tbx3T-box 30.995
Ptpn11protein tyrosine phosphatase, non-receptor type 110.992
Hes1hairy and enhancer of split 1 (Drosophila)0.989
Tbx1T-box 10.988
Fgf10fibroblast growth factor 100.986
Rargretinoic acid receptor, gamma0.982
Sox2SRY-box containing gene 20.982
Rxraretinoid X receptor alpha0.981
Smad6MAD homolog 6 (Drosophila)0.975
Hey2hairy/enhancer-of-split related with YRPW motif 20.975
Meox2mesenchyme homeobox 20.968
Hoxa1homeobox A10.958
Efnb2ephrin B20.956
Rarbretinoic acid receptor, beta0.951
Lhx1LIM homeobox protein 10.945
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.936
Bmpr1abone morphogenetic protein receptor, type 1A0.935
Eya1eyes absent 1 homolog (Drosophila)0.924
Tcfap2atranscription factor AP-2, alpha0.911
Egfrepidermal growth factor receptor0.907
Hand1heart and neural crest derivatives expressed transcript 10.905
Pitx1paired-like homeodomain transcription factor 10.884
Notch1Notch gene homolog 1 (Drosophila)0.875
Sox4SRY-box containing gene 40.874
Id3inhibitor of DNA binding 30.865
Gli2GLI-Kruppel family member GLI20.861
Chd7chromodomain helicase DNA binding protein 70.844
Foxg1forkhead box G10.840
Dlx5distal-less homeobox 50.840
Wnt3awingless-related MMTV integration site 3A0.838
Scn5asodium channel, voltage-gated, type V, alpha0.838
Pax6paired box gene 60.835
Gata6GATA binding protein 60.834
Notch2Notch gene homolog 2 (Drosophila)0.819
Ntf3neurotrophin 30.806
Smosmoothened homolog (Drosophila)0.771
Acvr1activin A receptor, type 10.769
Nos3nitric oxide synthase 3, endothelial cell0.745
Itgb1integrin beta 1 (fibronectin receptor beta)0.718
Hey1hairy/enhancer-of-split related with YRPW motif 10.699
Vangl2vang-like 2 (van gogh, Drosophila)0.698
Gja5gap junction protein, alpha 50.692
Axin1axin 10.689
Sox11SRY-box containing gene 110.683
Prrx1paired related homeobox 10.675
Msx2homeobox, msh-like 20.672
Apcadenomatosis polyposis coli0.664
Tbx5T-box 50.659
Zeb1zinc finger E-box binding homeobox 10.649
Rararetinoic acid receptor, alpha0.648
Mesp1mesoderm posterior 10.641
Twist2twist homolog 2 (Drosophila)0.637
Lrp6low density lipoprotein receptor-related protein 60.624
Tbx2T-box 20.616
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.592
Hoxd13homeobox D130.585
Msx1homeobox, msh-like 10.583
Nfatc4nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 40.572
Ptenphosphatase and tensin homolog0.571
Dvl2dishevelled 2, dsh homolog (Drosophila)0.569
Smad3MAD homolog 3 (Drosophila)0.545
Hoxa13homeobox A130.512
Emx2empty spiracles homolog 2 (Drosophila)0.511
Id1inhibitor of DNA binding 10.496
Hes5hairy and enhancer of split 5 (Drosophila)0.488
Ror2receptor tyrosine kinase-like orphan receptor 20.487
Dkk1dickkopf homolog 1 (Xenopus laevis)0.486
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.484
Hspg2perlecan (heparan sulfate proteoglycan 2)0.462
Otx1orthodenticle homolog 1 (Drosophila)0.462
Lmx1bLIM homeobox transcription factor 1 beta0.459
Foxh1forkhead box H10.458
Wt1Wilms tumor 1 homolog0.455
Klf3Kruppel-like factor 3 (basic)0.453
Gpc3glypican 30.446
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.438
Prrx2paired related homeobox 20.430
Adam17a disintegrin and metallopeptidase domain 170.418
Isl1ISL1 transcription factor, LIM/homeodomain0.403
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism