The network for 'regulation of cardiac muscle cell proliferation' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

regulation of cardiac muscle cell proliferation

Any process that modulates the frequency, rate or extent of cardiac muscle cell proliferation.

NameDescriptionProbabilityFunc Analog Organism
FGFR2fibroblast growth factor receptor 21.000
FGF1fibroblast growth factor 1 (acidic)1.000
CDK2cyclin-dependent kinase 20.999
HDAC1histone deacetylase 10.992
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)0.987
ERBB3v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)0.984
FGF10fibroblast growth factor 100.974
KRT5keratin 50.863
TGFB3transforming growth factor, beta 30.817
MAML1mastermind-like 1 (Drosophila)0.785
RBPJrecombination signal binding protein for immunoglobulin kappa J region0.761
HDAC4histone deacetylase 40.751
JAG1jagged 10.714
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.701
WWOXWW domain containing oxidoreductase0.697
FGFR1fibroblast growth factor receptor 10.683
FRS2fibroblast growth factor receptor substrate 20.678
TGFB1transforming growth factor, beta 10.614
SATB2SATB homeobox 20.590
TTRtransthyretin0.581
PLCG1phospholipase C, gamma 10.571
ANKS1Bankyrin repeat and sterile alpha motif domain containing 1B0.566
EGFRepidermal growth factor receptor0.535
SHC1SHC (Src homology 2 domain containing) transforming protein 10.514
NOTCH1notch 10.503
CCNE1cyclin E10.490
STK3serine/threonine kinase 30.458
CRKv-crk sarcoma virus CT10 oncogene homolog (avian)0.452
STK4serine/threonine kinase 40.445
FGF7fibroblast growth factor 70.441
CCNB1cyclin B10.429
CCNA2cyclin A20.417
EP300E1A binding protein p3000.392
CABLES1Cdk5 and Abl enzyme substrate 10.389
ATXN1Lataxin 1-like0.304
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.263
HDAC9histone deacetylase 90.259
YAP1Yes-associated protein 10.258
NOTCH3notch 30.251
ESR1estrogen receptor 10.248
CDKN2Acyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)0.233
CCNB2cyclin B20.231
MDM2Mdm2 p53 binding protein homolog (mouse)0.210
UBE2Iubiquitin-conjugating enzyme E2I (UBC9 homolog, yeast)0.204
TROtrophinin0.199
FGF2fibroblast growth factor 2 (basic)0.195
KLF13Kruppel-like factor 130.193
LATS2LATS, large tumor suppressor, homolog 2 (Drosophila)0.186
RB1retinoblastoma 10.172
SKP2S-phase kinase-associated protein 2 (p45)0.169
FGFR3fibroblast growth factor receptor 30.168
PIK3R2phosphoinositide-3-kinase, regulatory subunit 2 (beta)0.166
SPENspen homolog, transcriptional regulator (Drosophila)0.163
BMP2bone morphogenetic protein 20.162
RASSF1Ras association (RalGDS/AF-6) domain family member 10.161
ENGendoglin0.160
NCOR2nuclear receptor corepressor 20.152
FSTL1follistatin-like 10.147
TP53BP2tumor protein p53 binding protein, 20.144
TBX5T-box 50.140
CKS2CDC28 protein kinase regulatory subunit 20.136
DLG2discs, large homolog 2 (Drosophila)0.121
MEF2Amyocyte enhancer factor 2A0.113
TNS4tensin 40.110
SEC16ASEC16 homolog A (S. cerevisiae)0.110
NRP1neuropilin 10.099
ITCHitchy E3 ubiquitin protein ligase homolog (mouse)0.095
PPP1R13Bprotein phosphatase 1, regulatory (inhibitor) subunit 13B0.094
BMP7bone morphogenetic protein 70.088
KRT6Ckeratin 6C0.085
GATAD2BGATA zinc finger domain containing 2B0.085
TP73tumor protein p730.079
SGK3serum/glucocorticoid regulated kinase family, member 30.074
GATA4GATA binding protein 40.073
RELv-rel reticuloendotheliosis viral oncogene homolog (avian)0.073
CKS1BCDC28 protein kinase regulatory subunit 1B0.073
NOSTRINnitric oxide synthase trafficker0.070
AMOTL1angiomotin like 10.070
TBX1T-box 10.068
GATA5GATA binding protein 50.068
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.066
ABL2v-abl Abelson murine leukemia viral oncogene homolog 20.064
EPAS1endothelial PAS domain protein 10.063
DLG3discs, large homolog 3 (Drosophila)0.063
TFAP2Atranscription factor AP-2 alpha (activating enhancer binding protein 2 alpha)0.062
TEAD1TEA domain family member 1 (SV40 transcriptional enhancer factor)0.061
FGF8fibroblast growth factor 8 (androgen-induced)0.058
PTPN14protein tyrosine phosphatase, non-receptor type 140.057
SPTBN1spectrin, beta, non-erythrocytic 10.057
MOBKL1AMOB1, Mps One Binder kinase activator-like 1A (yeast)0.055
TGFBR1transforming growth factor, beta receptor 10.055
CDC20cell division cycle 20 homolog (S. cerevisiae)0.055
SNW1SNW domain containing 10.055
S1PR5sphingosine-1-phosphate receptor 50.055
APPamyloid beta (A4) precursor protein0.053
BACH2BTB and CNC homology 1, basic leucine zipper transcription factor 20.053
NKX2-5NK2 transcription factor related, locus 5 (Drosophila)0.052
SNTB2syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)0.052
CIR1corepressor interacting with RBPJ, 10.051
MOBKL1BMOB1, Mps One Binder kinase activator-like 1B (yeast)0.051
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Nkx2-5NK2 transcription factor related, locus 5 (Drosophila)1.000
Shhsonic hedgehog1.000
Fgfr2fibroblast growth factor receptor 21.000
Tbx3T-box 31.000
Gli2GLI-Kruppel family member GLI21.000
Hand2heart and neural crest derivatives expressed transcript 20.999
Pax2paired box gene 20.999
Fgf8fibroblast growth factor 80.994
Gata4GATA binding protein 40.992
Fgf10fibroblast growth factor 100.987
Retret proto-oncogene0.987
Pax3paired box gene 30.985
Gli3GLI-Kruppel family member GLI30.980
Notch1Notch gene homolog 1 (Drosophila)0.977
Foxc1forkhead box C10.971
Hand1heart and neural crest derivatives expressed transcript 10.970
Pitx2paired-like homeodomain transcription factor 20.970
Hoxa13homeobox A130.968
Bmp4bone morphogenetic protein 40.967
Trp63transformation related protein 630.966
Sox9SRY-box containing gene 90.965
Tbx5T-box 50.954
Hoxd13homeobox D130.938
Zfpm2zinc finger protein, multitype 20.930
Itgb1integrin beta 1 (fibronectin receptor beta)0.925
Foxc2forkhead box C20.906
Hoxa1homeobox A10.896
Ptpn11protein tyrosine phosphatase, non-receptor type 110.881
Ptenphosphatase and tensin homolog0.876
Apcadenomatosis polyposis coli0.873
Tbx15T-box 150.862
Jag1jagged 10.861
Fgfr3fibroblast growth factor receptor 30.852
Lmx1aLIM homeobox transcription factor 1 alpha0.839
Ntf3neurotrophin 30.833
Fgfr1fibroblast growth factor receptor 10.825
Ror2receptor tyrosine kinase-like orphan receptor 20.815
Gata6GATA binding protein 60.814
Krasv-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog0.801
Myl2myosin, light polypeptide 2, regulatory, cardiac, slow0.799
Gli1GLI-Kruppel family member GLI10.773
Meox2mesenchyme homeobox 20.764
Shesrc homology 2 domain-containing transforming protein E0.763
Tbx1T-box 10.759
Pitx1paired-like homeodomain transcription factor 10.745
Efnb2ephrin B20.733
Cdx2caudal type homeobox 20.705
Rxraretinoid X receptor alpha0.683
Fgf15fibroblast growth factor 150.676
Otx2orthodenticle homolog 2 (Drosophila)0.666
Trp53transformation related protein 530.652
Tbx2T-box 20.648
Dkk1dickkopf homolog 1 (Xenopus laevis)0.633
Nognoggin0.617
Nodalnodal0.580
Dll4delta-like 4 (Drosophila)0.566
Sox2SRY-box containing gene 20.564
Foxf1aforkhead box F1a0.557
Hoxa11homeobox A110.553
Hoxd11homeobox D110.550
Btbd17BTB (POZ) domain containing 170.546
Fgf18fibroblast growth factor 180.532
Six1sine oculis-related homeobox 1 homolog (Drosophila)0.522
Pthlhparathyroid hormone-like peptide0.511
Pou5f1POU domain, class 5, transcription factor 10.500
Smad6MAD homolog 6 (Drosophila)0.490
Nos3nitric oxide synthase 3, endothelial cell0.489
Mycnv-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)0.488
Fgf5fibroblast growth factor 50.480
Wt1Wilms tumor 1 homolog0.478
Pou3f3POU domain, class 3, transcription factor 30.463
Pdgfraplatelet derived growth factor receptor, alpha polypeptide0.434
Gdf5growth differentiation factor 50.434
Zeb1zinc finger E-box binding homeobox 10.424
Twist2twist homolog 2 (Drosophila)0.413
Msx2homeobox, msh-like 20.399
Alx4aristaless-like homeobox 40.397
Ctnnb1catenin (cadherin associated protein), beta 10.396
Gbx2gastrulation brain homeobox 20.394
Lhx1LIM homeobox protein 10.389
Smad4MAD homolog 4 (Drosophila)0.389
Scn5asodium channel, voltage-gated, type V, alpha0.372
Hmx3H6 homeobox 30.369
Wnt2bwingless related MMTV integration site 2b0.368
Wnt11wingless-related MMTV integration site 110.357
Gata5GATA binding protein 50.353
Barx1BarH-like homeobox 10.350
Dlx5distal-less homeobox 50.334
Vangl2vang-like 2 (van gogh, Drosophila)0.333
Phox2bpaired-like homeobox 2b0.326
Gscgoosecoid homeobox0.319
Nkx2-1NK2 homeobox 10.309
Msx1homeobox, msh-like 10.305
Rbpjrecombination signal binding protein for immunoglobulin kappa J region0.304
Pdx1pancreatic and duodenal homeobox 10.294
Foxd3forkhead box D30.290
Rarbretinoic acid receptor, beta0.288
Acanaggrecan0.286
Ptf1apancreas specific transcription factor, 1a0.285
En1engrailed 10.282
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Top2atopoisomerase (DNA) II alpha0.222
Pttg1pituitary tumor-transforming 10.033
Smad7SMAD family member 70.032
Kcng2potassium voltage-gated channel, subfamily G, member 20.029
Cks2CDC28 protein kinase regulatory subunit 20.022
Syt8synaptotagmin VIII0.021
Prl8a2prolactin family 8, subfamily a, member 20.021
Tgfbr2transforming growth factor, beta receptor II0.020
Col4a4collagen, type IV, alpha 40.017
Olr837olfactory receptor 8370.013
Serpine2serine (or cysteine) peptidase inhibitor, clade E, member 20.013
Nfianuclear factor I/A0.013
Hist1h1dhistone cluster 1, H1d0.013
Notch2Notch homolog 2 (Drosophila)0.012
Entpd1ectonucleoside triphosphate diphosphohydrolase 10.012
Ednraendothelin receptor type A0.011
Mpripmyosin phosphatase Rho interacting protein0.011
Kifc1kinesin family member C10.010
Mpp2membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)0.010
Slc10a2solute carrier family 10 (sodium/bile acid cotransporter family), member 20.010
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism