The network for 'positive regulation of interleukin 5 production' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of interleukin 5 production

Any process that activates or increases the frequency, rate, or extent of interleukin-5 production.

NameDescriptionProbabilityFunc Analog Organism
RXRAretinoid X receptor, alpha1.000
MED25mediator complex subunit 251.000
TAL1T-cell acute lymphocytic leukemia 11.000
NCOA1nuclear receptor coactivator 11.000
PARD6Apar-6 partitioning defective 6 homolog alpha (C. elegans)0.999
RARAretinoic acid receptor, alpha0.991
PHYHIPLphytanoyl-CoA 2-hydroxylase interacting protein-like0.985
NCOR2nuclear receptor corepressor 20.979
ZNF71zinc finger protein 710.925
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.923
PARD6Bpar-6 partitioning defective 6 homolog beta (C. elegans)0.880
RXRBretinoid X receptor, beta0.877
CCDC115coiled-coil domain containing 1150.870
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.843
NUMBnumb homolog (Drosophila)0.803
PPARAperoxisome proliferator-activated receptor alpha0.801
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.773
ITGB1BP2integrin beta 1 binding protein (melusin) 20.718
NMT2N-myristoyltransferase 20.681
NR4A3nuclear receptor subfamily 4, group A, member 30.572
MED1mediator complex subunit 10.539
TBX5T-box 50.462
RXRGretinoid X receptor, gamma0.454
KANK2KN motif and ankyrin repeat domains 20.413
AP2A1adaptor-related protein complex 2, alpha 1 subunit0.350
F11RF11 receptor0.249
KLF13Kruppel-like factor 130.243
PRKD2protein kinase D20.224
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.218
AKT1v-akt murine thymoma viral oncogene homolog 10.211
LLGL1lethal giant larvae homolog 1 (Drosophila)0.201
TRIM32tripartite motif containing 320.201
MTORmechanistic target of rapamycin (serine/threonine kinase)0.198
RUNX1runt-related transcription factor 10.197
PDPK13-phosphoinositide dependent protein kinase-10.193
SORBS3sorbin and SH3 domain containing 30.178
GATA1GATA binding protein 1 (globin transcription factor 1)0.163
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.155
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.131
BCL3B-cell CLL/lymphoma 30.115
CREBBPCREB binding protein0.111
NR4A2nuclear receptor subfamily 4, group A, member 20.109
PPP2R4protein phosphatase 2A activator, regulatory subunit 40.102
ZFPM1zinc finger protein, multitype 10.101
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.097
AKT3v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)0.096
ESR1estrogen receptor 10.094
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.087
LMO2LIM domain only 2 (rhombotin-like 1)0.086
GATA2GATA binding protein 20.085
NCOA6nuclear receptor coactivator 60.078
SKIv-ski sarcoma viral oncogene homolog (avian)0.078
PGRprogesterone receptor0.076
NR2F6nuclear receptor subfamily 2, group F, member 60.074
NCOA3nuclear receptor coactivator 30.066
FOXJ1forkhead box J10.064
ITGA2Bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)0.064
PRKCIprotein kinase C, iota0.063
LRRK2leucine-rich repeat kinase 20.057
DENND5ADENN/MADD domain containing 5A0.056
NCOR1nuclear receptor corepressor 10.054
CREMcAMP responsive element modulator0.054
STK4serine/threonine kinase 40.050
CASKcalcium/calmodulin-dependent serine protein kinase (MAGUK family)0.048
NR5A1nuclear receptor subfamily 5, group A, member 10.047
ADAP1ArfGAP with dual PH domains 10.044
LLGL2lethal giant larvae homolog 2 (Drosophila)0.043
AMHR2anti-Mullerian hormone receptor, type II0.042
TADA3transcriptional adaptor 30.042
NR1H3nuclear receptor subfamily 1, group H, member 30.041
ASXL1additional sex combs like 1 (Drosophila)0.041
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.041
PDE4Dphosphodiesterase 4D, cAMP-specific0.041
WWC1WW and C2 domain containing 10.040
THRAthyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian)0.037
SPOPspeckle-type POZ protein0.037
PDE4Bphosphodiesterase 4B, cAMP-specific0.037
SPI1spleen focus forming virus (SFFV) proviral integration oncogene spi10.037
SRFserum response factor (c-fos serum response element-binding transcription factor)0.037
CEBPACCAAT/enhancer binding protein (C/EBP), alpha0.036
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.035
KLF1Kruppel-like factor 1 (erythroid)0.035
ACVR1Bactivin A receptor, type IB0.034
PPARGperoxisome proliferator-activated receptor gamma0.034
THEM4thioesterase superfamily member 40.033
NR1D1nuclear receptor subfamily 1, group D, member 10.033
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.033
ZBTB16zinc finger and BTB domain containing 160.033
HRhairless homolog (mouse)0.033
PDE7Bphosphodiesterase 7B0.031
ZNF576zinc finger protein 5760.030
NPAS2neuronal PAS domain protein 20.030
PPARGC1Aperoxisome proliferator-activated receptor gamma, coactivator 1 alpha0.029
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.028
MAPK7mitogen-activated protein kinase 70.028
MYL4myosin, light chain 4, alkali; atrial, embryonic0.027
SPIN1spindlin 10.027
SPHK1sphingosine kinase 10.026
GATA4GATA binding protein 40.026
DHHdesert hedgehog0.025
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Gata4GATA binding protein 40.690
Rxraretinoid X receptor alpha0.470
Gata6GATA binding protein 60.401
Il1rl1interleukin 1 receptor-like 10.145
Rargretinoic acid receptor, gamma0.123
Ilkintegrin linked kinase0.117
Mmp8matrix metallopeptidase 80.082
Akt1thymoma viral proto-oncogene 10.074
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.063
Ptpn22protein tyrosine phosphatase, non-receptor type 22 (lymphoid)0.062
Vegfavascular endothelial growth factor A0.054
Tlr4toll-like receptor 40.040
Gata5GATA binding protein 50.040
Ppargperoxisome proliferator activated receptor gamma0.026
Gfi1bgrowth factor independent 1B0.026
Mesp1mesoderm posterior 10.025
Zfpm2zinc finger protein, multitype 20.025
Bcl2B-cell leukemia/lymphoma 20.023
Cd44CD44 antigen0.022
Tal1T-cell acute lymphocytic leukemia 10.022
Ptpn11protein tyrosine phosphatase, non-receptor type 110.020
Il33interleukin 330.019
Pparaperoxisome proliferator activated receptor alpha0.018
Vhlvon Hippel-Lindau tumor suppressor0.018
Il6interleukin 60.017
Ldb3LIM domain binding 30.015
Runx1runt related transcription factor 10.015
Soat2sterol O-acyltransferase 20.015
Foxc2forkhead box C20.015
Icosinducible T-cell co-stimulator0.014
Zfpm1zinc finger protein, multitype 10.014
Sox4SRY-box containing gene 40.013
Cd40CD40 antigen0.013
Klf3Kruppel-like factor 3 (basic)0.012
Hoxa1homeobox A10.012
Akt2thymoma viral proto-oncogene 20.011
Il18rapinterleukin 18 receptor accessory protein0.011
Pard3par-3 (partitioning defective 3) homolog (C. elegans)0.010
Pax2paired box gene 20.010
Stat6signal transducer and activator of transcription 60.010
Gpr97G protein-coupled receptor 970.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism