The network for 'lateral mesoderm development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

lateral mesoderm development

The process whose specific outcome is the progression of the lateral mesoderm over time, from its formation to the mature structure.

NameDescriptionProbabilityFunc Analog Organism
SMAD2SMAD family member 20.994
SMAD3SMAD family member 30.993
SMAD1SMAD family member 10.988
SMAD7SMAD family member 70.974
SMURF2SMAD specific E3 ubiquitin protein ligase 20.929
SMAD5SMAD family member 50.903
FGF1fibroblast growth factor 1 (acidic)0.881
BMP2bone morphogenetic protein 20.800
NOTCH1notch 10.554
FGF10fibroblast growth factor 100.394
RUNX1runt-related transcription factor 10.361
GATA2GATA binding protein 20.343
SMURF1SMAD specific E3 ubiquitin protein ligase 10.306
NCOR1nuclear receptor corepressor 10.213
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.209
SKILSKI-like oncogene0.195
ATXN1Lataxin 1-like0.125
SMAD6SMAD family member 60.099
MAML1mastermind-like 1 (Drosophila)0.081
NEDD4neural precursor cell expressed, developmentally down-regulated 40.079
PTPN14protein tyrosine phosphatase, non-receptor type 140.077
TRAF4TNF receptor-associated factor 40.076
EP300E1A binding protein p3000.066
FGF2fibroblast growth factor 2 (basic)0.066
FBXL15F-box and leucine-rich repeat protein 150.058
SMAD4SMAD family member 40.050
CXXC5CXXC finger protein 50.050
SKIv-ski sarcoma viral oncogene homolog (avian)0.048
NCOR2nuclear receptor corepressor 20.047
SPENspen homolog, transcriptional regulator (Drosophila)0.046
FGF7fibroblast growth factor 70.045
NOTCH2notch 20.044
NOTCH3notch 30.043
YY1YY1 transcription factor0.042
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.041
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.040
JAG1jagged 10.039
AMOTL1angiomotin like 10.039
HIPK2homeodomain interacting protein kinase 20.038
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.037
SPG20spastic paraplegia 20 (Troyer syndrome)0.036
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.033
AMOTL2angiomotin like 20.033
ZHX1zinc fingers and homeoboxes 10.032
SOX7SRY (sex determining region Y)-box 70.030
NLKnemo-like kinase0.029
SMAD9SMAD family member 90.029
GATA1GATA binding protein 1 (globin transcription factor 1)0.028
FGFR3fibroblast growth factor receptor 30.027
RPS6KA5ribosomal protein S6 kinase, 90kDa, polypeptide 50.026
TGFBR1transforming growth factor, beta receptor 10.024
TCF12transcription factor 120.024
RNF11ring finger protein 110.022
MKL2MKL/myocardin-like 20.022
WHSC1L1Wolf-Hirschhorn syndrome candidate 1-like 10.022
FRS2fibroblast growth factor receptor substrate 20.019
DCP1ADCP1 decapping enzyme homolog A (S. cerevisiae)0.019
SEPT1septin 10.019
TFPI2tissue factor pathway inhibitor 20.018
BMP4bone morphogenetic protein 40.018
HNF4Ahepatocyte nuclear factor 4, alpha0.018
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.017
CIR1corepressor interacting with RBPJ, 10.017
SREBF2sterol regulatory element binding transcription factor 20.017
ACBD3acyl-CoA binding domain containing 30.016
HOXC8homeobox C80.015
NEDD9neural precursor cell expressed, developmentally down-regulated 90.015
SORBS3sorbin and SH3 domain containing 30.015
GMEB1glucocorticoid modulatory element binding protein 10.014
YAP1Yes-associated protein 10.014
DCP1BDCP1 decapping enzyme homolog B (S. cerevisiae)0.014
SRFserum response factor (c-fos serum response element-binding transcription factor)0.013
VPS24vacuolar protein sorting 24 homolog (S. cerevisiae)0.013
ING2inhibitor of growth family, member 20.013
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.012
NOSTRINnitric oxide synthase trafficker0.012
CDK6cyclin-dependent kinase 60.012
ITGB1BP2integrin beta 1 binding protein (melusin) 20.012
DACH1dachshund homolog 1 (Drosophila)0.012
TP53BP2tumor protein p53 binding protein, 20.011
ELF4E74-like factor 4 (ets domain transcription factor)0.011
ZNF576zinc finger protein 5760.011
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.011
MAST4microtubule associated serine/threonine kinase family member 40.011
FOXF2forkhead box F20.010
FOXO3forkhead box O30.010
DAZAP2DAZ associated protein 20.010
ZBED5zinc finger, BED-type containing 50.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
tbx1T-box 10.785
fgf8afibroblast growth factor 8 a0.763
tbx16T-box gene 160.744
chdchordin0.744
pax2apaired box gene 2a0.735
wnt5bwingless-type MMTV integration site family, member 5b0.633
dlddeltaD0.557
ntlano tail a0.472
bmp2bbone morphogenetic protein 2b0.424
ndr2nodal-related 20.397
gli2aGLI-Kruppel family member GLI2a0.297
atoh1batonal homolog 1b0.285
lft1lefty10.210
eve1even-skipped-like10.207
cdh2cadherin 2, neuronal0.180
tbx2bT-box 2b0.157
pdlim3bPDZ and LIM domain 3b0.148
ccm2cerebral cavernous malformation 20.132
wnt11wingless-type MMTV integration site family, member 110.118
her7hairy and enhancer of split related-70.113
flhfloating head0.109
rxraaretinoid X receptor, alpha a0.107
gli1GLI-Kruppel family member 10.105
gro1groucho 10.101
tbx2aT-box gene 2a0.100
nkx2.5NK2 transcription factor related 50.095
mibmind bomb0.094
sox32SRY-box containing gene 320.090
etv5bets variant 5b0.089
her1hairy-related 10.084
LOC100000687signal peptide, CUB and EGF-like domain-containing protein 3-like0.083
aldh1a2aldehyde dehydrogenase 1 family, member A20.081
isl1islet10.078
shhasonic hedgehog a0.078
slc25a37solute carrier family 25, member 370.077
fbn2bfibrillin 2b0.071
bmpr2abone morphogenetic protein receptor, type II a (serine/threonine kinase)0.071
spawsouthpaw0.070
foxg1aforkhead box G1a0.069
neo1neogenin 10.068
cdx4caudal type homeo box transcription factor 40.068
fn1fibronectin 10.068
raraaretinoic acid receptor, alpha a0.066
mespbmesoderm posterior b0.065
dladeltaA0.063
epha4aeph receptor A4a0.060
twist1btwist1b0.057
mespamesoderm posterior a0.057
otpborthopedia homolog b0.057
spns2spinster homolog 2 (Drosophila)0.056
vcanbversican b0.056
ripply1ripply10.053
fzd10frizzled homolog 100.053
gbx2gastrulation brain homeo box 20.051
hmgcrb3-hydroxy-3-methylglutaryl-Coenzyme A reductase b0.051
lfnglunatic fringe homolog0.051
ptf1apancreas specific transcription factor, 1a0.048
bhlhe40basic helix-loop-helix family, member e400.047
oepone-eyed pinhead0.046
nr2f5nuclear receptor subfamily 2, group F, member 50.044
twist1atwist1a0.044
lhx1aLIM homeobox 1a0.043
h1mlinker histone H1M0.042
tbx24T-box 240.042
smad1MAD homolog 1 (Drosophila)0.042
eng2bengrailed 2b0.041
ascl1aachaete-scute complex-like 1a (Drosophila)0.039
mmp2matrix metalloproteinase 20.039
nkd1naked cuticle homolog 1 (Drosophila)0.039
plcg1phospholipase C, gamma 10.039
pard6gbpar-6 partitioning defective 6 homolog gamma B (C. elegans)0.038
neurog1neurogenin 10.038
bmpr2bbone morphogenetic protein receptor, type II b (serine/threonine kinase)0.037
bmp4bone morphogenetic protein 40.036
sema3aasemaphorin 3aa0.035
gdf11growth differentiation factor 110.035
myf5myogenic factor 50.034
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.034
wu:fv91b12wu:fv91b120.034
dlcdeltaC0.034
rxrabretinoid x receptor, alpha b0.034
msgn1mesogenin 10.034
gata5GATA-binding protein 50.034
pax6apaired box gene 6a0.034
fgfr2fibroblast growth factor receptor 20.033
runx1runt-related transcription factor 10.033
cxcl12bchemokine (C-X-C motif) ligand 12b (stromal cell-derived factor 1)0.033
rxrgbretinoid X receptor, gamma b0.033
tnnt2atroponin T2a, cardiac0.033
six3bsine oculis homeobox homolog 3b0.032
rx3retinal homeobox gene 30.032
sox17SRY-box containing gene 170.032
nkx2.1aNK2 homeobox 1a0.031
her11hairy-related 110.031
vcanaversican a0.030
evx1even-skipped homeobox 10.030
gro2groucho 20.030
has2hyaluronan synthase 20.030
nr1d2bnuclear receptor subfamily 1, group D, member 2b0.030
fynaFYN oncogene related to SRC, FGR, YES a0.029
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Bmp4bone morphogenetic protein 40.970
Pitx2paired-like homeodomain transcription factor 20.962
Nodalnodal0.955
Yap1yes-associated protein 10.932
Foxc1forkhead box C10.854
Fgfr1fibroblast growth factor receptor 10.835
Shhsonic hedgehog0.788
Foxh1forkhead box H10.631
Bmpr1abone morphogenetic protein receptor, type 1A0.455
Vangl2vang-like 2 (van gogh, Drosophila)0.442
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.361
Gli3GLI-Kruppel family member GLI30.353
Smad3MAD homolog 3 (Drosophila)0.341
Pax2paired box gene 20.338
Sox9SRY-box containing gene 90.316
Bmp7bone morphogenetic protein 70.279
Gata4GATA binding protein 40.258
Dnahc11dynein, axonemal, heavy chain 110.255
Fgf8fibroblast growth factor 80.252
Smosmoothened homolog (Drosophila)0.239
Notch1Notch gene homolog 1 (Drosophila)0.230
Fgfr2fibroblast growth factor receptor 20.224
Msx2homeobox, msh-like 20.223
Ror2receptor tyrosine kinase-like orphan receptor 20.220
Kif3akinesin family member 3A0.213
Ctnnb1catenin (cadherin associated protein), beta 10.209
Smad4MAD homolog 4 (Drosophila)0.202
Tbx6T-box 60.202
Apcadenomatosis polyposis coli0.193
Foxc2forkhead box C20.142
Acvr1activin A receptor, type 10.121
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.109
Gli2GLI-Kruppel family member GLI20.106
Psen1presenilin 10.094
Fgf9fibroblast growth factor 90.092
Gdf5growth differentiation factor 50.092
Jag1jagged 10.090
Hoxd13homeobox D130.086
Foxf1aforkhead box F1a0.081
Tgfbr2transforming growth factor, beta receptor II0.075
Gscgoosecoid homeobox0.071
Amhr2anti-Mullerian hormone type 2 receptor0.070
Lhx1LIM homeobox protein 10.067
Smad6MAD homolog 6 (Drosophila)0.066
Fgfr3fibroblast growth factor receptor 30.064
Tead2TEA domain family member 20.063
LfngLFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.061
Zic3zinc finger protein of the cerebellum 30.061
Col2a1collagen, type II, alpha 10.061
Tgfb2transforming growth factor, beta 20.055
Gpc3glypican 30.054
Notch2Notch gene homolog 2 (Drosophila)0.054
Phexphosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)0.051
Hand2heart and neural crest derivatives expressed transcript 20.050
Tgfbr1transforming growth factor, beta receptor I0.049
Hand1heart and neural crest derivatives expressed transcript 10.046
Ptpn14protein tyrosine phosphatase, non-receptor type 140.044
Wwtr1WW domain containing transcription regulator 10.040
Rargretinoic acid receptor, gamma0.039
Hoxa3homeobox A30.039
Ptk7PTK7 protein tyrosine kinase 70.039
Sox7SRY-box containing gene 70.038
Sall4sal-like 4 (Drosophila)0.038
Vegfavascular endothelial growth factor A0.037
Lrp6low density lipoprotein receptor-related protein 60.037
Zeb1zinc finger E-box binding homeobox 10.036
Dll1delta-like 1 (Drosophila)0.034
Pcsk5proprotein convertase subtilisin/kexin type 50.034
Chrdchordin0.034
Hoxb3homeobox B30.033
Tead1TEA domain family member 10.032
Esr2estrogen receptor 2 (beta)0.032
Hes1hairy and enhancer of split 1 (Drosophila)0.029
Dnahc5dynein, axonemal, heavy chain 50.027
Pax1paired box gene 10.027
Prrx2paired related homeobox 20.026
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.026
Meox2mesenchyme homeobox 20.026
Otx2orthodenticle homolog 2 (Drosophila)0.026
Gdf9growth differentiation factor 90.025
Cfc1cripto, FRL-1, cryptic family 10.025
Gdf3growth differentiation factor 30.025
Ptch1patched homolog 10.024
Gdf1growth differentiation factor 10.024
Nkx3-2NK3 homeobox 20.023
Ptenphosphatase and tensin homolog0.022
Six2sine oculis-related homeobox 2 homolog (Drosophila)0.022
Rarbretinoic acid receptor, beta0.022
Fmn1formin 10.022
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.021
Dkk1dickkopf homolog 1 (Xenopus laevis)0.021
Inhbainhibin beta-A0.021
Tead4TEA domain family member 40.020
Hoxa1homeobox A10.020
Bmp5bone morphogenetic protein 50.019
Npr2natriuretic peptide receptor 20.019
Foxj1forkhead box J10.018
Nognoggin0.018
Tgfbr3transforming growth factor, beta receptor III0.018
Ntf3neurotrophin 30.018
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism