The network for 'regulation of acrosome reaction' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of acrosome reaction

Any process that modulates the frequency, rate or extent of the acrosome reaction.

NameDescriptionProbabilityFunc Analog Organism
UGT2B7UDP glucuronosyltransferase 2 family, polypeptide B70.907
MAPK15mitogen-activated protein kinase 150.897
HTR2C5-hydroxytryptamine (serotonin) receptor 2C0.697
OPRK1opioid receptor, kappa 10.655
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 50.594
GABRA4gamma-aminobutyric acid (GABA) A receptor, alpha 40.495
SLC1A6solute carrier family 1 (high affinity aspartate/glutamate transporter), member 60.466
SV2Csynaptic vesicle glycoprotein 2C0.459
CDH8cadherin 8, type 20.454
GRM1glutamate receptor, metabotropic 10.446
GABRA3gamma-aminobutyric acid (GABA) A receptor, alpha 30.441
GRIA1glutamate receptor, ionotropic, AMPA 10.435
HTR2A5-hydroxytryptamine (serotonin) receptor 2A0.428
SLC17A6solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 60.412
PRKCGprotein kinase C, gamma0.392
CACNG3calcium channel, voltage-dependent, gamma subunit 30.385
ACTL6Bactin-like 6B0.378
NTRK3neurotrophic tyrosine kinase, receptor, type 30.374
GLRA1glycine receptor, alpha 10.329
SYT13synaptotagmin XIII0.323
GRIK1glutamate receptor, ionotropic, kainate 10.323
SYN2synapsin II0.322
GLRA2glycine receptor, alpha 20.306
SLC24A2solute carrier family 24 (sodium/potassium/calcium exchanger), member 20.305
CRHR1corticotropin releasing hormone receptor 10.287
ACCN1amiloride-sensitive cation channel 1, neuronal0.286
GPC5glypican 50.280
GABRQgamma-aminobutyric acid (GABA) receptor, theta0.273
ADCY1adenylate cyclase 1 (brain)0.273
KCNJ3potassium inwardly-rectifying channel, subfamily J, member 30.268
GABRG2gamma-aminobutyric acid (GABA) A receptor, gamma 20.250
SLITRK3SLIT and NTRK-like family, member 30.249
DAB1disabled homolog 1 (Drosophila)0.244
GABRB1gamma-aminobutyric acid (GABA) A receptor, beta 10.240
NPYneuropeptide Y0.238
RIT2Ras-like without CAAX 20.237
GABRA1gamma-aminobutyric acid (GABA) A receptor, alpha 10.230
HRH3histamine receptor H30.227
SLC8A2solute carrier family 8 (sodium/calcium exchanger), member 20.196
KCNA1potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)0.196
ATP2B3ATPase, Ca++ transporting, plasma membrane 30.193
RIMS2regulating synaptic membrane exocytosis 20.191
SNTG1syntrophin, gamma 10.189
RGS7regulator of G-protein signaling 70.188
SLC12A5solute carrier family 12 (potassium/chloride transporter), member 50.187
SLC1A2solute carrier family 1 (glial high affinity glutamate transporter), member 20.185
KCNQ3potassium voltage-gated channel, KQT-like subfamily, member 30.181
NRXN1neurexin 10.180
CDH10cadherin 10, type 2 (T2-cadherin)0.180
HTR1E5-hydroxytryptamine (serotonin) receptor 1E0.179
DCCdeleted in colorectal carcinoma0.178
NELL1NEL-like 1 (chicken)0.176
NEUROD2neurogenic differentiation 20.176
GRM3glutamate receptor, metabotropic 30.169
CACNG5calcium channel, voltage-dependent, gamma subunit 50.165
CAMKVCaM kinase-like vesicle-associated0.154
FSTL4follistatin-like 40.150
WSCD2WSC domain containing 20.149
GABRR1gamma-aminobutyric acid (GABA) receptor, rho 10.148
GRIA2glutamate receptor, ionotropic, AMPA 20.147
DGKIdiacylglycerol kinase, iota0.147
MYO16myosin XVI0.147
PEX5Lperoxisomal biogenesis factor 5-like0.144
RALYLRALY RNA binding protein-like0.143
OPN1SWopsin 1 (cone pigments), short-wave-sensitive0.139
SCNN1Gsodium channel, nonvoltage-gated 1, gamma0.138
GRM7glutamate receptor, metabotropic 70.137
GRIA3glutamate receptor, ionotrophic, AMPA 30.136
GABRB2gamma-aminobutyric acid (GABA) A receptor, beta 20.135
SSTR2somatostatin receptor 20.132
GRM5glutamate receptor, metabotropic 50.130
CACNB4calcium channel, voltage-dependent, beta 4 subunit0.130
DRD5dopamine receptor D50.129
FGF12fibroblast growth factor 120.129
SLC30A3solute carrier family 30 (zinc transporter), member 30.126
KCNQ2potassium voltage-gated channel, KQT-like subfamily, member 20.126
CA10carbonic anhydrase X0.126
CBLN1cerebellin 1 precursor0.126
STXBP5Lsyntaxin binding protein 5-like0.125
SLC4A3solute carrier family 4, anion exchanger, member 30.125
NHLH2nescient helix loop helix 20.124
MTMR7myotubularin related protein 70.124
TAC1tachykinin, precursor 10.124
GABRG3gamma-aminobutyric acid (GABA) A receptor, gamma 30.123
PAX2paired box 20.122
GLRA3glycine receptor, alpha 30.121
SCN2Asodium channel, voltage-gated, type II, alpha subunit0.118
CNKSR2connector enhancer of kinase suppressor of Ras 20.118
JPH3junctophilin 30.114
SLC17A7solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 70.114
CCKBRcholecystokinin B receptor0.114
RIMS1regulating synaptic membrane exocytosis 10.113
GABRA2gamma-aminobutyric acid (GABA) A receptor, alpha 20.113
KCND2potassium voltage-gated channel, Shal-related subfamily, member 20.108
FAM5Bfamily with sequence similarity 5, member B0.107
GNG4guanine nucleotide binding protein (G protein), gamma 40.105
ADAM18ADAM metallopeptidase domain 180.102
MGAT4Cmannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)0.100
AP3B2adaptor-related protein complex 3, beta 2 subunit0.099
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Rpl18ribosomal protein L180.035
Rpl7ribosomal protein L70.017
Rpl13aribosomal protein L13A0.014
Ywhaetyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide0.013
Olfr70olfactory receptor 700.011
Eif3deukaryotic translation initiation factor 3, subunit D0.010
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Gucy1b3guanylate cyclase 1, soluble, beta 30.021
Hlfhepatic leukemia factor0.019
Smr3asubmaxillary gland androgen regulated protein 3A0.013
Nr3c2nuclear receptor subfamily 3, group C, member 20.011
Apobapolipoprotein B0.010
Spink3serine peptidase inhibitor, Kazal type 30.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism