The network for 'positive regulation of protein polyubiquitination' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of protein polyubiquitination

Any process that activates or increases the frequency, rate or extent of protein polyubiquitination.

NameDescriptionProbabilityFunc Analog Organism
BIRC2baculoviral IAP repeat containing 20.944
BIRC3baculoviral IAP repeat containing 30.546
RIPK2receptor-interacting serine-threonine kinase 20.544
XIAPX-linked inhibitor of apoptosis0.438
TRAF3TNF receptor-associated factor 30.262
ZNRF1zinc and ring finger 10.204
RNF11ring finger protein 110.169
TRAF1TNF receptor-associated factor 10.168
UBE2V1ubiquitin-conjugating enzyme E2 variant 10.107
CDK2cyclin-dependent kinase 20.105
CASP9caspase 9, apoptosis-related cysteine peptidase0.104
CASP3caspase 3, apoptosis-related cysteine peptidase0.094
UBE2D3ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)0.084
RIPK1receptor (TNFRSF)-interacting serine-threonine kinase 10.075
ZNF746zinc finger protein 7460.071
UBE2D1ubiquitin-conjugating enzyme E2D 1 (UBC4/5 homolog, yeast)0.036
TRAF2TNF receptor-associated factor 20.033
SKP1S-phase kinase-associated protein 10.032
APAF1apoptotic peptidase activating factor 10.026
DIABLOdiablo, IAP-binding mitochondrial protein0.020
RBX1ring-box 1, E3 ubiquitin protein ligase0.019
TANKTRAF family member-associated NFKB activator0.019
TRAF6TNF receptor-associated factor 60.019
CASP7caspase 7, apoptosis-related cysteine peptidase0.016
TRIM39tripartite motif containing 390.015
RIPK3receptor-interacting serine-threonine kinase 30.014
CKS1BCDC28 protein kinase regulatory subunit 1B0.014
RIPK4receptor-interacting serine-threonine kinase 40.012
RNF111ring finger protein 1110.012
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism