The network for 'regulation of lymphocyte proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of lymphocyte proliferation

Any process that modulates the frequency, rate or extent of lymphocyte proliferation.

NameDescriptionProbabilityFunc Analog Organism
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.991
CD80CD80 molecule0.967
FGFR2fibroblast growth factor receptor 20.966
LATlinker for activation of T cells0.961
BCL2B-cell CLL/lymphoma 20.961
PTPRCprotein tyrosine phosphatase, receptor type, C0.952
CD86CD86 molecule0.947
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.933
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.912
SHC1SHC (Src homology 2 domain containing) transforming protein 10.912
LILRB1leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 10.894
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.889
SOCS3suppressor of cytokine signaling 30.865
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.865
SYKspleen tyrosine kinase0.864
TRAF1TNF receptor-associated factor 10.853
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.852
HLA-Fmajor histocompatibility complex, class I, F0.851
IL1Binterleukin 1, beta0.848
PTPN6protein tyrosine phosphatase, non-receptor type 60.839
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.835
B2Mbeta-2-microglobulin0.829
LTAlymphotoxin alpha (TNF superfamily, member 1)0.826
HLA-DMBmajor histocompatibility complex, class II, DM beta0.823
BIRC3baculoviral IAP repeat containing 30.821
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.811
TRAF2TNF receptor-associated factor 20.789
IL4Rinterleukin 4 receptor0.785
HLA-Gmajor histocompatibility complex, class I, G0.779
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.769
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.769
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.766
HLA-Bmajor histocompatibility complex, class I, B0.764
LCKlymphocyte-specific protein tyrosine kinase0.739
ICAM1intercellular adhesion molecule 10.711
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.695
SH3BP2SH3-domain binding protein 20.686
PTPN1protein tyrosine phosphatase, non-receptor type 10.672
SLASrc-like-adaptor0.669
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.667
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.659
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.651
BTN3A1butyrophilin, subfamily 3, member A10.636
IL10RAinterleukin 10 receptor, alpha0.613
IL1R1interleukin 1 receptor, type I0.605
BTN3A3butyrophilin, subfamily 3, member A30.573
TICAM2toll-like receptor adaptor molecule 20.568
EGFRepidermal growth factor receptor0.530
CD247CD247 molecule0.524
HLA-DRB5major histocompatibility complex, class II, DR beta 50.517
BTN3A2butyrophilin, subfamily 3, member A20.515
PLCG1phospholipase C, gamma 10.488
CCR1chemokine (C-C motif) receptor 10.481
CCL4chemokine (C-C motif) ligand 40.471
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.468
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.464
HLA-Emajor histocompatibility complex, class I, E0.463
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.457
IL2RGinterleukin 2 receptor, gamma0.432
CCR5chemokine (C-C motif) receptor 50.431
IL6STinterleukin 6 signal transducer (gp130, oncostatin M receptor)0.430
TFF1trefoil factor 10.417
RHOUras homolog gene family, member U0.413
FGFR1fibroblast growth factor receptor 10.406
CXCL9chemokine (C-X-C motif) ligand 90.398
ITGALintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)0.392
FGF1fibroblast growth factor 1 (acidic)0.391
JAK1Janus kinase 10.383
CCR7chemokine (C-C motif) receptor 70.367
SIGLEC7sialic acid binding Ig-like lectin 70.364
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.360
CCL2chemokine (C-C motif) ligand 20.346
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.344
JAK2Janus kinase 20.336
IRF4interferon regulatory factor 40.334
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.334
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.325
INSRinsulin receptor0.321
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.320
BIDBH3 interacting domain death agonist0.319
HLA-Cmajor histocompatibility complex, class I, C0.318
HLA-DQB1major histocompatibility complex, class II, DQ beta 10.307
IFNGinterferon, gamma0.302
TNFRSF1Btumor necrosis factor receptor superfamily, member 1B0.299
IL2RBinterleukin 2 receptor, beta0.299
CASP9caspase 9, apoptosis-related cysteine peptidase0.297
HCKhemopoietic cell kinase0.295
IRAK1interleukin-1 receptor-associated kinase 10.281
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.273
GRB2growth factor receptor-bound protein 20.270
BCL2L11BCL2-like 11 (apoptosis facilitator)0.265
CLEC10AC-type lectin domain family 10, member A0.262
HLA-DRB4major histocompatibility complex, class II, DR beta 40.260
ABI1abl-interactor 10.259
BCL2A1BCL2-related protein A10.252
TNFRSF9tumor necrosis factor receptor superfamily, member 90.252
IL6interleukin 6 (interferon, beta 2)0.246
IRS1insulin receptor substrate 10.244
ABL1c-abl oncogene 1, non-receptor tyrosine kinase0.243
HLA-DPB1major histocompatibility complex, class II, DP beta 10.242
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lyz2lysozyme 20.999
Tnftumor necrosis factor0.999
Efnb2ephrin B20.998
Ptenphosphatase and tensin homolog0.997
Ptpn11protein tyrosine phosphatase, non-receptor type 110.996
Cd19CD19 antigen0.995
Il4interleukin 40.995
Tlr4toll-like receptor 40.988
Ccr2chemokine (C-C motif) receptor 20.986
FasFas (TNF receptor superfamily member 6)0.985
Cd40CD40 antigen0.984
Casp4caspase 4, apoptosis-related cysteine peptidase0.983
Trp53transformation related protein 530.979
Stat3signal transducer and activator of transcription 30.977
Ctnnb1catenin (cadherin associated protein), beta 10.971
Itgb1integrin beta 1 (fibronectin receptor beta)0.969
Foxp3forkhead box P30.967
Cd28CD28 antigen0.964
Leprleptin receptor0.963
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.954
Myd88myeloid differentiation primary response gene 880.950
Ighimmunoglobulin heavy chain complex0.940
Inpp5dinositol polyphosphate-5-phosphatase D0.938
Tnfrsf9tumor necrosis factor receptor superfamily, member 90.921
Ccr1chemokine (C-C motif) receptor 10.917
Ikzf1IKAROS family zinc finger 10.907
Foxc1forkhead box C10.899
FynFyn proto-oncogene0.893
Clec4nC-type lectin domain family 4, member n0.887
Rb1retinoblastoma 10.878
Nckap1lNCK associated protein 1 like0.877
Grb2growth factor receptor bound protein 20.871
Prkcdprotein kinase C, delta0.852
Pax8paired box gene 80.847
Ccr7chemokine (C-C motif) receptor 70.846
Nf1neurofibromatosis 10.834
Nr3c1nuclear receptor subfamily 3, group C, member 10.831
Fgfr2fibroblast growth factor receptor 20.829
Tnfaip3tumor necrosis factor, alpha-induced protein 30.827
Cd4CD4 antigen0.824
Ccl2chemokine (C-C motif) ligand 20.814
Cyldcylindromatosis (turban tumor syndrome)0.810
CblCasitas B-lineage lymphoma0.803
Cdkn1bcyclin-dependent kinase inhibitor 1B0.795
C3ar1complement component 3a receptor 10.793
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.791
Il10interleukin 100.780
Ltblymphotoxin B0.776
Casp1caspase 10.773
Ifnginterferon gamma0.771
Zeb1zinc finger E-box binding homeobox 10.763
Irf4interferon regulatory factor 40.762
BtkBruton agammaglobulinemia tyrosine kinase0.760
Ltalymphotoxin A0.740
Emx1empty spiracles homolog 1 (Drosophila)0.738
Hif1ahypoxia inducible factor 1, alpha subunit0.735
Siglec1sialic acid binding Ig-like lectin 1, sialoadhesin0.735
Card11caspase recruitment domain family, member 110.726
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.722
Ptpn6protein tyrosine phosphatase, non-receptor type 60.717
Egfrepidermal growth factor receptor0.716
Drd2dopamine receptor D20.715
Rag1recombination activating gene 10.710
Batfbasic leucine zipper transcription factor, ATF-like0.702
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.701
Pdcd1programmed cell death 10.691
Lhx3LIM homeobox protein 30.681
Birc3baculoviral IAP repeat-containing 30.679
Ticam1toll-like receptor adaptor molecule 10.663
H2-Aahistocompatibility 2, class II antigen A, alpha0.657
Apcadenomatosis polyposis coli0.646
FaslFas ligand (TNF superfamily, member 6)0.643
Mmp9matrix metallopeptidase 90.631
Cd22CD22 antigen0.628
Nos1nitric oxide synthase 1, neuronal0.625
Ptprcprotein tyrosine phosphatase, receptor type, C0.622
Icosinducible T-cell co-stimulator0.618
Fcgr2bFc receptor, IgG, low affinity IIb0.607
Gli3GLI-Kruppel family member GLI30.601
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.600
Il6interleukin 60.599
Cd160CD160 antigen0.596
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.595
Clec4dC-type lectin domain family 4, member d0.594
Map3k14mitogen-activated protein kinase kinase kinase 140.573
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.572
Casp8caspase 80.566
Il1r1interleukin 1 receptor, type I0.564
Esr1estrogen receptor 1 (alpha)0.564
Meox2mesenchyme homeobox 20.560
Sfpi1SFFV proviral integration 10.556
Foxn1forkhead box N10.555
Stat5bsignal transducer and activator of transcription 5B0.552
Dkk1dickkopf homolog 1 (Xenopus laevis)0.540
Il27rainterleukin 27 receptor, alpha0.535
Nck2non-catalytic region of tyrosine kinase adaptor protein 20.532
Cd96CD96 antigen0.530
Rargretinoic acid receptor, gamma0.528
Stat1signal transducer and activator of transcription 10.525
Ntf3neurotrophin 30.523
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-DaRT1 class II, locus Da0.768
RT1-BaRT1 class II, locus Ba0.688
RT1-BbRT1 class II, locus Bb0.423
Cd44Cd44 molecule0.273
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.238
RT1-Db1RT1 class II, locus Db10.235
Cd37CD37 molecule0.235
Cd247Cd247 molecule0.150
RT1-DMbRT1 class II, locus DMb0.116
RT1-DMaRT1 class II, locus DMa0.101
Cd2Cd2 molecule0.080
Il10interleukin 100.077
Ciitaclass II, major histocompatibility complex, transactivator0.074
Laptm5lysosomal protein transmembrane 50.054
Ptprcprotein tyrosine phosphatase, receptor type, C0.050
Cd53Cd53 molecule0.050
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.048
Tas2r123taste receptor, type 2, member 1230.048
Hckhemopoietic cell kinase0.046
Ptpn6protein tyrosine phosphatase, non-receptor type 60.045
Lyz2lysozyme 20.044
Cd38CD38 molecule0.044
Il1binterleukin 1 beta0.040
Aif1allograft inflammatory factor 10.040
Arhgap4Rho GTPase activating protein 40.039
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.037
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.036
Inpp5dinositol polyphosphate-5-phosphatase D0.035
Casp1caspase 10.034
Pmfbp1polyamine modulated factor 1 binding protein 10.034
Lcp2lymphocyte cytosolic protein 20.032
Anxa2annexin A20.031
Cd5Cd5 molecule0.030
Arpc1bactin related protein 2/3 complex, subunit 1B0.030
F2rl2coagulation factor II (thrombin) receptor-like 20.029
Cpceruloplasmin0.029
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.028
Ctsscathepsin S0.026
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.026
Cfpcomplement factor properdin0.026
Il1rl1interleukin 1 receptor-like 10.026
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.026
Spnsialophorin0.025
Slfn2schlafen 20.025
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.025
Ppyr1pancreatic polypeptide receptor 10.023
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.023
Il2rbinterleukin 2 receptor, beta0.023
Nr5a2nuclear receptor subfamily 5, group A, member 20.023
Ptafrplatelet-activating factor receptor0.022
Il18interleukin 180.022
Mmp10matrix metallopeptidase 100.021
Lef1lymphoid enhancer binding factor 10.021
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.021
RGD1559588similar to cell surface receptor FDFACT0.020
Plac8placenta-specific 80.020
Gzmkgranzyme K0.019
Ptger4prostaglandin E receptor 4 (subtype EP4)0.019
Itgb7integrin, beta 70.019
Itgadintegrin, alpha D0.019
Ptprqprotein tyrosine phosphatase, receptor type, Q0.018
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.018
Ccr5chemokine (C-C motif) receptor 50.017
Nkg7natural killer cell group 7 sequence0.016
Zbp1Z-DNA binding protein 10.016
Mep1ameprin 1 alpha0.016
Alox5aparachidonate 5-lipoxygenase activating protein0.016
Scn11asodium channel, voltage-gated, type XI, alpha0.016
Kcnq3potassium voltage-gated channel, KQT-like subfamily, member 30.016
Hmox1heme oxygenase (decycling) 10.016
Skap2src kinase associated phosphoprotein 20.016
Gpr114G protein-coupled receptor 1140.016
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.016
Syt8synaptotagmin VIII0.015
Cd200r1CD200 receptor 10.015
Il6interleukin 60.015
Impg2interphotoreceptor matrix proteoglycan 20.015
KlKlotho0.015
Myo1gmyosin IG0.015
Sellselectin L0.015
Jak1Janus kinase 10.015
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.015
Metmet proto-oncogene0.015
Slc12a1solute carrier family 12 (sodium/potassium/chloride transporters), member 10.015
Eregepiregulin0.015
MGC112715hypothetical protein LOC6908990.015
Kcnv1potassium channel, subfamily V, member 10.014
Rassf5Ras association (RalGDS/AF-6) domain family member 50.014
Kcng3potassium voltage-gated channel, subfamily G, member 30.014
Fgf11fibroblast growth factor 110.014
Napsanapsin A aspartic peptidase0.014
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.014
Rt1.aaMHC class I RT1.Aa alpha-chain0.014
Gfapglial fibrillary acidic protein0.014
Gpr20G protein-coupled receptor 200.014
Olr1466olfactory receptor 14660.014
C1qbcomplement component 1, q subcomponent, B chain0.014
Ccl5chemokine (C-C motif) ligand 50.013
Col10a1collagen, type X, alpha 10.013
Ncf4neutrophil cytosolic factor 40.013
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism