IMP
Process View
The network for 'positive regulation of spindle checkpoint' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.
Multiple Organisms
positive regulation of spindle checkpoint
Any process that increases the rate, frequency, or extent of the spindle checkpoint, a cell cycle checkpoint that delays the metaphase/anaphase transition until the spindle is correctly assembled and oriented, and chromosomes are attached to the spindle.
| Name | Description | Probability | Func Analog Organism |
|---|---|---|---|
| ICT1 | immature colon carcinoma transcript 1 | 0.043 | |
| UBC | ubiquitin C | 0.042 | |
| RUVBL2 | RuvB-like 2 (E. coli) | 0.037 | |
| EIF3K | eukaryotic translation initiation factor 3, subunit K | 0.025 | |
| MRPL4 | mitochondrial ribosomal protein L4 | 0.024 | |
| UQCRQ | ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa | 0.023 | |
| COX5B | cytochrome c oxidase subunit Vb | 0.022 | |
| COPS6 | COP9 constitutive photomorphogenic homolog subunit 6 (Arabidopsis) | 0.021 | |
| NHP2 | NHP2 ribonucleoprotein homolog (yeast) | 0.020 | |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.019 | |
| CYC1 | cytochrome c-1 | 0.018 | |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.017 | |
| AURKA | aurora kinase A | 0.016 | |
| NDUFS3 | NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) | 0.016 | |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) | 0.015 | |
| RALY | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 0.015 | |
| DCTPP1 | dCTP pyrophosphatase 1 | 0.014 | |
| UQCRC1 | ubiquinol-cytochrome c reductase core protein I | 0.014 | |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | 0.014 | |
| TRIM28 | tripartite motif containing 28 | 0.014 | |
| STOML2 | stomatin (EPB72)-like 2 | 0.013 | |
| NDUFAB1 | NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa | 0.013 | |
| PHB2 | prohibitin 2 | 0.013 | |
| PUF60 | poly-U binding splicing factor 60KDa | 0.013 | |
| NDUFA13 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 | 0.012 | |
| SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 0.012 | |
| TUFM | Tu translation elongation factor, mitochondrial | 0.012 | |
| NEDD8 | neural precursor cell expressed, developmentally down-regulated 8 | 0.011 | |
| PA2G4 | proliferation-associated 2G4, 38kDa | 0.011 | |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.011 | |
| C14orf2 | chromosome 14 open reading frame 2 | 0.010 |
