The network for 'embryonic camera type eye development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

embryonic camera type eye development

The process occurring during the embryonic phase whose specific outcome is the progression of the eye over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
EP300E1A binding protein p3001.000
MED25mediator complex subunit 251.000
CREBBPCREB binding protein0.999
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.993
RUNX1runt-related transcription factor 10.982
HNF4Ahepatocyte nuclear factor 4, alpha0.963
RXRAretinoid X receptor, alpha0.960
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.957
SETD8SET domain containing (lysine methyltransferase) 80.947
NCOA1nuclear receptor coactivator 10.880
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.844
BCORBCL6 corepressor0.824
HIPK2homeodomain interacting protein kinase 20.718
SP1Sp1 transcription factor0.655
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.649
PTPN11protein tyrosine phosphatase, non-receptor type 110.565
SMARCC2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 20.552
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.550
PTCH1patched 10.524
RASSF5Ras association (RalGDS/AF-6) domain family member 50.514
INSRinsulin receptor0.514
MMP14matrix metallopeptidase 14 (membrane-inserted)0.463
MECP2methyl CpG binding protein 2 (Rett syndrome)0.451
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.446
ARID2AT rich interactive domain 2 (ARID, RFX-like)0.433
FGFR1fibroblast growth factor receptor 10.412
PMLpromyelocytic leukemia0.412
ARID1BAT rich interactive domain 1B (SWI1-like)0.391
ARHGEF12Rho guanine nucleotide exchange factor (GEF) 120.378
NCOA3nuclear receptor coactivator 30.366
SMARCA2SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 20.366
ALDH2aldehyde dehydrogenase 2 family (mitochondrial)0.355
WNT3Awingless-type MMTV integration site family, member 3A0.355
DKK1dickkopf homolog 1 (Xenopus laevis)0.351
SMARCD1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 10.348
GATA2GATA binding protein 20.338
NR0B2nuclear receptor subfamily 0, group B, member 20.311
IRS1insulin receptor substrate 10.307
CATcatalase0.297
GSK3Bglycogen synthase kinase 3 beta0.283
SMARCB1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 10.280
DCAF7DDB1 and CUL4 associated factor 70.280
MDM2Mdm2 p53 binding protein homolog (mouse)0.278
SIN3ASIN3 homolog A, transcription regulator (yeast)0.273
GRB10growth factor receptor-bound protein 100.269
DYRK1Adual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A0.225
PIAS2protein inhibitor of activated STAT, 20.197
MYOD1myogenic differentiation 10.194
NCOR1nuclear receptor corepressor 10.192
HOXD12homeobox D120.191
CAV1caveolin 1, caveolae protein, 22kDa0.178
SMAD4SMAD family member 40.174
KCTD1potassium channel tetramerisation domain containing 10.173
NOGnoggin0.168
GAB1GRB2-associated binding protein 10.162
NEUROD1neurogenic differentiation 10.162
SKIv-ski sarcoma viral oncogene homolog (avian)0.157
NR5A2nuclear receptor subfamily 5, group A, member 20.147
COL2A1collagen, type II, alpha 10.146
LHX2LIM homeobox 20.143
HIC1hypermethylated in cancer 10.142
TCF12transcription factor 120.138
MPZL1myelin protein zero-like 10.137
NCOR2nuclear receptor corepressor 20.135
BBS1Bardet-Biedl syndrome 10.133
SH3BP4SH3-domain binding protein 40.132
FOXC1forkhead box C10.132
LRRK2leucine-rich repeat kinase 20.128
PDX1pancreatic and duodenal homeobox 10.122
PPARAperoxisome proliferator-activated receptor alpha0.118
RXRBretinoid X receptor, beta0.113
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.113
NKX2-2NK2 homeobox 20.112
PIAS1protein inhibitor of activated STAT, 10.111
POU3F2POU class 3 homeobox 20.110
STAT5Asignal transducer and activator of transcription 5A0.101
TCF4transcription factor 40.099
FOXF1forkhead box F10.099
FOXG1forkhead box G10.098
KAT2BK(lysine) acetyltransferase 2B0.098
POU4F2POU class 4 homeobox 20.097
LRRN2leucine rich repeat neuronal 20.093
GAB2GRB2-associated binding protein 20.092
FZD10frizzled homolog 10 (Drosophila)0.089
KANK2KN motif and ankyrin repeat domains 20.088
MNX1motor neuron and pancreas homeobox 10.083
SKILSKI-like oncogene0.083
LMO2LIM domain only 2 (rhombotin-like 1)0.082
SIX3SIX homeobox 30.081
SETD7SET domain containing (lysine methyltransferase) 70.080
SMAD3SMAD family member 30.080
SIRT1sirtuin 10.079
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.077
PHOX2Apaired-like homeobox 2a0.077
SPOPspeckle-type POZ protein0.077
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.075
POU4F1POU class 4 homeobox 10.074
ZIC1Zic family member 1 (odd-paired homolog, Drosophila)0.074
SOX1SRY (sex determining region Y)-box 10.073
HOXD13homeobox D130.073
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.996
tfap2atranscription factor AP-2 alpha0.976
gli1GLI-Kruppel family member 10.974
otx2orthodenticle homolog 20.972
bmp2bbone morphogenetic protein 2b0.971
lhx2bLIM homeobox 2b0.970
sox2SRY-box containing gene 20.964
shhasonic hedgehog a0.951
rx3retinal homeobox gene 30.936
fgf3fibroblast growth factor 30.934
lmx1b.1LIM homeobox transcription factor 1, beta 10.931
ndr2nodal-related 20.893
fgf17fibroblast growth factor 170.886
gbx2gastrulation brain homeo box 20.884
zic2azic family member 2 (odd-paired homolog, Drosophila), a0.861
dlx2adistal-less homeobox gene 2a0.861
bmp4bone morphogenetic protein 40.851
cdh2cadherin 2, neuronal0.845
wnt5bwingless-type MMTV integration site family, member 5b0.841
wnt3wingless-type MMTV integration site family, member 30.835
eya1eyes absent homolog 10.827
tcf7l2transcription factor 7-like 2 (T-cell specific, HMG-box)0.819
foxa2forkhead box A20.817
barhl2BarH-like 20.759
mab21l2mab-21-like 20.730
eng2aengrailed 2a0.716
rargaretinoic acid receptor gamma a0.699
bmp2abone morphogenetic protein 2a0.689
wnt2wingless-type MMTV integration site family member 20.688
fezf2FEZ family zinc finger 20.681
isl1islet10.668
chdchordin0.664
wnt11wingless-type MMTV integration site family, member 110.651
wnt10awingless-type MMTV integration site family, member 10a0.641
irx1airoquois homeobox protein 1, a0.630
flhfloating head0.625
znf503zinc finger protein 5030.621
pax2apaired box gene 2a0.602
wnt3awingless-type MMTV integration site family, member 3A0.582
foxn4forkhead box N40.551
hnf1baHNF1 homeobox Ba0.511
dkk1bdickkopf 1b0.508
fgf8bfibroblast growth factor 8 b0.502
fgf10afibroblast growth factor 10a0.502
fgf8afibroblast growth factor 8 a0.495
sox32SRY-box containing gene 320.486
dlx4adistal-less homeobox gene 4a0.460
six3bsine oculis homeobox homolog 3b0.452
gli2aGLI-Kruppel family member GLI2a0.449
zic1zic family member 1 (odd-paired homolog, Drosophila)0.403
notch2notch homolog 20.400
spry2sprouty homolog 20.395
ascl1aachaete-scute complex-like 1a (Drosophila)0.392
atoh7atonal homolog 70.376
dharmadharma0.368
foxd3forkhead box D30.360
zic3zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila)0.358
nrxn2aneurexin 2a0.342
vsx1visual system homeobox 1 homolog, chx10-like0.342
sfrp1asecreted frizzled-related protein 1a0.330
ptch1patched 10.327
lhx6LIM homeobox 60.327
vax1ventral anterior homeobox 10.316
map2k4amitogen-activated protein kinase kinase 4a0.311
restRE1-silencing transcription factor0.301
vax2ventral anterior homeobox 20.300
wnt8bwingless-type MMTV integration site family, member 8b0.299
ephb3aeph receptor B3a0.299
fgfr1bfibroblast growth factor receptor 1b0.299
tcf7transcription factor 7 (T-cell specific, HMG-box)0.295
osr1odd-skipped related 1 (Drosophila)0.283
nkx3.2NK3 homeobox 20.273
loxlysyl oxidase0.273
fzd5frizzled homolog 50.270
pax6bpaired box gene 6b0.269
six2asine oculis-related homeobox 2a0.268
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.266
dlx4bdistal-less homeobox gene 4b0.265
runx3runt-related transcription factor 30.262
nkx1.2laNK1 transcription factor related 2-like,a0.258
tgfb2transforming growth factor, beta 20.255
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.254
fzd7afrizzled homolog 7a0.250
pitx3paired-like homeodomain transcription factor 30.247
tbx16T-box gene 160.243
spry1sprouty homolog 1 (Drosophila)0.238
foxc1aforkhead box C1a0.237
lhx1bLIM homeobox 1b0.235
rx2retinal homeobox gene 20.230
gbx1gastrulation brain homeobox 10.229
hmx4H6 family homeobox 40.228
foxp2forkhead box P20.225
fgf20afibroblast growth factor 20a0.221
lamb1alaminin, beta 1a0.219
msxemuscle segment homeobox E0.218
foxg1aforkhead box G1a0.214
fgf4fibroblast growth factor 40.214
her5hairy-related 50.210
foxd5forkhead box D50.202
hmx3homeo box (H6 family) 30.201
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Shhsonic hedgehog1.000
Gli3GLI-Kruppel family member GLI30.999
Fgfr2fibroblast growth factor receptor 20.997
Hand1heart and neural crest derivatives expressed transcript 10.996
Pax3paired box gene 30.996
Bmp4bone morphogenetic protein 40.996
Pitx2paired-like homeodomain transcription factor 20.995
Prrx1paired related homeobox 10.994
Tbx1T-box 10.992
Tbx3T-box 30.992
Bmp7bone morphogenetic protein 70.990
Hand2heart and neural crest derivatives expressed transcript 20.990
Foxc1forkhead box C10.986
Pax2paired box gene 20.983
Fgf8fibroblast growth factor 80.982
Ror2receptor tyrosine kinase-like orphan receptor 20.978
Msx1homeobox, msh-like 10.978
Rarbretinoic acid receptor, beta0.973
Otx2orthodenticle homolog 2 (Drosophila)0.965
Rargretinoic acid receptor, gamma0.958
Eya1eyes absent 1 homolog (Drosophila)0.951
Tcfap2atranscription factor AP-2, alpha0.949
Runx2runt related transcription factor 20.942
Sox2SRY-box containing gene 20.938
Foxc2forkhead box C20.931
Msx2homeobox, msh-like 20.917
Fgfr1fibroblast growth factor receptor 10.910
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.903
Zeb1zinc finger E-box binding homeobox 10.862
Pitx1paired-like homeodomain transcription factor 10.838
Rspo2R-spondin 2 homolog (Xenopus laevis)0.815
Tgfb2transforming growth factor, beta 20.785
Wnt5awingless-related MMTV integration site 5A0.783
Pax6paired box gene 60.748
Pbx1pre B-cell leukemia transcription factor 10.741
Gli2GLI-Kruppel family member GLI20.729
Sox11SRY-box containing gene 110.703
Gscgoosecoid homeobox0.703
Prrx2paired related homeobox 20.700
Tbx15T-box 150.694
Lhx1LIM homeobox protein 10.665
Nognoggin0.646
Hoxa13homeobox A130.643
Smosmoothened homolog (Drosophila)0.642
Smad6MAD homolog 6 (Drosophila)0.633
Gbx2gastrulation brain homeobox 20.626
Gas1growth arrest specific 10.619
Acvr1activin A receptor, type 10.597
Nodalnodal0.588
Pax8paired box gene 80.587
Dlx5distal-less homeobox 50.566
Vangl2vang-like 2 (van gogh, Drosophila)0.555
Hoxa1homeobox A10.544
Bmp5bone morphogenetic protein 50.543
Fgf10fibroblast growth factor 100.542
Lrp6low density lipoprotein receptor-related protein 60.528
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.482
Pou5f1POU domain, class 5, transcription factor 10.468
Col2a1collagen, type II, alpha 10.465
Isl1ISL1 transcription factor, LIM/homeodomain0.465
Drd2dopamine receptor D20.455
Alx4aristaless-like homeobox 40.447
Zic3zinc finger protein of the cerebellum 30.439
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.412
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.395
Chrdchordin0.389
Jag1jagged 10.385
Gpc3glypican 30.383
Lrp2low density lipoprotein receptor-related protein 20.366
Chd7chromodomain helicase DNA binding protein 70.358
Foxh1forkhead box H10.353
Gdf5growth differentiation factor 50.352
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.342
Tcf21transcription factor 210.335
Wnt3awingless-related MMTV integration site 3A0.332
Rnf2ring finger protein 20.327
Twist2twist homolog 2 (Drosophila)0.326
Dkk1dickkopf homolog 1 (Xenopus laevis)0.313
Ptk7PTK7 protein tyrosine kinase 70.307
Retret proto-oncogene0.285
Hoxa11homeobox A110.284
Fzd8frizzled homolog 8 (Drosophila)0.284
Efna2ephrin A20.282
Sall4sal-like 4 (Drosophila)0.272
Gata4GATA binding protein 40.256
Dok1docking protein 10.254
Ntf3neurotrophin 30.240
Hoxd11homeobox D110.236
Gja3gap junction protein, alpha 30.232
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.232
Tcfap2ctranscription factor AP-2, gamma0.226
Bmpr1abone morphogenetic protein receptor, type 1A0.225
Ednraendothelin receptor type A0.215
Hoxb3homeobox B30.208
Grb10growth factor receptor bound protein 100.208
Pou3f3POU domain, class 3, transcription factor 30.204
Alx3aristaless-like homeobox 30.199
Bmp2bone morphogenetic protein 20.197
Ece1endothelin converting enzyme 10.193
Tcf7l1transcription factor 7-like 1 (T-cell specific, HMG box)0.193
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism