The network for 'positive regulation of spindle checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of spindle checkpoint

Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.

NameDescriptionProbabilityFunc Analog Organism
ICT1immature colon carcinoma transcript 10.043
UBCubiquitin C0.042
RUVBL2RuvB-like 2 (E. coli)0.037
EIF3Keukaryotic translation initiation factor 3, subunit K0.025
MRPL4mitochondrial ribosomal protein L40.024
UQCRQubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa0.023
COX5Bcytochrome c oxidase subunit Vb0.022
COPS6COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis)0.021
NHP2NHP2 ribonucleoprotein homolog (yeast)0.020
SNRPBsmall nuclear ribonucleoprotein polypeptides B and B10.019
CYC1cytochrome c-10.018
MRPL13mitochondrial ribosomal protein L130.017
AURKAaurora kinase A0.016
NDUFS3NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)0.016
COX6B1cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous)0.015
RALYRNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse))0.015
DCTPP1dCTP pyrophosphatase 10.014
UQCRC1ubiquinol-cytochrome c reductase core protein I0.014
HNRNPKheterogeneous nuclear ribonucleoprotein K0.014
TRIM28tripartite motif containing 280.014
STOML2stomatin (EPB72)-like 20.013
NDUFAB1NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa0.013
PHB2prohibitin 20.013
PUF60poly-U binding splicing factor 60KDa0.013
NDUFA13NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 130.012
SNRPD2small nuclear ribonucleoprotein D2 polypeptide 16.5kDa0.012
TUFMTu translation elongation factor, mitochondrial0.012
NEDD8neural precursor cell expressed, developmentally down-regulated 80.011
PA2G4proliferation-associated 2G4, 38kDa0.011
PRPF40APRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)0.011
C14orf2chromosome 14 open reading frame 20.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccnb1cyclin B10.013
Cdk1cyclin-dependent kinase 10.013
Birc5baculoviral IAP repeat-containing 50.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism