The network for 'regulation of spindle checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of spindle checkpoint

Any process that modulates the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.

NameDescriptionProbabilityFunc Analog Organism
RANRAN, member RAS oncogene family0.063
DDX18DEAD (Asp-Glu-Ala-Asp) box polypeptide 180.033
AURKAaurora kinase A0.031
UBCubiquitin C0.031
MAD2L1MAD2 mitotic arrest deficient-like 1 (yeast)0.027
MCM7minichromosome maintenance complex component 70.023
ILF3interleukin enhancer binding factor 3, 90kDa0.021
RPS3Aribosomal protein S3A0.021
RPS16ribosomal protein S160.021
CCT3chaperonin containing TCP1, subunit 3 (gamma)0.021
RPS6ribosomal protein S60.020
EIF4A3eukaryotic translation initiation factor 4A30.018
NOP56NOP56 ribonucleoprotein homolog (yeast)0.018
SNRPBsmall nuclear ribonucleoprotein polypeptides B and B10.017
NPM1nucleophosmin (nucleolar phosphoprotein B23, numatrin)0.016
RPL17ribosomal protein L170.015
RPS7ribosomal protein S70.015
RPL5ribosomal protein L50.015
RPS2ribosomal protein S20.014
RPL6ribosomal protein L60.014
RPL24ribosomal protein L240.013
MCM3minichromosome maintenance complex component 30.013
MRPL3mitochondrial ribosomal protein L30.013
RPL15ribosomal protein L150.013
PAICSphosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase0.013
RPL7ribosomal protein L70.013
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 140.013
FBLfibrillarin0.013
ICT1immature colon carcinoma transcript 10.013
RPSAribosomal protein SA0.013
TRIM28tripartite motif containing 280.012
RPS8ribosomal protein S80.011
RPS17ribosomal protein S170.011
RPS3ribosomal protein S30.011
EBNA1BP2EBNA1 binding protein 20.011
RPL21ribosomal protein L210.011
PSMA4proteasome (prosome, macropain) subunit, alpha type, 40.011
PSMD1proteasome (prosome, macropain) 26S subunit, non-ATPase, 10.011
HSPA9heat shock 70kDa protein 9 (mortalin)0.011
GARTphosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase0.011
RPS19ribosomal protein S190.010
PRMT5protein arginine methyltransferase 50.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
DlDelta0.148
wgwingless0.118
NNotch0.097
Fas2Fasciclin 20.077
dppdecapentaplegic0.038
EgfrEpidermal growth factor receptor0.037
Rho1CG8416 gene product from transcript CG8416-RB0.030
TorTarget of rapamycin0.029
tkvthickveins0.029
hephemipterous0.027
armarmadillo0.027
DDichaete0.023
mxcmulti sex combs0.021
sggshaggy0.021
HHairless0.020
phlpole hole0.020
hhhedgehog0.019
Fmr1CG6203 gene product from transcript CG6203-RC0.018
shishibire0.017
ctcut0.016
edechinoid0.014
twstwins0.014
MadMothers against dpp0.014
CG5703CG5703 gene product from transcript CG5703-RA0.014
nejnejire0.013
Rac1CG2248 gene product from transcript CG2248-RA0.012
msnmisshapen0.012
spispitz0.011
mit(1)15mitotic 150.011
SerSerrate0.011
MhcMyosin heavy chain0.010
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nap1l1nucleosome assembly protein 1-like 10.014
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism