The network for 'leukocyte proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

leukocyte proliferation

The expansion of a leukocyte population by cell division.

NameDescriptionProbabilityFunc Analog Organism
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.997
GRB2growth factor receptor-bound protein 20.996
SYKspleen tyrosine kinase0.996
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.990
CD74CD74 molecule, major histocompatibility complex, class II invariant chain0.976
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.969
ICAM1intercellular adhesion molecule 10.937
BCL2L1BCL2-like 10.915
LATlinker for activation of T cells0.908
HLA-Fmajor histocompatibility complex, class I, F0.886
FGFR2fibroblast growth factor receptor 20.884
ZAP70zeta-chain (TCR) associated protein kinase 70kDa0.867
CD86CD86 molecule0.837
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.826
IL2RGinterleukin 2 receptor, gamma0.797
SOCS3suppressor of cytokine signaling 30.788
HLA-Bmajor histocompatibility complex, class I, B0.779
LCKlymphocyte-specific protein tyrosine kinase0.777
VAV1vav 1 guanine nucleotide exchange factor0.774
HLA-DMAmajor histocompatibility complex, class II, DM alpha0.767
BIRC3baculoviral IAP repeat containing 30.758
IL1R1interleukin 1 receptor, type I0.751
CD80CD80 molecule0.739
BCL2B-cell CLL/lymphoma 20.724
HLA-DRAmajor histocompatibility complex, class II, DR alpha0.711
TRAF6TNF receptor-associated factor 60.688
MYD88myeloid differentiation primary response gene (88)0.670
PTPN1protein tyrosine phosphatase, non-receptor type 10.662
HLA-DRB1major histocompatibility complex, class II, DR beta 1 and major histocompatibility complex, class II, DR beta 10.621
PLCG1phospholipase C, gamma 10.615
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.614
INSRinsulin receptor0.613
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)0.608
HLA-Amajor histocompatibility complex, class I, A0.608
HLA-Gmajor histocompatibility complex, class I, G0.593
HLA-DPA1major histocompatibility complex, class II, DP alpha 10.577
BTN3A2butyrophilin, subfamily 3, member A20.573
IL1Binterleukin 1, beta0.570
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.527
HLA-Cmajor histocompatibility complex, class I, C0.513
SHC1SHC (Src homology 2 domain containing) transforming protein 10.505
RUNX1runt-related transcription factor 10.497
PSEN1presenilin 10.494
FGFR1fibroblast growth factor receptor 10.480
TFF1trefoil factor 10.476
BTN3A3butyrophilin, subfamily 3, member A30.474
SOS1son of sevenless homolog 1 (Drosophila)0.466
CD247CD247 molecule0.465
CCR5chemokine (C-C motif) receptor 50.457
STAT3signal transducer and activator of transcription 3 (acute-phase response factor)0.446
HLA-Emajor histocompatibility complex, class I, E0.446
CXCL9chemokine (C-X-C motif) ligand 90.445
TICAM2toll-like receptor adaptor molecule 20.433
CCR7chemokine (C-C motif) receptor 70.430
LILRB2leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 20.429
CCR2chemokine (C-C motif) receptor 20.427
PTPN6protein tyrosine phosphatase, non-receptor type 60.427
ABI1abl-interactor 10.426
IRAK1interleukin-1 receptor-associated kinase 10.408
IL2RBinterleukin 2 receptor, beta0.395
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.388
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.380
FLNAfilamin A, alpha0.375
IRF4interferon regulatory factor 40.374
CCR1chemokine (C-C motif) receptor 10.371
BTN3A1butyrophilin, subfamily 3, member A10.359
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.359
IL10RAinterleukin 10 receptor, alpha0.345
CCL4chemokine (C-C motif) ligand 40.342
LST1leukocyte specific transcript 10.326
CTLA4cytotoxic T-lymphocyte-associated protein 40.320
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.314
NCF4neutrophil cytosolic factor 4, 40kDa0.286
CASP1caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)0.280
CFLARCASP8 and FADD-like apoptosis regulator0.279
HLA-DRB5major histocompatibility complex, class II, DR beta 50.279
BLNKB-cell linker0.270
CCL5chemokine (C-C motif) ligand 50.268
CD28CD28 molecule0.262
LTAlymphotoxin alpha (TNF superfamily, member 1)0.262
CLEC10AC-type lectin domain family 10, member A0.261
TIRAPtoll-interleukin 1 receptor (TIR) domain containing adaptor protein0.260
JAK1Janus kinase 10.256
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.254
MALT1mucosa associated lymphoid tissue lymphoma translocation gene 10.244
TAL1T-cell acute lymphocytic leukemia 10.243
SMAD7SMAD family member 70.237
FGF1fibroblast growth factor 1 (acidic)0.237
SIGLEC7sialic acid binding Ig-like lectin 70.228
IL4Rinterleukin 4 receptor0.227
CD2CD2 molecule0.223
PAX3paired box 30.208
MS4A6Amembrane-spanning 4-domains, subfamily A, member 6A0.203
AIF1allograft inflammatory factor 10.198
CCL22chemokine (C-C motif) ligand 220.198
NME1non-metastatic cells 1, protein (NM23A) expressed in0.197
LILRA6leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 60.194
HLA-DPB1major histocompatibility complex, class II, DP beta 10.188
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
mmp9matrix metalloproteinase 90.816
ptch2patched 20.531
tlr3toll-like receptor 30.463
shhasonic hedgehog a0.359
kitakit receptor a0.316
il6rinterleukin 6 receptor0.311
runx2arunt-related transcription factor 2a0.283
foxd3forkhead box D30.279
gmpsguanine monphosphate synthetase0.269
ahcyS-adenosylhomocysteine hydrolase0.263
myod1myogenic differentiation 10.257
fgf8afibroblast growth factor 8 a0.239
cdx4caudal type homeo box transcription factor 40.237
pnp4apurine nucleoside phosphorylase 4a0.230
igf2binsulin-like growth factor 2b0.208
erbb3bv-erb-b2 erythroblastic leukemia viral oncogene homolog 3b0.176
c1qccomplement component 1, q subcomponent, C chain0.172
wnt1wingless-type MMTV integration site family, member 10.172
cxcr4bchemokine (C-X-C motif), receptor 4b0.168
impdh1binosine 5'-phosphate dehydrogenase 1b0.152
ltkleukocyte tyrosine kinase0.149
lgals2alectin, galactoside-binding, soluble, 2a0.146
ptk6aPTK6 protein tyrosine kinase 6a0.133
syngr1asynaptogyrin 1a0.133
erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog0.129
gmfgglia maturation factor, gamma0.128
ivns1abpainfluenza virus NS1A binding protein a0.120
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.116
foxa2forkhead box A20.114
csf3rcolony stimulating factor 3 receptor (granulocyte)0.113
tlr2toll-like receptor 20.111
tfectranscription factor EC0.111
gpr182G protein-coupled receptor 1820.109
stc1lstanniocalcin 1, like0.108
pcdh8protocadherin 80.108
mmp15bmatrix metallopeptidase 15b0.104
atic5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase0.100
rag1recombination activating gene 10.099
LOC100003514protein kinase C alpha type-like0.099
tbpTATA box binding protein0.098
prps1aphosphoribosyl pyrophosphate synthetase 1A0.095
hsp90a.1heat shock protein 90-alpha 10.095
cdh1cadherin 1, epithelial0.091
sulf2lsulfatase 2, like0.089
mcm5MCM5 minichromosome maintenance deficient 5 (S. cerevisiae)0.088
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.088
rbp7bretinol binding protein 7b, cellular0.087
angptl2angiopoietin-like 20.087
aox3aldehyde oxidase 30.086
gpr143G protein-coupled receptor 1430.085
pdss1prenyl (decaprenyl) diphosphate synthase, subunit 10.085
ntn2netrin 20.084
s100a10bS100 calcium binding protein A10b0.084
ifng1-2interferon, gamma 1-20.083
cpoxcoproporphyrinogen oxidase0.082
taf3TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated facto0.082
med12mediator of RNA polymerase II transcription, subunit 12 homolog0.082
arpc1bactin related protein 2/3 complex, subunit 1B0.082
il22interleukin 220.082
agr2anterior gradient homolog 2 (Xenopus laevis)0.080
kcnh2potassium voltage-gated channel, subfamily H (eag-related), member 20.080
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.079
fgf3fibroblast growth factor 30.079
stac3SH3 and cysteine rich domain 30.078
angptl1angiopoietin-like 10.077
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.077
slc6a9solute carrier family 6 (neurotransmitter transporter, glycine), member 90.077
pdia4protein disulfide isomerase associated 40.076
lrrc33leucine rich repeat containing 330.076
btr16bloodthirsty-related gene family, member 160.076
emx2empty spiracles homeobox 20.076
bmi1bB lymphoma Mo-MLV insertion region 1b0.075
LOC100004946transient receptor potential cation channel subfamily M member 4-like0.075
vcanbversican b0.075
ugp2bUDP-glucose pyrophosphorylase 2b0.075
s100v2S100 calcium binding protein V20.074
ighmimmunoglobulin heavy constant mu and immunoglobulin heavy constant mu0.073
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.073
bmp6bone morphogenetic protein 60.073
disc1disrupted in schizophrenia 10.073
ocrloculocerebrorenal syndrome of Lowe0.073
tmem144btransmembrane protein 144b0.073
hspa9heat shock protein 90.072
caspacaspase a0.072
fcer1glFc receptor, IgE, high affinity I, gamma polypeptide like0.071
alkanaplastic lymphoma kinase (Ki-1)0.071
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Trp53transformation related protein 530.999
Ptenphosphatase and tensin homolog0.998
Ctnnb1catenin (cadherin associated protein), beta 10.996
Cd28CD28 antigen0.995
Bcl2l11BCL2-like 11 (apoptosis facilitator)0.993
Itgb1integrin beta 1 (fibronectin receptor beta)0.992
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.992
Nf1neurofibromatosis 10.988
LynYamaguchi sarcoma viral (v-yes-1) oncogene homolog0.988
Efnb2ephrin B20.986
Foxp3forkhead box P30.986
Icosinducible T-cell co-stimulator0.985
Tlr4toll-like receptor 40.983
Ighimmunoglobulin heavy chain complex0.980
Cd40CD40 antigen0.977
Tgfb1transforming growth factor, beta 10.975
Ptpn6protein tyrosine phosphatase, non-receptor type 60.973
Ikzf1IKAROS family zinc finger 10.967
Cd19CD19 antigen0.967
Ccr1chemokine (C-C motif) receptor 10.951
Socs1suppressor of cytokine signaling 10.948
Tnfaip3tumor necrosis factor, alpha-induced protein 30.946
Gli3GLI-Kruppel family member GLI30.943
Lyz2lysozyme 20.942
Zeb1zinc finger E-box binding homeobox 10.939
CblCasitas B-lineage lymphoma0.938
Dok1docking protein 10.931
Prf1perforin 1 (pore forming protein)0.929
Rnf2ring finger protein 20.921
Clec4nC-type lectin domain family 4, member n0.914
Cdkn1bcyclin-dependent kinase inhibitor 1B0.912
Ifnginterferon gamma0.903
Latlinker for activation of T cells0.902
Emx1empty spiracles homolog 1 (Drosophila)0.902
Sykbspleen tyrosine kinase0.897
Grb2growth factor receptor bound protein 20.891
Irf4interferon regulatory factor 40.878
Cd22CD22 antigen0.872
Itga3integrin alpha 30.870
Ltalymphotoxin A0.869
Tnftumor necrosis factor0.862
Jak2Janus kinase 20.855
Sfpi1SFFV proviral integration 10.849
Chrnb2cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)0.847
Vav1vav 1 oncogene0.843
Ikzf3IKAROS family zinc finger 30.837
Inpp5dinositol polyphosphate-5-phosphatase D0.830
FaslFas ligand (TNF superfamily, member 6)0.826
Casp8caspase 80.818
Cd96CD96 antigen0.815
Casp4caspase 4, apoptosis-related cysteine peptidase0.815
Birc3baculoviral IAP repeat-containing 30.814
Apcadenomatosis polyposis coli0.808
RybpRING1 and YY1 binding protein0.788
Cd72CD72 antigen0.787
Tnfrsf13ctumor necrosis factor receptor superfamily, member 13c0.777
Cd4CD4 antigen0.777
Trp63transformation related protein 630.770
Ccr7chemokine (C-C motif) receptor 70.766
Ccr9chemokine (C-C motif) receptor 90.765
Cdk4cyclin-dependent kinase 40.763
Ccnd1cyclin D10.752
Casp1caspase 10.744
C3ar1complement component 3a receptor 10.744
Pax5paired box gene 50.744
Dok2docking protein 20.743
Lef1lymphoid enhancer binding factor 10.740
Pcsk5proprotein convertase subtilisin/kexin type 50.735
Pdcd1programmed cell death 10.733
Irf8interferon regulatory factor 80.729
Kitkit oncogene0.723
Mmp9matrix metallopeptidase 90.718
Tnfrsf4tumor necrosis factor receptor superfamily, member 40.715
Irf5interferon regulatory factor 50.710
Fgfr2fibroblast growth factor receptor 20.706
Bcl2B-cell leukemia/lymphoma 20.703
Trp73transformation related protein 730.701
Il1binterleukin 1 beta0.693
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.691
Cyldcylindromatosis (turban tumor syndrome)0.687
Tnfrsf13btumor necrosis factor receptor superfamily, member 13b0.685
Ltblymphotoxin B0.682
Il27rainterleukin 27 receptor, alpha0.682
Kitlkit ligand0.680
Stat3signal transducer and activator of transcription 30.672
Card11caspase recruitment domain family, member 110.671
Rb1retinoblastoma 10.671
Ptpn11protein tyrosine phosphatase, non-receptor type 110.666
Ccl5chemokine (C-C motif) ligand 50.659
Il4interleukin 40.655
Smad4MAD homolog 4 (Drosophila)0.650
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.648
Myd88myeloid differentiation primary response gene 880.646
Foxc1forkhead box C10.644
Ikbkginhibitor of kappaB kinase gamma0.641
Cd5CD5 antigen0.639
Slc6a3solute carrier family 6 (neurotransmitter transporter, dopamine), member 30.638
Msr1macrophage scavenger receptor 10.632
Gli2GLI-Kruppel family member GLI20.630
Ifnar1interferon (alpha and beta) receptor 10.629
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
RT1-DaRT1 class II, locus Da0.650
Cd37CD37 molecule0.386
RT1-BaRT1 class II, locus Ba0.358
RT1-Db1RT1 class II, locus Db10.136
Casp1caspase 10.120
Il2rbinterleukin 2 receptor, beta0.119
Cd247Cd247 molecule0.118
Ptprcprotein tyrosine phosphatase, receptor type, C0.107
Psmb9proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)0.104
Ciitaclass II, major histocompatibility complex, transactivator0.101
Cd2Cd2 molecule0.096
Anxa2annexin A20.094
RT1-DMbRT1 class II, locus DMb0.092
Fcgr2aFc fragment of IgG, low affinity IIa, receptor (CD32)0.085
Hckhemopoietic cell kinase0.077
Cd5Cd5 molecule0.076
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.065
Nkg7natural killer cell group 7 sequence0.065
Il1binterleukin 1 beta0.065
Grin2aglutamate receptor, ionotropic, N-methyl D-aspartate 2A0.063
Reg3bregenerating islet-derived 3 beta0.058
Cd44Cd44 molecule0.053
RT1-DMaRT1 class II, locus DMa0.052
Ptafrplatelet-activating factor receptor0.051
Cd38CD38 molecule0.046
Inpp5dinositol polyphosphate-5-phosphatase D0.046
Il10interleukin 100.046
Fgfr2fibroblast growth factor receptor 20.040
FgrGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.040
Il1r1interleukin 1 receptor, type I0.038
Ctsbcathepsin B0.037
Laptm5lysosomal protein transmembrane 50.037
Gzmkgranzyme K0.037
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.036
Cfpcomplement factor properdin0.036
Hsd3b1hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 10.035
Cd53Cd53 molecule0.034
Col10a1collagen, type X, alpha 10.033
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.032
Ccr5chemokine (C-C motif) receptor 50.032
Bin2bridging integrator 20.032
Ly86lymphocyte antigen 860.031
Zbp1Z-DNA binding protein 10.030
Mvpmajor vault protein0.030
Prr13proline rich 130.029
Icosinducible T-cell co-stimulator0.029
Cd4Cd4 molecule0.029
Ets1v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)0.027
P2ry6pyrimidinergic receptor P2Y, G-protein coupled, 60.027
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.027
Elf1E74-like factor 10.027
Lcp2lymphocyte cytosolic protein 20.026
Dock8dedicator of cytokinesis 80.026
Pthparathyroid hormone0.026
Hspa8heat shock protein 80.025
Tas2r123taste receptor, type 2, member 1230.025
F2rl2coagulation factor II (thrombin) receptor-like 20.025
Napsanapsin A aspartic peptidase0.025
Rassf5Ras association (RalGDS/AF-6) domain family member 50.025
Fgbfibrinogen beta chain0.024
Nr5a2nuclear receptor subfamily 5, group A, member 20.024
Pfn1profilin 10.023
Aldh6a1aldehyde dehydrogenase 6 family, member A10.023
Nos3nitric oxide synthase 3, endothelial cell0.023
Il2rginterleukin 2 receptor, gamma0.023
Gpr20G protein-coupled receptor 200.023
Zg16zymogen granule protein 160.022
Ripk1receptor (TNFRSF)-interacting serine-threonine kinase 10.022
Ptger4prostaglandin E receptor 4 (subtype EP4)0.022
Il6interleukin 60.022
Arpc1bactin related protein 2/3 complex, subunit 1B0.022
RT1-BbRT1 class II, locus Bb0.021
Akr1b8aldo-keto reductase family 1, member B80.021
Gmfgglia maturation factor, gamma0.021
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.020
Mcpt2mast cell protease 20.020
Lyz2lysozyme 20.020
Glp2rglucagon-like peptide 2 receptor0.020
Prl8a9prolactin family 8, subfamily a, member 90.020
Arhgap4Rho GTPase activating protein 40.020
Apbb1ipamyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein0.020
Itgb7integrin, beta 70.020
Vom2r27vomeronasal 2 receptor, 270.019
Aif1allograft inflammatory factor 10.019
Slfn2schlafen 20.019
Plcg2phospholipase C, gamma 20.019
Slc18a2solute carrier family 18 (vesicular monoamine), member 20.019
LOC100361706lambda-chain C1-region-like0.019
Il4interleukin 40.019
Lcp1lymphocyte cytosolic protein 10.019
Ptpn6protein tyrosine phosphatase, non-receptor type 60.019
MosMoloney sarcoma oncogene0.018
Kcnh7potassium voltage-gated channel, subfamily H (eag-related), member 70.018
Trhr2thyrotropin releasing hormone receptor 20.018
Serpinb1aserine (or cysteine) proteinase inhibitor, clade B, member 1a0.018
Il2rainterleukin 2 receptor, alpha0.018
Il17rainterleukin 17 receptor A0.018
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism