The network for 'mammary gland morphogenesis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

mammary gland morphogenesis

The process in which anatomical structures of the mammary gland are generated and organized. Morphogenesis refers to the creation of shape. The mammary gland is a large compound sebaceous gland that in female mammals is modified to secrete milk.

NameDescriptionProbabilityFunc Analog Organism
RARAretinoic acid receptor, alpha0.986
FGFR2fibroblast growth factor receptor 20.982
EGFRepidermal growth factor receptor0.890
PTPN1protein tyrosine phosphatase, non-receptor type 10.890
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.861
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.824
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.816
NCOA1nuclear receptor coactivator 10.764
CREBBPCREB binding protein0.710
FGFR1fibroblast growth factor receptor 10.621
NCOA2nuclear receptor coactivator 20.581
FGF10fibroblast growth factor 100.549
MEOX2mesenchyme homeobox 20.433
FGF1fibroblast growth factor 1 (acidic)0.416
EHFets homologous factor0.413
NCOR2nuclear receptor corepressor 20.374
S100A4S100 calcium binding protein A40.372
IL4Rinterleukin 4 receptor0.362
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.285
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.269
HRhairless homolog (mouse)0.265
CAV1caveolin 1, caveolae protein, 22kDa0.259
SOX10SRY (sex determining region Y)-box 100.216
FSTL1follistatin-like 10.194
JAK1Janus kinase 10.188
TGFB3transforming growth factor, beta 30.177
TGFB1transforming growth factor, beta 10.174
EP300E1A binding protein p3000.172
RXRAretinoid X receptor, alpha0.169
S100A2S100 calcium binding protein A20.153
TM4SF1transmembrane 4 L six family member 10.146
POU3F2POU class 3 homeobox 20.134
ESR1estrogen receptor 10.132
CUEDC2CUE domain containing 20.130
JDP2Jun dimerization protein 20.129
FGF7fibroblast growth factor 70.113
BCL2L1BCL2-like 10.113
GSK3Bglycogen synthase kinase 3 beta0.111
DAXXdeath-domain associated protein0.104
PHLPP1PH domain and leucine rich repeat protein phosphatase 10.086
NCK2NCK adaptor protein 20.083
BAK1BCL2-antagonist/killer 10.079
FHL2four and a half LIM domains 20.077
CCND1cyclin D10.077
CCND3cyclin D30.077
CDK6cyclin-dependent kinase 60.075
HIPK2homeodomain interacting protein kinase 20.075
DKK1dickkopf homolog 1 (Xenopus laevis)0.071
KAT2BK(lysine) acetyltransferase 2B0.068
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.067
FBXW11F-box and WD repeat domain containing 110.067
ESR2estrogen receptor 2 (ER beta)0.066
NR4A1nuclear receptor subfamily 4, group A, member 10.064
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.062
IGF1Rinsulin-like growth factor 1 receptor0.060
MSX1msh homeobox 10.057
CAPRIN2caprin family member 20.055
ZFYVE9zinc finger, FYVE domain containing 90.054
DCCdeleted in colorectal carcinoma0.054
FGF8fibroblast growth factor 8 (androgen-induced)0.054
RUNX1runt-related transcription factor 10.053
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.052
DDX17DEAD (Asp-Glu-Ala-Asp) box polypeptide 170.049
BCL3B-cell CLL/lymphoma 30.046
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.046
FZD1frizzled homolog 1 (Drosophila)0.045
TRIP6thyroid hormone receptor interactor 60.045
FRS2fibroblast growth factor receptor substrate 20.045
BIKBCL2-interacting killer (apoptosis-inducing)0.045
FGFR3fibroblast growth factor receptor 30.045
RUNX1T1runt-related transcription factor 1; translocated to, 1 (cyclin D-related)0.044
CAV2caveolin 20.044
GHRgrowth hormone receptor0.043
TGFB2transforming growth factor, beta 20.042
GRIP1glutamate receptor interacting protein 10.042
SMAD2SMAD family member 20.042
APCadenomatous polyposis coli0.042
DDR2discoidin domain receptor tyrosine kinase 20.041
STAT5Asignal transducer and activator of transcription 5A0.041
CRKLv-crk sarcoma virus CT10 oncogene homolog (avian)-like0.040
TGFBR1transforming growth factor, beta receptor 10.039
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.039
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.038
PTPRFprotein tyrosine phosphatase, receptor type, F0.037
STK36serine/threonine kinase 360.036
FGF3fibroblast growth factor 30.036
WNT3Awingless-type MMTV integration site family, member 3A0.036
SP1Sp1 transcription factor0.035
TRRAPtransformation/transcription domain-associated protein0.035
SNAPINSNAP-associated protein0.034
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 60.032
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)0.032
BMP2bone morphogenetic protein 20.031
IMPDH2IMP (inosine 5'-monophosphate) dehydrogenase 20.031
SUFUsuppressor of fused homolog (Drosophila)0.031
PTGISprostaglandin I2 (prostacyclin) synthase0.030
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Fgfr2fibroblast growth factor receptor 21.000
Tbx1T-box 10.999
Shhsonic hedgehog0.995
Bmp4bone morphogenetic protein 40.993
Apcadenomatosis polyposis coli0.991
Gli2GLI-Kruppel family member GLI20.990
Fgfr1fibroblast growth factor receptor 10.985
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.983
Sox9SRY-box containing gene 90.983
Tbx3T-box 30.981
Fgf10fibroblast growth factor 100.973
Pax2paired box gene 20.969
Pax3paired box gene 30.968
Fgfr3fibroblast growth factor receptor 30.968
Bcl2B-cell leukemia/lymphoma 20.967
Prrx2paired related homeobox 20.966
Trp53transformation related protein 530.965
Smad3MAD homolog 3 (Drosophila)0.959
Foxc1forkhead box C10.957
Tgfbr2transforming growth factor, beta receptor II0.957
Smad4MAD homolog 4 (Drosophila)0.941
Rararetinoic acid receptor, alpha0.927
Pitx2paired-like homeodomain transcription factor 20.919
Rxraretinoid X receptor alpha0.917
Ctnnb1catenin (cadherin associated protein), beta 10.916
Prrx1paired related homeobox 10.913
Pitx1paired-like homeodomain transcription factor 10.911
Pax8paired box gene 80.911
Rargretinoic acid receptor, gamma0.895
Robo1roundabout homolog 1 (Drosophila)0.891
Ptenphosphatase and tensin homolog0.889
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.880
Fgf8fibroblast growth factor 80.874
Ptpn11protein tyrosine phosphatase, non-receptor type 110.860
Zeb1zinc finger E-box binding homeobox 10.852
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.831
Dlx5distal-less homeobox 50.814
Bmp7bone morphogenetic protein 70.806
Foxn1forkhead box N10.802
Hand2heart and neural crest derivatives expressed transcript 20.753
Hoxa1homeobox A10.748
Slit2slit homolog 2 (Drosophila)0.740
Acvr1activin A receptor, type 10.739
Efnb2ephrin B20.738
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.732
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.732
Otx2orthodenticle homolog 2 (Drosophila)0.725
Csf1colony stimulating factor 1 (macrophage)0.722
Leprleptin receptor0.716
Foxc2forkhead box C20.705
Hand1heart and neural crest derivatives expressed transcript 10.699
Gli3GLI-Kruppel family member GLI30.696
Hmx3H6 homeobox 30.695
Ptch1patched homolog 10.685
Stat5bsignal transducer and activator of transcription 5B0.667
Ror2receptor tyrosine kinase-like orphan receptor 20.663
Dicer1Dicer1, Dcr-1 homolog (Drosophila)0.653
Tgfb1transforming growth factor, beta 10.622
Alx4aristaless-like homeobox 40.621
Jag1jagged 10.592
Smosmoothened homolog (Drosophila)0.589
Egfrepidermal growth factor receptor0.585
Pax9paired box gene 90.581
Wnt3awingless-related MMTV integration site 3A0.556
Tgfb2transforming growth factor, beta 20.551
Slit3slit homolog 3 (Drosophila)0.551
Runx2runt related transcription factor 20.545
Eya1eyes absent 1 homolog (Drosophila)0.529
Hoxa2homeobox A20.505
Vangl2vang-like 2 (van gogh, Drosophila)0.485
Myod1myogenic differentiation 10.482
CebpaCCAAT/enhancer binding protein (C/EBP), alpha0.478
Ror1receptor tyrosine kinase-like orphan receptor 10.477
Gdnfglial cell line derived neurotrophic factor0.471
Ren1renin 1 structural0.468
Retret proto-oncogene0.468
Smad6MAD homolog 6 (Drosophila)0.458
Gli1GLI-Kruppel family member GLI10.456
Lhx3LIM homeobox protein 30.456
Gata4GATA binding protein 40.448
Dkk1dickkopf homolog 1 (Xenopus laevis)0.446
Gata6GATA binding protein 60.436
Col4a3collagen, type IV, alpha 30.429
Tcfap2atranscription factor AP-2, alpha0.429
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.428
Lifleukemia inhibitory factor0.426
Vdrvitamin D receptor0.397
Barx1BarH-like homeobox 10.391
Hoxa13homeobox A130.388
Bdnfbrain derived neurotrophic factor0.387
Nf1neurofibromatosis 10.375
Tgfatransforming growth factor alpha0.366
Nr5a1nuclear receptor subfamily 5, group A, member 10.362
Ncoa3nuclear receptor coactivator 30.360
Tbx2T-box 20.358
Stat5asignal transducer and activator of transcription 5A0.356
Axin1axin 10.354
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Rararetinoic acid receptor, alpha0.314
Bmp7bone morphogenetic protein 70.047
Capn5calpain 50.045
Ddr1discoidin domain receptor tyrosine kinase 10.042
Vom2r44vomeronasal 2 receptor 440.036
Prrx1paired related homeobox 10.028
Smad3SMAD family member 30.028
Metmet proto-oncogene0.027
Itpkbinositol 1,4,5-trisphosphate 3-kinase B0.027
Ctf1cardiotrophin 10.025
Eif2ak2eukaryotic translation initiation factor 2-alpha kinase 20.022
Rargretinoic acid receptor, gamma0.022
Fat2FAT tumor suppressor homolog 2 (Drosophila)0.022
Gata3GATA binding protein 30.021
Socs3suppressor of cytokine signaling 30.020
Fgf14fibroblast growth factor 140.019
Ptpn14protein tyrosine phosphatase, non-receptor type 140.018
Rab3il1RAB3A interacting protein (rabin3)-like 10.018
Ucp2uncoupling protein 2 (mitochondrial, proton carrier)0.018
Hoxc4homeo box C40.017
Bak1BCL2-antagonist/killer 10.016
Itpr2inositol 1,4,5-triphosphate receptor, type 20.016
Pgrprogesterone receptor0.016
Col4a5collagen, type IV, alpha 50.015
Sox4SRY (sex determining region Y)-box 40.014
Golim4golgi integral membrane protein 40.014
Fbln5fibulin 50.014
Stxbp2syntaxin binding protein 20.014
Ralgdsral guanine nucleotide dissociation stimulator0.014
Pdzk1ip1PDZK1 interacting protein 10.014
Dchs1dachsous 1 (Drosophila)0.013
Slco2a1solute carrier organic anion transporter family, member 2a10.013
Mmp23matrix metallopeptidase 230.013
Sod3superoxide dismutase 3, extracellular0.013
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.012
Ccdc3coiled-coil domain containing 30.012
Bcl2B-cell CLL/lymphoma 20.012
KitlgKIT ligand0.012
Myo1dmyosin ID0.012
Shox2short stature homeobox 20.011
Erbb3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.011
Tmem79transmembrane protein 790.011
Cadcarbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase0.010
Ceacam1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.010
Capn1calpain 10.010
Nr2f6nuclear receptor subfamily 2, group F, member 60.010
Plcg2phospholipase C, gamma 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism