The network for 'granulocyte migration' in your query organism is displayed on the left, if relationships are supported by the integrated data. Moving any of the genes in that network will simultaneously update the homologs in the networks displayed to the right (if they exist). Additionally, hovering over any nodes will highlight the identified functionally similar homologs in the other networks. Last, the bar above the networks allows you to remove/add additional organisms. Simily drag and drop the organism names in the desired order.

Multiple Organisms

granulocyte migration

The movement of a granulocyte within or between different tissues and organs of the body.

NameDescriptionProbabilityFunc Analog Organism
NCF2neutrophil cytosolic factor 20.997
IL8interleukin 80.993
CCR5chemokine (C-C motif) receptor 50.986
CXCL1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.984
S100A9S100 calcium binding protein A90.969
S100BS100 calcium binding protein B0.962
PDGFRAplatelet-derived growth factor receptor, alpha polypeptide0.955
CCL4chemokine (C-C motif) ligand 40.949
FLT1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.947
S100A11S100 calcium binding protein A110.943
CXCL9chemokine (C-X-C motif) ligand 90.917
S100A6S100 calcium binding protein A60.901
GRB2growth factor receptor-bound protein 20.894
IL1Binterleukin 1, beta0.890
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)0.884
LCP2lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)0.869
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)0.868
PLCG1phospholipase C, gamma 10.866
CCR1chemokine (C-C motif) receptor 10.863
FCER1GFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.853
MPZL2myelin protein zero-like 20.853
CXCL3chemokine (C-X-C motif) ligand 30.852
CXCL10chemokine (C-X-C motif) ligand 100.850
PDGFRBplatelet-derived growth factor receptor, beta polypeptide0.848
VAV1vav 1 guanine nucleotide exchange factor0.842
CXCL2chemokine (C-X-C motif) ligand 20.840
CCL2chemokine (C-C motif) ligand 20.821
S100A14S100 calcium binding protein A140.820
TIMP1TIMP metallopeptidase inhibitor 10.778
SYKspleen tyrosine kinase0.773
S100A8S100 calcium binding protein A80.772
ANXA2annexin A20.752
ARHGDIBRho GDP dissociation inhibitor (GDI) beta0.737
CCR2chemokine (C-C motif) receptor 20.733
CDC42cell division cycle 42 (GTP binding protein, 25kDa)0.706
S100A16S100 calcium binding protein A160.695
MPZL3myelin protein zero-like 30.695
CCL5chemokine (C-C motif) ligand 50.695
IFNGinterferon, gamma0.693
FGRGardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog0.680
IL6interleukin 6 (interferon, beta 2)0.634
CCL19chemokine (C-C motif) ligand 190.621
CXCL5chemokine (C-X-C motif) ligand 50.617
SH3BP2SH3-domain binding protein 20.605
NRP1neuropilin 10.586
CXCR4chemokine (C-X-C motif) receptor 40.577
CCL22chemokine (C-C motif) ligand 220.540
CCL8chemokine (C-C motif) ligand 80.527
FCGR2AFc fragment of IgG, low affinity IIa, receptor (CD32)0.526
S100A4S100 calcium binding protein A40.485
IL12Binterleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)0.482
HCKhemopoietic cell kinase0.474
FCGR3BFc fragment of IgG, low affinity IIIb, receptor (CD16b)0.470
PECAM1platelet/endothelial cell adhesion molecule0.454
LST1leukocyte specific transcript 10.426
S100A12S100 calcium binding protein A120.425
EMP3epithelial membrane protein 30.413
KDRkinase insert domain receptor (a type III receptor tyrosine kinase)0.399
MYD88myeloid differentiation primary response gene (88)0.392
TFF1trefoil factor 10.386
TREM1triggering receptor expressed on myeloid cells 10.369
VCAM1vascular cell adhesion molecule 10.367
CCL20chemokine (C-C motif) ligand 200.366
IL10interleukin 100.366
LCKlymphocyte-specific protein tyrosine kinase0.362
DPP4dipeptidyl-peptidase 40.360
CYBBcytochrome b-245, beta polypeptide0.356
HLA-DQA1major histocompatibility complex, class II, DQ alpha 10.355
PTGS2prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)0.355
ITGB2integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)0.331
LGALS1lectin, galactoside-binding, soluble, 10.331
VEGFAvascular endothelial growth factor A0.328
CXCL6chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)0.318
PARD3par-3 partitioning defective 3 homolog (C. elegans)0.314
IL1R2interleukin 1 receptor, type II0.313
CXCL13chemokine (C-X-C motif) ligand 130.308
CXCL11chemokine (C-X-C motif) ligand 110.306
PDGFBplatelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog)0.299
S100A1S100 calcium binding protein A10.285
CCL7chemokine (C-C motif) ligand 70.274
FCN1ficolin (collagen/fibrinogen domain containing) 10.270
IL10RAinterleukin 10 receptor, alpha0.267
CLEC7AC-type lectin domain family 7, member A0.267
SLC11A1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.267
AQP9aquaporin 90.260
IL2RBinterleukin 2 receptor, beta0.260
MDM2Mdm2 p53 binding protein homolog (mouse)0.255
PTGIRprostaglandin I2 (prostacyclin) receptor (IP)0.248
ITGALintegrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)0.233
TGIF1TGFB-induced factor homeobox 10.225
TGFBR2transforming growth factor, beta receptor II (70/80kDa)0.223
LATlinker for activation of T cells0.215
ERBB2v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)0.201
MMP9matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)0.199
CCR7chemokine (C-C motif) receptor 70.198
MMP2matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)0.197
ITGB3integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)0.191
GAS7growth arrest-specific 70.190
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Caenorhabditis elegans
NameDescriptionProbabilityFunc Analog Organism
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Danio rerio
NameDescriptionProbabilityFunc Analog Organism
kdrlkinase insert domain receptor like0.958
spi1spleen focus forming virus (SFFV) proviral integration oncogene spi10.536
lcp1lymphocyte cytosolic plastin 10.523
csf3rcolony stimulating factor 3 receptor (granulocyte)0.407
cdh5cadherin 50.383
ptprcprotein tyrosine phosphatase, receptor type, C0.313
mmp9matrix metalloproteinase 90.232
mpxmyeloid-specific peroxidase0.212
ptpn6protein tyrosine phosphatase, non-receptor type 60.138
csf1racolony stimulating factor 1 receptor, a0.136
btkBruton agammaglobulinemia tyrosine kinase0.111
etv2ets variant gene 20.083
nod1nucleotide-binding oligomerization domain containing 10.081
ncf1neutrophil cytosolic factor 10.076
nr3c1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)0.075
coro1acoronin, actin binding protein, 1A0.075
itm2bbintegral membrane protein 2Bb0.074
ighzimmunoglobulin heavy constant zeta0.073
wasbWiskott-Aldrich syndrome (eczema-thrombocytopenia) b0.071
card9caspase recruitment domain family, member 90.070
st14asuppression of tumorigenicity 14 (colon carcinoma) a0.069
mmp13amatrix metalloproteinase 13a0.069
lrrc33leucine rich repeat containing 330.059
postnperiostin, osteoblast specific factor0.058
myd88myeloid differentiation primary response gene (88)0.048
krml2.2Kreisler (mouse) maf-related leucine zipper homolog 2.20.048
lta4hleukotriene A4 hydrolase0.047
jam2ajunctional adhesion molecule 2a0.043
vegfaavascular endothelial growth factor Aa0.043
fn1fibronectin 10.040
yrkYes-related kinase0.038
pth1aparathyroid hormone 1a0.038
fli1bfriend leukemia integration 1b0.037
ctssb.2cathepsin S, b.20.037
fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.036
ptger2aprostaglandin E receptor 2a (subtype EP2)0.036
ints6integrator complex subunit 60.033
fli1afriend leukemia integration 1a0.033
fabp11afatty acid binding protein 11a0.031
flncbfilamin C, gamma b (actin binding protein 280)0.030
dll4delta-like 4 (Drosophila)0.029
cdh1cadherin 1, epithelial0.029
spi1lspleen focus forming virus (SFFV) proviral integration oncogene spi1 like0.029
tie1endothelium-specific receptor tyrosine kinase 10.027
dzip1DAZ interacting protein 10.027
mcambmelanoma cell adhesion molecule b0.025
cmybtranscription factor cmyb0.025
ghrlghrelin/obestatin preprohormone0.024
osr1odd-skipped related 1 (Drosophila)0.024
appl1adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 10.024
plxnd1plexin D10.023
hspb6heat shock protein, alpha-crystallin-related, b60.023
nkd2naked cuticle homolog 2 and naked 2a0.023
wtipWilms tumor 1 interacting protein0.023
sp2sp2 transcription factor0.022
tie2endothelium-specific receptor tyrosine kinase 20.021
nfkbiaanuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a0.021
tnfatumor necrosis factor a (TNF superfamily, member 2)0.021
grap2bGRB2-related adaptor protein 2b0.021
metap2methionyl aminopeptidase 20.021
ikzf1IKAROS family zinc finger 1 (Ikaros)0.021
spns2spinster homolog 2 (Drosophila)0.020
wt1bwilms tumor 1b0.020
fevFEV (ETS oncogene family)0.020
mpzl2myelin protein zero-like 20.020
epas1bendothelial PAS domain protein 1b0.020
rnaset2lribonuclease T2, like0.020
ryr3ryanodine receptor 30.019
esrp2epithelial splicing regulatory protein 20.019
LOC557072caspase recruitment domain-containing protein 11-like0.018
tm4sf4transmembrane 4 L six family member 40.018
flt1fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)0.018
tgfbr2transforming growth factor, beta receptor II0.018
ltkleukocyte tyrosine kinase0.018
foxc1aforkhead box C1a0.018
tmprss4atransmembrane protease, serine 4a0.018
lndc1ly6/neurotoxin domain containing 10.018
itga5integrin, alpha 5 (fibronectin receptor, alpha polypeptide)0.018
myod1myogenic differentiation 10.018
capzbcapping protein (actin filament) muscle Z-line, beta0.017
lama1laminin, alpha 10.017
nphs1lnephrosis 1, congenital, Finnish type (nephrin)-like0.017
gata1aGATA binding protein 1a0.017
smtnbsmoothelin b0.016
nkd1naked cuticle homolog 1 (Drosophila)0.016
ntrk3bneurotrophic tyrosine kinase, receptor, type 3b0.016
mcoln1mucolipin 10.016
kdrkinase insert domain receptor (a type III receptor tyrosine kinase)0.016
gcm2glial cells missing homolog 2 (Drosophila)0.016
sla1Src-like-adaptor 10.016
wasaWiskott-Aldrich syndrome (eczema-thrombocytopenia) a0.016
ccbe1collagen and calcium binding EGF domains 10.015
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Drosophila melanogaster
NameDescriptionProbabilityFunc Analog Organism
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Mus musculus
NameDescriptionProbabilityFunc Analog Organism
Ccl2chemokine (C-C motif) ligand 20.998
Ccr2chemokine (C-C motif) receptor 20.997
Ccr1chemokine (C-C motif) receptor 10.990
Cd44CD44 antigen0.988
Selpselectin, platelet0.978
Lyz2lysozyme 20.966
Itgb3integrin beta 30.886
Fcgr1Fc receptor, IgG, high affinity I0.849
Csf1colony stimulating factor 1 (macrophage)0.822
S100a8S100 calcium binding protein A8 (calgranulin A)0.805
Il1rninterleukin 1 receptor antagonist0.781
Csf3rcolony stimulating factor 3 receptor (granulocyte)0.781
Vav1vav 1 oncogene0.766
Il1binterleukin 1 beta0.762
Mmp9matrix metallopeptidase 90.762
Ptprcprotein tyrosine phosphatase, receptor type, C0.757
Itgb1integrin beta 1 (fibronectin receptor beta)0.728
Cd40CD40 antigen0.676
Cxcr2chemokine (C-X-C motif) receptor 20.662
Seleselectin, endothelial cell0.656
Tnfrsf1btumor necrosis factor receptor superfamily, member 1b0.655
Cdh5cadherin 50.622
Cxcl2chemokine (C-X-C motif) ligand 20.610
C3ar1complement component 3a receptor 10.607
Apoeapolipoprotein E0.602
Fcer1gFc receptor, IgE, high affinity I, gamma polypeptide0.587
Il1ainterleukin 1 alpha0.566
Mmp8matrix metallopeptidase 80.538
Ccl4chemokine (C-C motif) ligand 40.509
FgrGardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog0.500
Itgaxintegrin alpha X0.496
Slfn1schlafen 10.493
S100a9S100 calcium binding protein A9 (calgranulin B)0.493
Itgalintegrin alpha L0.477
Mmp12matrix metallopeptidase 120.476
Thbs1thrombospondin 10.467
Itgb2integrin beta 20.453
Ccl3chemokine (C-C motif) ligand 30.446
Has1hyaluronan synthase10.442
Tgfb1transforming growth factor, beta 10.438
H2-Aahistocompatibility 2, class II antigen A, alpha0.430
Nos2nitric oxide synthase 2, inducible0.427
Cd180CD180 antigen0.405
Irg1immunoresponsive gene 10.393
Ccl12chemokine (C-C motif) ligand 120.370
AF251705cDNA sequence AF2517050.369
H2-Ab1histocompatibility 2, class II antigen A, beta 10.363
Cybbcytochrome b-245, beta polypeptide0.361
Il7rinterleukin 7 receptor0.359
Sfpi1SFFV proviral integration 10.357
Icam1intercellular adhesion molecule 10.355
Cx3cr1chemokine (C-X3-C) receptor 10.348
Bdkrb1bradykinin receptor, beta 10.339
Acvrl1activin A receptor, type II-like 10.322
Itgamintegrin alpha M0.318
Msr1macrophage scavenger receptor 10.317
Tlr2toll-like receptor 20.316
Nr3c1nuclear receptor subfamily 3, group C, member 10.310
Fpr3formyl peptide receptor 30.282
Nos3nitric oxide synthase 3, endothelial cell0.278
Cxcl1chemokine (C-X-C motif) ligand 10.274
Clec4dC-type lectin domain family 4, member d0.273
Ccl17chemokine (C-C motif) ligand 170.272
Ifngr1interferon gamma receptor 10.246
Adam17a disintegrin and metallopeptidase domain 170.245
Nrp1neuropilin 10.242
Cd3eCD3 antigen, epsilon polypeptide0.236
Rock2Rho-associated coiled-coil containing protein kinase 20.234
Slfn4schlafen 40.231
C5ar1complement component 5a receptor 10.229
Ccl7chemokine (C-C motif) ligand 70.223
Sema6dsema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D0.222
Selplgselectin, platelet (p-selectin) ligand0.222
Gpr33G protein-coupled receptor 330.216
Mx2myxovirus (influenza virus) resistance 20.216
Lilrb3leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 30.214
Slc11a1solute carrier family 11 (proton-coupled divalent metal ion transporters), member 10.211
Il10interleukin 100.210
SrcRous sarcoma oncogene0.210
Gpr132G protein-coupled receptor 1320.206
Osmroncostatin M receptor0.205
Il10rainterleukin 10 receptor, alpha0.205
Nfe2l2nuclear factor, erythroid derived 2, like 20.201
BrafBraf transforming gene0.195
SpibSpi-B transcription factor (Spi-1/PU.1 related)0.195
Dlg1discs, large homolog 1 (Drosophila)0.194
Hif1ahypoxia inducible factor 1, alpha subunit0.194
Serpina3nserine (or cysteine) peptidase inhibitor, clade A, member 3N0.191
ItkIL2-inducible T-cell kinase0.188
Fpr1formyl peptide receptor 10.182
Clec4nC-type lectin domain family 4, member n0.180
Il1r1interleukin 1 receptor, type I0.176
Rac1RAS-related C3 botulinum substrate 10.175
Csf2rb2colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)0.175
Mmp3matrix metallopeptidase 30.172
Slc10a6solute carrier family 10 (sodium/bile acid cotransporter family), member 60.168
Plaurplasminogen activator, urokinase receptor0.168
Tgfb2transforming growth factor, beta 20.167
Sellselectin, lymphocyte0.167
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Rattus norvegicus
NameDescriptionProbabilityFunc Analog Organism
Socs3suppressor of cytokine signaling 30.846
Il6interleukin 60.836
Cxcl10chemokine (C-X-C motif) ligand 100.736
Ccl2chemokine (C-C motif) ligand 20.706
Ccl4chemokine (C-C motif) ligand 40.670
Cxcl2chemokine (C-X-C motif) ligand 20.650
Igsf6immunoglobulin superfamily, member 60.475
Cxcl1chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)0.457
Fcer1gFc fragment of IgE, high affinity I, receptor for; gamma polypeptide0.451
Slco2b1solute carrier organic anion transporter family, member 2b10.377
Tnftumor necrosis factor (TNF superfamily, member 2)0.285
Cd14CD14 molecule0.281
Ptafrplatelet-activating factor receptor0.273
Il2rbinterleukin 2 receptor, beta0.250
Lilrb4leukocyte immunoglobulin-like receptor, subfamily B, member 40.248
ArhgdibRho, GDP dissociation inhibitor (GDI) beta0.248
Cd86CD86 molecule0.243
Reg3gregenerating islet-derived 3 gamma0.243
Il1binterleukin 1 beta0.235
Neurl3neuralized homolog 3 (Drosophila)0.234
RT1-BaRT1 class II, locus Ba0.223
Il2rginterleukin 2 receptor, gamma0.182
Il1ainterleukin 1 alpha0.173
Ccl3chemokine (C-C motif) ligand 30.168
Cxcl3chemokine (C-X-C motif) ligand 30.163
Cd8aCD8a molecule0.160
Pla2g2aphospholipase A2, group IIA (platelets, synovial fluid)0.158
Hckhemopoietic cell kinase0.153
Mapk1mitogen activated protein kinase 10.146
Nkg7natural killer cell group 7 sequence0.142
Laptm5lysosomal protein transmembrane 50.115
Il1r2interleukin 1 receptor, type II0.110
Fcn1ficolin (collagen/fibrinogen domain containing) 10.096
Bcl2a1dB-cell leukemia/lymphoma 2 related protein A1d0.094
Itgamintegrin, alpha M0.093
Ccr2chemokine (C-C motif) receptor 20.090
Cd68Cd68 molecule0.089
F2rl1coagulation factor II (thrombin) receptor-like 10.079
Ccr5chemokine (C-C motif) receptor 50.075
Ccl7chemokine (C-C motif) ligand 70.071
Cd83CD83 molecule0.070
C5ar1complement component 5a receptor 10.067
Acap1ArfGAP with coiled-coil, ankyrin repeat and PH domains 10.066
TcrbT-cell receptor beta chain0.065
Il1rninterleukin 1 receptor antagonist0.064
St8sia4ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 40.064
Tgm1transglutaminase 1, K polypeptide0.058
Serpine1serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 10.054
Ptger4prostaglandin E receptor 4 (subtype EP4)0.053
Il2rainterleukin 2 receptor, alpha0.053
Ccl20chemokine (C-C motif) ligand 200.047
Timp1TIMP metallopeptidase inhibitor 10.045
Rab20RAB20, member RAS oncogene family0.045
Pld4phospholipase D family, member 40.045
Tcf4transcription factor 40.044
Cd69Cd69 molecule0.043
TyrobpTyro protein tyrosine kinase binding protein0.043
Anxa1annexin A10.040
Plauplasminogen activator, urokinase0.038
Il8rbinterleukin 8 receptor, beta0.037
Pspparotid secretory protein0.037
Cmtm7CKLF-like MARVEL transmembrane domain containing 70.035
Tbxas1thromboxane A synthase 1, platelet0.035
Cd4Cd4 molecule0.035
Mmp8matrix metallopeptidase 80.035
Cd37CD37 molecule0.034
Edn1endothelin 10.033
F13a1coagulation factor XIII, A1 polypeptide0.031
Icam1intercellular adhesion molecule 10.030
Serpinb2serpin peptidase inhibitor, clade B (ovalbumin), member 20.030
Tmem171transmembrane protein 1710.029
Adora2aadenosine A2a receptor0.029
Tnfsf4tumor necrosis factor (ligand) superfamily, member 40.029
Il9rinterleukin 9 receptor0.028
Pstpip1proline-serine-threonine phosphatase-interacting protein 10.028
Ccrl2chemokine (C-C motif) receptor-like 20.027
Seleselectin E0.027
LOC100361571keratin associated protein 1-3-like0.027
Ccr3chemokine (C-C motif) receptor 30.027
Plcb2phospholipase C, beta 20.026
Olr1500olfactory receptor 15000.026
Cxcr3chemokine (C-X-C motif) receptor 30.025
Capgcapping protein (actin filament), gelsolin-like0.025
Ms4a2membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)0.024
Clec2dC-type lectin domain family 2, member d0.024
Cd44Cd44 molecule0.023
RT1-DaRT1 class II, locus Da0.023
Mmp10matrix metallopeptidase 100.023
Htr1b5-hydroxytryptamine (serotonin) receptor 1B0.023
Iappislet amyloid polypeptide0.022
Zbp1Z-DNA binding protein 10.022
Fam65bfamily with sequence similarity 65, member B0.021
Cpa3carboxypeptidase A3, mast cell0.021
Tspotranslocator protein0.021
MefvMediterranean fever0.021
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Saccharomyces cerevisiae
NameDescriptionProbabilityFunc Analog Organism