The network for 'phagocytosis recognition' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

phagocytosis recognition

The initial step in phagocytosis involving adhesion to bacteria, immune complexes and other particulate matter, or an apoptotic cell and based on recognition of factors such as bacterial cell wall components, opsonins like complement and antibody or protein receptors and lipids like phosphatidyl serine, and leading to intracellular signaling in the phagocytosing cell.

NameDescriptionProbabilityFunc Analog Organism
SYKspleen tyrosine kinase0.997
KLRD1killer cell lectin-like receptor subfamily D, member 10.994
KLRC3killer cell lectin-like receptor subfamily C, member 30.917
U2AF1U2 small nuclear RNA auxiliary factor 10.877
PTPN6protein tyrosine phosphatase, non-receptor type 60.809
LYNv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.789
KLRC2killer cell lectin-like receptor subfamily C, member 20.752
LCKlymphocyte-specific protein tyrosine kinase0.733
GZMKgranzyme K (granzyme 3; tryptase II)0.696
TYROBPTYRO protein tyrosine kinase binding protein0.654
ZCCHC17zinc finger, CCHC domain containing 170.640
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.582
BRD4bromodomain containing 40.562
KLRK1killer cell lectin-like receptor subfamily K, member 10.561
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.493
ITKIL2-inducible T-cell kinase0.490
KLRB1killer cell lectin-like receptor subfamily B, member 10.459
INPP5Dinositol polyphosphate-5-phosphatase, 145kDa0.452
CSF2RBcolony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)0.445
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.442
GZMBgranzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)0.427
PRF1perforin 1 (pore forming protein)0.426
CD33CD33 molecule0.412
PILRApaired immunoglobin-like type 2 receptor alpha0.399
CLEC4AC-type lectin domain family 4, member A0.379
KLRC1killer cell lectin-like receptor subfamily C, member 10.370
CD163CD163 molecule0.337
PECAM1platelet/endothelial cell adhesion molecule0.281
GZMAgranzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)0.273
KLRG1killer cell lectin-like receptor subfamily G, member 10.266
IFNGinterferon, gamma0.246
GPR65G protein-coupled receptor 650.243
CD3ECD3e molecule, epsilon (CD3-TCR complex)0.227
PRPF38APRP38 pre-mRNA processing factor 38 (yeast) domain containing A0.222
EPORerythropoietin receptor0.216
CCR5chemokine (C-C motif) receptor 50.209
FCGR2CFc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)0.206
UBASH3Bubiquitin associated and SH3 domain containing B0.167
FASLGFas ligand (TNF superfamily, member 6)0.149
MS4A6Amembrane-spanning 4-domains, subfamily A, member 6A0.144
CCR1chemokine (C-C motif) receptor 10.129
KLRC4killer cell lectin-like receptor subfamily C, member 40.125
ITGAMintegrin, alpha M (complement component 3 receptor 3 subunit)0.121
CCR2chemokine (C-C motif) receptor 20.117
CD84CD84 molecule0.109
FGL2fibrinogen-like 20.109
GPR171G protein-coupled receptor 1710.105
CXCR6chemokine (C-X-C motif) receptor 60.104
LAIR1leukocyte-associated immunoglobulin-like receptor 10.096
CCL4chemokine (C-C motif) ligand 40.096
F13A1coagulation factor XIII, A1 polypeptide0.094
CD160CD160 molecule0.094
CD2CD2 molecule0.091
IGSF6immunoglobulin superfamily, member 60.088
KLRF1killer cell lectin-like receptor subfamily F, member 10.085
LEPROTL1leptin receptor overlapping transcript-like 10.085
CYBBcytochrome b-245, beta polypeptide0.083
CXCL9chemokine (C-X-C motif) ligand 90.082
GIMAP4GTPase, IMAP family member 40.071
SH3BP2SH3-domain binding protein 20.070
CD53CD53 molecule0.066
RNASE2ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)0.065
CR1complement component (3b/4b) receptor 1 (Knops blood group)0.063
XCL2chemokine (C motif) ligand 20.063
CD93CD93 molecule0.062
EMR1egf-like module containing, mucin-like, hormone receptor-like 10.062
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.062
NKG7natural killer cell group 7 sequence0.059
CD3GCD3g molecule, gamma (CD3-TCR complex)0.058
FCGR2BFc fragment of IgG, low affinity IIb, receptor (CD32)0.055
CEACAM1carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)0.055
P2RY13purinergic receptor P2Y, G-protein coupled, 130.055
FYBFYN binding protein0.055
GZMHgranzyme H (cathepsin G-like 2, protein h-CCPX)0.054
CBLCas-Br-M (murine) ecotropic retroviral transforming sequence0.050
LILRA1leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 10.050
KIR3DL2killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 20.046
IL18RAPinterleukin 18 receptor accessory protein0.046
CLEC5AC-type lectin domain family 5, member A0.046
TLR2toll-like receptor 20.046
VSIG4V-set and immunoglobulin domain containing 40.046
ADORA3adenosine A3 receptor0.044
CD1CCD1c molecule0.042
TFECtranscription factor EC0.042
KIR2DL3killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 30.042
FPR3formyl peptide receptor 30.042
MSR1macrophage scavenger receptor 10.041
IL4Rinterleukin 4 receptor0.041
CD96CD96 molecule0.041
CSF1Rcolony stimulating factor 1 receptor0.040
SIGLEC7sialic acid binding Ig-like lectin 70.038
CSF2RAcolony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)0.038
PYHIN1pyrin and HIN domain family, member 10.038
GRAP2GRB2-related adaptor protein 20.038
CD226CD226 molecule0.037
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.036
SRSF4serine/arginine-rich splicing factor 40.035
MNDAmyeloid cell nuclear differentiation antigen0.035
CD28CD28 molecule0.034
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
CG9990CG9990 gene product from transcript CG9990-RA0.101
Lsd-2Lipid storage droplet-20.096
Npc2gNiemann-Pick type C-2g0.091
MED4Mediator complex subunit 40.063
CG3305CG3305 gene product from transcript CG3305-RA0.054
inaDinactivation no afterpotential D0.049
CG11073CG11073 gene product from transcript CG11073-RB0.043
plexBplexin B0.040
CG4822CG4822 gene product from transcript CG4822-RB0.038
CG14526CG14526 gene product from transcript CG14526-RB0.035
CG10743CG10743 gene product from transcript CG10743-RB0.030
CG6490CG6490 gene product from transcript CG6490-RB0.029
CG8602CG8602 gene product from transcript CG8602-RA0.027
CG3164CG3164 gene product from transcript CG3164-RA0.025
Best1Bestrophin 10.024
CG18249CG18249 gene product from transcript CG18249-RB0.022
CG15828CG15828 gene product from transcript CG15828-RC0.021
CG13784CG13784 gene product from transcript CG13784-RC0.021
CG15917CG15917 gene product from transcript CG15917-RA0.020
CG9628CG9628 gene product from transcript CG9628-RA0.019
CG31778CG31778 gene product from transcript CG31778-RA0.019
CG5853CG5853 gene product from transcript CG5853-RA0.019
nimC4nimrod C40.018
CG5004CG5004 gene product from transcript CG5004-RA0.018
CG14933CG14933 gene product from transcript CG14933-RA0.016
CG5493CG5493 gene product from transcript CG5493-RA0.015
Rh6Rhodopsin 60.015
GNBP3Gram-negative bacteria binding protein 30.015
CG7997CG7997 gene product from transcript CG7997-RB0.015
CG6051CG6051 gene product from transcript CG6051-RB0.015
CG10026CG10026 gene product from transcript CG10026-RA0.014
CG13526CG13526 gene product from transcript CG13526-RA0.014
CG4607CG4607 gene product from transcript CG4607-RA0.014
kat-60L1katanin p60-like 10.014
CG4306CG4306 gene product from transcript CG4306-RA0.013
tadrtorn and diminished rhabdomeres0.013
CG13636CG13636 gene product from transcript CG13636-RB0.012
AtetABC transporter expressed in trachea0.012
CG32091CG32091 gene product from transcript CG32091-RB0.012
wtrwCG31284 gene product from transcript CG31284-RB0.012
CG17646CG17646 gene product from transcript CG17646-RB0.012
Edem2CG5682 gene product from transcript CG5682-RA0.012
Arr2Arrestin 20.011
CG14216CG14216 gene product from transcript CG14216-RA0.011
CG7675CG7675 gene product from transcript CG7675-RC0.011
Dhap-atDihydroxyacetone phosphate acyltransferase0.011
CG8317CG8317 gene product from transcript CG8317-RA0.011
CG5326CG5326 gene product from transcript CG5326-RA0.011
AcerAngiotensin-converting enzyme-related0.011
CG9444CG9444 gene product from transcript CG9444-RA0.011
CG16926CG16926 gene product from transcript CG16926-RA0.011
CG11147CG11147 gene product from transcript CG11147-RA0.011
mthl1methuselah-like 10.010
CG9801CG9801 gene product from transcript CG9801-RC0.010
CG33970CG33970 gene product from transcript CG33970-RA0.010
CG7852CG7852 gene product from transcript CG7852-RA0.010
CG6053CG6053 gene product from transcript CG6053-RB0.010
Neu3CG7649 gene product from transcript CG7649-RC0.010
CG8654CG8654 gene product from transcript CG8654-RA0.010
BmcpCG7314 gene product from transcript CG7314-RB0.010
CG11880CG11880 gene product from transcript CG11880-RA0.010
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Klra9killer cell lectin-like receptor subfamily A, member 90.421
Clec4dC-type lectin domain family 4, member d0.333
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.285
Ncr1natural cytotoxicity triggering receptor 10.144
Clec4a2C-type lectin domain family 4, member a20.124
Clec4eC-type lectin domain family 4, member e0.119
Msr1macrophage scavenger receptor 10.107
Clec4nC-type lectin domain family 4, member n0.094
Klrk1killer cell lectin-like receptor subfamily K, member 10.075
Fpr2formyl peptide receptor 20.064
Ccr1chemokine (C-C motif) receptor 10.061
Klra2killer cell lectin-like receptor, subfamily A, member 20.060
Plxnd1plexin D10.057
Ear2eosinophil-associated, ribonuclease A family, member 20.048
Gzmagranzyme A0.046
Cr2complement receptor 20.040
Emr1EGF-like module containing, mucin-like, hormone receptor-like sequence 10.038
C3ar1complement component 3a receptor 10.038
Cd209bCD209b antigen0.036
FcrlaFc receptor-like A0.035
Fpr1formyl peptide receptor 10.034
Klrd1killer cell lectin-like receptor, subfamily D, member 10.034
Ms4a6dmembrane-spanning 4-domains, subfamily A, member 6D0.034
Ms4a1membrane-spanning 4-domains, subfamily A, member 10.033
Ccl6chemokine (C-C motif) ligand 60.033
Klrc1killer cell lectin-like receptor subfamily C, member 10.032
Il18rapinterleukin 18 receptor accessory protein0.030
Cybbcytochrome b-245, beta polypeptide0.029
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.029
Pilrb1paired immunoglobin-like type 2 receptor beta 10.029
Ccr5chemokine (C-C motif) receptor 50.026
Pf4platelet factor 40.026
AF251705cDNA sequence AF2517050.025
Cd209dCD209d antigen0.024
Lair1leukocyte-associated Ig-like receptor 10.024
BlkB lymphoid kinase0.024
Ccl9chemokine (C-C motif) ligand 90.023
Cd209aCD209a antigen0.022
Clec7aC-type lectin domain family 7, member a0.022
Emr4EGF-like module containing, mucin-like, hormone receptor-like sequence 40.021
Mmp8matrix metallopeptidase 80.021
Il1binterleukin 1 beta0.020
Igkimmunoglobulin kappa chain complex0.019
Pilrapaired immunoglobin-like type 2 receptor alpha0.019
MefvMediterranean fever0.018
Ccl24chemokine (C-C motif) ligand 240.018
Chi3l3chitinase 3-like 30.017
Mpeg1macrophage expressed gene 10.017
Clec4b1C-type lectin domain family 4, member b10.017
Cd5lCD5 antigen-like0.016
S100a8S100 calcium binding protein A8 (calgranulin A)0.016
Klrb1bkiller cell lectin-like receptor subfamily B member 1B0.016
Fcgr4Fc receptor, IgG, low affinity IV0.016
Aoahacyloxyacyl hydrolase0.015
Igsf6immunoglobulin superfamily, member 60.015
Tcfectranscription factor EC0.014
Mgl2macrophage galactose N-acetyl-galactosamine specific lectin 20.014
Ccr3chemokine (C-C motif) receptor 30.014
Lilrb4leukocyte immunoglobulin-like receptor, subfamily B, member 40.014
Cfhcomplement component factor h0.014
Tlr8toll-like receptor 80.013
Mmp12matrix metallopeptidase 120.013
Rgs18regulator of G-protein signaling 180.013
Cpa3carboxypeptidase A3, mast cell0.013
Klra17killer cell lectin-like receptor, subfamily A, member 170.013
Mrc1mannose receptor, C type 10.013
Siglecesialic acid binding Ig-like lectin E0.012
Cd300ldCD300 molecule-like family member d0.012
F13a1coagulation factor XIII, A1 subunit0.012
Cd14CD14 antigen0.012
Ms4a7membrane-spanning 4-domains, subfamily A, member 70.012
Cd33CD33 antigen0.012
Slc11a1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.012
Pax5paired box gene 50.012
Klrb1ckiller cell lectin-like receptor subfamily B member 1C0.012
Flt3FMS-like tyrosine kinase 30.012
Klra7killer cell lectin-like receptor, subfamily A, member 70.012
Trem3triggering receptor expressed on myeloid cells 30.012
Klra5killer cell lectin-like receptor, subfamily A, member 50.012
Sirpb1asignal-regulatory protein beta 1A0.011
Apoeapolipoprotein E0.011
Gdaguanine deaminase0.011
Cma1chymase 1, mast cell0.011
Slamf7SLAM family member 70.011
S100a9S100 calcium binding protein A9 (calgranulin B)0.011
Gzmkgranzyme K0.011
Csf1rcolony stimulating factor 1 receptor0.010
Gcet2germinal center expressed transcript 20.010
Niacr1niacin receptor 10.010
Igjimmunoglobulin joining chain0.010
Cd300aCD300A antigen0.010
Iglimmunoglobulin lambda chain complex0.010
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.015
Cd74Cd74 molecule, major histocompatibility complex, class II invariant chain0.014
C1qacomplement component 1, q subcomponent, A chain0.013
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism