The network for 'antibacterial humoral response' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

antibacterial humoral response

An immune response against bacteria mediated through a body fluid. Examples of this process are the antibacterial humoral responses in Mus musculus and Drosophila melanogaster.

NameDescriptionProbabilityFunc Analog Organism
HIST1H2BFhistone cluster 1, H2bf0.996
HIST1H2BEhistone cluster 1, H2be0.991
HIST1H2AChistone cluster 1, H2ac0.986
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.971
HIST1H2BDhistone cluster 1, H2bd0.966
HIST2H2AA4histone cluster 2, H2aa40.914
HIST1H2BHhistone cluster 1, H2bh0.902
HIST1H1Chistone cluster 1, H1c0.886
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.831
HIST1H2BIhistone cluster 1, H2bi0.825
HIST1H2BChistone cluster 1, H2bc0.804
NFKB1nuclear factor of kappa light polypeptide gene enhancer in B-cells 10.799
HIST1H3Dhistone cluster 1, H3d0.796
NFKBIAnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.745
NFKBIBnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta0.627
MAPK8mitogen-activated protein kinase 80.584
HIST1H2BKhistone cluster 1, H2bk0.531
RELBv-rel reticuloendotheliosis viral oncogene homolog B0.495
IKBKGinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.494
HIST1H2BGhistone cluster 1, H2bg0.426
MAP2K4mitogen-activated protein kinase kinase 40.392
ARRB1arrestin, beta 10.386
HIST1H2AEhistone cluster 1, H2ae0.386
HIST1H2AJhistone cluster 1, H2aj0.381
NFKB2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)0.341
ANGangiogenin, ribonuclease, RNase A family, 50.255
IKBKBinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta0.220
RNASE4ribonuclease, RNase A family, 40.204
NFKBIEnuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon0.204
NLRC4NLR family, CARD domain containing 40.164
JUNjun proto-oncogene0.159
MAP3K8mitogen-activated protein kinase kinase kinase 80.137
CRADDCASP2 and RIPK1 domain containing adaptor with death domain0.128
HIST1H3Hhistone cluster 1, H3h0.107
RPL41ribosomal protein L410.098
CHUKconserved helix-loop-helix ubiquitous kinase0.094
HIST1H2AMhistone cluster 1, H2am0.079
RPS27ribosomal protein S270.071
MAP3K14mitogen-activated protein kinase kinase kinase 140.064
MAP3K1mitogen-activated protein kinase kinase kinase 10.060
TPT1tumor protein, translationally-controlled 10.044
RPS29ribosomal protein S290.042
HIST1H2AGhistone cluster 1, H2ag0.040
HIST1H4Hhistone cluster 1, H4h0.038
MZB1marginal zone B and B1 cell-specific protein0.037
LCN2lipocalin 20.034
CASP10caspase 10, apoptosis-related cysteine peptidase0.034
LRDDleucine-rich repeats and death domain containing0.033
CTSGcathepsin G0.028
HIST1H2ALhistone cluster 1, H2al0.028
HIST1H3Ghistone cluster 1, H3g0.027
TNIP2TNFAIP3 interacting protein 20.026
CAMPcathelicidin antimicrobial peptide0.026
BPIbactericidal/permeability-increasing protein0.025
ELANEelastase, neutrophil expressed0.025
RNASE3ribonuclease, RNase A family, 30.024
TAB3TGF-beta activated kinase 1/MAP3K7 binding protein 30.024
IGL@immunoglobulin lambda locus0.023
FKBP5FK506 binding protein 50.023
RIPK2receptor-interacting serine-threonine kinase 20.023
ATF2activating transcription factor 20.023
GSK3Bglycogen synthase kinase 3 beta0.022
SERPINB1serpin peptidase inhibitor, clade B (ovalbumin), member 10.022
ELF4E74-like factor 4 (ets domain transcription factor)0.021
HIST1H2BOhistone cluster 1, H2bo0.020
HIST1H2BMhistone cluster 1, H2bm0.019
RPL34ribosomal protein L340.019
MTHFD1Lmethylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like0.019
MMP8matrix metallopeptidase 8 (neutrophil collagenase)0.019
AZU1azurocidin 10.018
IGF2insulin-like growth factor 2 (somatomedin A)0.018
ATF3activating transcription factor 30.018
RAI1retinoic acid induced 10.018
ARRB2arrestin, beta 20.017
ITGB1BP1integrin beta 1 binding protein 10.017
IGK@immunoglobulin kappa locus0.016
DEFA4defensin, alpha 4, corticostatin0.016
HIST1H2AIhistone cluster 1, H2ai0.016
CD19CD19 molecule0.016
PGLYRP1peptidoglycan recognition protein 10.016
RNASE2ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)0.016
TCN1transcobalamin I (vitamin B12 binding protein, R binder family)0.016
HIST1H2BBhistone cluster 1, H2bb0.015
HIST1H2BJhistone cluster 1, H2bj0.015
MAPK8IP1mitogen-activated protein kinase 8 interacting protein 10.015
SIN3ASIN3 homolog A, transcription regulator (yeast)0.014
FPR2formyl peptide receptor 20.014
DUSP1dual specificity phosphatase 10.014
PPP6Cprotein phosphatase 6, catalytic subunit0.014
IKBKEinhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon0.014
PRKACAprotein kinase, cAMP-dependent, catalytic, alpha0.014
IGJimmunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides0.014
BCL3B-cell CLL/lymphoma 30.014
TNFRSF17tumor necrosis factor receptor superfamily, member 170.014
MS4A3membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific)0.013
RPL37Aribosomal protein L37a0.013
HIST1H4Ehistone cluster 1, H4e0.013
HIST2H2BEhistone cluster 2, H2be0.013
RPS15ribosomal protein S150.013
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
LOC557072caspase recruitment domain-containing protein 11-like0.221
nod1nucleotide-binding oligomerization domain containing 10.201
pycardPYD and CARD domain containing0.043
slc4a4bsolute carrier family 4, sodium bicarbonate cotransporter, member 4b0.039
mpllmyeloproliferative leukemia virus oncogene, like0.039
comtacatechol-O-methyltransferase a0.034
ef1aelongation factor 1-alpha0.030
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.025
lndc1ly6/neurotoxin domain containing 10.025
fbp1bfructose-1,6-bisphosphatase 1b0.025
LOC100000934hypothetical protein LOC1000009340.025
card14caspase recruitment domain family, member 140.025
tnfbtumor necrosis factor b (TNF superfamily, member 2)0.024
card9caspase recruitment domain family, member 90.022
bhmtbetaine-homocysteine methyltransferase0.022
slc4a1bsolute carrier family 4, anion exchanger, member 1b0.022
kng1kininogen 10.021
gipgastric inhibitory polypeptide0.021
lrmplymphoid-restricted membrane protein0.021
col10a1collagen, type X, alpha 10.020
ripk2receptor-interacting serine-threonine kinase 20.020
satb2SATB homeobox 20.018
LOC566708FL cytokine receptor-like0.018
trpv6transient receptor potential cation channel, subfamily V, member 60.016
c1qccomplement component 1, q subcomponent, C chain0.016
nitr3cnovel immune-type receptor 3c0.016
LOC100534776toll-like receptor 7-like0.015
itih2inter-alpha (globulin) inhibitor H20.015
caspacaspase a0.015
sass6spindle assembly 6 homolog (C. elegans)0.015
plk3polo-like kinase 3 (Drosophila)0.015
ifnphi1interferon phi 10.014
eporerythropoietin receptor0.014
ptpn11aprotein tyrosine phosphatase, non-receptor type 11, a0.014
rp2retinitis pigmentosa 2 (X-linked recessive)0.013
mapk7mitogen-activated protein kinase 70.013
casrlcalcium-sensing receptor, like0.013
pdpk1a3-phosphoinositide dependent protein kinase-1a0.013
ikbkginhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma0.013
il6rinterleukin 6 receptor0.013
stc1lstanniocalcin 1, like0.013
ctsbacathepsin B, a0.012
rhagRhesus blood group-associated glycoprotein0.012
slc7a6solute carrier family 7 (cationic amino acid transporter, y+ system), member 60.012
rhcgbRhesus blood group, C glycoprotein b0.011
tlr8btoll-like receptor 8b0.011
nos2bnitric oxide synthase 2b, inducible0.011
aplp2amyloid beta (A4) precursor-like protein 20.011
snapc1bsmall nuclear RNA activating complex, polypeptide 1b0.011
nr3c2nuclear receptor subfamily 3, group C, member 20.011
itga2bintegrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41B)0.011
nos2anitric oxide synthase 2a, inducible0.011
il6stinterleukin 6 signal transducer0.011
acvr2aactivin receptor IIa0.010
slc14a2solute carrier family 14 (urea transporter), member 20.010
xylt1xylosyltransferase 10.010
stau2staufen, RNA binding protein, homolog 2 (Drosophila)0.010
cd40CD40 antigen0.010
wnt9bwingless-type MMTV integration site family, member 9B0.010
slc12a10.2solute carrier family 12 (sodium/potassium/chloride transporters), member 10.20.010
glrx5glutaredoxin 5 homolog (S. cerevisiae)0.010
rplp1ribosomal protein, large, P10.010
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
PGRP-LCPeptidoglycan recognition protein LC1.000
DptBDiptericin B0.999
grassGram-positive Specific Serine protease0.994
ird5immune response deficient 50.991
Spn27ASerpin 27A0.990
CG15065CG15065 gene product from transcript CG15065-RA0.985
CG13422CG13422 gene product from transcript CG13422-RA0.985
PGRP-SDCG7496 gene product from transcript CG7496-RA0.980
DreddDeath related ced-3/Nedd2-like protein0.978
IM1Immune induced molecule 10.971
IrcImmune-regulated catalase0.963
CG5791CG5791 gene product from transcript CG5791-RA0.959
PGRP-SAPeptidoglycan recognition protein SA0.952
SPESpatzle-Processing Enzyme0.942
IM10Immune induced molecule 100.874
CecA2Cecropin A20.874
CecCCecropin C0.842
IM2Immune induced molecule 20.840
CG32185CG32185 gene product from transcript CG32185-RA0.832
imdimmune deficiency0.831
BG4CG12297 gene product from transcript CG12297-RA0.820
Spn28DSerpin 28D0.815
Sp7Serine protease 70.794
CG18067CG18067 gene product from transcript CG18067-RA0.779
PGRP-SB1CG9681 gene product from transcript CG9681-RA0.775
CG16718CG16718 gene product from transcript CG16718-RA0.704
IM18Immune induced molecule 180.695
18w18 wheeler0.646
AGO2Argonaute 20.641
Myd88CG2078 gene product from transcript CG2078-RA0.635
CecA1Cecropin A10.560
CG6361CG6361 gene product from transcript CG6361-RA0.531
ird1immune response deficient 10.509
GNBP3Gram-negative bacteria binding protein 30.501
IM4Immune induced molecule 40.497
pirkpoor Imd response upon knock-in0.443
CG16836CG16836 gene product from transcript CG16836-RA0.424
CG15067CG15067 gene product from transcript CG15067-RA0.364
Mpk2CG5475 gene product from transcript CG5475-RB0.284
DuoxDual oxidase0.274
Spn1Serine protease inhibitor 10.264
Traf4TNF-receptor-associated factor 40.241
Tak1TGF-beta activated kinase 10.236
POSHPlenty of SH3s0.231
CecBCecropin B0.224
modSPmodular serine protease0.210
PGRP-LFPeptidoglycan recognition protein LF0.198
GNBP1Gram-negative bacteria binding protein 10.191
p38bCG7393 gene product from transcript CG7393-RA0.187
CG15917CG15917 gene product from transcript CG15917-RA0.178
Spn88EbSerpin 88Eb0.165
CG33470CG33470 gene product from transcript CG33470-RA0.162
CG4757CG4757 gene product from transcript CG4757-RA0.158
CG7910CG7910 gene product from transcript CG7910-RA0.142
eaterCG6124 gene product from transcript CG6124-RB0.137
CG12766CG12766 gene product from transcript CG12766-RA0.135
PGRP-LEPeptidoglycan recognition protein LE0.113
l(3)mbnlethal (3) malignant blood neoplasm0.112
Mes2CG11100 gene product from transcript CG11100-RB0.107
CG3505CG3505 gene product from transcript CG3505-RA0.106
Atg18Autophagy-specific gene 180.106
spiritSerine Protease Immune Response Integrator0.105
TM9SF4CG7364 gene product from transcript CG7364-RA0.104
RpS28bRibosomal protein S28b0.103
IM3Immune induced molecule 30.098
CG18594CG18594 gene product from transcript CG18594-RA0.091
Idgf2Imaginal disc growth factor 20.090
CG16772CG16772 gene product from transcript CG16772-RA0.088
rev7CG2948 gene product from transcript CG2948-RA0.085
Tsf2Transferrin 20.079
Mekk1CG7717 gene product from transcript CG7717-RB0.071
IM23Immune induced molecule 230.071
PvrPDGF- and VEGF-receptor related0.068
CskC-terminal Src kinase0.062
eIF-5ACG3186 gene product from transcript CG3186-RA0.059
TepIIThiolester containing protein II0.056
PGRP-LBPeptidoglycan recognition protein LB0.054
CG9184CG9184 gene product from transcript CG9184-RB0.054
CG8121CG8121 gene product from transcript CG8121-RA0.051
CG9372CG9372 gene product from transcript CG9372-RA0.051
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Tnftumor necrosis factor1.000
Ikbkginhibitor of kappaB kinase gamma1.000
Casp4caspase 4, apoptosis-related cysteine peptidase0.998
Tnfrsf1atumor necrosis factor receptor superfamily, member 1a0.996
Lyz2lysozyme 20.990
Relbavian reticuloendotheliosis viral (v-rel) oncogene related B0.982
Nfkbianuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha0.947
Map3k14mitogen-activated protein kinase kinase kinase 140.922
Trp53transformation related protein 530.916
Relav-rel reticuloendotheliosis viral oncogene homolog A (avian)0.856
Tlr4toll-like receptor 40.827
PycardPYD and CARD domain containing0.811
Nfkb1nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, p1050.746
Nfkb2nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p1000.648
Gbp5guanylate binding protein 50.592
Gm15315predicted gene 153150.557
Il1binterleukin 1 beta0.548
Defa17defensin, alpha, 170.544
Gm10104predicted gene 101040.532
Defa-rs1defensin, alpha, related sequence 10.512
Ighimmunoglobulin heavy chain complex0.455
Defa20defensin, alpha, 200.452
Foxp3forkhead box P30.393
Ngpneutrophilic granule protein0.385
TcraT-cell receptor alpha chain0.378
S100a9S100 calcium binding protein A9 (calgranulin B)0.369
Gm14850predicted gene 148500.345
Chi3l3chitinase 3-like 30.334
Il18interleukin 180.331
Casp1caspase 10.246
S100a8S100 calcium binding protein A8 (calgranulin A)0.239
Defa21defensin, alpha, 210.239
Cxcl13chemokine (C-X-C motif) ligand 130.231
Defa-rs7defensin, alpha, related sequence 70.229
Prf1perforin 1 (pore forming protein)0.218
Nlrp3NLR family, pyrin domain containing 30.212
Ccl6chemokine (C-C motif) ligand 60.209
Gm15308predicted gene 153080.204
Fpr2formyl peptide receptor 20.202
FasFas (TNF receptor superfamily member 6)0.188
Irf1interferon regulatory factor 10.181
Il1rninterleukin 1 receptor antagonist0.174
Ifnginterferon gamma0.168
Clec4dC-type lectin domain family 4, member d0.166
Card11caspase recruitment domain family, member 110.166
C5ar1complement component 5a receptor 10.165
Mmp8matrix metallopeptidase 80.164
Ccr2chemokine (C-C motif) receptor 20.155
Fbn1fibrillin 10.149
Mapk8ip3mitogen-activated protein kinase 8 interacting protein 30.144
Cd44CD44 antigen0.127
Gm15284predicted gene 152840.127
Il10interleukin 100.120
Slpisecretory leukocyte peptidase inhibitor0.119
Itgb2integrin beta 20.114
Defa24defensin, alpha, 240.101
C3ar1complement component 3a receptor 10.097
Ccl2chemokine (C-C motif) ligand 20.095
Aim2absent in melanoma 20.094
Defa22defensin, alpha, 220.093
Ikzf1IKAROS family zinc finger 10.089
BtkBruton agammaglobulinemia tyrosine kinase0.079
Gm15293predicted gene 152930.078
IghgImmunoglobulin heavy chain (gamma polypeptide)0.076
Mapk14mitogen-activated protein kinase 140.076
Ifitm6interferon induced transmembrane protein 60.076
Rag2recombination activating gene 20.074
Angangiogenin, ribonuclease, RNase A family, 50.074
Il7interleukin 70.074
Tnfsf14tumor necrosis factor (ligand) superfamily, member 140.073
Defa5defensin, alpha, 50.072
Il22interleukin 220.071
Sfpi1SFFV proviral integration 10.070
Ccl8chemokine (C-C motif) ligand 80.066
Map3k8mitogen-activated protein kinase kinase kinase 80.065
Ltbp2latent transforming growth factor beta binding protein 20.063
Bcl3B-cell leukemia/lymphoma 30.062
Runx1runt related transcription factor 10.062
Il6interleukin 60.061
Cd40CD40 antigen0.058
Myd88myeloid differentiation primary response gene 880.056
Traf6TNF receptor-associated factor 60.053
Rps15ribosomal protein S150.053
Reg1regenerating islet-derived 10.053
Reg3gregenerating islet-derived 3 gamma0.052
Csf1colony stimulating factor 1 (macrophage)0.052
Mmp12matrix metallopeptidase 120.052
Clec4eC-type lectin domain family 4, member e0.048
Tnip1TNFAIP3 interacting protein 10.042
Adamdec1ADAM-like, decysin 10.039
Selpselectin, platelet0.038
Defa3defensin, alpha, 30.037
Campcathelicidin antimicrobial peptide0.037
Mmp14matrix metallopeptidase 14 (membrane-inserted)0.036
Fcgr4Fc receptor, IgG, low affinity IV0.036
Ccr1chemokine (C-C motif) receptor 10.036
Col1a1collagen, type I, alpha 10.035
Tbxas1thromboxane A synthase 1, platelet0.035
Loxl1lysyl oxidase-like 10.035
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism