The network for 'muscle cell cellular homeostasis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

muscle cell cellular homeostasis

The cellular homeostatic process that preserves a muscle cell in a stable functional or structural state.

NameDescriptionProbabilityFunc Analog Organism
TPI1triosephosphate isomerase 10.935
GAPDHglyceraldehyde-3-phosphate dehydrogenase0.774
ENO1enolase 1, (alpha)0.761
PGK1phosphoglycerate kinase 10.720
ABCA1ATP-binding cassette, sub-family A (ABC1), member 10.462
SPTA1spectrin, alpha, erythrocytic 1 (elliptocytosis 2)0.357
MTMR12myotubularin related protein 120.315
SPTAN1spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)0.314
ACTG1actin, gamma 10.290
MKL1megakaryoblastic leukemia (translocation) 10.266
LDHAlactate dehydrogenase A0.256
ANK1ankyrin 1, erythrocytic0.164
DTNAdystrobrevin, alpha0.160
PGAM1phosphoglycerate mutase 1 (brain)0.160
GPIglucose-6-phosphate isomerase0.132
VHLvon Hippel-Lindau tumor suppressor0.107
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.106
PFKLphosphofructokinase, liver0.102
EGLN3egl nine homolog 3 (C. elegans)0.101
HSP90AB1heat shock protein 90kDa alpha (cytosolic), class B member 10.083
DTNBdystrobrevin, beta0.083
KAT2BK(lysine) acetyltransferase 2B0.078
NDEL1nudE nuclear distribution gene E homolog (A. nidulans)-like 10.078
ACTBactin, beta0.074
PKM2pyruvate kinase, muscle0.074
DMDdystrophin0.070
IL6Rinterleukin 6 receptor0.069
CXCL2chemokine (C-X-C motif) ligand 20.069
EIF4A1eukaryotic translation initiation factor 4A10.069
DAG1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.063
EGLN1egl nine homolog 1 (C. elegans)0.061
SNTB1syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)0.058
MKL2MKL/myocardin-like 20.058
BCAT2branched chain amino-acid transaminase 2, mitochondrial0.057
SSX4synovial sarcoma, X breakpoint 40.057
SYNMsynemin, intermediate filament protein0.057
APOHapolipoprotein H (beta-2-glycoprotein I)0.055
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.053
IRF2interferon regulatory factor 20.051
SLC25A6solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 60.050
MYOCDmyocardin0.050
CLIP1CAP-GLY domain containing linker protein 10.049
CHRNA1cholinergic receptor, nicotinic, alpha 1 (muscle)0.047
DSTdystonin0.045
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.043
OS9osteosarcoma amplified 9, endoplasmic reticulum lectin0.042
PLD3phospholipase D family, member 30.040
RPL8ribosomal protein L80.040
UTRNutrophin0.039
VDAC1voltage-dependent anion channel 10.039
OBSCNobscurin, cytoskeletal calmodulin and titin-interacting RhoGEF0.039
IFNAR2interferon (alpha, beta and omega) receptor 20.038
NCOA6nuclear receptor coactivator 60.037
EEF2eukaryotic translation elongation factor 20.036
PSAPprosaposin0.036
SREBF2sterol regulatory element binding transcription factor 20.035
PQBP1polyglutamine binding protein 10.035
MYL4myosin, light chain 4, alkali; atrial, embryonic0.035
CTSDcathepsin D0.034
TKTtransketolase0.033
RDH11retinol dehydrogenase 11 (all-trans/9-cis/11-cis)0.032
EPAS1endothelial PAS domain protein 10.032
PPIApeptidylprolyl isomerase A (cyclophilin A)0.030
NCOA1nuclear receptor coactivator 10.029
FBXO30F-box protein 300.028
FBLfibrillarin0.028
NUDT3nudix (nucleoside diphosphate linked moiety X)-type motif 30.028
HLA-DPB1major histocompatibility complex, class II, DP beta 10.028
CHRNDcholinergic receptor, nicotinic, delta0.027
MYOD1myogenic differentiation 10.027
BNIP3BCL2/adenovirus E1B 19kDa interacting protein 30.027
KCNJ5potassium inwardly-rectifying channel, subfamily J, member 50.027
NUCB1nucleobindin 10.027
EIF3Deukaryotic translation initiation factor 3, subunit D0.026
MIFmacrophage migration inhibitory factor (glycosylation-inhibiting factor)0.026
SMAD9SMAD family member 90.026
GOLM1golgi membrane protein 10.025
APCadenomatous polyposis coli0.025
ERBB2IPerbb2 interacting protein0.025
ATP5A1ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle0.024
SHOC2soc-2 suppressor of clear homolog (C. elegans)0.024
HNRNPH2heterogeneous nuclear ribonucleoprotein H2 (H')0.024
WDR83WD repeat domain 830.024
NOB1NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)0.023
ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 10.023
IL8interleukin 80.023
HIF1ANhypoxia inducible factor 1, alpha subunit inhibitor0.022
NCOA2nuclear receptor coactivator 20.022
ZFP106zinc finger protein 106 homolog (mouse)0.022
UBR3ubiquitin protein ligase E3 component n-recognin 3 (putative)0.022
MAN2B1mannosidase, alpha, class 2B, member 10.022
KCNRGpotassium channel regulator0.022
C12orf10chromosome 12 open reading frame 100.022
FKBP4FK506 binding protein 4, 59kDa0.021
CEBPBCCAAT/enhancer binding protein (C/EBP), beta0.021
GRNgranulin0.021
GIGYF2GRB10 interacting GYF protein 20.021
WBSCR22Williams Beuren syndrome chromosome region 220.021
TNIKTRAF2 and NCK interacting kinase0.020
MACF1microtubule-actin crosslinking factor 10.020
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
slo-1Protein SLO-10.936
dyb-1Protein DYB-10.185
spc-1Protein SPC-10.179
T21B6.3Protein T21B6.30.142
stn-1Protein STN-10.098
emb-9Protein EMB-90.077
pat-12Protein PAT-120.056
zyx-1Protein ZYX-10.048
hsp-12.2Protein HSP-12.20.047
F01G4.6Protein F01G4.60.046
myo-3Protein MYO-30.035
C10E2.6Protein C10E2.60.029
dys-1Protein DYS-10.026
alh-8Protein ALH-80.026
pcca-1Protein PCCA-10.025
dyc-1Protein DYC-10.024
goa-1Protein GOA-10.022
ant-1.3Protein ANT-1.30.020
inx-2Protein INX-20.020
pkg-1Protein PKG-10.019
sorb-1Protein SORB-10.017
lgc-34Protein LGC-340.017
C06G3.6Protein C06G3.60.017
ajm-1Protein AJM-10.015
gpb-1Protein GPB-10.015
act-3Protein ACT-30.015
unc-1Protein UNC-10.014
let-2Protein LET-20.013
ifa-1Protein IFA-10.013
CELE_C08H9.2Protein C08H9.20.012
tbc-9Protein TBC-90.012
unc-87Protein UNC-870.011
ant-1.4Protein ANT-1.40.011
mig-6Protein MIG-60.011
C53C9.2Protein C53C9.20.010
col-43Protein COL-430.010
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
smyd1bSET and MYND domain containing 1b0.547
myhz1.1myosin, heavy polypeptide 1.1, skeletal muscle0.180
lama2laminin, alpha 20.159
actn2actinin, alpha 20.158
actn3aactinin alpha 3a0.108
ttnatitin a0.093
tnnc1btroponin C type 1b (slow)0.075
lamb2laminin, beta 2 (laminin S)0.050
LOC100149148novel protein similar to myosin heavy chain 4 (myhc4)0.044
smyhc1slow myosin heavy chain 10.041
acta1aactin, alpha 1a, skeletal muscle0.040
pafah1b1aplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit a0.039
dag1dystroglycan 10.038
pgam2phosphoglycerate mutase 2 (muscle)0.037
cdkn1ccyclin-dependent kinase inhibitor 1C (p57, Kip2)0.036
tnni2a.4troponin I, skeletal, fast 2a.40.034
smyhc1lslow myosin heavy chain 1, like0.034
pafah1b1bplatelet-activating factor acetylhydrolase, isoform Ib, alpha subunit b0.034
smyhc2slow myosin heavy chain 20.033
tnnt1troponin T1, skeletal, slow0.032
xirp1xin actin-binding repeat containing 10.032
ldb3aLIM-domain binding factor 3a0.031
st8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.029
tnnt3atroponin T3a, skeletal, fast0.026
mef2dmyocyte enhancer factor 2d0.025
actn3bactinin alpha 3b0.023
tmem38atransmembrane protein 38A0.022
ppargc1alperoxisome proliferator-activated receptor gamma, coactivator 1 alpha like0.022
lamc1laminin, gamma 10.022
tnni1altroponin I, skeletal, slow like0.021
myf6myogenic factor 60.018
dmddystrophin0.017
myhz1.2myosin, heavy polypeptide 1.2, skeletal muscle0.017
zplxdc2plexin domain containing 20.015
tpm2tropomyosin 2 (beta)0.014
dhfrdihydrofolate reductase0.014
zgc:66097zgc:660970.012
muskmuscle, skeletal, receptor tyrosine kinase0.012
LOC569128hypothetical protein LOC5691280.012
myhz2myosin, heavy polypeptide 2, fast muscle specific0.012
klfdKruppel-like factor d0.011
card9caspase recruitment domain family, member 90.011
eng1aengrailed 1a0.010
sarsseryl-tRNA synthetase0.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Dmddystrophin, muscular dystrophy0.989
Ptgs2prostaglandin-endoperoxide synthase 20.760
Nos1nitric oxide synthase 1, neuronal0.736
Dag1dystroglycan 10.480
Cav1caveolin 1, caveolae protein0.405
Robo1roundabout homolog 1 (Drosophila)0.303
Nr3c1nuclear receptor subfamily 3, group C, member 10.229
Leprleptin receptor0.178
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.137
Plauplasminogen activator, urokinase0.137
Slit3slit homolog 3 (Drosophila)0.133
Sgcgsarcoglycan, gamma (dystrophin-associated glycoprotein)0.104
Snta1syntrophin, acidic 10.094
Ptrfpolymerase I and transcript release factor0.090
Insrinsulin receptor0.089
Mmp9matrix metallopeptidase 90.086
Dtnadystrobrevin alpha0.085
Sgcasarcoglycan, alpha (dystrophin-associated glycoprotein)0.079
Ndel1nuclear distribution gene E-like homolog 1 (A. nidulans)0.069
Slit2slit homolog 2 (Drosophila)0.066
Egln1EGL nine homolog 1 (C. elegans)0.065
Actn3actinin alpha 30.064
Lama2laminin, alpha 20.064
Sgcbsarcoglycan, beta (dystrophin-associated glycoprotein)0.056
Cav3caveolin 30.052
Nos3nitric oxide synthase 3, endothelial cell0.047
Il6stinterleukin 6 signal transducer0.045
Ptpn11protein tyrosine phosphatase, non-receptor type 110.045
Tlr4toll-like receptor 40.043
Rpgrip1lRpgrip1-like0.042
Tnni1troponin I, skeletal, slow 10.037
Csrp3cysteine and glycine-rich protein 30.034
Robo2roundabout homolog 2 (Drosophila)0.033
Desdesmin0.033
Fkrpfukutin related protein0.032
Rps2ribosomal protein S20.032
Vhlvon Hippel-Lindau tumor suppressor0.032
Eef1a1eukaryotic translation elongation factor 1 alpha 10.032
Dysfdysferlin0.031
Kif5akinesin family member 5A0.030
Egfrepidermal growth factor receptor0.030
Rpl28ribosomal protein L280.029
Dtnbp1dystrobrevin binding protein 10.029
Tnnt2troponin T2, cardiac0.028
Sntb1syntrophin, basic 10.028
Plgplasminogen0.026
Esr2estrogen receptor 2 (beta)0.025
Rps3ribosomal protein S30.025
Bmpr2bone morphogenic protein receptor, type II (serine/threonine kinase)0.024
Ghrgrowth hormone receptor0.024
Pfklphosphofructokinase, liver, B-type0.024
Ldhalactate dehydrogenase A0.023
Hspb7heat shock protein family, member 7 (cardiovascular)0.023
Gckglucokinase0.023
Stat3signal transducer and activator of transcription 30.023
Myom1myomesin 10.022
Gapdhglyceraldehyde-3-phosphate dehydrogenase0.022
Fktnfukutin0.022
Nrapnebulin-related anchoring protein0.022
Apoa1apolipoprotein A-I0.022
Ywhaztyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide0.021
Ahraryl-hydrocarbon receptor0.021
Trim54tripartite motif-containing 540.021
F2coagulation factor II0.021
Sult5a1sulfotransferase family 5A, member 10.020
Agtr2angiotensin II receptor, type 20.020
Spna2spectrin alpha 20.020
Smad3MAD homolog 3 (Drosophila)0.019
Gja1gap junction protein, alpha 10.019
Clip1CAP-GLY domain containing linker protein 10.019
Hnf4ahepatic nuclear factor 4, alpha0.019
Platplasminogen activator, tissue0.018
Vegfavascular endothelial growth factor A0.018
Arntaryl hydrocarbon receptor nuclear translocator0.018
Arandrogen receptor0.018
Srpk3serine/arginine-rich protein specific kinase 30.018
Ppargperoxisome proliferator activated receptor gamma0.018
Cacng1calcium channel, voltage-dependent, gamma subunit 10.017
Rplp0ribosomal protein, large, P00.016
Ctnnb1catenin (cadherin associated protein), beta 10.016
Apoeapolipoprotein E0.016
Chrngcholinergic receptor, nicotinic, gamma polypeptide0.016
Add2adducin 2 (beta)0.016
Wnt11wingless-related MMTV integration site 110.016
Ldb3LIM domain binding 30.015
Mpdzmultiple PDZ domain protein0.015
Itga7integrin alpha 70.015
Actc1actin, alpha, cardiac muscle 10.014
Nde1nuclear distribution gene E homolog 1 (A nidulans)0.014
Rock2Rho-associated coiled-coil containing protein kinase 20.014
Kif1bkinesin family member 1B0.013
Phka1phosphorylase kinase alpha 10.013
P4htmprolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)0.013
Asgr2asialoglycoprotein receptor 20.012
Bmpr1abone morphogenetic protein receptor, type 1A0.012
Cyp2d10cytochrome P450, family 2, subfamily d, polypeptide 100.012
Pgam2phosphoglycerate mutase 20.012
Largelike-glycosyltransferase0.012
Mid2midline 20.012
Myh6myosin, heavy polypeptide 6, cardiac muscle, alpha0.012
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Mdh1malate dehydrogenase 1, NAD (soluble)0.021
Slc25a3solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 30.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism