The network for 'nephric duct development' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

nephric duct development

The process whose specific outcome is the progression of a nephric duct over time, from its initial formation to a mature structure. A nephric duct is a tube that drains a primitive kidney.

NameDescriptionProbabilityFunc Analog Organism
BMPR1Abone morphogenetic protein receptor, type IA0.999
NOTCH1notch 10.990
SPENspen homolog, transcriptional regulator (Drosophila)0.929
NCOR2nuclear receptor corepressor 20.903
ATXN1Lataxin 1-like0.900
TRPC1transient receptor potential cation channel, subfamily C, member 10.692
MAML1mastermind-like 1 (Drosophila)0.620
DVL3dishevelled, dsh homolog 3 (Drosophila)0.315
FGF18fibroblast growth factor 180.294
ATP6V0CATPase, H+ transporting, lysosomal 16kDa, V0 subunit c0.283
ARPC4actin related protein 2/3 complex, subunit 4, 20kDa0.191
PAX8paired box 80.155
JAG1jagged 10.131
BBS1Bardet-Biedl syndrome 10.102
SNW1SNW domain containing 10.098
CACNA1Gcalcium channel, voltage-dependent, T type, alpha 1G subunit0.090
ATP6V0BATPase, H+ transporting, lysosomal 21kDa, V0 subunit b0.087
WIF1WNT inhibitory factor 10.087
COL2A1collagen, type II, alpha 10.086
FOXC2forkhead box C2 (MFH-1, mesenchyme forkhead 1)0.085
TAOK1TAO kinase 10.085
CIR1corepressor interacting with RBPJ, 10.084
NOTCH3notch 30.080
FGF4fibroblast growth factor 40.075
NOGnoggin0.073
WNT4wingless-type MMTV integration site family, member 40.072
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 20.069
NPHP1nephronophthisis 1 (juvenile)0.067
SFRP1secreted frizzled-related protein 10.063
PAMpeptidylglycine alpha-amidating monooxygenase0.060
HES2hairy and enhancer of split 2 (Drosophila)0.057
FGF8fibroblast growth factor 8 (androgen-induced)0.056
PGRprogesterone receptor0.055
HOXA11homeobox A110.055
FGF3fibroblast growth factor 30.051
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)0.051
ATXN1ataxin 10.049
HNF1AHNF1 homeobox A0.049
LBX1ladybird homeobox 10.049
CSF2colony stimulating factor 2 (granulocyte-macrophage)0.047
FOXL1forkhead box L10.046
NAPAN-ethylmaleimide-sensitive factor attachment protein, alpha0.045
WNT7Awingless-type MMTV integration site family, member 7A0.044
NEU1sialidase 1 (lysosomal sialidase)0.042
IHHIndian hedgehog0.041
PPARAperoxisome proliferator-activated receptor alpha0.040
MMP11matrix metallopeptidase 11 (stromelysin 3)0.040
PAX2paired box 20.039
NOTCH2notch 20.037
ST8SIA2ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 20.037
ZFYVE9zinc finger, FYVE domain containing 90.037
HOXC8homeobox C80.037
ENTPD2ectonucleoside triphosphate diphosphohydrolase 20.036
RAXretina and anterior neural fold homeobox0.036
RHBGRh family, B glycoprotein (gene/pseudogene)0.036
BMP4bone morphogenetic protein 40.035
HNF4Ahepatocyte nuclear factor 4, alpha0.033
CRLF1cytokine receptor-like factor 10.033
GPR161G protein-coupled receptor 1610.032
FSTL1follistatin-like 10.032
DVL1dishevelled, dsh homolog 1 (Drosophila)0.032
DLX4distal-less homeobox 40.032
SLC6A2solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 20.031
SLC18A3solute carrier family 18 (vesicular acetylcholine), member 30.031
BMPR1Bbone morphogenetic protein receptor, type IB0.031
SIM2single-minded homolog 2 (Drosophila)0.031
DIAPH1diaphanous homolog 1 (Drosophila)0.031
PDX1pancreatic and duodenal homeobox 10.031
OTX2orthodenticle homeobox 20.031
GRIN2Dglutamate receptor, ionotropic, N-methyl D-aspartate 2D0.030
FOXE1forkhead box E1 (thyroid transcription factor 2)0.030
WNT11wingless-type MMTV integration site family, member 110.029
OTPorthopedia homeobox0.029
TLX3T-cell leukemia homeobox 30.029
GDNFglial cell derived neurotrophic factor0.029
ATP6AP1ATPase, H+ transporting, lysosomal accessory protein 10.029
AQP5aquaporin 50.028
SHHsonic hedgehog0.028
NPAS1neuronal PAS domain protein 10.028
FZD8frizzled homolog 8 (Drosophila)0.028
HS3ST6heparan sulfate (glucosamine) 3-O-sulfotransferase 60.027
HMX1H6 family homeobox 10.027
CYP26A1cytochrome P450, family 26, subfamily A, polypeptide 10.027
PALMparalemmin0.027
TAL1T-cell acute lymphocytic leukemia 10.026
POU3F1POU class 3 homeobox 10.026
P2RX2purinergic receptor P2X, ligand-gated ion channel, 20.025
NKX2-1NK2 homeobox 10.025
SYDE1synapse defective 1, Rho GTPase, homolog 1 (C. elegans)0.025
RPS6KA6ribosomal protein S6 kinase, 90kDa, polypeptide 60.025
FOXF2forkhead box F20.025
COL13A1collagen, type XIII, alpha 10.024
HOXD10homeobox D100.024
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.024
JAG2jagged 20.024
SIX5SIX homeobox 50.024
PYYpeptide YY0.024
HOXD3homeobox D30.023
RBPMSRNA binding protein with multiple splicing0.023
SFRP5secreted frizzled-related protein 50.023
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
bmp4bone morphogenetic protein 40.817
hnf1baHNF1 homeobox Ba0.710
wt1bwilms tumor 1b0.632
osr2odd-skipped related 2 (Drosophila)0.514
pax2apaired box gene 2a0.302
bmp2bbone morphogenetic protein 2b0.208
nphs2nephrosis 2, idiopathic, steroid-resistant (podocin)0.207
epha4aeph receptor A4a0.205
myod1myogenic differentiation 10.184
tbx20T-box 200.144
wnt9awingless-type MMTV integration site family, member 9A0.144
chrna4cholinergic receptor, nicotinic, alpha 40.144
dccdeleted in colorectal carcinoma0.141
flhfloating head0.131
fgf8afibroblast growth factor 8 a0.128
myf5myogenic factor 50.125
tal1T-cell acute lymphocytic leukemia 10.121
osr1odd-skipped related 1 (Drosophila)0.115
lhx1aLIM homeobox 1a0.110
wtipWilms tumor 1 interacting protein0.097
ntlano tail a0.088
plce1phospholipase C, epsilon 10.088
chdchordin0.081
shhasonic hedgehog a0.077
wnt1wingless-type MMTV integration site family, member 10.076
gscgoosecoid0.075
tcf21transcription factor 210.075
hnf1bbHNF1 homeobox Bb0.074
vegfaavascular endothelial growth factor Aa0.074
prdm1aPR domain containing 1a, with ZNF domain0.072
hapln1ahyaluronan and proteoglycan link protein 1a0.070
mecomMDS1 and EVI1 complex locus0.069
aldh1a2aldehyde dehydrogenase 1 family, member A20.063
lmx1b.1LIM homeobox transcription factor 1, beta 10.062
jag2jagged 20.061
irx4biroquois homeobox protein 4b0.057
slc12a3solute carrier family 12 (sodium/chloride transporters), member 30.054
hand2heart and neural crest derivatives expressed transcript 20.054
sema3dsemaphorin 3d0.054
hoxb2ahomeo box B2a0.053
nppanatriuretic peptide precursor A0.052
wu:fv91b12wu:fv91b120.050
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.050
tbx16T-box gene 160.048
coblcordon-bleu homolog (mouse)0.047
mafbav-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)0.046
foxj1bforkhead box J1b0.044
myl7myosin, light polypeptide 7, regulatory0.039
tbx1T-box 10.039
pea3ETS-domain transcription factor pea30.039
cyp26c1cytochrome P450, family 26, subfamily C, polypeptide 10.037
fzd5frizzled homolog 50.037
nfatc1nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 10.037
nkx2.2aNK2 transcription factor related 2a0.037
eomesaeomesodermin homolog a0.037
hoxc6ahomeo box C6a0.036
chrna2acholinergic receptor, nicotinic, alpha polypeptide 2a (neuronal)0.033
wt1awilms tumor 1a0.033
gbx2gastrulation brain homeo box 20.032
prox2prospero homeobox 20.031
eng2aengrailed 2a0.031
slc4a4asolute carrier family 4, member 4a0.030
hoxa13ahomeo box A13a0.029
fli1afriend leukemia integration 1a0.029
grem2gremlin 2, cysteine knot superfamily0.028
foxd3forkhead box D30.028
robo2roundabout homolog 20.028
hgfahepatocyte growth factor a0.028
trim3atripartite motif-containing 3a0.027
foxa2forkhead box A20.027
her11hairy-related 110.027
tac1tachykinin 10.026
her1hairy-related 10.026
spry1sprouty homolog 1 (Drosophila)0.026
irx1airoquois homeobox protein 1, a0.025
colec11collectin sub-family member 110.025
foxi1forkhead box I10.025
vcanaversican a0.024
pld1aphospholipase D1a0.024
cdh5cadherin 50.024
egr2aearly growth response 2a0.023
sox10SRY-box containing gene 100.023
fzd10frizzled homolog 100.023
foxn4forkhead box N40.023
dbx1bdeveloping brain homeobox 1b0.023
pax8paired box gene 80.023
ret1receptor tyrosine kinase0.023
fancd2Fanconi anemia, complementation group D20.022
wnt2bawingless-type MMTV integration site family, member 2Ba0.022
wu:fb01h12wu:fb01h120.022
ift52intraflagellar transport protein 520.022
wnt5bwingless-type MMTV integration site family, member 5b0.022
alx4aaristaless-like homeobox 4a0.021
tbx2bT-box 2b0.021
foxi3bforkhead box I3b0.021
vegfabvascular endothelial growth factor Ab0.020
lef1lymphocyte enhancer binding factor 10.020
lhx1bLIM homeobox 1b0.020
eng2bengrailed 2b0.020
neurod6bneurogenic differentiation 6b0.020
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Lhx1LIM homeobox protein 10.910
Pax2paired box gene 20.878
Fgfr2fibroblast growth factor receptor 20.854
Emx2empty spiracles homolog 2 (Drosophila)0.793
Shhsonic hedgehog0.762
Fgf8fibroblast growth factor 80.744
Pitx2paired-like homeodomain transcription factor 20.690
Otx2orthodenticle homolog 2 (Drosophila)0.622
Pax3paired box gene 30.591
Gli3GLI-Kruppel family member GLI30.487
Tbx1T-box 10.460
Rargretinoic acid receptor, gamma0.389
Foxc1forkhead box C10.376
Gata4GATA binding protein 40.333
Wt1Wilms tumor 1 homolog0.279
Hand1heart and neural crest derivatives expressed transcript 10.264
Gbx2gastrulation brain homeobox 20.219
Hoxa1homeobox A10.208
Hand2heart and neural crest derivatives expressed transcript 20.204
Msx1homeobox, msh-like 10.204
Foxc2forkhead box C20.142
Gdnfglial cell line derived neurotrophic factor0.141
Wnt3awingless-related MMTV integration site 3A0.130
Rxraretinoid X receptor alpha0.111
Pax6paired box gene 60.110
Dlx5distal-less homeobox 50.108
Smosmoothened homolog (Drosophila)0.106
Ednraendothelin receptor type A0.106
Tbrachyury0.103
Nr5a1nuclear receptor subfamily 5, group A, member 10.102
Tgfb2transforming growth factor, beta 20.092
Emx1empty spiracles homolog 1 (Drosophila)0.090
Bmp4bone morphogenetic protein 40.088
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.086
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.085
Hes1hairy and enhancer of split 1 (Drosophila)0.078
Eya1eyes absent 1 homolog (Drosophila)0.074
Lmx1aLIM homeobox transcription factor 1 alpha0.073
Fgf10fibroblast growth factor 100.072
Lef1lymphoid enhancer binding factor 10.071
Lhx3LIM homeobox protein 30.071
Foxf1aforkhead box F1a0.071
Fgfr1fibroblast growth factor receptor 10.068
Prrx2paired related homeobox 20.066
Sox9SRY-box containing gene 90.066
Wnt4wingless-related MMTV integration site 40.066
Isl1ISL1 transcription factor, LIM/homeodomain0.065
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.060
Rarbretinoic acid receptor, beta0.059
Lhx9LIM homeobox protein 90.054
Notch1Notch gene homolog 1 (Drosophila)0.053
Dkk1dickkopf homolog 1 (Xenopus laevis)0.052
Aldh1a2aldehyde dehydrogenase family 1, subfamily A20.048
Wnt1wingless-related MMTV integration site 10.046
Jag1jagged 10.045
Tcfap2atranscription factor AP-2, alpha0.044
Otx1orthodenticle homolog 1 (Drosophila)0.044
Bmp7bone morphogenetic protein 70.042
Tbx3T-box 30.042
Nodalnodal0.040
Chd7chromodomain helicase DNA binding protein 70.038
Bnc1basonuclin 10.038
Pax8paired box gene 80.036
Gata6GATA binding protein 60.036
Gli2GLI-Kruppel family member GLI20.034
Mesp1mesoderm posterior 10.034
Fgf3fibroblast growth factor 30.034
Acvr1activin A receptor, type 10.033
Bicc1bicaudal C homolog 1 (Drosophila)0.033
Ror2receptor tyrosine kinase-like orphan receptor 20.033
Tbx2T-box 20.032
Hes5hairy and enhancer of split 5 (Drosophila)0.031
Foxg1forkhead box G10.029
Lmx1bLIM homeobox transcription factor 1 beta0.029
Twist2twist homolog 2 (Drosophila)0.028
Gscgoosecoid homeobox0.026
Onecut1one cut domain, family member 10.024
Rararetinoic acid receptor, alpha0.024
Dll1delta-like 1 (Drosophila)0.024
Chrdchordin0.023
Invsinversin0.022
Pou3f3POU domain, class 3, transcription factor 30.020
Pitx1paired-like homeodomain transcription factor 10.020
Prrx1paired related homeobox 10.020
Nkx1-2NK1 transcription factor related, locus 2 (Drosophila)0.019
Hoxa2homeobox A20.019
Hmx3H6 homeobox 30.019
Vegfavascular endothelial growth factor A0.019
En1engrailed 10.019
Mks1Meckel syndrome, type 10.018
Nognoggin0.018
Alx4aristaless-like homeobox 40.018
Foxf2forkhead box F20.018
Dlx1distal-less homeobox 10.017
Wnt6wingless-related MMTV integration site 60.017
Hoxa11homeobox A110.016
Hoxd11homeobox D110.016
Fgf18fibroblast growth factor 180.016
Lhx5LIM homeobox protein 50.016
Hoxa3homeobox A30.016
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gata3GATA binding protein 30.452
Klk1c10T-kininogenase0.146
Lhx1LIM homeobox 10.133
Cacna1scalcium channel, voltage-dependent, L type, alpha 1S subunit0.083
Foxs1forkhead box S10.083
Gjd2gap junction protein, delta 20.072
Tal1T-cell acute lymphocytic leukemia 10.063
Kif1ckinesin family member 1C0.061
Sod3superoxide dismutase 3, extracellular0.053
Sftpbsurfactant protein B0.053
Ngfrnerve growth factor receptor (TNFR superfamily, member 16)0.051
Fut4fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)0.049
Onecut1one cut homeobox 10.048
RT1-DOaRT1 class II, locus DOa0.047
Erbb4v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)0.046
Kcnk3potassium channel, subfamily K, member 30.042
Add2adducin 2 (beta)0.042
Gastgastrin0.042
Ntrk1neurotrophic tyrosine kinase, receptor, type 10.038
Kcnc3potassium voltage gated channel, Shaw-related subfamily, member 30.037
Shox2short stature homeobox 20.036
Pdcphosducin0.036
Ascl1achaete-scute complex homolog 1 (Drosophila)0.034
Olr1523olfactory receptor 15230.032
Akap14A kinase (PRKA) anchor protein 140.026
Lef1lymphoid enhancer binding factor 10.025
Gpx5glutathione peroxidase 50.025
Hlfhepatic leukemia factor0.023
Colec12collectin sub-family member 120.023
Alx1ALX homeobox 10.022
Ambpalpha-1-microglobulin/bikunin precursor0.022
Fmodfibromodulin0.022
Brca1breast cancer 10.022
Ebf1early B-cell factor 10.021
Sox12SRY (sex determining region Y)-box 120.021
Kif27kinesin family member 270.021
Pdpnpodoplanin0.020
Fam63bfamily with sequence similarity 63, member B0.020
Col9a1collagen, type IX, alpha 10.020
Dnah2dynein, axonemal, heavy chain 20.020
Fgf18fibroblast growth factor 180.020
Pcdhb12protocadherin beta 120.020
Znf76zinc finger protein 76 (expressed in testis)0.020
Tpothyroid peroxidase0.019
Hoxc4homeo box C40.019
Phexphosphate regulating endopeptidase homolog, X-linked0.019
Aebp1AE binding protein 10.018
Phox2apaired-like homeobox 2a0.017
Loxl1lysyl oxidase-like 10.016
Serpinb3aserine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A0.016
Gpc3glypican 30.016
Fhl3four and a half LIM domains 30.016
Klf13Kruppel-like factor 130.015
Prl8a2prolactin family 8, subfamily a, member 20.015
Sdk2sidekick homolog 2 (chicken)0.015
Scnn1bsodium channel, nonvoltage-gated 1, beta0.015
Bmp4bone morphogenetic protein 40.014
Il1r1interleukin 1 receptor, type I0.014
Pdha2pyruvate dehydrogenase (lipoamide) alpha 20.014
Fbxo16F-box protein 160.013
Snai1snail homolog 1 (Drosophila)0.013
Kcnab3potassium voltage-gated channel, shaker-related subfamily, beta member 30.013
Olr825olfactory receptor 8250.013
Higd1bHIG1 hypoxia inducible domain family, member 1B0.013
Sytl1synaptotagmin-like 10.012
Ptpn14protein tyrosine phosphatase, non-receptor type 140.012
Sctrsecretin receptor0.012
Dcaf17DDB1 and CUL4 associated factor 170.012
Crygecrystallin, gamma E0.012
Atp4bATPase, H+/K+ exchanging, beta polypeptide0.012
C1qtnf5C1q and tumor necrosis factor related protein 50.012
WtipWilms tumor 1 interacting protein0.012
Cited1Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 10.012
Cngb1cyclic nucleotide gated channel beta 10.012
Bcl2l14Bcl2-like 14 (apoptosis facilitator)0.012
LOC245710PSD-95 binding protein0.012
Rit2Ras-like without CAAX 20.012
Gdf11growth differentiation factor 110.011
St3gal3ST3 beta-galactoside alpha-2,3-sialyltransferase 30.011
Col17a1collagen, type XVII, alpha 10.011
Bex4brain expressed, X-linked 40.011
Sgtbsmall glutamine-rich tetratricopeptide repeat (TPR)-containing, beta0.011
Tcfap2btranscription factor AP-2 beta0.011
Tnrtenascin R0.011
Fzd2frizzled homolog 2 (Drosophila)0.010
Zmat4zinc finger, matrin type 40.010
Accn2amiloride-sensitive cation channel 2, neuronal0.010
UncxUNC homeobox0.010
Gng8guanine nucleotide binding protein (G protein), gamma 80.010
Sox17SRY (sex determining region Y)-box 170.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism