The network for 'acrosomal vesicle exocytosis' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

acrosomal vesicle exocytosis

The release of intracellular molecules contained within the acrosomal granule by fusion of the vesicle with the plasma membrane of the oocyte, requiring calcium ions.

NameDescriptionProbabilityFunc Analog Organism
APPBP2amyloid beta precursor protein (cytoplasmic tail) binding protein 20.897
SNAP25synaptosomal-associated protein, 25kDa0.557
GOLM1golgi membrane protein 10.193
NINLninein-like0.125
STX1Asyntaxin 1A (brain)0.039
NFYAnuclear transcription factor Y, alpha0.039
STON2stonin 20.038
TRPV1transient receptor potential cation channel, subfamily V, member 10.032
SEZ6Lseizure related 6 homolog (mouse)-like0.030
CHGAchromogranin A (parathyroid secretory protein 1)0.029
INAinternexin neuronal intermediate filament protein, alpha0.029
ATP13A2ATPase type 13A20.028
TSC22D4TSC22 domain family, member 40.026
SRCIN1SRC kinase signaling inhibitor 10.021
VAMP2vesicle-associated membrane protein 2 (synaptobrevin 2)0.019
CPLX2complexin 20.017
GJA5gap junction protein, alpha 5, 40kDa0.017
PRRT2proline-rich transmembrane protein 20.017
NECAB2N-terminal EF-hand calcium binding protein 20.016
SYN1synapsin I0.016
SYN2synapsin II0.016
NRXN1neurexin 10.016
ITSN1intersectin 1 (SH3 domain protein)0.015
SPTBN4spectrin, beta, non-erythrocytic 40.014
KCNF1potassium voltage-gated channel, subfamily F, member 10.014
ADRA2Cadrenergic, alpha-2C-, receptor0.014
ELAVL4ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)0.014
LHX4LIM homeobox 40.014
CARD11caspase recruitment domain family, member 110.014
CACNB4calcium channel, voltage-dependent, beta 4 subunit0.014
KIAA1045KIAA10450.014
CACNG7calcium channel, voltage-dependent, gamma subunit 70.014
PNPLA5patatin-like phospholipase domain containing 50.013
SNCBsynuclein, beta0.013
VGFVGF nerve growth factor inducible0.013
CHRNB2cholinergic receptor, nicotinic, beta 2 (neuronal)0.013
CACNG4calcium channel, voltage-dependent, gamma subunit 40.012
RBP2retinol binding protein 2, cellular0.012
SPTBN2spectrin, beta, non-erythrocytic 20.012
CELF4CUGBP, Elav-like family member 40.012
SYPsynaptophysin0.012
CNNM1cyclin M10.012
HRH3histamine receptor H30.012
FAM123Cfamily with sequence similarity 123C0.012
SLC9A5solute carrier family 9 (sodium/hydrogen exchanger), member 50.012
NPTX1neuronal pentraxin I0.012
GPR26G protein-coupled receptor 260.012
ARHGDIGRho GDP dissociation inhibitor (GDI) gamma0.011
GSG1LGSG1-like0.011
SEZ6seizure related 6 homolog (mouse)0.011
STAC2SH3 and cysteine rich domain 20.011
IGLON5IgLON family member 50.011
SRRM3serine/arginine repetitive matrix 30.011
DLGAP3discs, large (Drosophila) homolog-associated protein 30.011
SLC17A6solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 60.011
TTC9Btetratricopeptide repeat domain 9B0.011
SLC30A3solute carrier family 30 (zinc transporter), member 30.011
MUL1mitochondrial E3 ubiquitin protein ligase 10.011
HMP19HMP19 protein0.011
CRHR1corticotropin releasing hormone receptor 10.011
KIAA1267KIAA12670.011
ACER1alkaline ceramidase 10.011
TMEM145transmembrane protein 1450.011
EID3EP300 interacting inhibitor of differentiation 30.011
ANKRD24ankyrin repeat domain 240.011
KCNE3potassium voltage-gated channel, Isk-related family, member 30.011
CST9cystatin 9 (testatin)0.011
CA7carbonic anhydrase VII0.011
LMTK3lemur tyrosine kinase 30.011
CA10carbonic anhydrase X0.010
C20orf70chromosome 20 open reading frame 700.010
PCSK2proprotein convertase subtilisin/kexin type 20.010
PTCHD2patched domain containing 20.010
SLC25A47solute carrier family 25, member 470.010
KIRREL3kin of IRRE like 3 (Drosophila)0.010
UNC13Aunc-13 homolog A (C. elegans)0.010
PCLOpiccolo (presynaptic cytomatrix protein)0.010
TMEM59Ltransmembrane protein 59-like0.010
KCNJ4potassium inwardly-rectifying channel, subfamily J, member 40.010
EXOC3L1exocyst complex component 3-like 10.010
PTPN5protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)0.010
CALB1calbindin 1, 28kDa0.010
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Kcnj6potassium inwardly-rectifying channel, subfamily J, member 60.032
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.021
Oprm1opioid receptor, mu 10.012
Gsx1GS homeobox 10.011
Adra2cadrenergic receptor, alpha 2c0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism