The network for 'trophectodermal cell differentiation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

trophectodermal cell differentiation

The process in which a relatively unspecialized cell acquires the specialized features of a trophectoderm cell.

NameDescriptionProbabilityFunc Analog Organism
GABPAGA binding protein transcription factor, alpha subunit 60kDa0.995
TCF3transcription factor 3 (E2A immunoglobulin enhancer binding factors E12/E47)0.993
POU5F1POU class 5 homeobox 10.990
WWP2WW domain containing E3 ubiquitin protein ligase 20.989
EP300E1A binding protein p3000.925
FOXD3forkhead box D30.904
JUNjun proto-oncogene0.865
SOX2SRY (sex determining region Y)-box 20.850
CTNND1catenin (cadherin-associated protein), delta 10.841
RUNX1runt-related transcription factor 10.836
FOSFBJ murine osteosarcoma viral oncogene homolog0.747
RTF1Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.720
CDC73cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.688
CREBBPCREB binding protein0.673
MYOD1myogenic differentiation 10.669
SETD8SET domain containing (lysine methyltransferase) 80.663
MAFAv-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)0.615
MKL1megakaryoblastic leukemia (translocation) 10.613
ZFP36zinc finger protein 36, C3H type, homolog (mouse)0.588
SMAD4SMAD family member 40.584
POU2F1POU class 2 homeobox 10.564
CNOT2CCR4-NOT transcription complex, subunit 20.551
MYOGmyogenin (myogenic factor 4)0.537
GATA2GATA binding protein 20.490
SP1Sp1 transcription factor0.483
MTA1metastasis associated 10.422
HNF4Ahepatocyte nuclear factor 4, alpha0.411
HIPK2homeodomain interacting protein kinase 20.368
PDX1pancreatic and duodenal homeobox 10.359
JUNDjun D proto-oncogene0.335
NFYAnuclear transcription factor Y, alpha0.321
TCF12transcription factor 120.303
CTNNA1catenin (cadherin-associated protein), alpha 1, 102kDa0.275
ETS2v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)0.265
PAF1Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)0.263
CTNNB1catenin (cadherin-associated protein), beta 1, 88kDa0.255
IER2immediate early response 20.243
CITED2Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 20.236
TFAP2Ctranscription factor AP-2 gamma (activating enhancer binding protein 2 gamma)0.232
LEO1Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)0.226
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.219
RELAv-rel reticuloendotheliosis viral oncogene homolog A (avian)0.199
WDR61WD repeat domain 610.189
EGR1early growth response 10.186
SMAD3SMAD family member 30.178
FOSL1FOS-like antigen 10.171
CNOT8CCR4-NOT transcription complex, subunit 80.163
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.159
HMGA1high mobility group AT-hook 10.144
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)0.142
GATA4GATA binding protein 40.137
HCFC1host cell factor C1 (VP16-accessory protein)0.136
GATA1GATA binding protein 1 (globin transcription factor 1)0.132
TCF4transcription factor 40.128
SREBF2sterol regulatory element binding transcription factor 20.117
SOX1SRY (sex determining region Y)-box 10.111
SF3B4splicing factor 3b, subunit 4, 49kDa0.108
VDRvitamin D (1,25- dihydroxyvitamin D3) receptor0.098
TRIM33tripartite motif containing 330.090
AATFapoptosis antagonizing transcription factor0.083
ATF7IPactivating transcription factor 7 interacting protein0.082
HOXD12homeobox D120.081
NFYCnuclear transcription factor Y, gamma0.079
SMAD1SMAD family member 10.078
PSEN1presenilin 10.073
TAL1T-cell acute lymphocytic leukemia 10.071
CNOT1CCR4-NOT transcription complex, subunit 10.070
ATF3activating transcription factor 30.069
MKL2MKL/myocardin-like 20.069
NCOR2nuclear receptor corepressor 20.068
LHX5LIM homeobox 50.064
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 40.064
HAND2heart and neural crest derivatives expressed 20.064
ESR1estrogen receptor 10.061
SFRP5secreted frizzled-related protein 50.061
TCF7L2transcription factor 7-like 2 (T-cell specific, HMG-box)0.060
SIX6SIX homeobox 60.058
SMAD2SMAD family member 20.056
HNF1AHNF1 homeobox A0.055
HNRNPUL1heterogeneous nuclear ribonucleoprotein U-like 10.054
FGF3fibroblast growth factor 30.053
CBFA2T3core-binding factor, runt domain, alpha subunit 2; translocated to, 30.052
ID1inhibitor of DNA binding 1, dominant negative helix-loop-helix protein0.051
KBTBD7kelch repeat and BTB (POZ) domain containing 70.050
BTBD10BTB (POZ) domain containing 100.049
FOSBFBJ murine osteosarcoma viral oncogene homolog B0.048
HOXB9homeobox B90.048
CUL2cullin 20.047
PHOX2Apaired-like homeobox 2a0.047
CDH3cadherin 3, type 1, P-cadherin (placental)0.046
HAP1huntingtin-associated protein 10.045
DUSP1dual specificity phosphatase 10.045
CCDC86coiled-coil domain containing 860.044
KLF4Kruppel-like factor 4 (gut)0.043
BATF2basic leucine zipper transcription factor, ATF-like 20.043
CUL1cullin 10.043
FOXB1forkhead box B10.042
SP3Sp3 transcription factor0.041
SMAD7SMAD family member 70.040
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Pitx2paired-like homeodomain transcription factor 21.000
Shhsonic hedgehog1.000
Otx2orthodenticle homolog 2 (Drosophila)1.000
Gli3GLI-Kruppel family member GLI31.000
Tcfap2atranscription factor AP-2, alpha0.999
Foxc1forkhead box C10.999
Hand1heart and neural crest derivatives expressed transcript 10.997
Pax2paired box gene 20.996
Hand2heart and neural crest derivatives expressed transcript 20.996
Tbx3T-box 30.995
Bmp4bone morphogenetic protein 40.993
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)0.993
Sox2SRY-box containing gene 20.992
Msx2homeobox, msh-like 20.992
Fgf8fibroblast growth factor 80.991
Pax3paired box gene 30.988
Fgfr2fibroblast growth factor receptor 20.988
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.987
Msx1homeobox, msh-like 10.984
Pou5f1POU domain, class 5, transcription factor 10.980
Pax6paired box gene 60.979
Sall4sal-like 4 (Drosophila)0.979
Bmp7bone morphogenetic protein 70.978
Tbx1T-box 10.975
Eya1eyes absent 1 homolog (Drosophila)0.968
Foxc2forkhead box C20.958
Isl1ISL1 transcription factor, LIM/homeodomain0.940
Hoxa13homeobox A130.933
Hoxd13homeobox D130.930
Pitx1paired-like homeodomain transcription factor 10.918
Dlx5distal-less homeobox 50.914
Alx4aristaless-like homeobox 40.912
Cdx2caudal type homeobox 20.902
Chd7chromodomain helicase DNA binding protein 70.888
Gbx2gastrulation brain homeobox 20.864
Foxg1forkhead box G10.840
Prrx1paired related homeobox 10.823
Hoxa1homeobox A10.806
Lhx1LIM homeobox protein 10.797
Tlx3T-cell leukemia, homeobox 30.786
NanogNanog homeobox0.774
Foxh1forkhead box H10.763
Tbx15T-box 150.757
Gscgoosecoid homeobox0.723
Sox9SRY-box containing gene 90.700
Otx1orthodenticle homolog 1 (Drosophila)0.695
Tcfap2ctranscription factor AP-2, gamma0.681
Lmx1bLIM homeobox transcription factor 1 beta0.661
Fgf15fibroblast growth factor 150.650
Zic3zinc finger protein of the cerebellum 30.646
Ror2receptor tyrosine kinase-like orphan receptor 20.641
Sox3SRY-box containing gene 30.630
Sall1sal-like 1 (Drosophila)0.612
Vangl2vang-like 2 (van gogh, Drosophila)0.611
Dlx1distal-less homeobox 10.598
Hmx3H6 homeobox 30.587
En1engrailed 10.561
Six3sine oculis-related homeobox 3 homolog (Drosophila)0.540
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.534
Alx1ALX homeobox 10.533
UncxUNC homeobox0.523
Emx1empty spiracles homolog 1 (Drosophila)0.519
Sall3sal-like 3 (Drosophila)0.503
Hoxd11homeobox D110.488
Neurog1neurogenin 10.483
Sp1trans-acting transcription factor 10.481
Six4sine oculis-related homeobox 4 homolog (Drosophila)0.474
Zeb1zinc finger E-box binding homeobox 10.472
Igdcc3immunoglobulin superfamily, DCC subclass, member 30.466
Dkk1dickkopf homolog 1 (Xenopus laevis)0.451
Hoxa9homeobox A90.439
Gdf5growth differentiation factor 50.433
Ptpn11protein tyrosine phosphatase, non-receptor type 110.424
Gata6GATA binding protein 60.423
Emx2empty spiracles homolog 2 (Drosophila)0.423
Smosmoothened homolog (Drosophila)0.412
Dlx2distal-less homeobox 20.402
Ascl1achaete-scute complex homolog 1 (Drosophila)0.398
Trp63transformation related protein 630.396
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.371
Sox11SRY-box containing gene 110.369
Yap1yes-associated protein 10.368
Wnt1wingless-related MMTV integration site 10.368
Gata4GATA binding protein 40.363
Lmx1aLIM homeobox transcription factor 1 alpha0.360
Foxa2forkhead box A20.359
Fgfr1fibroblast growth factor receptor 10.347
Hoxb13homeobox B130.334
Runx2runt related transcription factor 20.334
Lef1lymphoid enhancer binding factor 10.332
Atoh1atonal homolog 1 (Drosophila)0.332
Neurog2neurogenin 20.328
Lhx5LIM homeobox protein 50.328
Fgf3fibroblast growth factor 30.319
Ptenphosphatase and tensin homolog0.318
Efna2ephrin A20.313
Foxd3forkhead box D30.313
Pax8paired box gene 80.308
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism