The network for 'positive regulation of gtpase activity' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

positive regulation of gtpase activity

Any process that activates or increases the activity of a GTPase.

NameDescriptionProbabilityFunc Analog Organism
YWHAZtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide1.000
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)1.000
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide1.000
SRCv-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)1.000
MLLT4myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 40.999
ARHGDIARho GDP dissociation inhibitor (GDI) alpha0.998
RHOAras homolog gene family, member A0.992
PAK1p21 protein (Cdc42/Rac)-activated kinase 10.990
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.984
YWHAGtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide0.977
SFNstratifin0.976
RAF1v-raf-1 murine leukemia viral oncogene homolog 10.973
ARRB1arrestin, beta 10.966
S100A8S100 calcium binding protein A80.964
PTK2PTK2 protein tyrosine kinase 20.963
S100A6S100 calcium binding protein A60.960
GRB2growth factor receptor-bound protein 20.960
MDM2Mdm2 p53 binding protein homolog (mouse)0.939
ARFGEF1ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)0.924
S100BS100 calcium binding protein B0.923
PAK2p21 protein (Cdc42/Rac)-activated kinase 20.913
ERBB2IPerbb2 interacting protein0.902
ASAP1ArfGAP with SH3 domain, ankyrin repeat and PH domain 10.895
ITSN1intersectin 1 (SH3 domain protein)0.889
S100A11S100 calcium binding protein A110.888
SH3BP2SH3-domain binding protein 20.880
DNM1dynamin 10.879
IGF1Rinsulin-like growth factor 1 receptor0.877
SH3RF1SH3 domain containing ring finger 10.872
VAV1vav 1 guanine nucleotide exchange factor0.860
ARHGEF11Rho guanine nucleotide exchange factor (GEF) 110.847
LAMTOR2late endosomal/lysosomal adaptor, MAPK and MTOR activator 20.834
TSC2tuberous sclerosis 20.820
GIT1G protein-coupled receptor kinase interacting ArfGAP 10.816
DOCK1dedicator of cytokinesis 10.799
CNKSR2connector enhancer of kinase suppressor of Ras 20.792
BBS10Bardet-Biedl syndrome 100.785
PTPN13protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase)0.776
RGS2regulator of G-protein signaling 2, 24kDa0.774
SNX9sorting nexin 90.771
NCF2neutrophil cytosolic factor 20.761
MYO9Bmyosin IXB0.745
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.742
SYNJ1synaptojanin 10.739
SH3KBP1SH3-domain kinase binding protein 10.735
DNM2dynamin 20.732
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.730
WASLWiskott-Aldrich syndrome-like0.716
S100A9S100 calcium binding protein A90.712
CCR5chemokine (C-C motif) receptor 50.708
PARD6Gpar-6 partitioning defective 6 homolog gamma (C. elegans)0.708
ADRBK1adrenergic, beta, receptor kinase 10.702
GRB7growth factor receptor-bound protein 70.696
EXOSC10exosome component 100.695
SOS1son of sevenless homolog 1 (Drosophila)0.673
TNK2tyrosine kinase, non-receptor, 20.673
RASA1RAS p21 protein activator (GTPase activating protein) 10.660
NCKAP1NCK-associated protein 10.656
SLC9A3R1solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 10.652
HRASv-Ha-ras Harvey rat sarcoma viral oncogene homolog0.650
PLCG1phospholipase C, gamma 10.642
GNB1guanine nucleotide binding protein (G protein), beta polypeptide 10.640
RAC2ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)0.632
S100A1S100 calcium binding protein A10.628
MAGI2membrane associated guanylate kinase, WW and PDZ domain containing 20.620
DSPdesmoplakin0.611
RAB5ARAB5A, member RAS oncogene family0.592
RABGAP1RAB GTPase activating protein 10.590
LAMTOR1late endosomal/lysosomal adaptor, MAPK and MTOR activator 10.585
RND1Rho family GTPase 10.580
ABI1abl-interactor 10.573
SNAP23synaptosomal-associated protein, 23kDa0.564
PSTPIP1proline-serine-threonine phosphatase interacting protein 10.563
ZYXzyxin0.561
CALM1calmodulin 1 (phosphorylase kinase, delta)0.559
CBLBCas-Br-M (murine) ecotropic retroviral transforming sequence b0.557
FMNL1formin-like 10.542
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.537
TSC1tuberous sclerosis 10.536
LMNAlamin A/C0.534
RACGAP1Rac GTPase activating protein 10.531
ZMYND11zinc finger, MYND-type containing 110.529
GAS7growth arrest-specific 70.527
PVRL1poliovirus receptor-related 1 (herpesvirus entry mediator C)0.527
YWHAQtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide0.526
CDKN1Acyclin-dependent kinase inhibitor 1A (p21, Cip1)0.522
MARK3MAP/microtubule affinity-regulating kinase 30.511
HDAC6histone deacetylase 60.507
WASWiskott-Aldrich syndrome (eczema-thrombocytopenia)0.505
BCL2L1BCL2-like 10.502
PVRL2poliovirus receptor-related 2 (herpesvirus entry mediator B)0.495
MPRIPmyosin phosphatase Rho interacting protein0.485
BCRbreakpoint cluster region0.477
CCL4chemokine (C-C motif) ligand 40.474
TRAF5TNF receptor-associated factor 50.459
ZBED1zinc finger, BED-type containing 10.458
SMAD2SMAD family member 20.453
PLECplectin0.445
NCK2NCK adaptor protein 20.433
ROCK1Rho-associated, coiled-coil containing protein kinase 10.430
Loading network...
Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
mpk-1Protein MPK-10.524
goa-1Protein GOA-10.439
CELE_F47G4.4Protein F47G4.40.389
lag-1Protein LAG-10.360
rpm-1Protein RPM-10.267
plc-3Protein PLC-30.259
sem-5Protein SEM-50.243
C11E4.6Protein C11E4.60.218
abl-1Protein ABL-10.208
let-60Protein LET-600.186
rig-6Protein RIG-60.176
unc-53Protein UNC-530.159
sad-1Protein SAD-10.151
CELE_T10D4.6Protein T10D4.60.147
pry-1Protein PRY-10.144
itr-1Protein ITR-10.135
egrh-1Protein EGRH-10.127
zfp-3Protein ZFP-30.124
snf-1Protein SNF-10.117
egl-18Protein EGL-180.113
sup-17Protein SUP-170.107
eor-2Protein EOR-20.107
lin-45Protein LIN-450.106
fhod-1Protein FHOD-10.106
afd-1Protein AFD-10.101
Y54E5A.7Protein Y54E5A.70.101
zoo-1Protein ZOO-10.098
cyld-1Protein CYLD-10.098
mei-1Protein MEI-10.094
unc-71Protein UNC-710.093
C15H9.5Protein C15H9.50.093
flh-2Protein FLH-20.092
rps-2Protein RPS-20.092
morc-1Protein MORC-10.091
pat-3Protein PAT-30.090
rme-4Protein RME-40.088
ptp-4Protein PTP-40.080
stau-1Protein STAU-10.077
chc-1Protein CHC-10.076
T28B11.1Protein T28B11.10.073
egl-8Protein EGL-80.073
atg-2Protein ATG-20.071
tmd-2Protein TMD-20.070
atg-11Protein ATG-110.070
sax-3Protein SAX-30.069
unc-73Protein UNC-730.068
F52G3.1Protein F52G3.10.065
vab-8Protein VAB-80.064
rab-5Protein RAB-50.064
unc-26Protein UNC-260.064
coh-3Protein COH-30.064
tag-343Protein TAG-3430.061
magi-1Protein MAGI-10.061
iglr-1Protein IGLR-10.060
dpy-21Protein DPY-210.060
unc-16Protein UNC-160.060
T23F11.1Protein T23F11.10.058
R90.1Protein R90.10.056
miro-1Protein MIRO-10.056
ptr-5Protein PTR-50.056
cah-6Protein CAH-60.056
ptp-1Protein PTP-10.056
sav-1Protein SAV-10.055
rgr-1Protein RGR-10.054
tmc-2Protein TMC-20.054
cgef-1Protein CGEF-10.054
mel-28Protein MEL-280.054
gap-2Protein GAP-20.053
ash-2Protein ASH-20.051
CELE_W07A8.2Protein W07A8.20.051
pqn-39Protein PQN-390.051
ajm-1Protein AJM-10.050
skn-1Protein SKN-10.050
etr-1Protein ETR-10.050
sym-4Protein SYM-40.049
tbc-12Protein TBC-120.047
Y48C3A.14Protein Y48C3A.140.046
B0001.7Protein B0001.70.046
pfd-6Protein PFD-60.046
par-3Protein PAR-30.045
ykt-6Protein YKT-60.045
K09E4.4Protein K09E4.40.044
F28B3.1Protein F28B3.10.044
pak-1Protein PAK-10.043
unc-79Protein UNC-790.043
mtm-3Protein MTM-30.043
dpy-27Protein DPY-270.043
CELE_C52D10.12Protein C52D10.120.043
frm-7Protein FRM-70.042
C06G1.5Protein C06G1.50.041
rhgf-2Protein RHGF-20.041
ist-1Protein IST-10.039
rpl-3Protein RPL-30.039
par-6Protein PAR-60.039
T23F2.2Protein T23F2.20.039
nep-21Protein NEP-210.039
gly-7Protein GLY-70.038
rgl-1Protein RGL-10.038
sam-10Protein SAM-100.037
larp-5Protein LARP-50.037
Loading network...
Danio rerio
NameDescriptionProbabilityFunc Analog Organism
adrb2aadrenergic receptor, beta 2a0.315
nf1aneurofibromin 1a0.286
rtcd1RNA terminal phosphate cyclase domain 10.268
cnn2calponin 20.262
bidaBH3 interacting domain death agonist0.236
gnaiaguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide a0.203
cebpbCCAAT/enhancer binding protein (C/EBP), beta0.199
bcl2B-cell leukemia/lymphoma 20.198
gnai2lguanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2, like0.191
mcl1bmyeloid cell leukemia sequence 1b0.180
zgc:77517zgc:775170.155
mcm6MCM6 minichromosome maintenance deficient 6, mitotin (S. cerevisiae)0.148
tm9sf2transmembrane 9 superfamily member 20.147
tpm4tropomyosin 40.132
gna12guanine nucleotide binding protein (G protein) alpha 120.126
msnamoesin a0.112
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.109
whsc1Wolf-Hirschhorn syndrome candidate 10.107
yrkYes-related kinase0.101
acsl4aacyl-CoA synthetase long-chain family member 4a0.099
LOC567131calcitonin gene-related peptide type 1 receptor-like0.088
iqgap1IQ motif containing GTPase activating protein 10.083
mcl1amyeloid cell leukemia sequence 1a0.079
ilkintegrin linked kinase0.078
krt8keratin 80.078
tsc22d3TSC22 domain family, member 30.077
nf1bneurofibromin 1b0.076
rtn1areticulon 1a0.072
arpc1aactin related protein 2/3 complex, subunit 1A0.071
si:ch211-232m7.1si:ch211-232m7.10.071
yap1Yes-associated protein 10.068
stmn4stathmin-like 40.068
dmbx1bdiencephalon/mesencephalon homeobox 1b0.067
zgc:112329zgc:1123290.067
gng12aguanine nucleotide binding protein (G protein), gamma 12a0.066
ywhaityrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide0.066
nrasneuroblastoma RAS viral (v-ras) oncogene homolog0.065
ptgs2aprostaglandin-endoperoxide synthase 2a0.065
lifrbleukemia inhibitory factor receptor alpha b0.063
anxa2aannexin A2a0.063
dnmt7DNA (cytosine-5-)-methyltransferase 70.062
icnictacalcin0.062
cebpdCCAAT/enhancer binding protein (C/EBP), delta0.061
zgc:92392zgc:923920.061
ldb1aLIM-domain binding factor 1a0.060
cdc42ep1CDC42 effector protein (Rho GTPase binding) 10.059
junjun proto-oncogene0.059
gnai1guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 10.059
tbeta-abeta thymosin-like protein 20.057
pfn1profilin 10.056
nus1nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)0.056
ppargperoxisome proliferator activated receptor gamma0.055
rrp12ribosomal RNA processing 12 homolog (S. cerevisiae)0.055
unc5bunc-5 homolog B (C. elegans)0.055
zgc:64106zgc:641060.055
b3gnt5aUDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a0.054
bcl2l1bcl2-like 10.054
slc7a3solute carrier family 7 (cationic amino acid transporter, y+ system), member 30.054
pak2ap21 (CDKN1A)-activated kinase 2a0.054
birc2baculoviral IAP repeat-containing 20.053
LOC565839tumor necrosis factor alpha-induced protein 2-like0.053
pdlim1PDZ and LIM domain 1 (elfin)0.053
perpPERP, TP53 apoptosis effector0.050
zbtb4zinc finger and BTB domain containing 40.050
rps6ka3aribosomal protein S6 kinase, polypeptide 3a0.050
dusp4dual specificity phosphatase 40.049
adrb3aadrenergic receptor, beta 3a0.049
scinlbscinderin like b0.049
zgc:153997zgc:1539970.048
rorcaRAR-related orphan receptor C a0.048
mycbp2MYC binding protein 20.048
s100v2S100 calcium binding protein V20.047
optcopticin0.047
pmaip1phorbol-12-myristate-13-acetate-induced protein 10.046
vdrbvitamin D receptor b0.046
rrm2ribonucleotide reductase M2 polypeptide0.045
robo4roundabout homolog 40.045
gltscr1glioma tumor suppressor candidate region gene 10.045
zgc:63587zgc:635870.045
gstalglutathione S-transferase, alpha-like0.045
dzip1DAZ interacting protein 10.044
mapk14amitogen-activated protein kinase 14a0.044
si:dkey-21k24.2si:dkey-21k24.20.044
efna1bephrin A1b0.044
smyd3SET and MYND domain containing 30.044
gna13bguanine nucleotide binding protein (G protein), alpha 13b0.044
zgc:101810zgc:1018100.043
copebcore promoter element binding protein0.043
fbxw11bF-box and WD-40 domain protein 11b0.043
zgc:56466zgc:564660.043
slc4a2asolute carrier family 4, anion exchanger, member 2a0.043
eprsglutamyl-prolyl-tRNA synthetase0.043
fam107bfamily with sequence similarity 107, member B0.043
cacnb1calcium channel, voltage-dependent, beta 1 subunit0.042
baxabcl2-associated X protein, a0.042
phlda2pleckstrin homology-like domain, family A, member 20.042
lingo1aleucine rich repeat and Ig domain containing 1a0.042
ctsbacathepsin B, a0.042
im:7137453im:71374530.042
sgpp1sphingosine-1-phosphate phosphatase 10.042
Loading network...
Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
mbcmyoblast city0.939
cnocanoe0.793
rokRho-kinase0.749
LIMK1LIM-kinase10.730
PknProtein kinase related to protein kinase N0.655
plexBplexin B0.636
PtenCG5671 gene product from transcript CG5671-RB0.623
enaenabled0.616
WnkCG7177 gene product from transcript CG7177-RA0.601
bazbazooka0.511
SbfSET domain binding factor0.470
pod1CG4532 gene product from transcript CG4532-RF0.468
pblpebble0.440
Pi3K92ECG4141 gene product from transcript CG4141-RB0.365
RhoBTBCG5701 gene product from transcript CG5701-RA0.361
AbiAbelson interacting protein0.361
pucpuckered0.356
NNotch0.354
tutlturtle0.333
CalpBCalpain-B0.322
Myo31DFMyosin 31DF0.303
CG9426CG9426 gene product from transcript CG9426-RA0.293
RhoGAP68FCG6811 gene product from transcript CG6811-RA0.291
lgslegless0.286
mysmyospheroid0.282
Smg1CG32743 gene product from transcript CG32743-RA0.282
HphHIF prolyl hydroxylase0.276
Vps35Vacuolar protein sorting 350.274
NaCP60ENa channel protein 60E0.239
diadiaphanous0.231
Vps45Vacuolar protein sorting 450.226
rapsrapsynoid0.224
CG7158CG7158 gene product from transcript CG7158-RA0.218
simasimilar0.212
CycACyclin A0.208
cenG1Acentaurin gamma 1A0.207
neurneuralized0.206
Prp31CG6876 gene product from transcript CG6876-RA0.201
synjsynaptojanin0.192
RhoGEF2CG9635 gene product from transcript CG9635-RF0.190
CG32772CG32772 gene product from transcript CG32772-RC0.174
CG8334CG8334 gene product from transcript CG8334-RA0.170
smosmoothened0.167
l(2)k16918lethal (2) k169180.164
staistathmin0.161
stgstring0.159
Stat92ESignal-transducer and activator of transcription protein at 92E0.158
CG6509CG6509 gene product from transcript CG6509-RB0.150
mbtmushroom bodies tiny0.146
yataCG1973 gene product from transcript CG1973-RA0.145
Zyx102EFCG32018 gene product from transcript CG32018-RA0.143
neuroliginCG13772 gene product from transcript CG13772-RA0.142
SosSon of sevenless0.139
nwknervous wreck0.134
jarjaguar0.127
CG17233CG17233 gene product from transcript CG17233-RA0.125
Mkp3Mitogen-activated protein kinase phosphatase 30.125
Rho1CG8416 gene product from transcript CG8416-RB0.121
NELF-ACG5874 gene product from transcript CG5874-RA0.119
sizschizo0.117
MtlMig-2-like0.115
ctaconcertina0.115
kenken and barbie0.114
CG2991CG2991 gene product from transcript CG2991-RA0.113
Tre1trapped in endoderm-10.108
ptcpatched0.108
Dap160Dynamin associated protein 1600.106
JraJun-related antigen0.100
DAAMDishevelled Associated Activator of Morphogenesis0.099
CG8155CG8155 gene product from transcript CG8155-RA0.099
flwflapwing0.098
klarklarsicht0.097
kuzkuzbanian0.096
Cdk5alphaCdk5 activator-like protein0.094
l(2)k05819lethal (2) k058190.093
HemHEM-protein0.089
CG4552CG4552 gene product from transcript CG4552-RA0.088
unc-104CG8566 gene product from transcript CG8566-RB0.086
sglsugarless0.085
alpha-Man-IIalpha Mannosidase II0.084
ttktramtrack0.084
drprdraper0.081
rheaCG6831 gene product from transcript CG6831-RA0.081
rlrolled0.080
Traf4TNF-receptor-associated factor 40.079
HiraCG12153 gene product from transcript CG12153-RA0.079
Pk61CProtein kinase 61C0.078
RhebCG1081 gene product from transcript CG1081-RA0.077
UBL3CG9038 gene product from transcript CG9038-RC0.075
Unc-76CG3981 gene product from transcript CG3981-RB0.075
GrafCG8948 gene product from transcript CG8948-RB0.073
tmodtropomodulin0.073
dockdreadlocks0.071
CG9063CG9063 gene product from transcript CG9063-RA0.071
slprslipper0.070
synaptogyrinCG10808 gene product from transcript CG10808-RA0.070
CG15118CG15118 gene product from transcript CG15118-RC0.070
p120ctnAdherens junction protein p1200.069
Act5CActin 5C0.069
Hnf4Hepatocyte nuclear factor 40.068
Loading network...
Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Sema6asema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A0.973
Dlg4discs, large homolog 4 (Drosophila)0.961
Grin1glutamate receptor, ionotropic, NMDA1 (zeta 1)0.949
Arrb2arrestin, beta 20.946
Grb2growth factor receptor bound protein 20.930
Leprleptin receptor0.922
Pafah1b1platelet-activating factor acetylhydrolase, isoform 1b, subunit 10.904
BrafBraf transforming gene0.899
Itsn1intersectin 1 (SH3 domain protein 1A)0.842
Akt1thymoma viral proto-oncogene 10.837
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.818
Drd2dopamine receptor D20.809
Arhgef11Rho guanine nucleotide exchange factor (GEF) 110.804
Ptk2bPTK2 protein tyrosine kinase 2 beta0.779
Prkccprotein kinase C, gamma0.777
Ccl2chemokine (C-C motif) ligand 20.758
Epha4Eph receptor A40.695
Nf1neurofibromatosis 10.690
Chrm1cholinergic receptor, muscarinic 1, CNS0.684
Selplgselectin, platelet (p-selectin) ligand0.676
Hmha1histocompatibility (minor) HA-10.651
Cd44CD44 antigen0.647
Klklotho0.642
CblCasitas B-lineage lymphoma0.635
BaxBCL2-associated X protein0.632
Sh3bgrlSH3-binding domain glutamic acid-rich protein like0.632
Ilkintegrin linked kinase0.614
Tsc1tuberous sclerosis 10.590
Ephb2Eph receptor B20.589
Pip4k2aphosphatidylinositol-5-phosphate 4-kinase, type II, alpha0.585
Plxna3plexin A30.574
Sox10SRY-box containing gene 100.568
Plxna1plexin A10.560
Stag2stromal antigen 20.557
Ntrk2neurotrophic tyrosine kinase, receptor, type 20.555
Map3k14mitogen-activated protein kinase kinase kinase 140.547
Rac1RAS-related C3 botulinum substrate 10.544
Pxnpaxillin0.533
Asap1ArfGAP with SH# domain, ankyrin repeat and PH domain10.528
Arhgap30Rho GTPase activating protein 300.516
Bcl2B-cell leukemia/lymphoma 20.513
Lrrk2leucine-rich repeat kinase 20.483
Wipf1WAS/WASL interacting protein family, member 10.483
Erbb2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.483
Epb4.1l2erythrocyte protein band 4.1-like 20.479
Vav3vav 3 oncogene0.474
Ccr2chemokine (C-C motif) receptor 20.460
Cd37CD37 antigen0.460
Gpsm3G-protein signalling modulator 3 (AGS3-like, C. elegans)0.458
Efnb2ephrin B20.449
Mark4MAP/microtubule affinity-regulating kinase 40.449
Adrbk1adrenergic receptor kinase, beta 10.449
Grin2bglutamate receptor, ionotropic, NMDA2B (epsilon 2)0.441
Ppargperoxisome proliferator activated receptor gamma0.414
Rasgrp1RAS guanyl releasing protein 10.405
Tmod3tropomodulin 30.404
Vav1vav 1 oncogene0.398
Nr3c1nuclear receptor subfamily 3, group C, member 10.393
Srgap2SLIT-ROBO Rho GTPase activating protein 20.386
Bcrbreakpoint cluster region0.378
Pde1bphosphodiesterase 1B, Ca2+-calmodulin dependent0.375
Vdrvitamin D receptor0.371
Mkl1MKL (megakaryoblastic leukemia)/myocardin-like 10.363
Sh3bp1SH3-domain binding protein 10.359
Cdk14cyclin-dependent kinase 140.355
Nrbp2nuclear receptor binding protein 20.354
Gnb2guanine nucleotide binding protein (G protein), beta 20.353
Ctnnb1catenin (cadherin associated protein), beta 10.353
Stxbp3asyntaxin binding protein 3A0.347
Sstr4somatostatin receptor 40.346
Eps15epidermal growth factor receptor pathway substrate 150.342
Pik3cdphosphatidylinositol 3-kinase catalytic delta polypeptide0.340
Cacna1bcalcium channel, voltage-dependent, N type, alpha 1B subunit0.338
Itga3integrin alpha 30.337
Camk2acalcium/calmodulin-dependent protein kinase II alpha0.333
Adrb1adrenergic receptor, beta 10.328
Cdc42cell division cycle 42 homolog (S. cerevisiae)0.325
Wnt7awingless-related MMTV integration site 7A0.322
Gfra2glial cell line derived neurotrophic factor family receptor alpha 20.322
Ntf3neurotrophin 30.314
Pnpla2patatin-like phospholipase domain containing 20.312
Nf2neurofibromatosis 20.305
Parvaparvin, alpha0.301
Phlpp1PH domain and leucine rich repeat protein phosphatase 10.295
Plcg1phospholipase C, gamma 10.293
Grid1glutamate receptor, ionotropic, delta 10.292
Magi1membrane associated guanylate kinase, WW and PDZ domain containing 10.291
Fzd1frizzled homolog 1 (Drosophila)0.289
Laptm5lysosomal-associated protein transmembrane 50.285
Rasgrp2RAS, guanyl releasing protein 20.281
Apcadenomatosis polyposis coli0.281
Grin2dglutamate receptor, ionotropic, NMDA2D (epsilon 4)0.274
Ptk2PTK2 protein tyrosine kinase 20.273
Npas2neuronal PAS domain protein 20.271
Shc1src homology 2 domain-containing transforming protein C10.268
Prkcdprotein kinase C, delta0.265
Vav2vav 2 oncogene0.265
Kalrnkalirin, RhoGEF kinase0.261
B3gat1beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)0.251
SrcRous sarcoma oncogene0.250
Loading network...
Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Pip4k2bphosphatidylinositol-5-phosphate 4-kinase, type II, beta0.191
Kcnab2potassium voltage-gated channel, shaker-related subfamily, beta member 20.159
Dag1dystroglycan 1 (dystrophin-associated glycoprotein 1)0.132
Flt1FMS-related tyrosine kinase 10.101
Inpp5dinositol polyphosphate-5-phosphatase D0.087
Pctk2PCTAIRE protein kinase 20.086
Arf4ADP-ribosylation factor 40.083
Cyth1cytohesin 10.079
Sirpasignal-regulatory protein alpha0.075
Epas1endothelial PAS domain protein 10.072
Itpr1inositol 1,4,5-triphosphate receptor, type 10.072
Lcp2lymphocyte cytosolic protein 20.071
Mapk9mitogen-activated protein kinase 90.070
Dlg3discs, large homolog 3 (Drosophila)0.069
Bin2bridging integrator 20.068
Zfp238zinc finger protein 2380.068
Hand2heart and neural crest derivatives expressed 20.067
Kitv-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog0.066
Cfpcomplement factor properdin0.065
Adrbk1adrenergic, beta, receptor kinase 10.064
Camk4calcium/calmodulin-dependent protein kinase IV0.063
Gng7guanine nucleotide binding protein (G protein), gamma 70.060
Copb1coatomer protein complex, subunit beta 10.059
RfngRFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase0.058
Gucy1b3guanylate cyclase 1, soluble, beta 30.056
Prkchprotein kinase C, eta0.054
Homer1homer homolog 1 (Drosophila)0.053
Shank2SH3 and multiple ankyrin repeat domains 20.052
Dapk3death-associated protein kinase 30.049
Sdc3syndecan 30.048
Prkcbprotein kinase C, beta0.048
Clcn7chloride channel 70.047
Pja2praja 2, RING-H2 motif containing0.046
Cd37CD37 molecule0.046
Tgfbr2transforming growth factor, beta receptor II0.046
Cdc34cell division cycle 34 homolog (S. cerevisiae)0.045
Copb2coatomer protein complex, subunit beta 2 (beta prime)0.044
Plekha6pleckstrin homology domain containing, family A member 60.043
Gabra4gamma-aminobutyric acid (GABA) A receptor, alpha 40.043
Dnm2dynamin 20.041
Mmp17matrix metallopeptidase 170.041
Cdc42bpbCDC42 binding protein kinase beta (DMPK-like)0.040
Pi4kaphosphatidylinositol 4-kinase, catalytic, alpha0.040
Arhgef7Rho guanine nucleotide exchange factor (GEF7)0.040
Kif16bkinesin family member 16B0.040
Ptafrplatelet-activating factor receptor0.040
Sox17SRY (sex determining region Y)-box 170.040
Arhgap4Rho GTPase activating protein 40.040
Wdr7WD repeat domain 70.038
Tgfb1transforming growth factor, beta 10.038
Ptprsprotein tyrosine phosphatase, receptor type, S0.038
Mcpt4mast cell protease 40.038
Stk39serine/threonine kinase 39, STE20/SPS1 homolog (yeast)0.038
Rassf5Ras association (RalGDS/AF-6) domain family member 50.038
TekTEK tyrosine kinase, endothelial0.037
Cugbp2CUG triplet repeat, RNA binding protein 20.036
Gria2glutamate receptor, ionotropic, AMPA 20.035
Rararetinoic acid receptor, alpha0.035
Nckap1NCK-associated protein 10.035
Git1G protein-coupled receptor kinase interacting ArfGAP 10.035
Adcy5adenylate cyclase 50.035
Cyyr1cysteine/tyrosine-rich 10.034
Gucy1a3guanylate cyclase 1, soluble, alpha 30.034
Vps52vacuolar protein sorting 52 homolog (S. cerevisiae)0.034
Abcf3ATP-binding cassette, subfamily F (GCN20), member 30.034
Macf1microtubule-actin crosslinking factor 10.033
Sh3kbp1SH3-domain kinase binding protein 10.033
Rgs4regulator of G-protein signaling 40.032
Pik3cdphosphoinositide-3-kinase, catalytic, delta polypeptide0.032
GraspGRP1 (general receptor for phosphoinositides 1)-associated scaffold protein0.032
Cdc37cell division cycle 37 homolog (S. cerevisiae)0.031
Mertkc-mer proto-oncogene tyrosine kinase0.031
Add3adducin 3 (gamma)0.031
Unc13bunc-13 homolog B (C. elegans)0.031
Elf1E74-like factor 10.030
Med23mediator complex subunit 230.030
NsfN-ethylmaleimide-sensitive factor0.030
Adora2aadenosine A2a receptor0.030
Hk1hexokinase 10.030
Brafv-raf murine sarcoma viral oncogene homolog B10.030
Lynv-yes-1 Yamaguchi sarcoma viral related oncogene homolog0.030
Mospd2motile sperm domain containing 20.030
Arpc2actin related protein 2/3 complex, subunit 20.030
Pde2aphosphodiesterase 2A, cGMP-stimulated0.030
Plcg1phospholipase C, gamma 10.029
RGD621098similar to RIKEN cDNA D230025D16Rik0.029
Smg5Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)0.028
Extl3exostoses (multiple)-like 30.028
Glra1glycine receptor, alpha 10.028
Stx2syntaxin 20.028
Pak1p21 protein (Cdc42/Rac)-activated kinase 10.028
Rab3il1RAB3A interacting protein (rabin3)-like 10.028
Gpr116G protein-coupled receptor 1160.028
Pld2phospholipase D20.028
Scn8asodium channel, voltage gated, type VIII, alpha subunit0.027
Coro1acoronin, actin binding protein 1A0.027
Mxd1max dimerization protein 10.027
Ncr1natural cytotoxicity triggering receptor 10.027
Ap2a1adaptor-related protein complex 2, alpha 1 subunit0.027
Pik3r3phosphoinositide-3-kinase, regulatory subunit 3 (gamma)0.027
Loading network...
Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism
GYL1Gyl1p0.439
GCD6Gcd6p0.402
SUI3Sui3p0.298
STE11Ste11p0.294
IRA1Ira1p0.263
STE5Ste5p0.260
CDC24Cdc24p0.246
RHO1Rho1p0.246
SPA2Spa2p0.211
BEM3Bem3p0.142
MKK1Mkk1p0.122
FYV8Fyv8p0.121
BEM2Bem2p0.109
FAR1Far1p0.102
MDS3Mds3p0.099
MNN9Mnn9p0.082
FMS1Fms1p0.078
GIC2Gic2p0.072
ROM2Rom2p0.068
CHC1Chc1p0.067
HRP1Hrp1p0.063
SLT2Slt2p0.060
CHS1Chs1p0.060
GCD7Gcd7p0.057
MSG5Msg5p0.057
PKC1Pkc1p0.057
ENT1Ent1p0.057
SAC7Sac7p0.056
GCD11Gcd11p0.056
VPS15Vps15p0.056
INP53Inp53p0.055
FUS2Fus2p0.053
SUI2Sui2p0.053
PRS2Prs2p0.051
YPT53Ypt53p0.050
CDC25Cdc25p0.050
VPS9Vps9p0.045
HSV2Hsv2p0.044
KEL1Kel1p0.043
SEC13Sec13p0.043
CCT4Cct4p0.043
YML002Whypothetical protein0.043
CYK3Cyk3p0.043
YIP3Yip3p0.043
PEP5Pep5p0.042
PTP2Ptp2p0.042
CRG1Crg1p0.039
STE4Ste4p0.039
SRP54Srp54p0.038
SOG2Sog2p0.038
SEC16Sec16p0.038
YNL108Chypothetical protein0.038
CDC50Cdc50p0.037
SES1Ses1p0.036
CMK2Cmk2p0.036
YDR186Chypothetical protein0.035
YRB1Yrb1p0.035
AVO1Avo1p0.035
SKT5Skt5p0.034
BST1Bst1p0.034
PDE2Pde2p0.033
SPR6Spr6p0.033
CUE5Cue5p0.032
MOB2Mob2p0.032
YLR264C-Ahypothetical protein0.032
KES1Kes1p0.031
FUS1Fus1p0.031
MEX67Mex67p0.031
SIA1Sia1p0.031
SSK2Ssk2p0.030
CIK1Cik1p0.030
AKL1Akl1p0.029
SVF1Svf1p0.029
PEA2Pea2p0.029
INO2Ino2p0.029
ACK1Ack1p0.029
GLO3Glo3p0.029
URA4Ura4p0.028
GCD1Gcd1p0.028
SKI8Ski8p0.028
YGR126Whypothetical protein0.028
GPB2Gpb2p0.028
SRD1Srd1p0.027
RIM21Rim21p0.027
YFR016Chypothetical protein0.027
NYV1Nyv1p0.027
TRR1Trr1p0.027
STE20Ste20p0.026
URA3Ura3p0.026
BFR1Bfr1p0.026
BCP1Bcp1p0.026
ATG20Atg20p0.026
RPN14Rpn14p0.026
LEU2Leu2p0.026
ITR2Itr2p0.026
KIC1Kic1p0.026
FAA2Faa2p0.026
NUP49Nup49p0.025
MID1Mid1p0.025
KTR4Ktr4p0.025